LOCUS       NM_030895               4658 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens zinc finger protein 696 (ZNF696), mRNA.
ACCESSION   NM_030895
VERSION     NM_030895.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4658)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 4658)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 4658)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC138696.4 and AK024191.1.
            
            On May 17, 2019 this sequence version replaced NM_030895.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK024191.1, BC126317.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1966682, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000330143.8/ ENSP00000328515.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-134               AC138696.4         152620-152753
            135-1314            AK024191.1         126-1305
            1315-4658           AC138696.4         157812-161155
FEATURES             Location/Qualifiers
     source          1..4658
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.3"
     gene            1..4658
                     /gene="ZNF696"
                     /note="zinc finger protein 696"
                     /db_xref="GeneID:79943"
                     /db_xref="HGNC:HGNC:25872"
     exon            1..351
                     /gene="ZNF696"
                     /inference="alignment:Splign:2.1.0"
     exon            352..445
                     /gene="ZNF696"
                     /inference="alignment:Splign:2.1.0"
     CDS             382..1506
                     /gene="ZNF696"
                     /codon_start=1
                     /product="zinc finger protein 696"
                     /protein_id="NP_112157.2"
                     /db_xref="CCDS:CCDS6399.1"
                     /db_xref="GeneID:79943"
                     /db_xref="HGNC:HGNC:25872"
                     /translation="MEPGGEPTGAKESSTLMESLAAVKAAFLAQAPSGSRSAEVQAAQ
                     STEPAAEAGAPEGEGHRGGPPRALGSLGLCENQEARERPGGSPRGPVTSEKTGGQSGL
                     ESDVPPNAGPGAEGGGSWKGRPFPCGACGRSFKCSSDAAKHRSIHSGEKPYECSDCGK
                     AFIHSSHVVRHQRAHSGERPYACAECGKAFGQSFNLLRHQRVHTGEKPYACADCGKAF
                     GQRSDAAKHRRTHTGERLYACGECGKRFLHSSNVVRHRRTHHGENPYECRECGQAFSQ
                     SSNLLQHQRVHTGERPFACQDCGRAFSRSSFLREHRRIHTGEKPHQCGHCGRAFRALS
                     GFFRHQRLHTGEKPFRCTECGRAFRLSFHLIQHRRVHGAE"
     exon            446..4658
                     /gene="ZNF696"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2746..2751
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF696"
                     /note="hexamer: AGTAAA"
     polyA_site      2767
                     /gene="ZNF696"
                     /note="major polyA site"
     regulatory      4165..4170
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF696"
                     /note="hexamer: AATAAA"
     regulatory      4174..4179
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF696"
                     /note="hexamer: AATAAA"
     polyA_site      4188
                     /gene="ZNF696"
     polyA_site      4195
                     /gene="ZNF696"
                     /note="major polyA site"
     regulatory      4329..4334
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF696"
                     /note="hexamer: AATAAA"
     regulatory      4337..4342
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF696"
                     /note="hexamer: AATGAA"
     polyA_site      4347
                     /gene="ZNF696"
     polyA_site      4353
                     /gene="ZNF696"
ORIGIN      
        1 gtagcgggtg cagtccagct gctctggacg ctgaggcccc ggcttctctt gctggggtgt
       61 cgattcggga gggctgaggg cgcggccgag agaacggggc ggtcaccgcc gccgtggccc
      121 gcgcgtcccg cgctctcctt gcagtgcagg ccccagccgc tctcgggcgc ggcgtggggg
      181 aggcggccct gcaggtgcgt acccggggtc cgacacgtgc ggggcttcct gcgagctgag
      241 tccccgctgc gcgtcttcag gcctttgtaa gttgtcaaat ttcccaccgg cccagctcat
      301 cgagcttctt cccagctgtg aacaggaggg cctgttccct aattcttgcc gaaattgttc
      361 caactgctgg tgttctgcaa gatggagcca ggaggagagc ccacaggtgc taaagagagc
      421 agtaccctga tggagtccct tgcagctgtg aaggctgctt tcctggcgca ggccccgagt
      481 ggcagccggt cagccgaggt gcaggcagct cagagcacgg agcctgccgc agaggcaggc
      541 gctcccgagg gagagggcca cagagggggg cctccccggg cgttggggtc tcttggcctt
      601 tgtgaaaacc aggaagccag agagaggccc ggaggttccc ctcgaggccc ggtcacttct
      661 gagaaaactg gaggacagag tggcctcgag tcagacgtcc ctccgaacgc aggccccggc
      721 gcagagggcg ggggcagctg gaaggggcgg cctttcccgt gcggcgcctg tggccgcagc
      781 ttcaagtgct cctcggacgc ggcaaagcac cggagcatcc actcggggga gaaaccgtac
      841 gagtgcagcg actgcgggaa ggccttcatc cacagctcgc acgtggtccg gcaccagcgg
      901 gcgcacagcg gggagaggcc ctacgcgtgc gccgagtgcg gcaaggcctt cggccagagc
      961 ttcaacctcc tccggcacca gcgcgtgcac acgggcgaga agccctacgc gtgcgccgac
     1021 tgcggcaagg ccttcggcca gaggtcggac gccgccaagc accgccgcac ccacaccggg
     1081 gagaggctgt acgcgtgcgg cgagtgcggg aagcgcttcc tgcacagctc gaacgtggtc
     1141 cggcaccggc ggacccacca cggggagaac ccgtacgagt gccgggagtg cggccaggcc
     1201 ttcagccaga gctccaacct cctccagcac cagcgcgtgc acacggggga gcggcccttc
     1261 gcctgccagg actgcggccg cgccttcagc cgcagctcct tcctccgcga gcaccgccgc
     1321 atccacaccg gggagaagcc ccaccagtgc ggccactgcg ggcgcgcgtt ccgggcgctg
     1381 tcgggcttct tccggcacca gcgactccac acgggcgaga agccgttccg ctgcaccgag
     1441 tgcggccgcg ccttccgcct gagcttccac ctcatccagc accggcgggt gcatggcgcc
     1501 gagtgagccg gggctgcggc ggaagagatg ccggcggcct ggtgggcgcg aggccgaggc
     1561 cgggggaggc tcctgtccgc cccgtgcgcg gtgaggaagt aacagccggc tgcgcgcctg
     1621 gttctcgggt tgcgaaagcc tcgccaggcc tgcatccgcc ttggcttggg agcaatcagg
     1681 agagacaggg ctcggggaag gcgagcgctg cccgcgggag gcgattccca gaggcgggga
     1741 ggtctcaggg gtctgtcccg ggccggccgc ccgcctctga gactccccgc ctcccacggt
     1801 cagctgctgc ggggcagtgg ccggtgattg aatcggtcat tcctccgcaa ccaggcctcc
     1861 atcaaaaccc tgcatgagat gagggcctcg ggcttcgggt tggtgaaggc ggggtggggg
     1921 ggcagttagg aagggggcgc ccagacaggg catggaagcc tcgcgtcctc ccccgtacct
     1981 tgcgggtcgg tggttcatcc atgtatttca acgccttttc acagccggtt catatggtcc
     2041 cgacttctgt gtgcttagaa aattatggaa cttggccggg tgcggtggct cccgcctgta
     2101 atcctagcac tttgggaggc cgaggcgggc ggatcacacg gtcaagagat caagaccatc
     2161 ctggccaaca tggcaaaacc cccatctcga ctaaaaatac aaaaaattaa ttgggcgtgg
     2221 tggcgtgcgc ctgtaatctc agctacttgg gagcctgggg caggagaatc acttgaacct
     2281 gggaggcgga ggttgcagtg agcggagatc tgggcactgt actttagcct gggcgacaga
     2341 gagacccatc tcaaaaaaaa aattggaacc tgagaagggg gtcgtggggt ccccggggcc
     2401 caccgtctgc acttggcatc tgaagtcggg gtggtcttgt gggactgacc ccttaccctg
     2461 tgggttctgc actagctccg ggcaattggt gacagaatcg agttaaattg taggacatcg
     2521 cgttggtgtc tgagagggag ttggagagct ggttggtgtg gagggaaagg cttacacaca
     2581 tgtgatttca gaagcgttct gtgggtagag gaatcgtttt ctctttgaga ctgttatgag
     2641 tatgtacaaa tgttatttcc tgtaaaatat tttcattttt taaaatgtta ttttctagat
     2701 agaaaagtag aagtgtctct ttggggagcg tttttggggg cgtatagtaa agctctgtca
     2761 tcatgaatta agcgaggtgg gctttgagtt tcttgggatg acagggaaat gtgagccgcc
     2821 tactggccgt gagcccctgg ggtgcggttg caggattcgc ccatcctggt ctgggtgtgg
     2881 cttgtgacca cctcctgcag ttctctgccc aggtaaggac taattgggaa gaattctggg
     2941 tcctgagctg gctgccgctt ccaagacagt cgctttgagg gctcttggca ccgattttgt
     3001 taaaatgcat gagcttaggg ttgtgcagcc tgtaggggca ggggtggtct cagaatggat
     3061 ttggtggccc caccgttaat taagctcctg acccctgggc cggtggtgag gtgggaagat
     3121 gagcctgtgt ctcccatgct gagccaagat cctcaggtac cagtagcggt caaagcacct
     3181 gctccctgaa ggaagcttac ctggcttagc ctcattcctg ctcgtaagtc aggcattcag
     3241 cttgcaaaga tccccaagca cacaaggaga gtcagctgac tgagggccaa cagaaacagc
     3301 aggcagccgc tgtcagccac aaagaaacgc agatcctgaa actgtcatca tacaggtgag
     3361 aggatagtta tgtgtgaggt gttcaaagaa gtcgcgcagt cagtgatgag aaagctgtag
     3421 ggtacatact gtcacgcatg aataggcagg actccttaaa gaacttttgg aaatgaaaaa
     3481 caggccaggt gcagtggttc atgcctataa tcccaacact ttgggaggcc taagggggag
     3541 gatcacttga gcctaggagt tcaagaccag cctaggcaac atagggctgg gcacggtggc
     3601 tcacgcctgt aattccagca ctttgggagg ctgaggcagt ggatcacctg aggtcaggag
     3661 tttgagacca ccctggccaa catggcaaaa ccccatttct actaaaaata caaaattagc
     3721 tgggcatggt ggcccacacc tgtaatccca gctactcggg cagctgaggc aggagaatcc
     3781 cttgaacctg ggaggcagaa gatgcagtga gccgagatca cgccattgca ctccagcctg
     3841 ggcaaaaaga gcaaaactcc atcttaaaaa aataaataaa taaaggaaaa tgagccgagt
     3901 gatggtctta gatataagat ggaatggcaa gcaaataaaa ttataaatat gaatacatat
     3961 gtatatataa aagaatagtg tcaactaaaa tactagacaa caatagcatg taaattagaa
     4021 gggacagaaa tgttctaaga ccctccggtt gttgggaaga gggtgtaaga tagtgtttaa
     4081 tttgactttg ataagttaaa tgtgcatagt gtaatttaat gttaattact aaaagagtgt
     4141 aaccagtcta tacatctcta atccaataaa aagaataaaa cactgtgatt taaaatgtag
     4201 tcccagctgc ttgggagact gaggcaggag gatctcggct tggatcctca gaccaggagt
     4261 ttgaggcagc agtgagctac gattgtgccg ctgcactcca gactggacaa cacagtgaga
     4321 gcccataaaa taaataaatg aactgaacac aaacttctgt caattaaaaa ataagaacga
     4381 aatcaggctg ggcctgagcg ctgtggctca cacctgtaat cccagcactt tggaggccaa
     4441 ggtgggtgga tcgcttaagc ccaggagttc gaaaccagcc tgggcaacat agggagaacc
     4501 tgtctctaca aaaaatacag taagtaagcc tatagttcca gccacccagg aggctgaggt
     4561 gggaggatca cctgagcctg ggagctcgag actgcagtga gctgtagtca taccactaca
     4621 ctccagcctg ggcaaaagag tgagaccctc tctcaaaa
//
