LOCUS       NM_001080470            5579 bp    mRNA    linear   PRI 17-OCT-2024
DEFINITION  Homo sapiens zinc finger protein 697 (ZNF697), mRNA.
ACCESSION   NM_001080470 XM_371286
VERSION     NM_001080470.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5579)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL109966.36.
            
            On Nov 29, 2018 this sequence version replaced NM_001080470.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DR731370.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000421812.3/
                                                ENSP00000396857.2
            RefSeq Select criteria           :: based on conservation, longest
                                                protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-499               AL109966.36        88430-88928         c
            500-576             AL109966.36        88353-88429         c
            577-839             AL109966.36        66537-66799         c
            840-5579            AL109966.36        60039-64778         c
FEATURES             Location/Qualifiers
     source          1..5579
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p12"
     gene            1..5579
                     /gene="ZNF697"
                     /gene_synonym="ZFP697"
                     /note="zinc finger protein 697"
                     /db_xref="GeneID:90874"
                     /db_xref="HGNC:HGNC:32034"
                     /db_xref="MIM:620981"
     exon            1..576
                     /gene="ZNF697"
                     /gene_synonym="ZFP697"
                     /inference="alignment:Splign:2.1.0"
     exon            577..839
                     /gene="ZNF697"
                     /gene_synonym="ZFP697"
                     /inference="alignment:Splign:2.1.0"
     CDS             614..2251
                     /gene="ZNF697"
                     /gene_synonym="ZFP697"
                     /codon_start=1
                     /product="zinc finger protein 697"
                     /protein_id="NP_001073939.1"
                     /db_xref="CCDS:CCDS44202.1"
                     /db_xref="GeneID:90874"
                     /db_xref="HGNC:HGNC:32034"
                     /db_xref="MIM:620981"
                     /translation="MKQEDNQGVCAHQDSEDKGMGSDFEDSEDREGDPEEREMGSNPH
                     DTNKREGHPEPEMGSNPQDSRHREAVPDICTEGQLSEEEGVSVRGEEDDQSGVADMAM
                     FPGLSESDSISRSLREDDDESAGENRLEEEEEQPAPPVLPWRRHLSLGSRHRGDKPAH
                     RRFHRLHHPMAVDLGELDSLVASIMDAPTICPDCGESFSPGAAFLQHQRIHRLAEAAA
                     AASLEPFGLAGECDAMVGMMGVGVAGGFGAGPPLARPPREKPFRCGECGKGFSRNTYL
                     TNHLRLHTGERPNLCADCGKSFSWRADLLKHRRLHTGEKPYPCPECGEAFSLSSHLLS
                     HRRAHAAASGAGAAALRPFACGECGKGFVRRSHLANHQRIHTGEKPHGCGECGKRFSW
                     RSDLVKHQRVHTGEKPYMCSECGETFSVSSHLFTHKRTHSGERPYVCRECGKGFGRNS
                     HLVNHLRVHTGEKPFRCGQCEKRFSDFSTLTQHQRTHTGEKPYTCIECGKSFIQSSHL
                     IRHRRIHTGNKPHKCAGCGKGFRYKTHLAQHQKLHLC"
     exon            840..5579
                     /gene="ZNF697"
                     /gene_synonym="ZFP697"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5512..5517
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF697"
                     /gene_synonym="ZFP697"
                     /note="hexamer: ATTAAA"
     polyA_site      5534
                     /gene="ZNF697"
                     /gene_synonym="ZFP697"
                     /note="major polyA site"
     regulatory      5559..5564
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF697"
                     /gene_synonym="ZFP697"
                     /note="hexamer: ATTAAA"
     polyA_site      5579
                     /gene="ZNF697"
                     /gene_synonym="ZFP697"
ORIGIN      
        1 agtgaggagt cagccgggca gccagccagc gagccagcca gccagccagc cagccagcca
       61 gccaaccagc cagccagcgg gccacccagc ggccgctgca gccgccgccg ccgcacaagg
      121 gcagacgcgc tgcggtgcgg ggctcgggcc ggggcgctcg gtgccctagc tcctcgccgc
      181 gccagccgcc tcgcaggtag gagcgtggct gtggctgggc tcaaccgcct cccggggatg
      241 gggctgatcg ggaccagacc cgaccgctgc ggggatgggg tgtgtgttcg agtgcggtgg
      301 cggaacggct gggcgaagtt gtgcctcgta aagtggaccg ttgtccgctc ccctggggcg
      361 cagggccccg ggcttatggg gtgctctcgc gcccccaaag ccaggactga gctccctcag
      421 gggtatgtgg cgaggggcgg ggaggaggag gctgagactt gagggaggag acagcgatgc
      481 aagagggaat aggaccgtcc cgccgaccac cgaagggggc atcagagacc ctcggagaaa
      541 ccaagcccag ggaggagctt ggaaggcaag gagaagggat tcctggtcac ctcccttgct
      601 cttttcttcc tggatgaaac aagaagataa tcagggtgtc tgtgcacacc aggactcaga
      661 agacaaaggg atgggttctg attttgagga ctctgaggac agggaagggg acccagaaga
      721 aagagaaatg ggctctaatc cacatgacac aaacaagaga gaaggccatc cggagccgga
      781 gatgggctcc aacccacagg actcaaggca cagggaagca gtgcccgaca tctgcacaga
      841 ggggcagctg agtgaggaag aaggcgtttc tgtccgtggg gaagaggatg accaatccgg
      901 tgtagctgac atggcgatgt tcccaggact gtctgagtct gacagcatat cccggagcct
      961 ccgggaggac gacgacgaga gtgctgggga gaaccggctg gaggaggaag aggagcagcc
     1021 ggcccctccc gtacttccct ggaggcgaca tctctccctg gggagtcggc accgaggtga
     1081 caagcccgcc caccgccgct tccaccggct ccaccacccc atggccgtgg acctcgggga
     1141 gctggatagc ctggtggcca gcatcatgga cgcgcccacc atctgccccg actgcgggga
     1201 gagcttcagt cctggcgccg ccttcctgca gcaccagcgc attcaccgcc tggctgaggc
     1261 cgctgccgcc gccagcctgg agcccttcgg cctggcgggc gagtgcgacg cgatggtggg
     1321 catgatgggg gtgggtgtgg cggggggctt cggggccggg cccccgctgg cccggccccc
     1381 gcgcgaaaag cccttccgct gcggggagtg cggcaagggc ttcagccgca acacctacct
     1441 gaccaaccac ctgcgcctgc acacgggcga gcggcccaac ctgtgcgccg actgcggcaa
     1501 gagcttcagc tggcgcgccg acctgctcaa gcaccggcgc ctgcacacgg gcgagaagcc
     1561 ctacccgtgc cccgagtgcg gcgaggcctt cagcctcagc tcgcatctgt tgagccaccg
     1621 gcgcgcgcac gcggcggcca gcggcgcggg ggcggcggcg ctgcggccct tcgcctgcgg
     1681 ggagtgcggc aagggcttcg tgcgccgttc gcacctggcc aaccaccagc gcatccacac
     1741 gggcgagaag ccgcacggct gtggcgagtg cggcaagcgc ttcagctggc gctcggactt
     1801 ggtgaagcac cagcgcgtgc acacgggcga gaagccctac atgtgctccg agtgcggcga
     1861 gaccttcagc gtcagctcgc acctcttcac gcacaagcgc acgcactcgg gtgagcggcc
     1921 ctacgtgtgc cgcgagtgcg ggaagggctt cgggcgtaac tcgcacctgg tgaaccacct
     1981 gcgcgtgcac accggcgaga agcccttccg ctgtggccag tgcgagaagc gcttcagcga
     2041 cttctccacg ctcacgcagc accagcgcac gcacacgggc gagaagccct acacgtgcat
     2101 cgagtgcggc aagagcttta tccagagctc ccacctgatc cgccaccgcc gcatccacac
     2161 gggcaacaag ccgcacaagt gtgcgggctg cggcaaaggc ttccgctata aaacgcacct
     2221 cgcgcagcac cagaagctgc acctgtgtta ggggctgggt ccgcgggagg ctgccgtctg
     2281 gggagcctgt ggggggtaga tatcctggga ctgacccagg ggaaggaagt ggggaagggg
     2341 cgggagggac aatctgagag tgactgggga gcctttggtg tttggggttt cctgaagtgg
     2401 gaggagtgtt gagtaagttg gtctttcccg gtgctatact tgcctcctct ccacggaaga
     2461 attgttcagg agatgcgctt ggggtgatga cttccttaaa tacacgctgt agggggtgaa
     2521 gagcttggag gaccaggcac tttgaggaag ggcagttcgt gggctggggt gggaacagga
     2581 tggcgggcaa tagactaggg taggccgcga tggcctgtag aaggttgcgg ggagagggtt
     2641 taaatgaggg ttatggggcg aaataaaacc aagtataagt gattctatct tggtcccacc
     2701 aagagtttgc ccgatctcca cacatcacct gttgtctcac aaaaagtagg ggaaccttgt
     2761 cagtcacata ggacaggata tttaatgtac ttttcctttc tctgagccac agttagctgc
     2821 tattttgagg catccaaggg gaagtgggct gaaaaacgcc acactcattt caaggggcaa
     2881 tgtctggggt ttagaaattc atttataact ggttctctga tgtgggaaat cctgattctg
     2941 tcccgggttc tttgctactt ccttgaaaat actctagctt catgctgggt caaggtggtt
     3001 tacctggatg acccccctcc cccgccctcg cccatcccag gtgtgtgcca cacccagtat
     3061 ttctttcagg tctcaactgt ggtgttttaa gtgcagggaa aaggaacaat cacagctatg
     3121 tgtgactttc cttttcccac ctcaccttga tgtaggtgtt tcaagtgaac tttagaccaa
     3181 cagttgccca gtgacctgct aaaaagtcaa ctagctcaga gttttgctgg cctttatgtg
     3241 agaaatccaa gaaagtgttc acttttttgg gatgcgagac tccttggtct catttgcctt
     3301 cactttgcat ttgttagtga cctccactaa cccccacttc catgcatatt gacgagggat
     3361 ctagtctaag taagaatgtc ttttgcctgc gcgtggaggc acagtagaaa tctcaaggct
     3421 ttacccagaa gagcccagtc agggagaggt gtaaatgcaa aattgccaaa tagcacaaac
     3481 aatgaatgtt ttctggttgt tatatagatg ccaaaatagc actttgatat ttgcaaagtg
     3541 ctttatgctt tttaataatt gttagctgtt tctcacatca ttgtgagtta gatcagtatt
     3601 atgaccgctg tcttagggaa ggcctgggaa caggagtgtg caggctgtcc tgaagagagg
     3661 ctgaggacag tgtgaataat tgtagcctga ccttttgcat tctccagctc agctgctagg
     3721 aagacttact tgtcatgatt tatataataa aattaaggac actgaaaatt cttatgcttg
     3781 atgaaaaact taaggctagc ctagaagggc caaacatgtc cttattgaca aagctggtct
     3841 ttgtcgccta attagggtat cctagctatg ttccatttct agtaaggggc tgtagttaga
     3901 tgactcttgt atagatttca gttacttatg ctgaagatcc ctgtgctagg ttagccttta
     3961 gaagttagag ttgtggaaag cagtattgtt ttcttctcta gtgattgtta ccctacacat
     4021 ttcatggaag catcttcaca aaatatcaga cacagtggaa gggggaaaaa aagctacgag
     4081 attgttttta cacttttagc aaagtttctg tggatgctag taatttatac ttgatcagtt
     4141 gtattctagt aaagaacctc tttggggact gtaggaaagc atgtttttgt ggttataaaa
     4201 acacttaaaa atcctgataa ttctgggctt gtataatgcc tgttgatctt gccctcttaa
     4261 tcagtttatt gttattcaca aatgcaaata ggttttcaaa ctacagacag ttttgaaaga
     4321 cattaattct cattttcttc tagtcaggag taatacaagc aaacaagtgt ccgttttgaa
     4381 ttctgatttg taatctgaat actaaacata ttagacccac ctgaaaataa tatagccaat
     4441 ttctaggtaa tcttactgct ttgtgggttt ctttccatgt acatctacct cttccagctg
     4501 ttttaagttt tctcaagtct gtgcctatga aatctcatcc aacttttgat tattcatgga
     4561 ttgattatcc gctttttttt tgcttttttg ctgccattgc tatgcctggt ctcgtctgca
     4621 tcaaatatac tacatatcag caactttaga gaatgggttc aacagggagt ggagagtgaa
     4681 gctaatgtaa aatagtttag tggcagtggg aatctttgga cttcatttac ctctctcatt
     4741 atttctatta ccatggataa aaaagtcagc tgctacgttg atatcccttc tatgagcaca
     4801 ttcttagcag aagaaaacaa tccaactacc aacacccgac tctattggtg catttaaaat
     4861 gtgattccat tttttcttac aattcttcag ggaacttacc tgcattaagt gaggttaaat
     4921 gcattcagga ggttgtttgt ttcttctatc tagttttaga ataatatttc ttcggcaaac
     4981 cctgctaact gcggttcacc cttgaaaacg ttaatctgag gactttttcc accaactcat
     5041 taatgatggt ggaagcaagt gtattatttg tttcctggag aatttgatga agagcagtct
     5101 tcctctgctg ccctttacta agcaaaacct ggagcaattt aaataggcta aatggttttg
     5161 attaaatctt gagctccgag ttggaaggag aaaatgagaa gttaacccct tgagccatgt
     5221 ggtctcttta caatcaagag actgtacata tgtgaaaaaa tacaaattaa ggacctgtgt
     5281 tcatagacaa tctaaactgt gtttctgaag tttgtgcaca tttttcttca ctgtaatgtt
     5341 attttacagc tgtttgttaa aatagtgaat aatttaatga tcctaaaagt aacaggtttc
     5401 gtgtgagtgt gcttgtatac gtgagatttg ccttattttc aggttgtttt atttaacgat
     5461 ggttccttgg acagcattct ggtgttcagc aaccaatatg gaatatttgt cattaaatcc
     5521 atatcagtct tttaccatgt cattcttctt tgccacacat taaatgtcac tcagctcta
//
