LOCUS       NM_001142305            2069 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 771 (ZNF771), transcript variant
            2, mRNA.
ACCESSION   NM_001142305
VERSION     NM_001142305.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2069)
  AUTHORS   Yin,Y., Morgunova,E., Jolma,A., Kaasinen,E., Sahu,B.,
            Khund-Sayeed,S., Das,P.K., Kivioja,T., Dave,K., Zhong,F.,
            Nitta,K.R., Taipale,M., Popov,A., Ginno,P.A., Domcke,S., Yan,J.,
            Schubeler,D., Vinson,C. and Taipale,J.
  TITLE     Impact of cytosine methylation on DNA binding specificities of
            human transcription factors
  JOURNAL   Science 356 (6337) (2017)
   PUBMED   28473536
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK313930.1, BC011870.2 and AC116348.3.
            
            On May 17, 2019 this sequence version replaced NM_001142305.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC026192.2, SRR14038195.543679.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000319296.10/ ENSP00000323945.5
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1022              AK313930.1         313-1334
            1023-1250           BC011870.2         977-1204
            1251-2069           AC116348.3         102048-102866       c
FEATURES             Location/Qualifiers
     source          1..2069
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p11.2"
     gene            1..2069
                     /gene="ZNF771"
                     /gene_synonym="DSC43"
                     /note="zinc finger protein 771"
                     /db_xref="GeneID:51333"
                     /db_xref="HGNC:HGNC:29653"
     exon            1..59
                     /gene="ZNF771"
                     /gene_synonym="DSC43"
                     /inference="alignment:Splign:2.1.0"
     exon            60..209
                     /gene="ZNF771"
                     /gene_synonym="DSC43"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1022
                     /gene="ZNF771"
                     /gene_synonym="DSC43"
                     /note="mesenchymal stem cell protein DSC43"
                     /codon_start=1
                     /product="zinc finger protein 771"
                     /protein_id="NP_001135777.1"
                     /db_xref="CCDS:CCDS45460.1"
                     /db_xref="GeneID:51333"
                     /db_xref="HGNC:HGNC:29653"
                     /translation="MPGEQQAEEEEEEEMQEEMVLLVKGEEDEGEEKYEVVKLKIPMD
                     NKEVPGEAPAPSADPARPHACPDCGRAFARRSTLAKHARTHTGERPFGCTECGRRFSQ
                     KSALTKHGRTHTGERPYECPECDKRFSAASNLRQHRRRHTGEKPYACAHCGRRFAQSS
                     NYAQHLRVHTGEKPYACPDCGRAFGGSSCLARHRRTHTGERPYACADCGTRFAQSSAL
                     AKHRRVHTGEKPHRCAVCGRRFGHRSNLAEHARTHTGERPYPCAECGRRFRLSSHFIR
                     HRRAHMRRRLYICAGCGRDFKLPPGATAATATERCPECEGS"
     exon            210..2069
                     /gene="ZNF771"
                     /gene_synonym="DSC43"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1231..1236
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF771"
                     /gene_synonym="DSC43"
                     /note="hexamer: AATAAA"
     polyA_site      1255
                     /gene="ZNF771"
                     /gene_synonym="DSC43"
                     /note="major polyA site"
     regulatory      1904..1909
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF771"
                     /gene_synonym="DSC43"
                     /note="hexamer: AACAAA"
     polyA_site      1933
                     /gene="ZNF771"
                     /gene_synonym="DSC43"
ORIGIN      
        1 gagtgcccag ccgcccggcg cccaggcctg gggcaccgcg agtgccgaac cttcggctgg
       61 acaccaagat gcctggcgaa cagcaggcag aggaagagga ggaggaagag atgcaggagg
      121 agatggtgct gctggtgaag ggtgaggagg atgagggtga ggagaagtat gaggtggtga
      181 aactcaagat ccccatggac aacaaggagg tcccgggcga ggcgcccgcg ccgtccgccg
      241 acccggcgcg tccccacgcg tgccccgact gcggccgcgc cttcgcgcgc cgctccacgc
      301 tggcgaagca cgcgcgcacg cacacgggcg aacggccctt cgggtgcacc gagtgcgggc
      361 ggcgcttctc acagaagtcg gcgctgacca aacacggccg cacgcacacg ggcgagcggc
      421 cctacgagtg ccccgagtgc gacaaacgct tctcggccgc ctcgaacctg cggcagcacc
      481 ggcggcggca cacgggcgag aagccgtacg catgcgcgca ctgcggccgc cgcttcgcgc
      541 agagctccaa ctacgcacag cacctgcgcg tgcacacggg cgagaagccg tacgcgtgcc
      601 cggactgcgg acgcgccttt ggcggcagct cgtgcctggc gcgccaccga cgcacgcaca
      661 cgggcgagcg gccctacgct tgcgccgact gcggcacgcg cttcgctcag agctcggcgc
      721 tggccaagca ccggcgcgtg cacacgggcg agaagccgca ccgctgcgct gtgtgtggcc
      781 gtcgcttcgg ccaccgctcc aacctggcgg agcacgcgcg cacgcacaca ggcgagcggc
      841 cctacccctg cgccgagtgc ggccgccgct tccgcctaag ctcgcacttc attcgccacc
      901 gacgcgcgca catgcggcgc cgcctgtata tttgcgccgg ctgcggcagg gacttcaagc
      961 tgccccctgg cgccacggcc gccactgcca ccgagcgttg cccggagtgt gagggcagct
     1021 gagtcccgca gggctgcgga ggggcgcgct ggggcttcga cctggctgca ctaacccagg
     1081 ctcctcctcg ccccggcctc cgggtctggg aaattgaggg gacggcaggc ccggctgccc
     1141 tggaactggg agacagggag aatcccctgc cggggtccct ggaaacagtg cccaccccac
     1201 atcactacat tccctcggcc cgtgttagtg aataaagtat tatatcctca ccccacccgt
     1261 gcctgtgagt gaggtgggtg ggagaggaag aaagttgggg ttctccaggc tcaggtgcca
     1321 agtgagttgt caaggaacca aatggggatg taaacctaaa aggggttccc ggcacctcgg
     1381 tttgtgttgg ttggaggtga tcgcacactt ggcccttggt tacgtcctca taaccttaga
     1441 cctgaaaggg cccataaata tactatgttc acgatcagac acgcactgca ttcggcagag
     1501 ctccagtgag caaggcacga ccctcagatc tcagtctagt gaaggagaga aaactgtaat
     1561 aacactacgt taaaggtttt aactgctttg ttatgtaagc ttacccagcc cggcgcacag
     1621 tgactcacgc ctgtaatccc agcactttgg gagggcgagg ctagcagatc acttgaggtt
     1681 aggagttcga taccagcctg gccaacatgg tgaaacccgg tctctactaa aaatacaaaa
     1741 attaactggg tgtggtggcg ggcgcctgta atcccagcta ctgagggggc tgaggcatga
     1801 gaatcacttg aacctgggag acagaggttg caatgaaccg agatagtgcc attgcactcc
     1861 ggcctgggca acagaggaag actgcctcaa acaaacaaaa aacaacaaac caaaccaaac
     1921 caaaccaaaa aaatctcaaa gcgattggac ctagcagctc atgcctgtaa tctccagcac
     1981 tttgggaggc ggaggcagga ggatctcttg aagtcaagag tttgagatca gcctggagaa
     2041 caaagtgaga cccccatcta ttaaaaaaa
//
