LOCUS       NM_152458               3208 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens zinc finger protein 785 (ZNF785), mRNA.
ACCESSION   NM_152458
VERSION     NM_152458.7
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3208)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 3208)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 3208)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3208)
  AUTHORS   Loftus,B.J., Kim,U.J., Sneddon,V.P., Kalush,F., Brandon,R.,
            Fuhrmann,J., Mason,T., Crosby,M.L., Barnstead,M., Cronin,L.,
            Deslattes Mays,A., Cao,Y., Xu,R.X., Kang,H.L., Mitchell,S.,
            Eichler,E.E., Harris,P.C., Venter,J.C. and Adams,M.D.
  TITLE     Genome duplications and other features in 12 Mb of DNA sequence
            from human chromosome 16p and 16q
  JOURNAL   Genomics 60 (3), 295-308 (1999)
   PUBMED   10493829
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN401082.1, BC040642.2 and AC002310.1.
            
            On May 17, 2019 this sequence version replaced NM_152458.6.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803611.163356.1,
                                           SRR1660807.119533.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000395216.3/ ENSP00000378642.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 CN401082.1         75-82
            9-1746              BC040642.2         1-1738
            1747-3208           AC002310.1         5630-7091
FEATURES             Location/Qualifiers
     source          1..3208
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p11.2"
     gene            1..3208
                     /gene="ZNF785"
                     /gene_synonym="ZNF688"
                     /note="zinc finger protein 785"
                     /db_xref="GeneID:146540"
                     /db_xref="HGNC:HGNC:26496"
     exon            1..291
                     /gene="ZNF785"
                     /gene_synonym="ZNF688"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..1304
                     /gene="ZNF785"
                     /gene_synonym="ZNF688"
                     /note="Zinc finger protein 688"
                     /codon_start=1
                     /product="zinc finger protein 785"
                     /protein_id="NP_689671.2"
                     /db_xref="CCDS:CCDS10685.1"
                     /db_xref="GeneID:146540"
                     /db_xref="HGNC:HGNC:26496"
                     /translation="MGPPLAPRPAHVPGEAGPRRTRESRPGAVSFADVAVYFSPEEWE
                     CLRPAQRALYRDVMRETFGHLGALGFSVPKPAFISWVEGEVEAWSPEAQDPDGESSAA
                     FSRGQGQEAGSRDGNEEKERLKKCPKQKEVAHEVAVKEWWPSVACPEFCNPRQSPMNP
                     WLKDTLTRRLPHSCPDCGRNFSYPSLLASHQRVHSGERPFSCGQCQARFSQRRYLLQH
                     QFIHTGEKPYPCPDCGRRFRQRGSLAIHRRAHTGEKPYACSDCKSRFTYPYLLAIHQR
                     KHTGEKPYSCPDCSLRFAYTSLLAIHRRIHTGEKPYPCPDCGRRFTYSSLLLSHRRIH
                     SDSRPFPCVECGKGFKRKTALEAHRWIHRSCSERRAWQQAVVGRSEPIPVLGGKDPPV
                     HFRHFPDIFQECG"
     exon            292..420
                     /gene="ZNF785"
                     /gene_synonym="ZNF688"
                     /inference="alignment:Splign:2.1.0"
     exon            421..3208
                     /gene="ZNF785"
                     /gene_synonym="ZNF688"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2331..2336
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF785"
                     /gene_synonym="ZNF688"
                     /note="hexamer: GATAAA"
     polyA_site      2358
                     /gene="ZNF785"
                     /gene_synonym="ZNF688"
     regulatory      2974..2979
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF785"
                     /gene_synonym="ZNF688"
                     /note="hexamer: AATAAA"
     regulatory      2989..2994
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF785"
                     /gene_synonym="ZNF688"
                     /note="hexamer: ATTAAA"
     polyA_site      3001
                     /gene="ZNF785"
                     /gene_synonym="ZNF688"
     polyA_site      3009
                     /gene="ZNF785"
                     /gene_synonym="ZNF688"
                     /note="major polyA site"
ORIGIN      
        1 acggacttgt ctgaggaaag acaggaaagc gccagcatct ccaccttccc cggaagcctc
       61 cctttgccag gcagaaaggg tttcccatgg ggccgcccct ggcgccgcgc ccggcccacg
      121 tacccgggga ggccgggccc cggaggacga gggaaagcag gccgggcgcc gtgagcttcg
      181 cggacgtggc cgtgtacttc tctcccgagg agtgggaatg cctgcggcca gcgcagaggg
      241 ccctgtaccg ggacgtgatg cgggagacct tcggccacct gggcgcgctg ggattttcag
      301 ttcccaaacc cgcttttatc tcgtgggtgg aaggagaagt ggaggcgtgg agcccggagg
      361 cccaggatcc cgacggtgag agctctgcag ctttcagcag gggccaagga caggaagcag
      421 gatccaggga tgggaatgag gagaaggaaa ggctgaagaa gtgtccaaaa caaaaagagg
      481 tggcgcatga agtggctgtc aaggagtggt ggcccagcgt cgcctgccca gagttctgca
      541 accctaggca gagccccatg aatccctggc tcaaggacac tctgacccga agactgcccc
      601 actcttgccc agactgtggc cgcaacttca gctacccttc cctcctggcc agccaccagc
      661 gggtccactc cggggagcgg cccttctcct gcggccagtg tcaggcgcgt ttctcccagc
      721 gcaggtacct gctccagcat cagttcatcc acaccggcga gaagccctac ccctgccccg
      781 actgcgggcg ccgcttccgc cagaggggtt ccctggctat ccacaggcgg gctcacaccg
      841 gggagaagcc ttacgcgtgc tcagactgca agagtcgctt cacttacccc tacctgctgg
      901 ccatccacca gcgcaagcac acgggcgaga agccctacag ctgccccgat tgcagcctcc
      961 gtttcgccta cacctccctg ctggccatcc acaggcgcat acacaccggc gagaagccct
     1021 acccctgtcc tgactgcggc cgccgcttca cctattcttc cctcctcctc agtcaccggc
     1081 gcattcactc cgacagccgg cccttcccct gcgtggagtg tgggaaaggc ttcaagcgca
     1141 agaccgccct ggaagcccat cggtggatcc accgctcctg cagcgagagg cgcgcgtggc
     1201 agcaggccgt ggtggggcgt tcagagccca tccctgtttt gggaggcaag gatcccccag
     1261 ttcacttccg gcactttcca gatatatttc aagagtgtgg gtgatggcgt tcacacaaac
     1321 tggtcagcgt ttccctggag aggaagaggc aaggtttgtg tatttggggg ataaggaaag
     1381 gaagtgggcg tttgaggaaa acaaagttct gccttaggta aaaagcagag gtaggggcac
     1441 agagggctgt ggggaggagg caggaatctg aaaaggtgcc tgggggttga ccccattttc
     1501 tgaagctcca gcacacaggg ccccgtgttc acgtcccatc cttcactgaa aaccattcac
     1561 ctaactggct tttccttcat gattgttctc tcccttgtag ctctctgctt tttggcctgt
     1621 atctctccta ctcctctgag atggggtccc ctacattcca gtgcctatta aaggagcctg
     1681 cacccactct ggacccccca gaatagaggg gatacctcag gcctgtccct cggctggtgg
     1741 ggggggcgga gctcatccca ggattctttt cttttttttg agatggagtc atgctctgtc
     1801 gcccaggctg gagtgcagtg gcgtgatctc ggctcactgc aacctctgcc tcctgggttc
     1861 aagccattct ctgcctcagc cttcccatta gctgggatta caggcatgcg ccaccaggcc
     1921 cagctaattt ttgtgctgtt agtagagacg gggttccacc atcttggcca ggctggtctt
     1981 gaattcctga cctcgtgatc cacccgcctc ggcgtctcaa agtgctggga ttacaagcgt
     2041 gagccaccga cccctgccga ggattctgcc ttttaccaat gcaggtgaaa catctggcaa
     2101 ggagacacct ggagtgtagg tgttccttgg tcttgaagac ctagaggtgg ccatagagag
     2161 gacagtggcc tcaggtgggg aactcccccc ccactctcat tctgcaagtg cacaaactat
     2221 caaacatagc ggactctgga actgggccaa ctcttcactg tatgcattag tgattgcagt
     2281 gtttttttct tcttcagata tttgcatgtt ccctggattt tgtatttttt gataaagata
     2341 tattcttggg ccacagtagc tggagatata atgccggagg attctttttt tttttttttt
     2401 ttttgagaca gagtctgtct ctattgcctg ggctggagtg cagtggccca agctacgctc
     2461 actgcaagct ccacctcctg ggttcacacc attctcctgc ttcagtctcc cgagtagctg
     2521 gaattacaag cacccgccac cacgcccaac taatattttg tatttttagt agagacgggg
     2581 gtttcaccgt gttagccagg atggtctcga tctcctgact tcgtgatcct cccgcctcgg
     2641 cctcccaaag tgctgggatt acaggcgtga gccactgcac ccagcctctt tttttttttg
     2701 agatggagtt tcgctcttgt tgcccaggct agagtgcaat ggcatgatct tggctcactg
     2761 caacctccgc ctcctaggtt caagcgattc tcctgcccca gcctcttgag tagctgggat
     2821 tacaggcacc cacgaccatg cctggctaat tgcattttta ctagagacag gtttcaccat
     2881 gttggccagg ctggtctcca attcctgacc tcaggtgatc cacccgactt ggcctcccaa
     2941 agttctggga ttacattttt tttttaaaga aagaataaat taattgtgat taaagttgaa
     3001 atcaaggcat agtctttcca gtctaatttt tactgtaatg cttgtatgtc aacagttatg
     3061 aaggccaggc gcggtggctc acgcctgtaa tcctagcagt ttgggaggct gaggagggtg
     3121 gatcacttaa ggtcaagagt tcaagaccag cctggccaat atggtgaaac cccatctcta
     3181 ctaaaaatac caaaaaaaaa aaaaaaaa
//
