LOCUS       NM_001100598            2185 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 707 (ZNF707), transcript variant
            2, mRNA.
ACCESSION   NM_001100598
VERSION     NM_001100598.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2185)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2185)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2185)
  AUTHORS   Xin,X., Rual,J.F., Hirozane-Kishikawa,T., Hill,D.E., Vidal,M.,
            Boone,C. and Thierry-Mieg,N.
  TITLE     Shifted Transversal Design smart-pooling for high coverage
            interactome mapping
  JOURNAL   Genome Res 19 (7), 1262-1269 (2009)
   PUBMED   19447967
REFERENCE   4  (bases 1 to 2185)
  AUTHORS   Rual,J.F., Hirozane-Kishikawa,T., Hao,T., Bertin,N., Li,S.,
            Dricot,A., Li,N., Rosenberg,J., Lamesch,P., Vidalain,P.O.,
            Clingingsmith,T.R., Hartley,J.L., Esposito,D., Cheo,D., Moore,T.,
            Simmons,B., Sequerra,R., Bosak,S., Doucette-Stamm,L., Le Peuch,C.,
            Vandenhaute,J., Cusick,M.E., Albala,J.S., Hill,D.E. and Vidal,M.
  TITLE     Human ORFeome version 1.1: a platform for reverse proteomics
  JOURNAL   Genome Res 14 (10B), 2128-2135 (2004)
   PUBMED   15489335
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB249556.1, DA007942.1, AK001126.1, CV023324.1, BC014894.1,
            AK055263.1 and AW294133.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001100598.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 4. Variants 1, 2, 3, 4, and 5 encode the same
            protein (isoform a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK290432.1, DA474624.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000358656.9/ ENSP00000351482.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-13                DB249556.1         28-40
            14-548              DA007942.1         12-546
            549-738             AK001126.1         507-696
            739-739             CV023324.1         519-519
            740-1383            AK001126.1         698-1341
            1384-1995           BC014894.1         1445-2056
            1996-2146           AK055263.1         1999-2149
            2147-2185           AW294133.1         17-55               c
FEATURES             Location/Qualifiers
     source          1..2185
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.3"
     gene            1..2185
                     /gene="ZNF707"
                     /note="zinc finger protein 707"
                     /db_xref="GeneID:286075"
                     /db_xref="HGNC:HGNC:27815"
     exon            1..64
                     /gene="ZNF707"
                     /inference="alignment:Splign:2.1.0"
     exon            65..162
                     /gene="ZNF707"
                     /inference="alignment:Splign:2.1.0"
     exon            163..229
                     /gene="ZNF707"
                     /inference="alignment:Splign:2.1.0"
     CDS             215..1330
                     /gene="ZNF707"
                     /note="isoform a is encoded by transcript variant 2"
                     /codon_start=1
                     /product="zinc finger protein 707 isoform a"
                     /protein_id="NP_001094068.1"
                     /db_xref="CCDS:CCDS47932.1"
                     /db_xref="GeneID:286075"
                     /db_xref="HGNC:HGNC:27815"
                     /translation="MDMAQEPVTFRDVAIYFSREEWACLEPSQRALYRDVMLDNFSSV
                     AALGFCSPRPDLVSRLEQWEEPWVEDRERPEFQAVQRGPRPGARKSADPKRPCDHPAW
                     AHKKTHVRRERAREGSSFRKGFRLDTDDGQLPRAAPERTDAKPTAFPCQVLTQRCGRR
                     PGRRERRKQRAVELSFICGTCGKALSCHSRLLAHQTVHTGTKAFECPECGQTFRWASN
                     LQRHQKNHTREKPFCCEACGQAFSLKDRLAQHRKVHTEHRPYSCGDCGKAFKQKSNLL
                     RHQLVHTGERPFYCADCGKAFRTKENLSHHQRVHSGEKPYTCAECGKSFRWPKGFSIH
                     RRLHLTKRFYECGHCGKGFRHLGFFTRHQRTHRHGEV"
     exon            230..356
                     /gene="ZNF707"
                     /inference="alignment:Splign:2.1.0"
     exon            357..470
                     /gene="ZNF707"
                     /inference="alignment:Splign:2.1.0"
     exon            471..2185
                     /gene="ZNF707"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2185
                     /gene="ZNF707"
                     /note="major polyA site"
ORIGIN      
        1 gtaaaagtct gggctaccgg cgcggcgtag tggatgcagc atcctagtgg aggacgcccc
       61 tgtgttgctg aacctgtttg catgagttgc tcctgacggc cctttaggat acttccatgt
      121 ctgtagggtc tagagtgaca tctcctcccc tcccctgacg agatctgccc tccttggcac
      181 tgtgcttccc cagaggggtg gcctcgctgt tcccatggac atggcccagg agccagtgac
      241 cttcagggac gtggccatct acttctcaag ggaggagtgg gcgtgtctgg aacccagcca
      301 gagggccctc taccgggacg tgatgctgga caacttcagc agtgtggctg ctctgggatt
      361 ttgcagcccc agaccagacc tcgtctctcg cctggaacag tgggaggagc cgtgggttga
      421 agaccgggag agacctgagt tccaggcagt gcagagggga ccccggccag gggcaaggaa
      481 gtctgcagac cccaagagac cttgtgatca tccagcttgg gctcacaaga aaacccacgt
      541 gcggcgagaa agagccaggg aaggaagcag ctttaggaag ggcttcaggc tggacacgga
      601 tgacgggcag cttcccagag ctgctccaga aaggacagac gccaagccca cggctttccc
      661 gtgtcaggtg ctcacgcagc gttgtgggcg gcggccgggc cgcagagagc gccggaagca
      721 gcgcgcagta gagctgtcat tcatctgcgg cacgtgcggg aaggcgctca gctgccacag
      781 ccggctgctc gctcaccaga cggtgcacac gggaaccaag gccttcgagt gccccgagtg
      841 cggccagacc ttccggtggg cttcaaacct gcagcgccac cagaagaacc acacgcgcga
      901 gaagcccttc tgctgcgagg cctgcgggca ggcgttcagc ctgaaggacc gcctggctca
      961 gcaccgcaag gtccacaccg agcacaggcc ctactcgtgt ggcgactgtg ggaaagcctt
     1021 caagcagaag tccaaccttc tcagacacca gctggtgcac accggggagc ggccgttcta
     1081 ctgcgcggac tgcggcaaag ccttccggac caaggagaac ctcagccacc accagagggt
     1141 ccacagcggg gagaagccct acacctgtgc cgagtgcggc aagtccttcc ggtggcccaa
     1201 gggcttcagc atccaccgga ggctgcacct gacgaagagg ttctacgagt gcggccactg
     1261 tgggaaaggc ttccgtcacc tggggttctt cacgcggcat cagaggactc acaggcacgg
     1321 ggaggtgtag gggcgcccga agagtggggt gctgcgcctc tgcgggagta ctgggtcctg
     1381 agggagagct gcagtgagaa gttgctcttc agcctggaaa atcaacctga attcagagaa
     1441 gccttcttag tcctcagagc tccccagtcc cccgagaagt ttactgggaa aactgccagg
     1501 tgggagaagc agagccatgg gtacgccgga gatggcgggg gctctggaga tggcgggggc
     1561 tgcgccccgg cgccgggcat cctggggatg tgctgagagt gtgcgcgacc ccggagccac
     1621 gtgccaggcc gggctcagag gcggagaagc ctgcctggtg cccacagccg tctggctcag
     1681 ggactccacc ctggccccga gtcgccgtct gctgggcctt tccttcctgg ctctgcaccc
     1741 catgctggct gcccggtctg gcttcccttc ttgtctctgt cttgggcgag gcagctgtga
     1801 gcattgcaca gaggcaaaga ccctcctgca gcctctgcgc tgggccgtag aaacaagagc
     1861 ctttgtaata ctgaacctca ttcaaggatt aggagtggtg gttaggtcag ggccaccccc
     1921 agtgctgcag gaacggcctc cacccagctc tgttggtcag agcctgggtc atgcacctgg
     1981 agttgggaga tcaagttggg tctcagggca gtgaggtggc catatccacc acatcgcatt
     2041 tcgtggggga agaggtgacc tctttgtttt aaacttaagg tgtctgctta tccagccaga
     2101 aataaaaatc tgccagtggt gttcccaagg gaagaccccc gtgggaatgg gtcgggacac
     2161 tgccgtgttt caggttagcc aatta
//
