LOCUS       NM_015694               3172 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens zinc finger protein 777 (ZNF777), mRNA.
ACCESSION   NM_015694
VERSION     NM_015694.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3172)
  AUTHORS   Lovering,R.C., Gaudet,P., Acencio,M.L., Ignatchenko,A., Jolma,A.,
            Fornes,O., Kuiper,M., Kulakovskiy,I.V., Laegreid,A., Martin,M.J.
            and Logie,C.
  TITLE     A GO catalogue of human DNA-binding transcription factors
  JOURNAL   Biochim Biophys Acta Gene Regul Mech 1864 (11-12), 194765 (2021)
   PUBMED   34673265
REFERENCE   2  (bases 1 to 3172)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 3172)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 3172)
  AUTHORS   Al Chiblak,M., Steinbeck,F., Thiesen,H.J. and Lorenz,P.
  TITLE     DUF3669, a 'domain of unknown function' within ZNF746 and ZNF777,
            oligomerizes and contributes to transcriptional repression
  JOURNAL   BMC Mol Cell Biol 20 (1), 60 (2019)
   PUBMED   31856708
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3172)
  AUTHORS   Yuki,R., Aoyama,K., Kubota,S., Yamaguchi,N., Kubota,S.,
            Hasegawa,H., Morii,M., Huang,X., Liu,K., Williams,R., Fukuda,M.N.
            and Yamaguchi,N.
  TITLE     Overexpression of zinc-finger protein 777 (ZNF777) inhibits
            proliferation at low cell density through down-regulation of
            FAM129A
  JOURNAL   J Cell Biochem 116 (6), 954-968 (2015)
   PUBMED   25560148
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC073314.4, DR763452.1, BX444270.2, AB033111.1 and BC023985.2.
            
            On Nov 22, 2018 this sequence version replaced NM_015694.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000247930.5/ ENSP00000247930.4
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               AC073314.4         40010-40109         c
            101-152             DR763452.1         1-52
            153-186             BX444270.2         52-85
            187-2510            AB033111.1         1-2324
            2511-3172           BC023985.2         1475-2136
FEATURES             Location/Qualifiers
     source          1..3172
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q36.1"
     gene            1..3172
                     /gene="ZNF777"
                     /note="zinc finger protein 777"
                     /db_xref="GeneID:27153"
                     /db_xref="HGNC:HGNC:22213"
                     /db_xref="MIM:619298"
     exon            1..248
                     /gene="ZNF777"
                     /inference="alignment:Splign:2.1.0"
     exon            249..1109
                     /gene="ZNF777"
                     /inference="alignment:Splign:2.1.0"
     CDS             264..2759
                     /gene="ZNF777"
                     /codon_start=1
                     /product="zinc finger protein 777"
                     /protein_id="NP_056509.2"
                     /db_xref="CCDS:CCDS43675.1"
                     /db_xref="GeneID:27153"
                     /db_xref="HGNC:HGNC:22213"
                     /db_xref="MIM:619298"
                     /translation="MENQRSSPLSFPSVPQEETLRQAPAGLPRETLFQSRVLPPKEIP
                     SLSPTIPRQGSLPQTSSAPKQETSGRMPHVLQKGPSLLCSAASEQETSLQGPLASQEG
                     TQYPPPAAAEQEVSLLSHSPHHQEAPVHSPEAPEKDPLTLSPTVPETDMDPLLQSPVS
                     QKDTPFQISSAVQKEQPLPTAEITRLAVWAAVQAVERKLEAQAMRLLTLEGRTGTNEK
                     KIADCEKTAVEFANHLESKWVVLGTLLQEYGLLQRRLENMENLLKNRNFWILRLPPGS
                     NGEVPKVPVTFDDVAVHFSEQEWGNLSEWQKELYKNVMRGNYESLVSMDYAISKPDLM
                     SQMERGERPTMQEQEDSEEGETPTDPSAAHDGIVIKIEVQTNDEGSESLETPEPLMGQ
                     VEEHGFQDSELGDPCGEQPDLDMQEPENTLEESTEGSSEFSELKQMLVQQRNCTEGIV
                     IKTEEQDEEEEEEEEDELPQHLQSLGQLSGRYEASMYQTPLPGEMSPEGEESPPPLQL
                     GNPAVKRLAPSVHGERHLSENRGASSQQQRNRRGERPFTCMECGKSFRLKINLIIHQR
                     NHIKEGPYECAECEISFRHKQQLTLHQRIHRVRGGCVSPERGPTFNPKHALKPRPKSP
                     SSGSGGGGPKPYKCPECDSSFSHKSSLTKHQITHTGERPYTCPECKKSFRLHISLVIH
                     QRVHAGKHEVSFICSLCGKSFSRPSHLLRHQRTHTGERPFKCPECEKSFSEKSKLTNH
                     CRVHSRERPHACPECGKSFIRKHHLLEHRRIHTGERPYHCAECGKRFTQKHHLLEHQR
                     AHTGERPYPCTHCAKCFRYKQSLKYHLRTHTGE"
     exon            1110..1236
                     /gene="ZNF777"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1350
                     /gene="ZNF777"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1602
                     /gene="ZNF777"
                     /inference="alignment:Splign:2.1.0"
     exon            1603..3172
                     /gene="ZNF777"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3015..3020
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF777"
                     /note="hexamer: AATAAA"
     polyA_site      3034
                     /gene="ZNF777"
                     /note="major polyA site"
     regulatory      3151..3156
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF777"
                     /note="hexamer: AATAGA"
     polyA_site      3172
                     /gene="ZNF777"
                     /note="major polyA site"
ORIGIN      
        1 acatgaactc cgggctttct ctggtgtgac gggtttctta gatccctttg tgagcgcagg
       61 ttttgaaagg gaacgacccc gggttctggg tgtgagaggc gcaggggatc ggcgggagga
      121 aggctgtcgg agccaatcaa gccgcctcca gaccccagca cgtcgcctgg gctgcgcgct
      181 ccgactgcgc ctccgcccgc gcgcctcccg gcctcgcccg agggtgcctg ggcaggcgag
      241 gaccccaggt tcagcagctg gacatggaga accaacgctc atcacctctg tcgttcccca
      301 gtgttccaca agaagaaacc ttacgtcagg cccctgctgg actcccccga gaaactctgt
      361 tccaatcccg cgttcttcct cccaaagaaa ttccttcttt gtctcccacc attccccgtc
      421 aaggctccct gccccaaact tccagtgctc ccaagcaaga gacttctggc cggatgccac
      481 atgtgctcca gaagggaccc tcactcctgt gttctgccgc ttctgagcaa gagacttctc
      541 tccagggccc cctggcttcc caggaaggga cccagtatcc acccccagct gctgctgaac
      601 aagaagtctc ccttctctcc cactcccccc accaccagga agcccccgtt cactcccctg
      661 aagctcctga gaaagacccc ctgacccttt ccccaacagt tcccgagact gacatggacc
      721 cgctgctcca gagcccggtt tcccaaaagg acaccccttt ccagatctct tctgcagtcc
      781 agaaggaaca gccgctcccc acggcagaga tcacccgctt ggctgtgtgg gctgccgtcc
      841 aagcagtgga gaggaagctg gaggcccagg ccatgaggct actgaccctg gaaggcagga
      901 cggggacaaa tgaaaagaag atagccgact gcgagaagac agccgtggag ttcgcgaacc
      961 atctggagag caagtgggtc gtgttgggga ccctgctgca ggagtatggg ctgctgcaga
     1021 ggcggctgga gaacatggag aacctgctga aaaacagaaa tttctggatc ctgcggctgc
     1081 cccccggcag caatggagaa gttcccaagg tccctgtcac atttgatgat gttgctgtgc
     1141 acttctcgga gcaggagtgg ggaaacctgt ctgagtggca gaaggagctc tacaagaacg
     1201 tgatgagggg caactacgag tccctggttt ccatggacta tgcaatttcc aaaccagacc
     1261 tcatgtcaca gatggagcgc ggggagcggc ccaccatgca ggagcaggaa gactctgagg
     1321 agggcgaaac gccgacagat cccagtgctg cgcacgatgg gatcgtgatt aagatcgagg
     1381 tacagaccaa cgacgagggc tcagaaagtt tggagacacc tgagcccctg atgggacagg
     1441 tggaagagca cggcttccag gactcagagc tgggtgaccc ctgtggggaa cagccagacc
     1501 tggacatgca ggagccagag aacacgctgg aggagtccac ggaaggctcc agcgagttca
     1561 gcgaactgaa gcagatgctg gtgcagcaga ggaactgcac ggaggggatc gtgatcaaga
     1621 cagaggaaca agacgaggag gaagaagagg aggaggagga tgagctgccg cagcacttgc
     1681 aatcccttgg gcagctgtcc gggagatatg aggccagtat gtaccagacc ccgctgcccg
     1741 gggagatgtc ccccgagggc gaggagagcc ccccgcccct gcagctagga aaccccgcag
     1801 tgaaaaggct ggcgccctcc gtgcacggtg agcggcacct gagcgagaac cgcggggcct
     1861 cgagccagca gcagcggaac cggcgcggcg agcggccctt cacatgcatg gagtgcggca
     1921 agagcttccg cctgaagatc aacctcatca tccaccagcg caaccacatc aaggaggggc
     1981 cctacgagtg cgccgaatgc gagatcagct tccggcacaa gcaacagctc acgctgcacc
     2041 agcgcatcca ccgcgtgcgc ggaggctgcg tctcacccga acgcgggccc acgttcaacc
     2101 ccaagcacgc gctcaagccg cgtcccaagt cacccagctc tggtagcggc ggcggtggcc
     2161 ctaagcccta caagtgcccc gagtgcgaca gcagcttcag ccacaagtcc agcctgacca
     2221 aacaccagat cacgcacacg ggtgagcggc cctacacgtg ccccgagtgc aagaagagct
     2281 tccgcctgca catcagcttg gtgatccatc agcgcgtgca cgcgggcaag catgaggtct
     2341 ccttcatctg cagcctgtgc ggcaagagct tcagccgccc ctcgcacctg ctgcgccacc
     2401 agcggactca cacaggcgag cggcccttca agtgccccga gtgcgagaag agcttcagcg
     2461 agaagtccaa gctcaccaac cactgccgcg tgcactcgcg cgagcggccg cacgcctgcc
     2521 ccgagtgcgg caagagcttc atccgcaagc accacctcct ggaacaccgg cgcatccaca
     2581 caggcgagcg gccctaccac tgcgccgagt gcggcaagcg cttcacgcag aagcatcacc
     2641 tgctggagca ccagcgcgcg cacacgggcg agcggcccta cccctgcacg cactgcgcca
     2701 agtgcttccg ctacaagcag tcgctcaagt accacctgcg gacccacacg ggcgagtgag
     2761 cgcgcgcccc gccgccgccg cccggccagg tgcgcgggcc gtgccccccc tcggacaccg
     2821 ccaggcccga gcccagcggg cgggggcggg gcgcccccca gcccctttgc cgtgagctcc
     2881 ccctctcctc tcgtccctcc tcccaaggac atgggggcag tgagaccagg tcccttgctg
     2941 ccgcgtttcc ccgggggccc caggggggag ggcgcggacc tggggaaccc tttcgggctg
     3001 ttaatttcct tgacaataaa atggatgaaa ccaatcagca cggggggcgt gatttggccg
     3061 ccggccactc agaggggcgg tgtagggccc atctagttgg ggatagaact ttataattac
     3121 cttttggata ctgtggttct atttgataat aatagagtaa tttttaaaag aa
//
