LOCUS       NM_001289951            3983 bp    mRNA    linear   PRI 06-APR-2024
DEFINITION  Homo sapiens zinc finger protein 761 (ZNF761), transcript variant
            2, mRNA.
ACCESSION   NM_001289951
VERSION     NM_001289951.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3983)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA237674.1, AC022137.6, DB232487.1 and BM977910.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001289951.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1, 2 and 3 all encode the same isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660805.64321.1,
                                           SRR6380201.95227.19 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000684525.1/ ENSP00000507666.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-45                DA237674.1         11-55
            46-46               AC022137.6         74747-74747         c
            47-588              DB232487.1         49-590
            589-3958            AC022137.6         62737-66106         c
            3959-3983           BM977910.1         18-42               c
FEATURES             Location/Qualifiers
     source          1..3983
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.42"
     gene            1..3983
                     /gene="ZNF761"
                     /gene_synonym="ZNF468"
                     /note="zinc finger protein 761"
                     /db_xref="GeneID:388561"
                     /db_xref="HGNC:HGNC:23179"
     exon            1..45
                     /gene="ZNF761"
                     /gene_synonym="ZNF468"
                     /inference="alignment:Splign:2.1.0"
     exon            46..156
                     /gene="ZNF761"
                     /gene_synonym="ZNF468"
                     /inference="alignment:Splign:2.1.0"
     exon            157..244
                     /gene="ZNF761"
                     /gene_synonym="ZNF468"
                     /inference="alignment:Splign:2.1.0"
     CDS             230..2470
                     /gene="ZNF761"
                     /gene_synonym="ZNF468"
                     /note="isoform a is encoded by transcript variant 2; zinc
                     finger protein 468"
                     /codon_start=1
                     /product="zinc finger protein 761 isoform a"
                     /protein_id="NP_001276880.1"
                     /db_xref="GeneID:388561"
                     /db_xref="HGNC:HGNC:23179"
                     /translation="MAFSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNL
                     VSLDISSKCTMKEFLSTAQGNREVFHAGTLQIHESHHNGDFCYQDVDKDIHDYEFQWQ
                     EDERNGHEAPMTKIKKLTGITERYDQSHARNKPIKDQLGSSFHSHLPEMHIFQTEEKI
                     DNQVVKSVHDASLVSTAQRISCRPKTHISNNHGNNFWNSSLLTQKQEVHMREKSFQCN
                     ESGKAFNYSSLLRKHQIIHLADKYKCDVCGKLFNQKRNLACHRRCHTGENPYKCNECG
                     KTFSQTSSLTCHRRLHTGEKPYKCEECDKAFHFKSILERHRIIHTEEKPYKCNECGKT
                     FRQKSILTRHHRLHTGEKPYKCNECGKTFSHKSSLTCHHRLHTGEKPYKCNECGKTFS
                     HKSSLTCHRRLHTGEKPYKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRT
                     SSLTCHRRRHTGEQPYKCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSY
                     LTCHHRLHTGEKAYKCNECGKTFSWKSSLTCHRRLHSGEKPYKCKECGKTFNQQLTLK
                     RHRRLHSGENPYKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLTCH
                     RRLHTGEKPYKCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSYFICHHR
                     LHTGEKPYKCNECGKNFSQKSSLICHHRLHTGEKPYKCNECGKTFSQKSNLTCHRRLH
                     TGEKQV"
     exon            245..371
                     /gene="ZNF761"
                     /gene_synonym="ZNF468"
                     /inference="alignment:Splign:2.1.0"
     exon            372..3983
                     /gene="ZNF761"
                     /gene_synonym="ZNF468"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3957..3962
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF761"
                     /gene_synonym="ZNF468"
                     /note="hexamer: AATATA"
     polyA_site      3983
                     /gene="ZNF761"
                     /gene_synonym="ZNF468"
                     /note="major polyA site"
ORIGIN      
        1 agaccaggaa gcggatagcg tggagtgacg gtgccaccgc ggcgcagtat tgcccgggct
       61 gtgagtgcag tctcatgatc ttgggtcact gcaacctctg tttcctgggt tcaagtgatt
      121 cttgtgcctc agcatcccac gtagctgaga ttacaggatt gacttctaaa gactcttggt
      181 acgtgaggaa gaaacccgga agaggaagag gagagcaaag gagtcaggga tggctttttc
      241 tcagggtcta ttgacattca gggatgtggc catagaattc tctcaggagg agtggaaatg
      301 cctggaccct gctcagagga ctctatacag ggacgtgatg ctggagaatt ataggaacct
      361 ggtctccctg gatatctctt ccaaatgcac gatgaaggag ttcttgtcaa cagcgcaagg
      421 caacagagaa gtgttccatg cagggacatt gcaaatacat gaaagtcatc acaatggaga
      481 tttttgctac caggatgttg ataaagatat tcatgactat gaatttcaat ggcaagaaga
      541 tgaaagaaat ggccatgaag cacccatgac aaaaatcaaa aagttgacag gtattacaga
      601 acgatatgat caaagtcatg ctagaaacaa gcctattaaa gatcagcttg gatcaagctt
      661 tcattcgcat ctgcctgaaa tgcacatatt tcagaccgaa gagaaaattg ataatcaagt
      721 tgtgaagtct gtccacgatg cttccttggt ttcaacagcc caaagaattt cttgtaggcc
      781 caaaacccat atatctaata accatgggaa taatttctgg aattcttcat tactcacaca
      841 aaaacaggaa gtacacatga gagaaaaatc tttccaatgt aatgagagtg gcaaagcctt
      901 taattacagc tcactcttaa ggaaacatca gataatccat ttagcagaca aatataaatg
      961 tgatgtatgt ggcaagctct ttaatcagaa gcgaaaccta gcatgccatc gtagatgtca
     1021 cactggtgag aatccttaca agtgtaatga gtgtggcaag accttcagtc agacgtcatc
     1081 ccttacatgc catcgtagac ttcatactgg agagaaacct tacaaatgtg aagaatgtga
     1141 caaagctttc catttcaaat caatacttga aagacatagg ataattcata ctgaagagaa
     1201 accatataag tgtaatgagt gtggcaagac ctttaggcag aagtcaatcc ttacacgcca
     1261 tcatcgactt catactggag agaaacctta caagtgtaat gagtgtggca agacctttag
     1321 tcacaagtca tcccttacat gccatcatag acttcatact ggagagaaac cctacaaatg
     1381 taatgagtgt ggcaagacct ttagtcacaa gtcatccctt acatgccatc gtagacttca
     1441 tactggagag aaaccttaca aatgtgaaga atgtgacaaa gcttacagtt tcagatcaaa
     1501 ttttgaaata catcggaaaa ttcatactga agacaatgct tacaagtgta atgagtgtgg
     1561 aaagaccttt agccggacat catcccttac atgccatcgt agacgtcata ctggagagca
     1621 accttacaaa tgtgaagaat gtgacaaagc tttccgtttc aaatcaaacc ttgaaagaca
     1681 taggagaatt catactggag agaaaccata caagtgtaat gagtgtggca agacctttag
     1741 tcggaagtca tacctcacat gccatcatag acttcatact ggagagaaag cttacaagtg
     1801 taatgagtgc ggcaagacct ttagttggaa gtcatccctt acctgccatc gtagacttca
     1861 ttctggagag aaaccttaca agtgtaagga gtgtggcaag accttcaatc agcagttaac
     1921 ccttaaacgc catcgtagac ttcatagtgg agagaaccct tacaaatgtg aagatagtga
     1981 caaagcttac agtttcaaat caaaccttga aatacatcag aaaattcata ctgaagagaa
     2041 tccttacaag tgtaatgagt gtggcaagac cttcagtcgg acgtcatccc ttacatgcca
     2101 tcgtagactt cataccggag agaaacctta caaatgtgaa gaatgtgaca aagctttccg
     2161 tgtgaaatca aaccttgaag gacataggag aattcatact ggagagaaac cttacaagtg
     2221 taatgagtgt ggcaagacct ttagtcggaa gtcatatttt atatgccatc atagacttca
     2281 tactggagag aaaccttata agtgtaatga gtgtggcaag aactttagtc agaagtcatc
     2341 ccttatatgc caccatagac ttcatactgg agagaaacct tacaagtgta atgagtgtgg
     2401 caagaccttt agtcagaagt caaaccttac atgccatcgt agacttcata ctggagaaaa
     2461 acaagtgtaa tgaatgtggt gaggttttta atcaacaagc acaccttgca ggtcatcata
     2521 gaattcatac tggggagaaa ccttagaaat gtgaagcatg tgataaagtt tacagtggca
     2581 aatcaagcct cagaagacag gagaattcat actggagaga aagcttataa atgtgaagaa
     2641 tgtcacaaag tttacagtcg cacatcaaac cgtgaaagac aggagaattc atactggaga
     2701 gaaaccataa aaatgtaaga gtttgtgaca aggcttttgg gcatgattcg cacctggcac
     2761 aacatgctag aattcacact ggagagaaac cttaccagtg taatgagtgt ggcaaagcct
     2821 ttagtaggca gtcaacactt gtttaccgtc aggcaatcca tggtgtaggg aaactttact
     2881 aaggtaatga ttgtcacaaa gtcttcagta atgctacaac cattgtgaat cactggagaa
     2941 tccataagga agagagatca tactagggta ataaatgtgg cagatttttc agacattgtt
     3001 cataccttgc agttcatcgg tgaactcaac gctggagaga aaccttacaa atgtcatgac
     3061 tgtggcaagg tcttcagtca agcttcatcc tatgcaaaac ataggagaat tcatacagga
     3121 gagaaacctc acatgtgtga tgatagtggc aaagccttca cttcacacct catgagacat
     3181 cagagaatgc atactggaca gaaatcttac aaatgtcatc aatgtgccaa ggtcttcagt
     3241 ctgagttcac tccttgcaga atatgagaaa attcattttg gaggtagttg gtccatatgc
     3301 aatgagtaga gcaaaccatc aagcattaat tgacattagg gtcaattcag cattgacttg
     3361 agtttgtatt gacttaacat tgagttcaag cattaattga cattagtgtt tatgttaaga
     3421 ggattgggcc aggcacatca gcttacacct gtaatctgag cgctttggga ggccaaggtg
     3481 ggtagatcac ttgaggtcag gagtttgaga tcagcctggc caacagacgt gagccatttt
     3541 cccagcctgt tttttgtttc tttaaaaaaa ctgataggga tttttatgga tatcatgttg
     3601 aatctaaatc acattgggtt attatataat catttcacaa tattaatttt tccaagctat
     3661 caatatgggt tgtagctcaa tgtttttaat cattttgatc aatgtttgta gatttcaagg
     3721 tacaaacttc tgacctttgt acgtttattt ctaagtattt ctttaagttc tccagcaaat
     3781 ggaagtgttt taaaattttc ttttaaaatt gtttattgtt aaagtatgga aattcaacta
     3841 atttttggtg ctgatactgt attgtgcaaa tccactgact atgttactta gttccagtag
     3901 tattttggtt ggctctttgt gattttctac acagaagatt atgtcatcta caaacaaata
     3961 taattttact tcttactttc tga
//
