LOCUS       NM_173632               5262 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 776 (ZNF776), transcript variant
            1, mRNA.
ACCESSION   NM_173632
VERSION     NM_173632.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5262)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK299680.1, BC136753.1, CR936802.1, AK127764.1 and AI446541.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_173632.3.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BP872602.1, SRR1660803.64264.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000317178.10/ ENSP00000321812.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1406              AK299680.1         20-1425
            1407-1937           BC136753.1         1068-1598
            1938-4631           CR936802.1         1911-4604
            4632-4918           AK127764.1         4295-4581
            4919-5262           AI446541.1         12-355              c
FEATURES             Location/Qualifiers
     source          1..5262
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..5262
                     /gene="ZNF776"
                     /note="zinc finger protein 776"
                     /db_xref="GeneID:284309"
                     /db_xref="HGNC:HGNC:26765"
     exon            1..277
                     /gene="ZNF776"
                     /inference="alignment:Splign:2.1.0"
     CDS             245..1801
                     /gene="ZNF776"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 776 isoform 1"
                     /protein_id="NP_775903.3"
                     /db_xref="CCDS:CCDS12962.2"
                     /db_xref="GeneID:284309"
                     /db_xref="HGNC:HGNC:26765"
                     /translation="MAAAALRPPAQGTVTFEDVAVNFSQEEWSLLSEAQRCLYHDVML
                     ENLTLISSLGCWYGAKDETPSKQTLSIQQESPLRTHWTGVCTKKVHLWGMCGPLLGDI
                     LHQGTQHNQKLNGFGAYEKKLDDDANHHQDQKQHIGEKSYRSNAKGTSFVKNCKFHMS
                     HEPFIFHEVGKDFLSSLRLLQQEDIHTSGKSNFETKHGIPLQGGKTHYICGESTIPFS
                     NKHSLVLHQRLLPREGPYVCSDSGKFTSKSNSFNNHQGVRTGKRPYQCGQCDESFWYK
                     AHLTEHQRVHTGERPYECGECDKSFSHKHSLVDHQRVHTGERPYECDECGKSFSHKRS
                     LVHHQRVHTGERPYQCGECGKSFNHKCNLIQHQRVHTGERPFECTACGKLFRSNSHLK
                     EHQRVHTGERPYECKECRKSFRYKSHLTEHQRVHTGERPYECRECGKCFHQKGSLIQH
                     QQIHSGERPHECGECGKCFHQKGSLIRHQQIHSGERPHECGECGKCFRQKGNLIKHQR
                     VHTGERHHEC"
     exon            278..404
                     /gene="ZNF776"
                     /inference="alignment:Splign:2.1.0"
     exon            405..5262
                     /gene="ZNF776"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5240..5245
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF776"
                     /note="hexamer: AATAAA"
     polyA_site      5262
                     /gene="ZNF776"
                     /note="major polyA site"
ORIGIN      
        1 agtggccatt ttgattggtg ttgggtgtat tttccagtga gagaccgcgg agtgttgggt
       61 cgtgtagaag tgactgaacc cagaaggtgg agacgagacg ttgtcccgac tgcacagagg
      121 ctgctctgca gctccttaaa ggcgctaggc gtgacccgca ccaaggccgg gatcgggacc
      181 accgtgcccg ggtacctgca ctgctcgccc cctcctttcg accccgcttt ccccacccag
      241 tcggatggcg gcggccgcgc tgaggccccc ggctcagggc actgtgacct ttgaagatgt
      301 ggctgtgaac ttttcccagg aggaatggag tctccttagt gaggctcaga gatgccttta
      361 tcatgacgtg atgctggaga acctgacact tatatcttct ctaggttgtt ggtatggagc
      421 aaaagacgag acaccttcta agcagaccct ttctatacaa caggagtccc cactcaggac
      481 acattggaca ggtgtatgta ccaagaaggt ccacctctgg ggaatgtgtg gccctctcct
      541 gggagatatc ttacaccagg gaacacaaca caatcagaaa ttgaatgggt ttggggcata
      601 tgaaaaaaaa ttggatgacg atgcaaacca tcatcaagac cagaagcagc acattggaga
      661 gaaatcgtac agaagcaatg ccaagggaac atcttttgta aagaactgta aattccatat
      721 gtcacatgag ccatttatct ttcatgaggt tgggaaagac tttttgtcca gcttgagatt
      781 actccaacaa gaggacattc acacttcagg gaagtcaaac tttgaaacta agcatgggat
      841 accccttcag ggtggaaaaa ctcattacat ctgtggagag tccacaatac cgtttagcaa
      901 caaacactca cttgtccttc accagagact tctccctaga gaaggacctt atgtatgcag
      961 tgattctggg aaattcacta gcaaaagtaa tagttttaat aatcatcagg gagttcgcac
     1021 tggaaaaaga ccttatcagt gtggacaatg tgatgaatca ttttggtata aggcccacct
     1081 cactgaacac cagagagttc acactggaga aagaccttat gagtgtggag aatgtgataa
     1141 atcttttagt cataagcaca gtcttgttga ccatcagcga gttcacactg gagaaagacc
     1201 ttatgaatgt gacgaatgtg ggaaatcttt tagccataag cgcagccttg ttcaccacca
     1261 gcgagttcac actggagaaa gaccttatca gtgtggagaa tgtgggaaat cgtttaatca
     1321 caagtgcaac ctcattcagc atcagcgagt tcacactgga gaaagacctt ttgagtgtac
     1381 ggcatgtggg aagttattta ggagcaactc ccacctaaag gaacaccaga gagttcacac
     1441 tggagaaaga ccctatgagt gtaaagaatg taggaaatca tttaggtaca agtcacacct
     1501 cactgaacac cagagagttc acactggaga aaggccatat gagtgtagag aatgtgggaa
     1561 atgttttcat caaaagggca gtctcattca acatcagcag atccactctg gagaaaggcc
     1621 acatgagtgt ggagaatgtg ggaaatgttt tcatcaaaag ggcagtctca ttcgacatca
     1681 gcagattcac tctggagaaa ggccacatga gtgtggagaa tgtggaaagt gttttcgtca
     1741 aaagggaaac ctcattaaac atcaacgagt tcacacggga gaaagacatc atgaatgttg
     1801 aaaatttggc agatctgttg gtaaaaagag caccctcatt caacattcgt gagatcacac
     1861 tggaaagcac ttatgagtat ggagaatgtg caaaatcatc tagccaaaag gttggcctca
     1921 ttcaacaata gcaagatcac actggggaaa ggctttctga gtgtagagaa tgtatgaaat
     1981 cctgtacata gaagttttgc ctcaccaaat accagaaggg tcacactgga gaaagaccct
     2041 atagttatgg ggaatttggg aaattaccta acaagaagtc ccacctcact gaacactact
     2101 gagttcacag ttgagaaagg ccatatgact gtaaggaatt tgtaaaatta tttagccaga
     2161 agagctgcat tactattcat cagataattt acaatggaga aaggccacat aataatttct
     2221 cacataataa atgtgagaaa tcatttccgt acagctctgc gctccatgtt cgtaagagtt
     2281 cacactggac aaagccttat gagagcagcg agtagaaaat cctttgtggg aaaactctgg
     2341 tttcattaaa cacaggagag ttcatgctag agaaaggcct caacagtgta gcaaatatgg
     2401 aaagacattc actagaagct ctgccctgca agttcacact agagaaagcc cttctcagtg
     2461 aagtaaattt ggaaaattga ttagtcaaac ctctatgctc cttcaaaatc agagttcaca
     2521 ctggatcaag gctttatggt gtgacaaata tggcacattc tttatctaaa tgtctaacat
     2581 attatgcaca gacaagctcc tgctgtggaa gtgccttttg agtgcagagc atttgcgagg
     2641 gcttcactct tctttcactg gataccagaa tgttgacagg agaaaaataa catagatgtg
     2701 tgggaatatt acttcttgtc cagtgtaact gtgggagaga gcccttatga ggacaccatc
     2761 aacctatatt gaatgtcata tgtccagtag ctgcataaat tccaggtata tgggagctgt
     2821 attgcatttc ttatcctgcg tatgtccttg ccagatttat ttcattctta ggtctctggc
     2881 aaaagccatt tcatctctac cacttggcag gtacctacag tgcatcactc atgcactcca
     2941 tcatattcca gaaaaaaagt tcaagttgtc tcccattcag cagtggtatt tttgagtagc
     3001 ctctgcactc gttcctttct catttctcta tgaagagtta ggccatggac ctgactcagt
     3061 tctggcctag agcagaagtg tccaatcttt tggctttcct ggtccacatt ggaagaagaa
     3121 ttgtcttgtg ccgcatatga aatacattaa cactaatgat agctgatgaa cttttttaaa
     3181 aaatcacaca aaaaccctca taatgtttta agaaagttta caaatttgtg ttgggctgca
     3241 ttcaaagctg tcctgagata catgcggccc acaagctgcg ggttggacca gcttggccta
     3301 gagaattttt ctgattactt gacaagatgg gctgtctttc ctaggaatct catgattgtc
     3361 atgattctta aaatggaatt ttccagcctc ttaactcacc aacccaagta caagctgcct
     3421 ctcattgttc tggtttctgc tatgatgaag tccttattta agcttccttc aatcttggga
     3481 attgtattga ctgtattgtg tgaattgtat actcactgca ttgtgtggct tagatacaac
     3541 atggttctgg taccatgaag gattctggta ccatgaaagt ttgttggggt tactaaactg
     3601 tgtgactctt agggaacagt atgaaggcag aatatagctc tgcatttgtg gcctagtttg
     3661 gatggctgcc taaggcctcc aaataaagac ttcagggctt tgtgatcttt atttttagat
     3721 gaaatagtgc aataatatgt gttttcataa atcaacctga gtaggggaca gttttagtga
     3781 cacactttgg tgcttctgag aacagcacaa aattattctc ttgtttataa tggatattgc
     3841 attctgctca gtactggtga gggaaatctg ttctcaagtc ctacagtgca ttcatgtgtc
     3901 ctgaagtcca gaattctgta ggatagtgtc ctacgttata agcctggaga aagaaatcat
     3961 aattctttaa tttttatttt tttagggaaa tgatgtcact ctgaaactca ggctggaata
     4021 cactggcatg gtcatacctc actgcggcct caaactcctg ggctcaagtg atcctcctgc
     4081 ctcagcctcc cgagtacctg agattagccc aggtaattta agaatttttt atagagatag
     4141 ggttttgcta ttttaccctg actgatgttc aactcctggc ctcaagtaat cctctagcat
     4201 acgcccttga aagcactagg attacaggtg tgagccacca tgcccagccc aaaaataatt
     4261 tttgtagaat tagcatttct aggtagtgaa gcagactgca acagaatagt tgggatatac
     4321 tttttttaaa aaggcatcca caatgattca gtcactatgt ctgtgatgga caagcaggta
     4381 cagaaatttt caggacctcc ataattatga atctagtgta gcttaggtca ttgtcagact
     4441 aaatctaaag gttttgtgga tttctgtagc ctatctgggc tgcataccaa aaagccatcc
     4501 ctgaattagt aggaggaaga ggatagggag aaaggaaatc tcttagtcca gtgatgtggc
     4561 ctttgcaacc agccagcatt ccaatttaat caggtggaaa tgatcttcct ggctcataag
     4621 tatttggtat cacacaggct aattgccccc cttagggcgt gatgagagtt aggagagtca
     4681 atgtaaaatc acataaccta tttgtcaaaa ataatgttaa atccagatag ttctttcaaa
     4741 ttaaattttt aaagctgtaa taagactggg catggtgact catgcctgtt atcccaacac
     4801 tttgggagtc cagggtggga gtattgcttg aggtaagaag tttgagacta gcctgggtcc
     4861 catagtaaga ccctgtctct taaaaaataa atactatctt tctctctggc ctctccatgc
     4921 tccagacaat cactgaatta caatatttgc ttaacagtag attaatgtca attttctgga
     4981 attttatatg actgatataa catgtttcct cttttcatac ctgagtactc tcctgagccc
     5041 tatttattta gatgttcttc ttttttcttt attattattt ttatttcaca tagcagggat
     5101 gcatattttg acattcatca atcatgatat atgagtagtt cattcttttt atcttagaat
     5161 atgacatgct atggaaatca ctgtatacga attcatctgc ttatggatat gttattgctt
     5221 cttatttttg tctgttagga ataaaactgc ttgttaagca ca
//
