LOCUS       NM_152373               2019 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 684 (ZNF684), mRNA.
ACCESSION   NM_152373
VERSION     NM_152373.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2019)
  AUTHORS   Yin,Y., Morgunova,E., Jolma,A., Kaasinen,E., Sahu,B.,
            Khund-Sayeed,S., Das,P.K., Kivioja,T., Dave,K., Zhong,F.,
            Nitta,K.R., Taipale,M., Popov,A., Ginno,P.A., Domcke,S., Yan,J.,
            Schubeler,D., Vinson,C. and Taipale,J.
  TITLE     Impact of cytosine methylation on DNA binding specificities of
            human transcription factors
  JOURNAL   Science 356 (6337) (2017)
   PUBMED   28473536
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK094072.1, BC111463.1 and BG116229.1.
            
            On Nov 22, 2018 this sequence version replaced NM_152373.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK094072.1, SRR3476690.362201.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000372699.8/ ENSP00000361784.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-993               AK094072.1         77-1069
            994-1823            BC111463.1         409-1238
            1824-2019           BG116229.1         1-196
FEATURES             Location/Qualifiers
     source          1..2019
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p34.2"
     gene            1..2019
                     /gene="ZNF684"
                     /note="zinc finger protein 684"
                     /db_xref="GeneID:127396"
                     /db_xref="HGNC:HGNC:28418"
     exon            1..151
                     /gene="ZNF684"
                     /inference="alignment:Splign:2.1.0"
     exon            152..190
                     /gene="ZNF684"
                     /inference="alignment:Splign:2.1.0"
     CDS             176..1312
                     /gene="ZNF684"
                     /note="hypothetical protein MGC27466"
                     /codon_start=1
                     /product="zinc finger protein 684"
                     /protein_id="NP_689586.3"
                     /db_xref="CCDS:CCDS454.1"
                     /db_xref="GeneID:127396"
                     /db_xref="HGNC:HGNC:28418"
                     /translation="MISFQESVTFQDVAVDFTAEEWQLLDCAERTLYWDVMLENYRNL
                     ISVGCPITKTKVILKVEQGQEPWMVEGANPHESSPESDYPLVDEPGKHRESKDNFLKS
                     VLLTFNKILTMERIHHYNMSTSLNPMRKKSYKSFEKCLPPNLDLLKYNRSYTVENAYE
                     CSECGKAFKKKFHFIRHEKNHTRKKPFECNDCGKAYSRKAHLATHQKIHNGERPFVCN
                     DCGKAFMHKAQLVVHQRLHTGEKPYECSQCGKTFTWNSSFNQHVKSHTLEKSFECKEC
                     GKTFRYSSSLYKHSRFHTGEKPYQCIICGKAFGNTSVLVTHQRIHTGEKPYSCIECGK
                     AFIKKSHLLRHQITHTGEKPYECNRCGKAFSQKSNLIVHQKIHT"
     exon            191..317
                     /gene="ZNF684"
                     /inference="alignment:Splign:2.1.0"
     exon            318..413
                     /gene="ZNF684"
                     /inference="alignment:Splign:2.1.0"
     exon            414..2019
                     /gene="ZNF684"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2002..2007
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF684"
                     /note="hexamer: AATAAT"
     polyA_site      2019
                     /gene="ZNF684"
                     /note="major polyA site"
ORIGIN      
        1 acacgcgtag taggacggta gccggtattc aatcttcaaa tcagcgccgc gggaagtgcg
       61 ggcgggtgtt gctcccctgt ctctggacga cgctgtgact gatcccaggc ttggagccgg
      121 agctgcgagc gaggcagtga aagggtggca gatttctgtg taagagctgc agaaaatgat
      181 cagcttccag gaatcagtga cattccagga tgtggctgtg gatttcactg cagaggagtg
      241 gcagctgctt gattgtgctg agagaaccct gtattgggat gtgatgttgg agaactatag
      301 aaacctcatc tcagtgggat gtccaattac caaaacaaaa gtgatcctca aggtagagca
      361 aggacaagag ccatggatgg tggagggagc gaatccacac gagagctctc cagaatctga
      421 ctacccactt gttgatgaac cagggaagca tcgggaaagc aaagacaatt ttttgaagtc
      481 agttttgctc acattcaata aaattctgac tatggagaga atccaccatt ataatatgag
      541 cacaagtctt aatccaatga gaaaaaaatc atataaatcg tttgagaagt gtttgccacc
      601 taatttagac ttacttaaat ataatagaag ttatactgta gaaaacgctt atgaatgcag
      661 tgaatgcggg aaagccttca aaaagaagtt tcatttcatt agacatgaaa aaaatcatac
      721 aaggaaaaaa ccttttgaat gcaatgactg tggaaaagcc tatagcagga aggcacacct
      781 tgcaactcat cagaaaattc ataatggaga gagacccttt gtgtgcaatg attgtgggaa
      841 ggcgtttatg cataaagccc aactcgtggt ccaccagaga cttcacactg gagagaagcc
      901 ttatgagtgc agtcaatgtg ggaaaacatt cacttggaac tcctcattta atcaacacgt
      961 gaaatctcat acacttgaga agtcatttga atgtaaggaa tgtgggaaaa ccttcaggta
     1021 tagttcatcc ctttataaac attccagatt tcatacagga gagaaaccct accagtgtat
     1081 catatgtggc aaagcttttg gcaacacatc cgtgcttgtt acacaccaaa gaattcatac
     1141 aggagagaaa ccttacagtt gtattgaatg tggcaaagcc ttcatcaaga agtcccatct
     1201 cctcagacat cagataactc atacaggaga gaagccctat gaatgtaaca gatgtgggaa
     1261 agcattttcc cagaagtcaa atcttattgt acatcagaaa attcatacat aatattcact
     1321 ttatgaatat gagaaggcct tattaaatat ttgctaaatc ttattaaata ctaaagaatt
     1381 catggtgaga agtctacaat ttaaatgaat ttggaagagt agattcccat aaaaaacaac
     1441 caatgccaat catgttctgg aagtgataat aaacttttta cagaaaatat gacagaaaac
     1501 aactataaat aatagagcat aaagcttgga aagtaagcat aacttaaaaa atcaaagaac
     1561 cagtgaaaac tacatttgcc attcctgact tttaattttt ataataaaat aattatgcaa
     1621 gtgtgagttt aaaatatatg cttatacatt atattaaagt atgcctatta acagtttctg
     1681 cagtaaataa cattttttct tccagtctca acatacataa ttaatcaagt gagaaaatgt
     1741 gttttaatat gtcatatgaa tttcagtgat attttcatcc atttgctggc acttttaatg
     1801 ggcatgacag tgtttctgaa tctgagtctc ctttaattat acaagtgaag acttcttatt
     1861 aaaattaata taaagatatt ttcctatgta tgtaaatacc agaacaaaaa acaagacact
     1921 aattgaggag agaaaggcac ttgtattctg tattacagta agtattcagt tgaggaaaag
     1981 aattatttaa atatgtaaat aaataatttg cacttcaaa
//
