LOCUS       NM_001159524            1239 bp    mRNA    linear   PRI 03-APR-2024
DEFINITION  Homo sapiens zinc finger protein 735 (ZNF735), mRNA.
ACCESSION   NM_001159524 XM_001719618 XM_001719651 XM_002344353 XM_002346880
VERSION     NM_001159524.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1239)
  AUTHORS   Imbeault,M., Helleboid,P.Y. and Trono,D.
  TITLE     KRAB zinc-finger proteins contribute to the evolution of gene
            regulatory networks
  JOURNAL   Nature 543 (7646), 550-554 (2017)
   PUBMED   28273063
REFERENCE   2  (bases 1 to 1239)
  AUTHORS   Wang,J., Wang,J. and Tian,C.Y.
  TITLE     Evolution of KRAB-containing zinc finger proteins and their roles
            in species evolution
  JOURNAL   Yi Chuan 38 (11), 971-978 (2016)
   PUBMED   27867147
  REMARK    Review article
REFERENCE   3  (bases 1 to 1239)
  AUTHORS   Wang,W., Cai,J., Lin,Y., Liu,Z., Ren,Q., Hu,L., Huang,Z., Guo,M.
            and Li,W.
  TITLE     Zinc fingers function cooperatively with KRAB domain for nuclear
            localization of KRAB-containing zinc finger proteins
  JOURNAL   PLoS One 9 (3), e92155 (2014)
   PUBMED   24647005
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1239)
  AUTHORS   Razin,S.V., Borunova,V.V., Maksimenko,O.G. and Kantidze,O.L.
  TITLE     Cys2His2 zinc finger protein family: classification, functions, and
            major members
  JOURNAL   Biochemistry (Mosc) 77 (3), 217-226 (2012)
   PUBMED   22803940
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC104094.4 and AC073270.6.
            
            On or before Jul 18, 2009 this sequence version replaced
            XM_001719618.1, XM_001719651.1, XM_002344353.1, XM_002346880.1.
            
            Summary: This gene encodes a kruppel-associated box-containing zinc
            finger protein (KRAB-ZFP). The encoded protein contains an
            N-terminal kruppel-associated box (KRAB) domain and nine C-terminal
            C2H2-type zinc finger domains. The KRAB-ZFPs represent the largest
            family of mammalian transcriptional repressors, which function
            through the recruitment of the nuclear co-factor KRAB-Associated
            Protein 1 (KAP1), to engage histone modifiers and induce
            heterochromatin formation. [provided by RefSeq, Jul 2017].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000429565.5/ ENSP00000485547.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-39                AC104094.4         23892-23930
            40-166              AC104094.4         29781-29907
            167-262             AC104094.4         30702-30797
            263-697             AC104094.4         36003-36437
            698-1239            AC073270.6         1-542
FEATURES             Location/Qualifiers
     source          1..1239
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q11.21"
     gene            1..1239
                     /gene="ZNF735"
                     /gene_synonym="ZNF735P"
                     /note="zinc finger protein 735"
                     /db_xref="GeneID:730291"
                     /db_xref="HGNC:HGNC:32466"
     CDS             1..1239
                     /gene="ZNF735"
                     /gene_synonym="ZNF735P"
                     /note="zinc finger protein 735 pseudogene"
                     /codon_start=1
                     /product="putative zinc finger protein 735"
                     /protein_id="NP_001152996.1"
                     /db_xref="CCDS:CCDS78236.1"
                     /db_xref="GeneID:730291"
                     /db_xref="HGNC:HGNC:32466"
                     /translation="MAKRPGPPGSREMGLLTFRDIAIEFSLAEWQCLDHAQQNLYRDV
                     MLENYRNLFSLGMTVSKPDLIACLEQNKEPQNIKRNEMAAKHPVTCSHFNQDLQPEQS
                     IKDSLQKVIPRTYGKCGHENLQLKKCCKRVDECEVHKGGYNDLNQCLSNTQNKIFQTH
                     KCVKVFSKFSNSNRHNARYTGKKHLKCKKYGKSFCMFSHLNQHQIIHTKEKSYKCEEC
                     GKSFNHSSSGTTHKRILTGEKPYRCEECGKAFRWPSNLTRHKRIHTGEKPYACEECGQ
                     AFRRSSTLTNHKRIHTGERPYKCEECGKAFSVSSALIYHKRIHTGEKPYTCEECGKAF
                     NCSSTLKTHKIIHTGEKPYTCEECGRTFNCSSTVKAHKRIHTGEKPYKCEECDKAFKW
                     HSSLAKHKIIHTGEKPYKCK"
     exon            1..39
                     /gene="ZNF735"
                     /gene_synonym="ZNF735P"
                     /inference="alignment:Splign:2.1.0"
     exon            40..166
                     /gene="ZNF735"
                     /gene_synonym="ZNF735P"
                     /inference="alignment:Splign:2.1.0"
     exon            167..262
                     /gene="ZNF735"
                     /gene_synonym="ZNF735P"
                     /inference="alignment:Splign:2.1.0"
     exon            263..1239
                     /gene="ZNF735"
                     /gene_synonym="ZNF735P"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggctaaaa gaccgggacc ccctggaagc cgagaaatgg gactgttgac attcagagac
       61 atagctatag aattctctct ggcggagtgg caatgcctgg atcatgctca gcagaattta
      121 tatagagatg tgatgttaga gaactacaga aacctgttct ccctgggtat gactgtctct
      181 aagccagact tgatcgcctg tctggagcaa aataaagagc cccagaatat aaagagaaat
      241 gagatggcag ccaaacaccc agttacatgt tctcatttca accaagacct tcagccagag
      301 cagagcataa aagattcact ccaaaaagta ataccaagaa catatggaaa atgtggacat
      361 gagaatttac aattaaaaaa atgttgtaaa agagtagatg agtgtgaggt gcacaaagga
      421 ggttataatg accttaacca atgtttgtca aatacccaaa acaaaatatt tcagactcat
      481 aaatgtgtca aagtcttcag taaattttca aattccaata gacacaatgc aagatatact
      541 ggaaagaaac atttgaaatg taaaaaatat ggcaaatcat tttgcatgtt ttcacaccta
      601 aatcaacatc agataattca tactaaggag aagtcctaca aatgtgaaga atgtggcaaa
      661 tcctttaacc actcctcaag cggtactaca cataaaagaa ttcttactgg agagaaaccc
      721 tacagatgtg aggaatgtgg caaagccttt aggtggccct caaaccttac tagacataag
      781 agaattcaca ctggagagaa accctacgca tgtgaagaat gtggccaagc ctttaggcgc
      841 tcctcaacac ttactaacca caagagaatt catactggag agagacccta caaatgtgaa
      901 gaatgtggca aagcctttag cgtatcctca gccctcattt accacaagag aattcatact
      961 ggagagaaac cctacacatg tgaagaatgt ggcaaagcct ttaactgctc ctcgactctt
     1021 aagacacata agataattca tactggagag aaaccctaca catgtgaaga atgtggcaga
     1081 acctttaact gctcctcaac tgtaaaggca cataagagaa ttcatactgg agagaaacca
     1141 tacaaatgtg aagaatgtga caaagctttt aagtggcatt caagtcttgc taaacataag
     1201 ataattcaca ctggagagaa accctacaaa tgtaaataa
//
