LOCUS       NM_020394               3341 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens zinc finger protein 695 (ZNF695), transcript variant
            1, mRNA.
ACCESSION   NM_020394
VERSION     NM_020394.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3341)
  AUTHORS   Chen,J., Sun,M., Chen,C., Jiang,B. and Fang,Y.
  TITLE     Identification of hub genes and their correlation with infiltration
            of immune cells in MYCN positive neuroblastoma based on WGCNA and
            LASSO algorithm
  JOURNAL   Front Immunol 13, 1016683 (2022)
   PUBMED   36311753
  REMARK    GeneRIF: Identification of hub genes and their correlation with
            infiltration of immune cells in MYCN positive neuroblastoma based
            on WGCNA and LASSO algorithm.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3341)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 3341)
  AUTHORS   Takahashi,T., Yamahsita,S., Matsuda,Y., Kishino,T., Nakajima,T.,
            Kushima,R., Kato,K., Igaki,H., Tachimori,Y., Osugi,H., Nagino,M.
            and Ushijima,T.
  TITLE     ZNF695 methylation predicts a response of esophageal squamous cell
            carcinoma to definitive chemoradiotherapy
  JOURNAL   J Cancer Res Clin Oncol 141 (3), 453-463 (2015)
   PUBMED   25273507
  REMARK    GeneRIF: ZNF695 methylation was associated with the response to
            definitive chemoradiotherapy in esophageal squamous cell carcinoma.
REFERENCE   4  (bases 1 to 3341)
  AUTHORS   Juarez-Mendez,S., Zentella-Dehesa,A., Villegas-Ruiz,V.,
            Perez-Gonzalez,O.A., Salcedo,M., Lopez-Romero,R., Roman-Basaure,E.,
            Lazos-Ochoa,M., Montes de Oca-Fuentes,V.E., Vazquez-Ortiz,G. and
            Moreno,J.
  TITLE     Splice variants of zinc finger protein 695 mRNA associated to
            ovarian cancer
  JOURNAL   J Ovarian Res 6 (1), 61 (2013)
   PUBMED   24007497
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL512637.18.
            
            On Nov 23, 2018 this sequence version replaced NM_020394.4.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DN995356.1, CN394881.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000339986.8/ ENSP00000341236.7
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-152               AL512637.18        25517-25668         c
            153-315             AL512637.18        17523-17685         c
            316-408             AL512637.18        16959-17051         c
            409-3341            AL512637.18        2934-5866           c
FEATURES             Location/Qualifiers
     source          1..3341
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q44"
     gene            1..3341
                     /gene="ZNF695"
                     /gene_synonym="SBZF3"
                     /note="zinc finger protein 695"
                     /db_xref="GeneID:57116"
                     /db_xref="HGNC:HGNC:30954"
                     /db_xref="MIM:616348"
     exon            1..152
                     /gene="ZNF695"
                     /gene_synonym="SBZF3"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..1697
                     /gene="ZNF695"
                     /gene_synonym="SBZF3"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger protein SBZF3"
                     /codon_start=1
                     /product="zinc finger protein 695 isoform 1"
                     /protein_id="NP_065127.5"
                     /db_xref="CCDS:CCDS44344.1"
                     /db_xref="GeneID:57116"
                     /db_xref="HGNC:HGNC:30954"
                     /db_xref="MIM:616348"
                     /translation="MGLLAFRDVALEFSPEEWECLDPAQRSLYRDVMLENYRNLISLG
                     EDSFNMQFLFHSLAMSKPELIICLEARKEPWNVNTEKTARHSVLSSYLTEDILPEQGL
                     QVSFQKVMLRRYERCCLEKLRLRNDWEIVGEWKGQKASYNGLDLCSATTHSKNFQCNK
                     CVKGFSKFANLNKCKISHTGEKPFKCKECGNVSCMSLIMTQQQRIHIGENPYQCKKCG
                     KAFNECSCFTDCKRIHVGEKHCKCEECNNIFKSCSSLAVVEKNHTEKKTYRCEECGKA
                     FNLCSVLTKHKKIHTGEKPYKCEECGKSFKLFPYLTQHKRIHSREKPYKCEECGKVFK
                     LLSYLTQHRRIHTGEKTFRCEECGKAFNQSSHLTEHRRIHTGEKPYKCEECGKAFTWF
                     SYLIQHKRIHTGQKPYKCEECGKAFTWFSYLTQHKRIHTGEKPYKCDECGKAFNWFSY
                     LTNHKRIHTGEKPYKCEECGKAFGQSSHLSKHKTIHTREKPYKCEECGKAFNHSAQLA
                     VHEKTHT"
     exon            153..315
                     /gene="ZNF695"
                     /gene_synonym="SBZF3"
                     /inference="alignment:Splign:2.1.0"
     exon            316..408
                     /gene="ZNF695"
                     /gene_synonym="SBZF3"
                     /inference="alignment:Splign:2.1.0"
     exon            409..3341
                     /gene="ZNF695"
                     /gene_synonym="SBZF3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2600..2605
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF695"
                     /gene_synonym="SBZF3"
                     /note="hexamer: AATAAA"
     polyA_site      2625
                     /gene="ZNF695"
                     /gene_synonym="SBZF3"
     regulatory      2987..2992
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF695"
                     /gene_synonym="SBZF3"
                     /note="hexamer: AATAAA"
     polyA_site      3014
                     /gene="ZNF695"
                     /gene_synonym="SBZF3"
                     /note="major polyA site"
     regulatory      3313..3318
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF695"
                     /gene_synonym="SBZF3"
                     /note="hexamer: AATAAA"
     polyA_site      3341
                     /gene="ZNF695"
                     /gene_synonym="SBZF3"
ORIGIN      
        1 ctttgtctcc ttgcggccgg cggggtgctg ggttcccgtc tgctgcctct cggagagtcc
       61 cgggtgactg ccgcaggctc catcgccctg tggcctgcag gtattgcgag atttataggg
      121 aggacgctgg gacccccaaa agctgggaaa tgggactatt ggcattcagg gatgtggctc
      181 tagaattctc tccagaggag tgggaatgcc tggacccagc tcagcggagt ttgtataggg
      241 atgtgatgtt agagaactac agaaacctga tctcccttgg tgaggatagc ttcaatatgc
      301 aattcctatt tcacagtctt gctatgtcta agccagaact gatcatctgt ctggaggcaa
      361 ggaaagagcc ctggaacgtg aacacagaga agacagccag acactcagtt ttgtcttctt
      421 atcttactga agacattttg ccagagcagg gcctgcaagt ttcattccaa aaagtgatgc
      481 tgagaagata tgaaagatgt tgtcttgaga aattacgctt aaggaatgac tgggaaattg
      541 tgggtgagtg gaaagggcag aaggcaagtt ataatggact tgacctatgc tcagcaacta
      601 ctcatagcaa aaactttcaa tgcaataaat gtgtgaaagg ttttagtaaa tttgcaaatc
      661 taaataaatg taagataagc catactggag aaaaaccatt caaatgcaaa gaatgtggca
      721 atgtctcttg catgtcttta ataatgactc aacagcagag aatccatatt ggagagaacc
      781 cgtaccaatg taaaaaatgt ggcaaagcct ttaatgagtg ctcatgcttt actgactgta
      841 agagaattca tgttggagag aaacattgca aatgtgaaga atgtaataac atttttaagt
      901 cttgctcaag tcttgctgtt gttgagaaaa atcatactga aaagaaaacc tacagatgtg
      961 aagaatgtgg caaagctttt aacctgtgct cagttcttac taaacataag aaaattcata
     1021 ctggagagaa accatacaaa tgtgaagaat gtggcaaatc ctttaagttg ttcccatacc
     1081 ttactcaaca caagagaatt catagtagag agaaacccta caagtgtgaa gaatgtggca
     1141 aagtctttaa attgttgtca taccttactc aacatagaag aattcatact ggagagaaaa
     1201 ccttccgatg tgaagaatgt ggaaaagcct ttaaccagag ctcacatctg actgaacata
     1261 ggagaattca tactggtgag aaaccataca aatgtgagga atgtggcaaa gcttttacct
     1321 ggttctcata ccttattcag cataagagaa ttcatactgg gcagaaaccc tacaaatgtg
     1381 aggaatgtgg caaagctttt acctggtttt cataccttac tcaacataag agaattcata
     1441 ctggagagaa accctacaaa tgtgatgaat gtggcaaagc ttttaactgg ttttcatatc
     1501 ttactaatca taagagaatt catactggag agaaacccta caaatgtgaa gaatgtggca
     1561 aagcctttgg ccagagctca cacctttcta aacataagac aattcatacc agagagaaac
     1621 catacaagtg tgaggaatgt ggcaaagcct ttaaccactc tgcacaactt gctgtacatg
     1681 agaaaactca tacctgagaa aaaccctaca attctaaaca atatggcata gtctttaata
     1741 cctattcaca acttcacagc agaatatttt tactgaataa gagtgttaca aatgtaatga
     1801 ctgtcaaaag gccatttaca gtctatgagc ctttgagtgc actaaaatgt ttaggctacg
     1861 aacaatacaa atagaccggt tcaacacctc cacttatatc acagctctta ctgtacacag
     1921 aagaatttat actggaggga aaccctccag ttgctcaaac tgtattcaat ttcaaagact
     1981 ttgtattgga gagaaaccct acaaatgtaa taaatgcaga aacaacattt gttcaaaaaa
     2041 tatacctcag aaaacaccag agtgttcaca ctaaaaactg ttttacagat gcagtaaatg
     2101 tgaaaaaatg tctaatcaaa aattacatca aaacacatcc aagaattcat agtaaaaagc
     2161 actaagtcac tgacactttc agacattact gtaaatctga gtgttggtta tagagaataa
     2221 ttcaaagtta agttaaagta agtaggagat tcaccttttg gggaagttat aattacattt
     2281 caagtatacc ttttggtgcc aggcacggtg gctctttcct atagttgctg cacttttgga
     2341 tgccgaggtc gggggattgc ttgagcccag gagtttggga ccaggctggg caacatggca
     2401 aaacctcatc tctacaaaaa gtaaaataaa agccaggctt ggtggcacat gcctgttgtc
     2461 ccagctactt ggaaggctca ggtgggagga ttgcttgagc ctggaggttg aggatgcagt
     2521 gagctgctat ctggcaactt cactcctgcc tgggcaacag agcaagaccc tttctcaata
     2581 ataataataa caacataata ataaagtata ctcggtgcac tgaaagagtt ttagcttttt
     2641 tgaaaatcac atatttatgt aattcaagtc ttaaatcact tgataccatg ccttcatttc
     2701 tagtgtttat gtgaaggcat gaggcctact gttgctacat gaaagctgtg agagtttctt
     2761 ctatattcgg gtgggtgttg ttcatatcct tttctttgga agattatgga cattgcattg
     2821 taagcttcct gaagaaattt aactggagag gctctttgta cttgtcttat aatagggttg
     2881 taagtgattc atgagatagg tcttcagagt actattctgc attatattta agaaagaaac
     2941 atttgagttt tacaagtcag ttgtttttcc tattgcacat taaggtaata aaattcagtg
     3001 gattttgaaa tgctcttttt agactgtttg aacttaattt gttttaataa gacattgttt
     3061 taatgtcttt ggaccgttgt acattaagtg atgcgtatcc taccaccaac gttaacctat
     3121 ctcaccttag ttacggttgt aggtaacaaa tggtaacaat acaatagtgg gtaacatggt
     3181 ggaatagtat ctctaatgat cccttctccc agtggcatta aacttcaaat aatttgaaaa
     3241 atattgttcc cacacgttac accttcattc tgtttgctct ttttgtaatg acagtgtcat
     3301 tattaaggct ataataaagc ctatatagga ttataatcaa a
//
