LOCUS       NM_014106               5439 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 770 (ZNF770), mRNA.
ACCESSION   NM_014106 XM_090970
VERSION     NM_014106.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5439)
  AUTHORS   Wang,H., St Julien,K.R., Stevenson,D.K., Hoffmann,T.J., Witte,J.S.,
            Lazzeroni,L.C., Krasnow,M.A., Quaintance,C.C., Oehlert,J.W.,
            Jelliffe-Pawlowski,L.L., Gould,J.B., Shaw,G.M. and O'Brodovich,H.M.
  TITLE     A genome-wide association study (GWAS) for bronchopulmonary
            dysplasia
  JOURNAL   Pediatrics 132 (2), 290-297 (2013)
   PUBMED   23897914
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA331762.1, BC071603.1, AK131433.1, AK127201.1, AC114546.14 and
            AI031776.1.
            
            On Nov 22, 2018 this sequence version replaced NM_014106.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.259756.1,
                                           SRR1660809.43153.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2148093, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000356321.4/ ENSP00000348673.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-19                DA331762.1         10-28
            20-1424             BC071603.1         1-1405
            1425-2861           AK131433.1         306-1742
            2862-3746           AK127201.1         982-1866
            3747-5409           AC114546.14        28759-30421         c
            5410-5439           AI031776.1         6-35                c
FEATURES             Location/Qualifiers
     source          1..5439
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q14"
     gene            1..5439
                     /gene="ZNF770"
                     /gene_synonym="PRO1914"
                     /note="zinc finger protein 770"
                     /db_xref="GeneID:54989"
                     /db_xref="HGNC:HGNC:26061"
     exon            1..172
                     /gene="ZNF770"
                     /gene_synonym="PRO1914"
                     /inference="alignment:Splign:2.1.0"
     exon            173..289
                     /gene="ZNF770"
                     /gene_synonym="PRO1914"
                     /inference="alignment:Splign:2.1.0"
     exon            290..5439
                     /gene="ZNF770"
                     /gene_synonym="PRO1914"
                     /inference="alignment:Splign:2.1.0"
     CDS             346..2421
                     /gene="ZNF770"
                     /gene_synonym="PRO1914"
                     /codon_start=1
                     /product="zinc finger protein 770"
                     /protein_id="NP_054825.2"
                     /db_xref="CCDS:CCDS10042.1"
                     /db_xref="GeneID:54989"
                     /db_xref="HGNC:HGNC:26061"
                     /translation="MMAENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLAR
                     HYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLPFKCSICQRHFKNLKTFVKHQQL
                     HNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIH
                     ACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQC
                     CFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIG
                     ESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKT
                     IVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKH
                     GTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEF
                     FNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNIC
                     GKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGV
                     QKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL
                     YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQG
                     KVVALDSVM"
     regulatory      5419..5424
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF770"
                     /gene_synonym="PRO1914"
                     /note="hexamer: AATAAA"
     polyA_site      5439
                     /gene="ZNF770"
                     /gene_synonym="PRO1914"
                     /note="major polyA site"
ORIGIN      
        1 gttgccgcgc cggccctgcg gacgtgcgcg cgctgccttc gcggcacctg ggcctgaggt
       61 gcgtgcctcc cgggccctcg ccagctccag atgcgtgagg aggacttcag aaacccgact
      121 gagaagtgga gcgaccccca gggagggtcg gacctgcctc aataccgcca aggtctttca
      181 tttcttgttc gcttactttc gtgaaatcct cacatcgttt taatggtact agtcaagaca
      241 agaaaatcaa caggctttca gccttgaggc aacattggat attattgaga catctgtgga
      301 atttaagaac agtatggagc tcatcagagt atatcattga agaatatgat ggctgaaaac
      361 aatttaaaaa tgctaaagat tcaacagtgt gtggtagcca acaaactacc tagaaacagg
      421 ccatatgttt gcaatatttg ttttaagcac tttgaaacac catcaaaatt agctaggcac
      481 tatctcattc atactggtca aaagccattt gaatgtgatg tgtgtcataa aacctttaga
      541 caactagttc atctggagag gcatcaacta actcatagtc tgccttttaa atgtagtatt
      601 tgtcagcgtc actttaaaaa tctgaagaca tttgtgaagc accaacaact tcacaatgaa
      661 acctatcaga ataatgttaa acaggtcaga agattgctgg aggccaagca agaaaagtca
      721 atgtatggag tgtataatac ttttaccaca gaggaaagat gggcattaca cccgtgctct
      781 aagtctgatc ccatgtatag catgaaaaga agaaagaata ttcatgcatg tacaatctgt
      841 ggcaagatgt ttccatcaca gtcaaaactt gataggcatg tacttattca tactggtcag
      901 aggcctttta aatgtgtctt gtgtactaaa tcttttcgac agtcaactca cttaaaaatc
      961 caccaactta cacattcaga agaaagacct tttcaatgtt gtttttgtca aaaaggattt
     1021 aagattcaaa gcaaacttct gaagcataaa caaatccata ctaggaataa ggcttttcgg
     1081 gctcttttat taaagaagag gcgtacagaa tctcgccccc tgcctaataa gttaaatgca
     1141 aatcagggtg gttttgaaaa tggtgagatt ggtgaatctg aggagaataa tccacttgat
     1201 gtccactcaa tttatattgt cccttttcaa tgtccaaagt gtgaaaagtg ttttgaatca
     1261 gagcagattc tcaatgaaca cagctgtttt gctgctagaa gtggcaaaat tccaagcagg
     1321 ttcaaaagaa gctacaacta taaaaccatt gttaaaaaaa tcttggccaa gcttaagcgt
     1381 gctaggagta aaaaattaga taactttcaa tctgagaaaa aagtatttaa aaagagtttc
     1441 ttgagaaatt gtgatcttat ttctggtgag cagagctctg aacaaaccca gagaacattt
     1501 gtgggttctc ttggcaaaca tggaacatat aaaacaattg gcaatagaaa gaagaaaaca
     1561 ttgactttgc cattttcttg gcaaaatatg ggaaaaaatt tgaaaggcat ccttacgaca
     1621 gaaaacatat taagcattga taattcagtg aataagaaag acttgtcaat ctgtggttca
     1681 tcaggtgagg aattctttaa taactgtgag gtacttcagt gtggtttttc agttccaagg
     1741 gaaaacatac gtactagaca taagatatgt ccttgtgaca aatgtgagaa ggtatttcct
     1801 tctatatcca aactaaaaag acactattta attcatactg gacagaggcc ctttggctgt
     1861 aatatttgtg ggaaatcttt tagacagtca gctcacttaa aaagacatga acagactcat
     1921 aatgaaaaga gtccttatgc atctctttgc caagtagaat ttggaaactt caacaatctt
     1981 tctaatcatt caggtaataa tgttaactat aatgcttccc aacaatgtca ggctcctggt
     2041 gttcaaaaat acgaggtctc agagtcagat caaatgtcag gagttaaggc agagtcacag
     2101 gattttattc ctggtagcac cgggcaaccc tgtcttccta atgtactttt ggaatcagag
     2161 caaagcaatc ctttttgcag ttattcagag catcaggaga aaaatgatgt cttcctgtac
     2221 cgatgcagtg tttgtgctaa aagtttccga tctccatcta aactggaaag acactaccta
     2281 attcatgcag ggcagaaacc atttgaatgc tcagtttgtg gcaaaacatt cagacaggct
     2341 cctcactgga agagacatca gcttactcac tttaaagaac gaccacaagg gaaagtggtt
     2401 gccttagatt cggttatgta aattgtcgca accactaaca attgtggtct ctggtgatct
     2461 tatttttaaa gcctgtatta tttaaaatgc atttttattg aaaggcctgc attaaactga
     2521 atggtttcac aggcatttgc ttgtcctgca tagtaaggag gtagaataca tagaaaatta
     2581 atacaatgtt ttagaaacag ccaagttaat tttagaggca agaacatgat ttgatgctat
     2641 aaagtaggca ttttaatatt gtaaacatat actttggctg tattgaaaaa tataaatcca
     2701 tgatggctgt acaaataatt tagcctcatt cattttttaa aggaattatt ccttaagaca
     2761 tgccatctct ttttagatat actcaaaaga ctgagaggca aaacttggct tttagctgca
     2821 gcacatagcc ctgttatatt tgatttattt tacatttcat atgaaagcat aattttgtcc
     2881 acatgtgact caaattgcat tggtaatttt tttttttttt ttgtaagtta aaaaaactac
     2941 agagacacta aaggtgaaaa tggatgagac aattatagta ttattttcat tggtcttttt
     3001 ttttgagatg gagtctcact ctttcgccag gctagagtgc agtggcgcca tctaggctca
     3061 ctgcaacctc cgcatcccag attccagcga ttctcctgcc tcagcctcct gagtagctgg
     3121 gattacaggt gcctgccatc acgcctggct aatttttgta tttttagtag agacgggggt
     3181 tcaccaagtt ggccaggatg gtctcgatct cttgaccttg tgactcaccc gcatcggcct
     3241 cccaaagtgc tgggattaca ggcatgagcc accgcacccg acggtctttt caaagctatt
     3301 tatttttagg actatgtggt aatttcacct tcaggtgata aggatttttt ttttctccca
     3361 gctagtgcta tctttctcaa aataatttaa aagtaggcga gaggctagga tgtacctata
     3421 tttaccatgt ttacttacca ggaatatttt ctaagtgcca tagtcttttt cataatacgt
     3481 atgagtttta ccttttcaga ggaataattt caagtcattt atttgctcat taatgatagc
     3541 agtagtcata gacttaagac tattctagag atcttcatct ccataagact tttacattta
     3601 ttttagtaaa cttttctttc tatgcctctt taatggagtg gttctgttat ttaagcctgt
     3661 tctaagtttg atcaaatggc aatgactagg tctagtttta gtttttattt ttgcaggagt
     3721 ctattgctaa agaattttat tttgatgctt gttaaatttt tattttaatt aataaggtag
     3781 tcattcctgt agagggataa gatgcttgta gagttgtggg tatcattcca aatagaactg
     3841 ttatgatttg ggaaatattc tttactacaa aggacttatt tcataattac aaattttcct
     3901 tcatatttgc ctttgtttat aaaatcttca ggaatgacat tctctagcaa taaaaggaat
     3961 gaaccgttat gtttctaagc tgaaaagagg aacaggtggg taattatcct gccatactta
     4021 aatatagtgg aaaatcctct attgagaatg tggataaatg aacaattgta agttttgcat
     4081 cataaactga gaactttctt ttgacagggg ggaggcggga gggatagtag gtgggggtga
     4141 tctgcttgct tcttttacca caggtgattt ttaagtaact tgggtttaat ttacagagat
     4201 gaaacatgac agtctgagta aaatacccag tgatgtagaa gtgtgcctgt ttattatgta
     4261 gatacagaca tccagcaaaa acaggagaat cacatgcttt aaagaacact ttctcttagg
     4321 tttccttgag atatgttcct ccagtgcaag caagataatg gtttacagaa tttgctttac
     4381 acaaaacttg tcaagaactc atctgttaaa agcaaggaat aactagttta tattttccaa
     4441 taatgttcaa ggttttctcc ttaatatgtt tgaaattatt gattttggca tttttctaag
     4501 caatttatgt aattttattt gaagaaaatg ttttgtataa tgtttttccc agcctaaaca
     4561 gggagagtcc taacagtgtt gtgcttgtat gattctgaga ctttatttgc gtaagtgata
     4621 ctactatact ttatttttga cccatgcctt tttaagctgt ttcatattga aaggtggaat
     4681 attgtaaaaa ttttgtcaaa gatgtactgt agtgctattt gaagtacctg taacaaaaca
     4741 gttggccctc tgtatccatg tactctgcat ctgtggatta aaccaattgc agatcaaaaa
     4801 tattagaaaa aataaaaata atacaaataa aaatacagta taacagttat ttaaatagca
     4861 tttacattgc attaggtatt agtctaggga taaagtatac aggcggatgt gcgttggtta
     4921 tatacaaata tgtcatttta tgtaagggac ttgagtatac ttggattttt ggtatctgtg
     4981 ggttgggggg acggtccagg aaccaatacc ccatggatac caagggacaa ctgtacttat
     5041 ttacctttat tgtcattgca agcttcttat ggaaacttta taggaatgaa aatatacatg
     5101 ttaagaagat taaacattag atagtagatg gtttgttgca tgctagaact gttagtattg
     5161 ttgaatcaat tactttggtt tcatgaaaaa ataaacgata aatatcttta aagagaacta
     5221 gaagaatttt ttgtttgagt gattccaggc tgtagtatga tcatttactg aagtagtttg
     5281 attggctggc taacttagaa ttattgtttc ttgttttgta ctgcaatagg ggttataatt
     5341 gtaagataaa aatgtgtgtg tgtttaaggg aagtaggtgg tggttaaaat tcttggaaaa
     5401 ttttcagaat actttaaaaa taaagttcca agttacaca
//
