LOCUS       NM_001001662            4442 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 782 (ZNF782), transcript variant
            1, mRNA.
ACCESSION   NM_001001662 XM_098940
VERSION     NM_001001662.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4442)
  AUTHORS   Lei,S.F., Yang,T.L., Tan,L.J., Chen,X.D., Guo,Y., Guo,Y.F.,
            Zhang,L., Liu,X.G., Yan,H., Pan,F., Zhang,Z.X., Peng,Y.M., Zhou,Q.,
            He,L.N., Zhu,X.Z., Cheng,J., Liu,Y.Z., Papasian,C.J. and Deng,H.W.
  TITLE     Genome-wide association scan for stature in Chinese: evidence for
            ethnic specific loci
  JOURNAL   Hum Genet 125 (1), 1-9 (2009)
   PUBMED   19030899
  REMARK    GeneRIF: The present results suggest that the genomic region
            containing the ZNP510 and ZNP782 genes is an ethnic specific locus
            associated with stature variation in Chinese.
            GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL158827.27, AL540705.3 and AK131468.1.
            
            On May 17, 2019 this sequence version replaced NM_001001662.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a). Variants 1 and 2
            both encode the same isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK131468.1, BC137073.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000481138.6/ ENSP00000419397.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AL158827.27        54126-54151         c
            27-89               AL540705.3         1-63
            90-91               AL158827.27        54061-54062         c
            92-407              AL540705.3         64-379
            408-3720            AK131468.1         1-3313
            3721-4442           AL158827.27        15906-16627         c
FEATURES             Location/Qualifiers
     source          1..4442
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q22.33"
     gene            1..4442
                     /gene="ZNF782"
                     /note="zinc finger protein 782"
                     /db_xref="GeneID:158431"
                     /db_xref="HGNC:HGNC:33110"
     exon            1..427
                     /gene="ZNF782"
                     /inference="alignment:Splign:2.1.0"
     exon            428..644
                     /gene="ZNF782"
                     /inference="alignment:Splign:2.1.0"
     exon            645..703
                     /gene="ZNF782"
                     /inference="alignment:Splign:2.1.0"
     CDS             689..2788
                     /gene="ZNF782"
                     /note="isoform a is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 782 isoform a"
                     /protein_id="NP_001001662.1"
                     /db_xref="CCDS:CCDS35075.1"
                     /db_xref="GeneID:158431"
                     /db_xref="HGNC:HGNC:33110"
                     /translation="MNTFQASVSFQDVTVEFSQEEWQHMGPVERTLYRDVMLENYSHL
                     VSVGYCFTKPELIFTLEQGEDPWLLEKEKGFLSRNSPEDSQPDEISEKSPENQGKHLL
                     QVLFTNKLLTTEQEISGKPHNRDINIFRARMMPCKCDIAGSACQGLSLMAPHCQYSKE
                     KAHERNVCDKWLISIKDGRTNTQEKSFAYSKIVKTLHHKEEVIQHQTIQTLGQDFEYN
                     ESRKAFLEKAALVTSNSTHPKGKSYNFNKFGENKYDKSTFIIPQNMNPEKSHYEFNDT
                     GNCFCRITHKTLTGGKSFSQKSHIREHHRVHIGVKPFEYGKSFNRNSTLPVHQRTHAT
                     DKYSDYHPCTETFSYQSTFSVHQKVHIRAKPYEYNECGKSCSMNSHLIWPQKSHTGEK
                     PYECPECGKAFSEKSRLRKHQRTHTGEKPYKCDGCDKAFSAKSGLRIHQRTHTGEKPF
                     ECHECGKSFNYKSILIVHQRTHTGEKPFECNECGKSFSHMSGLRNHRRTHTGERPYKC
                     DECGKAFKLKSGLRKHHRTHTGEKPYKCNQCGKAFGQKSQLRGHHRIHTGEKPYKCNH
                     CGEAFSQKSNLRVHHRTHTGEKPYQCEECGKTFRQKSNLRGHQRTHTGEKPYECNECG
                     KAFSEKSVLRKHQRTHTGEKPYNCNQCGEAFSQKSNLRVHQRTHTGEKPYKCDKCGRT
                     FSQKSSLREHQKAHPGD"
     exon            704..830
                     /gene="ZNF782"
                     /inference="alignment:Splign:2.1.0"
     exon            831..932
                     /gene="ZNF782"
                     /inference="alignment:Splign:2.1.0"
     exon            933..4442
                     /gene="ZNF782"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4193..4198
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF782"
                     /note="hexamer: AATAAA"
     regulatory      4218..4223
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF782"
                     /note="hexamer: AATAAA"
     polyA_site      4219
                     /gene="ZNF782"
     regulatory      4227..4232
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF782"
                     /note="hexamer: CATAAA"
     polyA_site      4239
                     /gene="ZNF782"
                     /note="major polyA site"
     polyA_site      4252
                     /gene="ZNF782"
     regulatory      4423..4428
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF782"
                     /note="hexamer: AACAAA"
     polyA_site      4442
                     /gene="ZNF782"
ORIGIN      
        1 agagccccgc ctcctcattt gggttctcga gactcccggg aagcggtttg ggaagctcgg
       61 gggtcggctc ggaaagtaga gggggcgcag ctggggcggg aggacagcgt ttgtgcccgg
      121 aagcgggaga ggaagcggga agtttgtggg atccccgccc cctgtgtcag tggatgcgac
      181 cgggcgggcc ctcggccttc ccggccgctg gagagggact tcggccgctg gctcccgggg
      241 cggctgaggc tgagcgttgg tccggagcag gtgccgggtg cgggccgcgg tgtgcgggac
      301 cggagcccgg cgcgagcggc ggcgggggtg gggaaagcgc atttgtaacg cgggcgacaa
      361 cgtgcccgaa atccccggac ggtgggtctg catcgagacc ccgagctctg gagctggaaa
      421 aacccggatg ccatactgct gttaacatat gtgacactgg agactttgtc cctacctcat
      481 agaatcccat gcatgatgat acatgaaggg ttttccgtgg ctatctactt ctgattcttt
      541 tgaaagcttt aaagacattg ggcatgaaag gttcagtgag tttccgggga tccctcgttt
      601 gtggtagagc caggaggaaa acagttccgt tcattctttc acagctgagg ctttacagtt
      661 ctctatactc tcccaagagc cacagaaaat gaacacattt caggcatcag tgtcattcca
      721 ggacgtgact gtggaattca gccaggagga gtggcagcac atgggccctg ttgagaggac
      781 cctgtacaga gatgtgatgc tggagaacta cagccacctc gtctcagtgg gctactgctt
      841 tacaaaacca gaactgatct tcacattgga acaaggagaa gatccatggt tattagagaa
      901 agagaaagga tttctaagca ggaactcccc agaagactcc caacctgatg aaatctcaga
      961 gaagagccca gaaaatcaag gcaaacattt gttgcaagtt ttattcacca ataaattatt
     1021 gactacagag caagaaattt caggaaaacc acataatcga gacataaaca tttttcgtgc
     1081 aagaatgatg ccttgtaaat gtgacattgc ggggtctgct tgccaggggc tcagcctgat
     1141 ggccccacac tgtcagtatt caaaagaaaa ggctcatgag cgtaatgttt gtgacaaatg
     1201 gctcatcagt attaaggatg gcagaactaa cactcaagag aaatctttcg cttatagtaa
     1261 aattgtgaaa accctccatc ataaggagga agttattcaa catcagacaa ttcagactct
     1321 ggggcaagat tttgaatata atgaaagtag aaaagctttt cttgaaaagg ctgcccttgt
     1381 tacatctaac agtacccacc caaaaggaaa atcttacaat ttcaataaat ttggggaaaa
     1441 caaatatgat aaatcaacct ttattattcc tcagaacatg aatccagaga agagtcacta
     1501 tgagtttaat gatactggaa attgtttctg tagaatcact cacaaaactc tcacaggagg
     1561 gaaatccttc agccaaaagt cacacattag agaacatcat agagttcata taggggtgaa
     1621 accctttgaa tatggaaaaa gtttcaaccg taattcaacc ctcccagtgc atcagagaac
     1681 tcatgcaaca gataaatact ctgattatca cccatgtaca gagacattca gctaccagtc
     1741 aactttcagt gtacatcaga aggttcacat aagggcaaaa ccctatgagt ataatgaatg
     1801 tgggaaatcc tgctctatga attcacactt gatttggcct cagaaaagtc acacagggga
     1861 gaaaccctat gaatgtcctg agtgcgggaa agccttcagt gagaagtcac gcctaagaaa
     1921 acatcagaga actcacacgg gagagaaacc atacaaatgt gatggatgtg ataaagcttt
     1981 cagtgcaaag tcaggcctaa gaatacacca gagaacccac acaggggaga aaccattcga
     2041 atgtcatgaa tgtgggaaat cttttaacta taagtcaatc ctcatagtgc atcagagaac
     2101 tcacacaggg gagaaacctt ttgaatgtaa tgaatgcggg aaatctttca gccatatgtc
     2161 aggcctaagg aatcaccgaa gaactcacac aggggaaaga ccatataaat gtgatgaatg
     2221 tgggaaagct ttcaaactga agtcaggcct gaggaaacat catagaacac acacagggga
     2281 gaagccctac aaatgtaatc agtgtggaaa agctttcggt cagaaatcac aactcagagg
     2341 acatcataga attcacacag gggaaaaacc ctataaatgt aatcattgtg gggaagcttt
     2401 cagtcagaaa tcaaacctca gagtacatca cagaactcat actggggaga aaccctatca
     2461 atgtgaggag tgtggaaaaa cattcaggca gaaatcaaat ctcagagggc atcagagaac
     2521 tcacactggg gagaagccct atgaatgtaa tgaatgtgga aaagctttca gtgagaagtc
     2581 agtcctaaga aaacatcagc gaactcacac cggggagaaa ccatataatt gtaatcagtg
     2641 tggggaagct ttcagtcaga aatccaatct cagagtacat cagagaactc acacagggga
     2701 gaaaccctat aaatgtgata aatgtgggag aactttcagt caaaaatcaa gccttagaga
     2761 acatcagaaa gcccacccag gggattaaat gtatgcatat aaagaatacg aaaaaactct
     2821 gagctggaaa tcaaacctca caatacataa atgaacacac aggagagaac tgttaacata
     2881 gtgagcactg gaatttcctc tacaatttca gcctccacca aatatcaaag aatagaagat
     2941 aaattgttga aatctatttt atatgggcat tctttcagcc agagcccagt cttctatgga
     3001 tatacagaac tcacacagca aagaaaccct ataaacataa tgaatatgga aaatactctt
     3061 gcgaactcac tcctcagaaa actcacgctg cagaaaagct ctgagaaagt aataaaaatg
     3121 tgaaaacttt gtgccaacaa tcaaaactca ttcaccatca gagaaatcac acaatgacaa
     3181 aagctagaat ataataagtg tgtgataaac tttaatgaaa agtcagtaca gcagaaaata
     3241 cattcaagat agagacctca tagtatatta aaacaaacaa gaaatgaagt taatggatgt
     3301 gggaaattct tctgccatgt caaccctcat tttaacctac acagaggtaa tccctatatg
     3361 tcgtataata actattgaaa tgttcactag taatcatttt cacttctccc tcatgccaca
     3421 cctggcctaa atttctcaac cactctctca tctaaacggg gtcatattgt taccctctag
     3481 ctagtggaat atggggtcag tgacaggtct taaatacatc agtcaaattc tcaatatttt
     3541 cttctatccc tcattagaat ggaatggagg aaaaccttgg gactcaggct ctgatgatgg
     3601 aaagtacaag atggtaggaa cccgggtcag agaaggatcc tgtggcatgg agttttctcc
     3661 tccctgtaca cagttggact tcttgcagtg aggaaataaa tgtgttccct gctgaacttc
     3721 taaaggtttg ggtatacttg atactgacag aaactcaaca accctcacat aataaaactt
     3781 aggagtatga tttttcagga catctgaact cagtgtatgt cagaaaagtc acataggaca
     3841 aatctcggac agcatcctga atgaccatgg cttttatccc caaagtcttc ctcatcagac
     3901 aggtaatatc ataagaaatc tgacatttta acaaatatag gaaattcttc acacacacag
     3961 acacacactc acacatacac acccaaagtc tcattaaata tatgataatt tagttttgaa
     4021 tgtgtaaaag ttttcaacaa attatcatat tttatatcag agcttgttac aaggagaaaa
     4081 tctatcaatt tgagaaaggt aagtaatagc ctttatctag atattgcttt atcagaactg
     4141 ttgtttcaca tataatatca aaacttttaa tgaaatataa gacattcact ataataaaaa
     4201 gcttaaaaag aacaaaaaat aaactgcata aactgaaaag cagtgttgca aatatgtgaa
     4261 tgttttgtga gttattgatt gtttatgtat gtatatatgc atggtactta ccaggtattt
     4321 gttttatgtt tcttagacct caacattgct gtaaaagaat tgtgttcccc ttgctttata
     4381 actactttga catcagctac aatttgccac atgaatatta ataacaaacc ttttacagaa
     4441 aa
//
