LOCUS       NM_001267716            2600 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 728 (ZNF728), mRNA.
ACCESSION   NM_001267716 XM_001720936 XM_001726961
VERSION     NM_001267716.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2600)
  AUTHORS   Wang,H., St Julien,K.R., Stevenson,D.K., Hoffmann,T.J., Witte,J.S.,
            Lazzeroni,L.C., Krasnow,M.A., Quaintance,C.C., Oehlert,J.W.,
            Jelliffe-Pawlowski,L.L., Gould,J.B., Shaw,G.M. and O'Brodovich,H.M.
  TITLE     A genome-wide association study (GWAS) for bronchopulmonary
            dysplasia
  JOURNAL   Pediatrics 132 (2), 290-297 (2013)
   PUBMED   23897914
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB076533.1, AC011502.7 and AC022145.8.
            
            On May 17, 2019 this sequence version replaced NM_001267716.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            transcript and genomic sequence to make the sequence consistent
            with the reference genome assembly. The genomic coordinates used
            for the transcript record were based on alignments and RNAseq data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.247252.1,
                                           SRR1660803.8227.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2144120
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000594710.2/ ENSP00000471593.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-549               DB076533.1         12-560
            550-2165            AC011502.7         14626-16241         c
            2166-2600           AC022145.8         174560-174994       c
FEATURES             Location/Qualifiers
     source          1..2600
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p12"
     gene            1..2600
                     /gene="ZNF728"
                     /note="zinc finger protein 728"
                     /db_xref="GeneID:388523"
                     /db_xref="HGNC:HGNC:32463"
     exon            1..149
                     /gene="ZNF728"
                     /inference="alignment:Splign:2.1.0"
     CDS             147..2015
                     /gene="ZNF728"
                     /codon_start=1
                     /product="zinc finger protein 728"
                     /protein_id="NP_001254645.1"
                     /db_xref="CCDS:CCDS59370.1"
                     /db_xref="GeneID:388523"
                     /db_xref="HGNC:HGNC:32463"
                     /translation="MGSLTFRDVAIQFSLEEWQCLDTAQQNLYRNVMLENYRNLVFLG
                     IAAPKPDLIIFLEQGKEPWNMKRHELVKEPPVICSHFAQDLWPEQGREDSFQKVILRR
                     YEKCGHENLQLKIGCTNVDECKVHKKGYNKLNQSLTTTQSKVFQCGKYANIFHKCSNS
                     KRHKIRHTGKKLLKCKEYVRSFCMLSHLSQHKRIYTRENSYKSEEHGKAFNWSSALTY
                     KRIHTGEKPCKCEECGKAFSKFSILTKHKVIHTGEKHYKCEECGKAFTRSSSLIEHKR
                     SHAGEKPYKCEECGKAFSKASTLTAHKTIHAGEKPYKCEECGKAFNRSSNLMEHKRIH
                     TGEKPCKCEECGKAFGNFSTLTKHKVIHTGEKPYKCEECGKAFSWPSSLTEHKRIHAG
                     DKPYKCEECGKTFKWSSTLTKHKIIHTGEKPYKCEECGKAFTTFSSLTKHKVIHTGEK
                     HYKCEECGKVFSWSSSLTTHKAIHAGEKLYKCEECGKAFKWSSNLMEHKRIHTGEKPY
                     KCEECGKAFSKVANLTKHKVIHTGEKQYKCEECGKAFIWSSRLSEHKRIHTGEKPYKC
                     EECGKAFSWVSVLNKHKKIHAGKKFYKCEECGKDFNQSSHLTTHKRIHTGGKTLQM"
     exon            150..276
                     /gene="ZNF728"
                     /inference="alignment:Splign:2.1.0"
     exon            277..372
                     /gene="ZNF728"
                     /inference="alignment:Splign:2.1.0"
     exon            373..2600
                     /gene="ZNF728"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2510..2515
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF728"
                     /note="hexamer: AATAAA"
     polyA_site      2535
                     /gene="ZNF728"
                     /note="major polyA site"
ORIGIN      
        1 gttggctctc gctgcacgcg gaggtcaagg tgtcgtcctt actgctgtgt gtcgtccgct
       61 cctaaaggcc cagcttctat ggccctgtga cctgcaggta ttgggagatt cacaactaag
      121 tcgccaggac ccccggaagc ctagaaatgg gatcgttgac atttcgggat gtggccatac
      181 aattctctct ggaggagtgg caatgcctgg acactgcaca gcagaattta tataggaatg
      241 tgatgttaga gaactacaga aacctggtct tcctgggtat tgctgcccct aagccagacc
      301 tgatcatttt tctggagcaa ggaaaagagc cctggaatat gaagagacat gagctggtga
      361 aagaaccgcc agttatatgt tctcattttg ctcaagacct ttggccagag cagggcagag
      421 aagattcttt ccaaaaagtg atattgagaa gatatgaaaa atgtggacat gagaatttac
      481 agttaaaaat tggttgtacc aatgtggatg agtgtaaggt gcacaaaaaa ggttataata
      541 agcttaacca gagtttgaca actacacaaa gcaaagtatt tcaatgtggc aaatatgcaa
      601 acatctttca taaatgttca aattcaaaaa gacataagat aaggcatact ggaaagaaac
      661 ttttgaaatg taaagaatat gtcagatcat tttgcatgct ttcacaccta tctcaacata
      721 aaagaattta tactagagag aattcctaca aaagtgaaga acatggcaaa gcctttaact
      781 ggtcctcagc ccttacttat aagagaattc atactggaga gaaaccctgc aaatgtgaag
      841 aatgtggcaa agcctttagt aagttctcaa tccttactaa gcataaggta attcatactg
      901 gagagaaaca ttacaaatgt gaagaatgtg gcaaagcctt cacccggtcc tcaagcctta
      961 ttgaacataa gagaagtcat gctggagaga aaccctacaa atgtgaagaa tgtggcaaag
     1021 cctttagtaa ggcctcaacc cttactgcac ataagacaat tcatgctgga gagaaaccct
     1081 acaaatgtga agaatgtggc aaagctttca accggtcctc aaaccttatg gaacataaga
     1141 gaattcatac tggagagaag ccctgcaaat gtgaagaatg tggcaaagcc tttggtaact
     1201 tctcaaccct tactaaacat aaggtaattc atactggaga gaaaccctac aaatgtgaag
     1261 aatgtggcaa agccttcagc tggccctcaa gccttactga acacaagaga attcatgctg
     1321 gagacaaacc ttacaaatgt gaagaatgtg gcaaaacctt taagtggtcc tcaacactta
     1381 ctaaacataa gataattcat actggagaga aaccctacaa atgtgaagaa tgtggcaaag
     1441 cctttactac attttcgagc cttactaaac ataaagtaat tcatactgga gagaaacact
     1501 acaaatgtga agaatgtggc aaagtcttca gctggtcctc aagccttact acacataagg
     1561 caattcatgc tggagagaaa ctctacaaat gtgaagaatg tggcaaagcc tttaagtggt
     1621 cctcaaacct tatggaacat aagagaattc atactggaga gaaaccctac aaatgtgaag
     1681 aatgtggcaa agccttcagt aaggttgcaa accttactaa acataaggta attcatactg
     1741 gagagaaaca atacaaatgt gaagaatgtg gcaaagcctt catctggtcc tcaagactta
     1801 gtgaacataa gagaattcat actggagaga aaccctacaa atgtgaagaa tgtggcaaag
     1861 cctttagctg ggtctcagtc cttaacaaac ataagaaaat tcatgctgga aagaaattct
     1921 acaaatgtga agaatgtggt aaagacttca accaatcctc acaccttact actcataaga
     1981 gaattcatac tggaggaaaa accctacaaa tgtgaaaaat gtggcaaagc tttcaattag
     2041 ttcttaaccc ttactgaaca taagggtatt tatacaggag ggaaacccta caaatgtgaa
     2101 gaatgtggca aattttttaa ctgttcctca atccttacta aacataaggt aattcatact
     2161 ggagggaatt cctacaattg tgtggaatgt ggcaaagcct ttaatcagtc cttaaggctt
     2221 actacgtaca agacaactca tactggagag aaaccataca cgtgtgaaga atgtgggaaa
     2281 gcctctaaca gatcctcaat tcttaacaga cataagctaa ttcatactag agagaaactg
     2341 caaacctgaa agatgtgaca aggcttttgg caacacctga aacttttctg aatataaaag
     2401 aaatcatact ggtgagaaat cctagaaatg tgaagaatgt gacaaagcct ttaaatggct
     2461 gtcacacttg attgtaggta agatatctca tactggagaa aactactaga ataaacaatg
     2521 tggcaaaaca tttaaccaat gctcatgcct aattgcaaag gaaagcattt acactagcct
     2581 gggcaacaga gggagactgt
//
