LOCUS       NM_133474               4673 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 721 (ZNF721), mRNA.
ACCESSION   NM_133474 XM_496681
VERSION     NM_133474.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4673)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 4673)
  AUTHORS   Kimura,K., Wakamatsu,A., Suzuki,Y., Ota,T., Nishikawa,T.,
            Yamashita,R., Yamamoto,J., Sekine,M., Tsuritani,K., Wakaguri,H.,
            Ishii,S., Sugiyama,T., Saito,K., Isono,Y., Irie,R., Kushida,N.,
            Yoneyama,T., Otsuka,R., Kanda,K., Yokoi,T., Kondo,H., Wagatsuma,M.,
            Murakawa,K., Ishida,S., Ishibashi,T., Takahashi-Fujii,A.,
            Tanase,T., Nagai,K., Kikuchi,H., Nakai,K., Isogai,T. and Sugano,S.
  TITLE     Diversification of transcriptional modulation: large-scale
            identification and characterization of putative alternative
            promoters of human genes
  JOURNAL   Genome Res 16 (1), 55-65 (2006)
   PUBMED   16344560
REFERENCE   3  (bases 1 to 4673)
  AUTHORS   Ota,T., Suzuki,Y., Nishikawa,T., Otsuki,T., Sugiyama,T., Irie,R.,
            Wakamatsu,A., Hayashi,K., Sato,H., Nagai,K., Kimura,K., Makita,H.,
            Sekine,M., Obayashi,M., Nishi,T., Shibahara,T., Tanaka,T.,
            Ishii,S., Yamamoto,J., Saito,K., Kawai,Y., Isono,Y., Nakamura,Y.,
            Nagahari,K., Murakami,K., Yasuda,T., Iwayanagi,T., Wagatsuma,M.,
            Shiratori,A., Sudo,H., Hosoiri,T., Kaku,Y., Kodaira,H., Kondo,H.,
            Sugawara,M., Takahashi,M., Kanda,K., Yokoi,T., Furuya,T.,
            Kikkawa,E., Omura,Y., Abe,K., Kamihara,K., Katsuta,N., Sato,K.,
            Tanikawa,M., Yamazaki,M., Ninomiya,K., Ishibashi,T., Yamashita,H.,
            Murakawa,K., Fujimori,K., Tanai,H., Kimata,M., Watanabe,M.,
            Hiraoka,S., Chiba,Y., Ishida,S., Ono,Y., Takiguchi,S., Watanabe,S.,
            Yosida,M., Hotuta,T., Kusano,J., Kanehori,K., Takahashi-Fujii,A.,
            Hara,H., Tanase,T.O., Nomura,Y., Togiya,S., Komai,F., Hara,R.,
            Takeuchi,K., Arita,M., Imose,N., Musashino,K., Yuuki,H., Oshima,A.,
            Sasaki,N., Aotsuka,S., Yoshikawa,Y., Matsunawa,H., Ichihara,T.,
            Shiohata,N., Sano,S., Moriya,S., Momiyama,H., Satoh,N., Takami,S.,
            Terashima,Y., Suzuki,O., Nakagawa,S., Senoh,A., Mizoguchi,H.,
            Goto,Y., Shimizu,F., Wakebe,H., Hishigaki,H., Watanabe,T.,
            Sugiyama,A., Takemoto,M., Kawakami,B., Yamazaki,M., Watanabe,K.,
            Kumagai,A., Itakura,S., Fukuzumi,Y., Fujimori,Y., Komiyama,M.,
            Tashiro,H., Tanigami,A., Fujiwara,T., Ono,T., Yamada,K., Fujii,Y.,
            Ozaki,K., Hirao,M., Ohmori,Y., Kawabata,A., Hikiji,T., Kobatake,N.,
            Inagaki,H., Ikema,Y., Okamoto,S., Okitani,R., Kawakami,T.,
            Noguchi,S., Itoh,T., Shigeta,K., Senba,T., Matsumura,K.,
            Nakajima,Y., Mizuno,T., Morinaga,M., Sasaki,M., Togashi,T.,
            Oyama,M., Hata,H., Watanabe,M., Komatsu,T., Mizushima-Sugano,J.,
            Satoh,T., Shirai,Y., Takahashi,Y., Nakagawa,K., Okumura,K.,
            Nagase,T., Nomura,N., Kikuchi,H., Masuho,Y., Yamashita,R.,
            Nakai,K., Yada,T., Nakamura,Y., Ohara,O., Isogai,T. and Sugano,S.
  TITLE     Complete sequencing and characterization of 21,243 full-length
            human cDNAs
  JOURNAL   Nat Genet 36 (1), 40-45 (2004)
   PUBMED   14702039
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            HY075884.1, DA309597.1, AC092574.2 and AI223001.1.
            
            On Nov 23, 2018 this sequence version replaced NM_133474.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.136791.1, DA309597.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2152798 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000511833.3/ ENSP00000428878.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 HY075884.1         16-17
            3-599               DA309597.1         1-597
            600-4286            AC092574.2         69277-72963         c
            4287-4673           AI223001.1         9-395               c
FEATURES             Location/Qualifiers
     source          1..4673
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p16.3"
     gene            1..4673
                     /gene="ZNF721"
                     /note="zinc finger protein 721"
                     /db_xref="GeneID:170960"
                     /db_xref="HGNC:HGNC:29425"
     exon            1..101
                     /gene="ZNF721"
                     /inference="alignment:Splign:2.1.0"
     exon            102..228
                     /gene="ZNF721"
                     /inference="alignment:Splign:2.1.0"
     CDS             195..2966
                     /gene="ZNF721"
                     /codon_start=1
                     /product="zinc finger protein 721"
                     /protein_id="NP_597731.2"
                     /db_xref="CCDS:CCDS46991.1"
                     /db_xref="GeneID:170960"
                     /db_xref="HGNC:HGNC:29425"
                     /translation="MLENYRNLVSLAMCSHFTQDFLPVQGIEDSFHKLILRRYEKCGH
                     DNLQLRKGCKSMNVCKVQKGVYNGINKCLSNTQSKIFQCNARVKVFSKFANSNKDKTR
                     HTGEKHFKCNECGKSFQKFSDLTQHKGIHAGEKPYTCEERGKDFGWYTDLNQHKKIHT
                     GEKPYKCEECGKAFNRSTNLTAHKRIHNREKAYTGEDRDRAFGWSTNLNEYKKIHTGD
                     KPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKCKECGKVISSSSSFAKHKRIHTGEKP
                     FKCLECGKAFNISTTLTKHRRIHTGEKPYTCEVCGKAFRQSANLYVHRRIHTGEKPYT
                     CGECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQHKKIHTGEKPYKCE
                     ECGKAFNSSTNLTAHKRIHTREKPYTCEDRGRAFGLSTNLNEYKKIHTGDKPYKCKEC
                     GKAFIHSLHLNKHEKIHTGKKPYKCKQCGKVITSSSSFAKHKRIHTGEKPFECLECGK
                     AFTSSTTLTKHRRIHTGEKPYTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTF
                     RQSANLYVHRRIHTGEKPYKCEECGKAFGRYTDLNQHKKIHTGEKLYKCEECGKDFVW
                     YTDLNQQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCEECGKAFGWSI
                     ALNQHKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTREKPYKCEDRGRSFGWSTNL
                     NEYKKIHTGDKLYKCKECGKVFKQSSHLNRHEKIHTGKKPYKCKECGKVITSSSSFAK
                     HKRIHTGEKPFKCLECGKAFTSSTTLTKHRRIHTGEKPYTCEECGKAFRQSAILYVHR
                     RIHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQSANLYAHKKI
                     HTGDKTIQV"
     exon            229..4673
                     /gene="ZNF721"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4649..4654
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF721"
                     /note="hexamer: AATAAA"
     polyA_site      4673
                     /gene="ZNF721"
                     /note="major polyA site"
ORIGIN      
        1 acagcggggc gtcacctcgg acatacgaac agcgggcggt gttcccggct ccgtggggcc
       61 gtcttcccgg cgagtccgcg acggtcgccg cccacggcga ggaaccctta acattcaggg
      121 atgtggccat agaattctct ccagaagagt ggaaatgcct ggaccctgcc cagcagaatt
      181 tgtatagaga tgtgatgttg gagaactaca gaaacctggt ctccctagct atgtgttctc
      241 atttcaccca agactttttg ccagtgcagg ggatagaaga ttcattccac aaacttatac
      301 tgagaagata tgagaaatgt gggcatgata atttacaatt aaggaaaggc tgtaaaagta
      361 tgaacgtgtg taaagtgcag aagggagttt ataatggaat taataaatgc ttgtcaaata
      421 ctcagagcaa aatatttcaa tgtaatgcac gtgtcaaagt ttttagtaaa tttgcaaatt
      481 caaacaaaga taagacaaga catactggag agaaacactt taaatgtaac gaatgtggca
      541 agtcatttca gaagttctca gacctaactc aacataaagg aattcatgct ggagagaaac
      601 cctacacttg tgaagaacgt ggcaaagact ttggatggta cacagacctg aatcaacaca
      661 agaaaattca tactggagag aaaccttaca aatgtgaaga atgtggcaaa gcctttaata
      721 ggtcaacaaa ccttactgca cataagagaa ttcacaacag agagaaagct tacacaggtg
      781 aagatcgtga cagagccttt ggatggtcca caaacctgaa tgaatataag aaaattcata
      841 ctggagataa accctacaaa tgtaaagaat gtgggaaagc ctttatgcat tcctcacacc
      901 tgaataaaca tgagaaaatt catactggag agaaacccta caaatgtaag gaatgtggca
      961 aagtcatttc ctcatcctca agctttgcta aacataagag gattcatact ggcgagaaac
     1021 cctttaaatg tttagaatgt ggtaaagcct ttaatatttc cacaaccctt actaaacata
     1081 ggagaattca tactggagag aaaccctaca catgtgaagt atgtggcaaa gcctttagac
     1141 agtccgcaaa cctttatgta cataggagaa ttcatactgg agagaaaccc tacacatgtg
     1201 gagaatgtgg caaaaccttt agacagtccg caaaccttta cgtacatagg agaattcata
     1261 ctggagagaa accttacaaa tgcgaagact gtggcaaagc ctttggacgg tacacagccc
     1321 tgaatcaaca caagaaaatt catactggag agaaacctta caaatgtgaa gagtgtggca
     1381 aagcctttaa tagttcaaca aaccttactg cacataagag aattcacacc agagagaaac
     1441 cctacacatg tgaagatcgt ggcagagcct ttggattgtc cacaaacctg aatgaatata
     1501 agaaaattca tactggagat aaaccctaca aatgtaaaga atgtgggaaa gcctttatac
     1561 attccttgca cctgaataaa catgagaaaa ttcatactgg aaagaaaccc tacaaatgta
     1621 agcaatgtgg caaagtcatt acctcatcct caagctttgc taaacataag aggattcata
     1681 ctggcgagaa accctttgaa tgtttagaat gtggtaaagc gtttactagt tccacaaccc
     1741 ttactaaaca taggagaatt catactggag agaaacccta cacatgtgaa gtatgtggca
     1801 aagcctttag acagtccgca atcctttatg tacataggag aattcatact ggagagaaac
     1861 cctacacatg tgaagaatgt ggcaaaacct ttagacagtc cgcaaacctt tatgtacata
     1921 ggagaattca tactggagag aaaccttaca aatgtgaaga gtgtggcaaa gcctttggac
     1981 ggtacacaga cctgaatcaa cacaagaaaa ttcatactgg agagaaactt tacaaatgtg
     2041 aagagtgtgg caaagacttt gtatggtaca cggacctgaa tcaacagaag aaaatttaca
     2101 ctggggagaa accttacaaa tgtgaagagt gtggcaaagc ctttgcccca tcaacagacc
     2161 tgaatcaaca cacgaaaatt cttactggag agcaaagtta caaatgtgaa gagtgtggca
     2221 aagcctttgg atggtccata gccctgaatc aacacaagaa aattcatact ggagaaaaac
     2281 cttacaaatg tgaagagtgt ggcaaagcct ttagtaggtc aagaaacctt actacacata
     2341 ggagagttca cactagggag aaaccctaca aatgtgaaga tcgtggcaga tcctttggat
     2401 ggtccacaaa cctgaacgaa tataagaaaa ttcatactgg agataaactc tacaaatgta
     2461 aagaatgtgg gaaagtgttt aaacagtcct cacacctgaa tagacatgag aaaattcata
     2521 ctggaaagaa accctacaaa tgtaaggaat gtggcaaagt cattacgtca tcctcaagct
     2581 ttgctaaaca taagaggatt catacaggtg agaaaccctt taaatgttta gaatgtggta
     2641 aagcgtttac tagttccaca acccttacta aacataggag aattcatact ggagagaaac
     2701 cctacacatg tgaagaatgt ggcaaagcct ttagacagtc agcaatcctt tatgtacata
     2761 ggagaattca tactggagag aaaccctaca catgtggaga atgtggcaaa acctttagac
     2821 agtctgcaaa tctttatgcg cataagaaaa ttcatactgg agagaaaccc tacacgtgtg
     2881 gagactgtgg caaaaccttt agacagtctg caaatcttta tgcacataag aaaattcata
     2941 ctggagataa aaccatacaa gtgtaaagaa tgtggcaaag cctttaagtc atactacagc
     3001 attcttaaac ataagagaac tcataccagg ggaatgtctt acgaaggtga cgaatgtcgc
     3061 ggtctttaaa tgctcctcaa tcctttctaa tcataagata attcataatg aagagaaact
     3121 ctaaaatgtg aaaaatgtga gaaggctttt aatcacacct caatctgttg tagacataag
     3181 agtaattata ttgatgagaa gccaaattaa aattaaaaat gtggcaaaga cttccaattc
     3241 tagtcagttc ttaatgtaat tcctactgaa gaaaacacct ggaaatacaa aaaatgtggc
     3301 aaaacttgta accaatgctt agcatttttg cacatgatag tatttatatg tgagactact
     3361 tgtacaaaca taaaaatata caaaagctat tgtctacttg aaatttatag ttaataaaag
     3421 cattataaat gtaatttctg ttgaaagacc ttttagaaaa tataggccat taaagtgaag
     3481 aatagtctta agacagagaa tacaaagata aagagggctc tagtacctgt acttgtatcc
     3541 cagaacttac tatatgcatt ttgtactaga ggaaaactct gaagcagttg cttaaacttt
     3601 gttcaacatc agagaattta tattggagag aaatcctaca aatgtaataa atgtggaaaa
     3661 acctctgttc agaaactgca ggttaagaaa ccagaggcca ggcgcggtgg ctcacgcctg
     3721 taatcccaac actttgggag gccaaggagg gtggatcacc tgaggtcggg agttcaagga
     3781 cagcctgacc aatatggaga aacctcgtct gtactaaaaa tacaaaaatt agcaggacat
     3841 ggtggtgcat ggctgtaatc ccagctactc aggaggctga gacaggagaa tggcttgaac
     3901 ccaggaggtg gaggttgcgg tgagctgaga tcgtgccatt gcactccagc ctgggtaaca
     3961 agagtgaaac tctgtctcaa aacaagataa aaagaaaaga aacaccagag aatttttact
     4021 agaatataat ttgtaggtgc agtaaatgtg aagaaatatt taggctaaaa ttaagactat
     4081 gtaaacatca gaggatttac agtagaaaga actaaggaac taacacttca gactttaaaa
     4141 taaatcagag tattaagtat aacaaaagtt gaacctgtta gaaaatttcc ttgtatataa
     4201 gttgaaaagt aggtttttga agagatatat tcgaaatata ttttttcact tgaaaaaagt
     4261 aaaaattttt ttcaaaagca aataattcaa ctctaaaatt atactatttc aacattctca
     4321 tttatgtgaa agcatgtgat aaattgttgc tgcgtcagag atatgagaaa ctcctttgca
     4381 ttaggtgggc attattcata gacttctaca tgaaagagaa gagaaataaa agatgcacca
     4441 ggaaaatctg agcagagagg cttttagtgg ttgacttact gagtgatgcc tgaagtaggt
     4501 gttcagagta atactttgcg ttatactgag agagaatctg aattttagta gtaaattgtt
     4561 ttgccaactg tatatttatg taataagtgc aataaaatgc agtaaatttt aaaattctct
     4621 taagataatg tgtgaactta atttttgaaa taaaaattgt tattgtgtta aaa
//
