LOCUS       NM_152437               4312 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 664 (ZNF664), transcript variant
            1, mRNA.
ACCESSION   NM_152437
VERSION     NM_152437.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4312)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 4312)
  AUTHORS   Zhang,T.X., Haller,G., Lin,P., Alvarado,D.M., Hecht,J.T.,
            Blanton,S.H., Stephens Richards,B., Rice,J.P., Dobbs,M.B. and
            Gurnett,C.A.
  TITLE     Genome-wide association study identifies new disease loci for
            isolated clubfoot
  JOURNAL   J Med Genet 51 (5), 334-339 (2014)
   PUBMED   24667120
REFERENCE   3  (bases 1 to 4312)
  AUTHORS   Wu,Y., Gao,H., Li,H., Tabara,Y., Nakatochi,M., Chiu,Y.F.,
            Park,E.J., Wen,W., Adair,L.S., Borja,J.B., Cai,Q., Chang,Y.C.,
            Chen,P., Croteau-Chonka,D.C., Fogarty,M.P., Gan,W., He,C.T.,
            Hsiung,C.A., Hwu,C.M., Ichihara,S., Igase,M., Jo,J., Kato,N.,
            Kawamoto,R., Kuzawa,C.W., Lee,J.J., Liu,J., Lu,L., McDade,T.W.,
            Osawa,H., Sheu,W.H., Teo,Y., Vadlamudi,S., Van Dam,R.M., Wang,Y.,
            Xiang,Y.B., Yamamoto,K., Ye,X., Young,T.L., Zheng,W., Zhu,J.,
            Shu,X.O., Shin,C., Jee,S.H., Chuang,L.M., Miki,T., Yokota,M.,
            Lin,X., Mohlke,K.L. and Tai,E.S.
  TITLE     A meta-analysis of genome-wide association studies for adiponectin
            levels in East Asians identifies a novel locus near WDR11-FGFR2
  JOURNAL   Hum Mol Genet 23 (4), 1108-1119 (2014)
   PUBMED   24105470
REFERENCE   4  (bases 1 to 4312)
  AUTHORS   Willer,C.J., Schmidt,E.M., Sengupta,S., Peloso,G.M., Gustafsson,S.,
            Kanoni,S., Ganna,A., Chen,J., Buchkovich,M.L., Mora,S.,
            Beckmann,J.S., Bragg-Gresham,J.L., Chang,H.Y., Demirkan,A., Den
            Hertog,H.M., Do,R., Donnelly,L.A., Ehret,G.B., Esko,T.,
            Feitosa,M.F., Ferreira,T., Fischer,K., Fontanillas,P., Fraser,R.M.,
            Freitag,D.F., Gurdasani,D., Heikkila,K., Hypponen,E., Isaacs,A.,
            Jackson,A.U., Johansson,A., Johnson,T., Kaakinen,M., Kettunen,J.,
            Kleber,M.E., Li,X., Luan,J., Lyytikainen,L.P., Magnusson,P.K.E.,
            Mangino,M., Mihailov,E., Montasser,M.E., Muller-Nurasyid,M.,
            Nolte,I.M., O'Connell,J.R., Palmer,C.D., Perola,M., Petersen,A.K.,
            Sanna,S., Saxena,R., Service,S.K., Shah,S., Shungin,D., Sidore,C.,
            Song,C., Strawbridge,R.J., Surakka,I., Tanaka,T., Teslovich,T.M.,
            Thorleifsson,G., Van den Herik,E.G., Voight,B.F., Volcik,K.A.,
            Waite,L.L., Wong,A., Wu,Y., Zhang,W., Absher,D., Asiki,G.,
            Barroso,I., Been,L.F., Bolton,J.L., Bonnycastle,L.L., Brambilla,P.,
            Burnett,M.S., Cesana,G., Dimitriou,M., Doney,A.S.F., Doring,A.,
            Elliott,P., Epstein,S.E., Ingi Eyjolfsson,G., Gigante,B.,
            Goodarzi,M.O., Grallert,H., Gravito,M.L., Groves,C.J., Hallmans,G.,
            Hartikainen,A.L., Hayward,C., Hernandez,D., Hicks,A.A., Holm,H.,
            Hung,Y.J., Illig,T., Jones,M.R., Kaleebu,P., Kastelein,J.J.P.,
            Khaw,K.T., Kim,E., Klopp,N., Komulainen,P., Kumari,M.,
            Langenberg,C., Lehtimaki,T., Lin,S.Y., Lindstrom,J., Loos,R.J.F.,
            Mach,F., McArdle,W.L., Meisinger,C., Mitchell,B.D., Muller,G.,
            Nagaraja,R., Narisu,N., Nieminen,T.V.M., Nsubuga,R.N., Olafsson,I.,
            Ong,K.K., Palotie,A., Papamarkou,T., Pomilla,C., Pouta,A.,
            Rader,D.J., Reilly,M.P., Ridker,P.M., Rivadeneira,F., Rudan,I.,
            Ruokonen,A., Samani,N., Scharnagl,H., Seeley,J., Silander,K.,
            Stancakova,A., Stirrups,K., Swift,A.J., Tiret,L.,
            Uitterlinden,A.G., van Pelt,L.J., Vedantam,S., Wainwright,N.,
            Wijmenga,C., Wild,S.H., Willemsen,G., Wilsgaard,T., Wilson,J.F.,
            Young,E.H., Zhao,J.H., Adair,L.S., Arveiler,D., Assimes,T.L.,
            Bandinelli,S., Bennett,F., Bochud,M., Boehm,B.O., Boomsma,D.I.,
            Borecki,I.B., Bornstein,S.R., Bovet,P., Burnier,M., Campbell,H.,
            Chakravarti,A., Chambers,J.C., Chen,Y.I., Collins,F.S.,
            Cooper,R.S., Danesh,J., Dedoussis,G., de Faire,U., Feranil,A.B.,
            Ferrieres,J., Ferrucci,L., Freimer,N.B., Gieger,C., Groop,L.C.,
            Gudnason,V., Gyllensten,U., Hamsten,A., Harris,T.B., Hingorani,A.,
            Hirschhorn,J.N., Hofman,A., Hovingh,G.K., Hsiung,C.A.,
            Humphries,S.E., Hunt,S.C., Hveem,K., Iribarren,C., Jarvelin,M.R.,
            Jula,A., Kahonen,M., Kaprio,J., Kesaniemi,A., Kivimaki,M.,
            Kooner,J.S., Koudstaal,P.J., Krauss,R.M., Kuh,D., Kuusisto,J.,
            Kyvik,K.O., Laakso,M., Lakka,T.A., Lind,L., Lindgren,C.M.,
            Martin,N.G., Marz,W., McCarthy,M.I., McKenzie,C.A., Meneton,P.,
            Metspalu,A., Moilanen,L., Morris,A.D., Munroe,P.B., Njolstad,I.,
            Pedersen,N.L., Power,C., Pramstaller,P.P., Price,J.F., Psaty,B.M.,
            Quertermous,T., Rauramaa,R., Saleheen,D., Salomaa,V.,
            Sanghera,D.K., Saramies,J., Schwarz,P.E.H., Sheu,W.H.,
            Shuldiner,A.R., Siegbahn,A., Spector,T.D., Stefansson,K.,
            Strachan,D.P., Tayo,B.O., Tremoli,E., Tuomilehto,J., Uusitupa,M.,
            van Duijn,C.M., Vollenweider,P., Wallentin,L., Wareham,N.J.,
            Whitfield,J.B., Wolffenbuttel,B.H.R., Ordovas,J.M., Boerwinkle,E.,
            Palmer,C.N.A., Thorsteinsdottir,U., Chasman,D.I., Rotter,J.I.,
            Franks,P.W., Ripatti,S., Cupples,L.A., Sandhu,M.S., Rich,S.S.,
            Boehnke,M., Deloukas,P., Kathiresan,S., Mohlke,K.L., Ingelsson,E.
            and Abecasis,G.R.
  CONSRTM   Global Lipids Genetics Consortium
  TITLE     Discovery and refinement of loci associated with lipid levels
  JOURNAL   Nat Genet 45 (11), 1274-1283 (2013)
   PUBMED   24097068
REFERENCE   5  (bases 1 to 4312)
  AUTHORS   Fox,C.S., Liu,Y., White,C.C., Feitosa,M., Smith,A.V.,
            Heard-Costa,N., Lohman,K., Johnson,A.D., Foster,M.C.,
            Greenawalt,D.M., Griffin,P., Ding,J., Newman,A.B., Tylavsky,F.,
            Miljkovic,I., Kritchevsky,S.B., Launer,L., Garcia,M.,
            Eiriksdottir,G., Carr,J.J., Gudnason,V., Harris,T.B., Cupples,L.A.
            and Borecki,I.B.
  CONSRTM   GIANT Consortium; MAGIC Consortium; GLGC Consortium
  TITLE     Genome-wide association for abdominal subcutaneous and visceral
            adipose reveals a novel locus for visceral fat in women
  JOURNAL   PLoS Genet 8 (5), e1002695 (2012)
   PUBMED   22589738
REFERENCE   6  (bases 1 to 4312)
  AUTHORS   Shi,Y., Li,Y., Zhang,D., Zhang,H., Li,Y., Lu,F., Liu,X., He,F.,
            Gong,B., Cai,L., Li,R., Liao,S., Ma,S., Lin,H., Cheng,J., Zheng,H.,
            Shan,Y., Chen,B., Hu,J., Jin,X., Zhao,P., Chen,Y., Zhang,Y.,
            Lin,Y., Li,X., Fan,Y., Yang,H., Wang,J. and Yang,Z.
  TITLE     Exome sequencing identifies ZNF644 mutations in high myopia
  JOURNAL   PLoS Genet 7 (6), e1002084 (2011)
   PUBMED   21695231
REFERENCE   7  (bases 1 to 4312)
  AUTHORS   Teslovich,T.M., Musunuru,K., Smith,A.V., Edmondson,A.C.,
            Stylianou,I.M., Koseki,M., Pirruccello,J.P., Ripatti,S.,
            Chasman,D.I., Willer,C.J., Johansen,C.T., Fouchier,S.W., Isaacs,A.,
            Peloso,G.M., Barbalic,M., Ricketts,S.L., Bis,J.C., Aulchenko,Y.S.,
            Thorleifsson,G., Feitosa,M.F., Chambers,J., Orho-Melander,M.,
            Melander,O., Johnson,T., Li,X., Guo,X., Li,M., Shin Cho,Y., Jin
            Go,M., Jin Kim,Y., Lee,J.Y., Park,T., Kim,K., Sim,X., Twee-Hee
            Ong,R., Croteau-Chonka,D.C., Lange,L.A., Smith,J.D., Song,K., Hua
            Zhao,J., Yuan,X., Luan,J., Lamina,C., Ziegler,A., Zhang,W.,
            Zee,R.Y., Wright,A.F., Witteman,J.C., Wilson,J.F., Willemsen,G.,
            Wichmann,H.E., Whitfield,J.B., Waterworth,D.M., Wareham,N.J.,
            Waeber,G., Vollenweider,P., Voight,B.F., Vitart,V.,
            Uitterlinden,A.G., Uda,M., Tuomilehto,J., Thompson,J.R., Tanaka,T.,
            Surakka,I., Stringham,H.M., Spector,T.D., Soranzo,N., Smit,J.H.,
            Sinisalo,J., Silander,K., Sijbrands,E.J., Scuteri,A., Scott,J.,
            Schlessinger,D., Sanna,S., Salomaa,V., Saharinen,J., Sabatti,C.,
            Ruokonen,A., Rudan,I., Rose,L.M., Roberts,R., Rieder,M.,
            Psaty,B.M., Pramstaller,P.P., Pichler,I., Perola,M., Penninx,B.W.,
            Pedersen,N.L., Pattaro,C., Parker,A.N., Pare,G., Oostra,B.A.,
            O'Donnell,C.J., Nieminen,M.S., Nickerson,D.A., Montgomery,G.W.,
            Meitinger,T., McPherson,R., McCarthy,M.I., McArdle,W., Masson,D.,
            Martin,N.G., Marroni,F., Mangino,M., Magnusson,P.K., Lucas,G.,
            Luben,R., Loos,R.J., Lokki,M.L., Lettre,G., Langenberg,C.,
            Launer,L.J., Lakatta,E.G., Laaksonen,R., Kyvik,K.O., Kronenberg,F.,
            Konig,I.R., Khaw,K.T., Kaprio,J., Kaplan,L.M., Johansson,A.,
            Jarvelin,M.R., Janssens,A.C., Ingelsson,E., Igl,W., Kees
            Hovingh,G., Hottenga,J.J., Hofman,A., Hicks,A.A., Hengstenberg,C.,
            Heid,I.M., Hayward,C., Havulinna,A.S., Hastie,N.D., Harris,T.B.,
            Haritunians,T., Hall,A.S., Gyllensten,U., Guiducci,C., Groop,L.C.,
            Gonzalez,E., Gieger,C., Freimer,N.B., Ferrucci,L., Erdmann,J.,
            Elliott,P., Ejebe,K.G., Doring,A., Dominiczak,A.F., Demissie,S.,
            Deloukas,P., de Geus,E.J., de Faire,U., Crawford,G., Collins,F.S.,
            Chen,Y.D., Caulfield,M.J., Campbell,H., Burtt,N.P.,
            Bonnycastle,L.L., Boomsma,D.I., Boekholdt,S.M., Bergman,R.N.,
            Barroso,I., Bandinelli,S., Ballantyne,C.M., Assimes,T.L.,
            Quertermous,T., Altshuler,D., Seielstad,M., Wong,T.Y., Tai,E.S.,
            Feranil,A.B., Kuzawa,C.W., Adair,L.S., Taylor,H.A. Jr.,
            Borecki,I.B., Gabriel,S.B., Wilson,J.G., Holm,H.,
            Thorsteinsdottir,U., Gudnason,V., Krauss,R.M., Mohlke,K.L.,
            Ordovas,J.M., Munroe,P.B., Kooner,J.S., Tall,A.R., Hegele,R.A.,
            Kastelein,J.J., Schadt,E.E., Rotter,J.I., Boerwinkle,E.,
            Strachan,D.P., Mooser,V., Stefansson,K., Reilly,M.P., Samani,N.J.,
            Schunkert,H., Cupples,L.A., Sandhu,M.S., Ridker,P.M., Rader,D.J.,
            van Duijn,C.M., Peltonen,L., Abecasis,G.R., Boehnke,M. and
            Kathiresan,S.
  TITLE     Biological, clinical and population relevance of 95 loci for blood
            lipids
  JOURNAL   Nature 466 (7307), 707-713 (2010)
   PUBMED   20686565
REFERENCE   8  (bases 1 to 4312)
  AUTHORS   Rivolta,M.N., Negrini,C. and Wilcox,E.R.
  TITLE     A novel zinc finger gene preferentially expressed in the retina and
            the organ of Corti localizes to human chromosome 12q24.3
  JOURNAL   Biochim Biophys Acta 1306 (2-3), 127-132 (1996)
   PUBMED   8634327
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA304849.1, BX647762.1, AK056034.1, BC051696.1, AC068790.36 and
            BQ185193.1.
            
            On Nov 23, 2018 this sequence version replaced NM_152437.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DA326356.1, SRR1803616.40783.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000337815.9/ ENSP00000337320.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-80                DA304849.1         1-80
            81-287              BX647762.1         1-207
            288-653             AK056034.1         195-560
            654-1443            BC051696.1         584-1373
            1444-2961           BX647762.1         1364-2881
            2962-3960           AC068790.36        69994-70992
            3961-4312           BQ185193.1         30-381              c
FEATURES             Location/Qualifiers
     source          1..4312
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q24.31"
     gene            1..4312
                     /gene="ZNF664"
                     /gene_synonym="ZFOC1; ZNF176"
                     /note="zinc finger protein 664"
                     /db_xref="GeneID:144348"
                     /db_xref="HGNC:HGNC:25406"
                     /db_xref="MIM:617890"
     exon            1..138
                     /gene="ZNF664"
                     /gene_synonym="ZFOC1; ZNF176"
                     /inference="alignment:Splign:2.1.0"
     exon            139..273
                     /gene="ZNF664"
                     /gene_synonym="ZFOC1; ZNF176"
                     /inference="alignment:Splign:2.1.0"
     exon            274..369
                     /gene="ZNF664"
                     /gene_synonym="ZFOC1; ZNF176"
                     /inference="alignment:Splign:2.1.0"
     exon            370..430
                     /gene="ZNF664"
                     /gene_synonym="ZFOC1; ZNF176"
                     /inference="alignment:Splign:2.1.0"
     exon            431..4312
                     /gene="ZNF664"
                     /gene_synonym="ZFOC1; ZNF176"
                     /inference="alignment:Splign:2.1.0"
     CDS             1030..1815
                     /gene="ZNF664"
                     /gene_synonym="ZFOC1; ZNF176"
                     /note="zinc finger Organ of Corti 1; zinc finger protein
                     176; zinc finger protein from organ of Corti"
                     /codon_start=1
                     /product="zinc finger protein 664"
                     /protein_id="NP_689650.1"
                     /db_xref="CCDS:CCDS9257.1"
                     /db_xref="GeneID:144348"
                     /db_xref="HGNC:HGNC:25406"
                     /db_xref="MIM:617890"
                     /translation="MIYKCPMCREFFSERADLFMHQKIHTAEKPHKCDKCDKGFFHIS
                     ELHIHWRDHTGEKVYKCDDCGKDFSTTTKLNRHKKIHTVEKPYKCYECGKAFNWSSHL
                     QIHMRVHTGEKPYVCSECGRGFSNSSNLCMHQRVHTGEKPFKCEECGKAFRHTSSLCM
                     HQRVHTGEKPYKCYECGKAFSQSSSLCIHQRVHTGEKPYRCCGCGKAFSQSSSLCIHQ
                     RVHTGEKPFKCDECGKAFSQSTSLCIHQRVHTKERNHLKISVI"
     regulatory      4290..4295
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF664"
                     /gene_synonym="ZFOC1; ZNF176"
                     /note="hexamer: AATAAA"
     polyA_site      4312
                     /gene="ZNF664"
                     /gene_synonym="ZFOC1; ZNF176"
                     /note="major polyA site"
ORIGIN      
        1 gcgctgtccc ccggaggcgt ctgggtgtgc ggagcgcgcg cgcgcgcggc tcggaggcgc
       61 acctgtgagg tgtccctgag gagagggagg tgggtgcgcg gcgcccgcgg cctggggcgc
      121 tgactcccct cacttggagg cgccctgcgt ccggcagagg aggcgagcat cccgctcagg
      181 tgatgaggaa cccctcgcgc acccagcgca gaaggctgct gccgccggac gcctccattg
      241 tttgaccaca acaagggccg gattctcacc cagcaggatc ctaaggcctt tgtagtcctt
      301 cagccactgt gggccctgcc tctgcctgtt cttctggaat gtcttggggg ttttgatcct
      361 gtcactgtga cctgcaaatc caagagacac atctttggaa gataagagag cttcttcaag
      421 accaaaaaag gagacggcat gatacccatg tagggaattc cccaaagcag ggcttgccat
      481 acctggaccc cgaggagcct gcttgctgga aaggctttcc tgtctgatgt gcaggaggca
      541 gaatgccaaa ctgactcttc aaggggcaac tgcaggggct cgagaccagc cagcagtatc
      601 tcatccttcg atacagggga tatactgtac agtccttttt ctagaagtga gacatacaag
      661 attactctac aagaggaaga ttccaggggc tcaaaaacgc aaaggtttgc actttgagag
      721 ccccttggaa tgttgacaac tcaggatcta aaacaaagtt ctgtgttaat gagttacaga
      781 attcacgtgg aagtcaatgt cactttataa tcgataataa tactgagtga ggaacactat
      841 gcaggaagaa accttccgta gaaagacagg cagggaaaag cttaggctga ccttaaactt
      901 acctaataga gcaagcctga gatagactgc caaaatggcc aaataagaga ctctatgaaa
      961 taacagtctt gtaactgtag taatcataag gaaattttct ccttgaaatc acgataccaa
     1021 ataggaaaaa tgatctacaa gtgccccatg tgtagggaat ttttctctga gagagcagat
     1081 ctttttatgc atcagaaaat tcacacagct gagaagcccc ataaatgtga caagtgtgat
     1141 aagggtttct ttcatatatc agaacttcat attcattgga gagaccatac aggagagaag
     1201 gtctataaat gtgatgattg tggtaaggat tttagcacta caacaaaact taatagacat
     1261 aagaaaatcc acacagtgga gaagccctat aaatgttacg agtgtggcaa agccttcaat
     1321 tggagctccc atcttcaaat tcatatgaga gttcatacag gtgagaaacc gtatgtctgt
     1381 agtgagtgtg gaaggggctt tagtaatagt tcaaaccttt gcatgcatca gagagtccac
     1441 accggagaga agccctttaa atgtgaagag tgtgggaagg ccttcaggca cacctccagc
     1501 ctctgcatgc atcaaagagt ccacacagga gagaaaccct ataaatgtta tgagtgtggg
     1561 aaggcgttca gtcagagttc gagcctctgc atccaccaga gagtccacac tggagagaaa
     1621 ccctatagat gttgtggatg tgggaaggcc ttcagtcaga gttcgagcct gtgcatccac
     1681 cagagagtcc acacaggaga gaaacctttc aaatgtgatg agtgcggaaa ggccttcagt
     1741 cagagtacga gcctctgcat ccaccagaga gtccacacaa aggagagaaa ccatctcaaa
     1801 atatcagtta tataaaacgt tttgctaaga gtttaaaatc ttaaaaccca taagtgccac
     1861 taggaaggaa accctgtata tacctacatt gacccaagaa atatttacgc aatccctagc
     1921 agaacattgt ttctgaggag gcatatgtga gattgatttg ttggttcatg ccaagtgtgt
     1981 tccacaggtt gactttgaat gtggacctct gagcatccac gcaggatggc tctcaggtcc
     2041 cagtcacaga cgtcgcttcc tgggattcca gcacgatgcc tccatagttg aaagactaca
     2101 caaaaagcca caatcattgc ccggcctcct gagtcacctt ctatctatac tttgcttaaa
     2161 agctatccca gatactcccc cttgaggagc tcatgccctt ccttcctctt tattcgagca
     2221 tactggcaat gcattggaaa acagacagct cccactaaga tcacgttctg gtatttctga
     2281 ggttaacact tgatttagcc cctacatatc tttccatata tcctattatt tctgaatata
     2341 tgtcctcaaa atccccataa atatccatcc cttcctagat ggcattaact ttcattttag
     2401 attttaggtg actcataatt cccattcact tagcctatca gaaaagtcat tggcagacat
     2461 atatgtcctt gaaccttttt tatttgtgtg gattctgctc atcactgtct ctgttagact
     2521 tattttgtag tggctgcatc acatattttt cacttgaatt tttttggaaa tagctgaatg
     2581 taaatagcag ggaggaagaa gcaagcaaag tgagagcttt tcttcatcca gaattgccct
     2641 ctgggctcct ttggtaacag atggagctcc ttcctagcta gggagacctt atgagaagtg
     2701 gatggtagga ggagtcacta atgtttcaat ctctatttct gtaatcttgg gcaataatgc
     2761 ataggagttc ttgatacccc ttcattgatt actgtgtatc agttctttgt taggcatgaa
     2821 cgtctttatt aatccatcat tcttttcttc attcaacaaa tatgtattga acacctccta
     2881 tatgccaggc actgtgctag gtgctgggaa taccactgat gagacagaca aggtccctac
     2941 tcttgtggag tttacttctg gtggaggaga cagatgataa gtaaacaaat aaataatgta
     3001 gtttgagata gtgattaagt gctatgaaga aaataaacta gggtgatgat tttagtggtg
     3061 gggtggggtg ggggtggggt gacattagct agtggtcagg gaggcctttc cgcggtggga
     3121 tgttgagctg aggccggagg agaagtagca gtcgctggca gagcacacag gctgctctgg
     3181 gggatgagct ggtgcgttta aggaacaggc cagcactggc attcgcaagc agtggggaag
     3241 gggagagatg ccgaggtggt cagtatcctg actttcagag gccttttttt gtttgtttta
     3301 atttttgcta gattgatatt aaaaactcat gtggaggaac tcaaggaatg tttagaagac
     3361 caaaagtccc caatgacagg aacaaaagca accaattttt aactttctct tctcattcct
     3421 gttttcattg atttcccaca tgtagtcctt ttgctcagga agtctttggg gaaattaagg
     3481 atctttgaag ctctgaaata ggtgatcagg ttagtggtgt ctgtcagctg tctaagaggt
     3541 tggaaaatga actactcaag atagtcacga aaatactgaa agtttgattt ttctttccat
     3601 atttgaatta attttttctg tttgactgga aggggttttt gtataactaa aacctcagcg
     3661 cataaaggag atttaaaagg agcacatgat ttagtgggtg ggccatgaaa ctagagatgg
     3721 gatttggggg tgaatttgtc aatatctgga ttttaatcca gacatctctg ctaacaagcc
     3781 tttggtaagt cacttcagat acttttcctc ctttttacaa agagagggct ggcttagtta
     3841 tttgccaaag ccccttccag gcctgaattc cacaagtacg atttactgta gtgtcttatc
     3901 actctttcat gtcacaatag cgtggagcat tagagaaaag cctagacttt tagttgatag
     3961 ccagttgaaa tatcattgat agaattttag ttttaggaaa aattggtttg atttctagct
     4021 ttattactat taggtatgtg agcttgggca aatcgcttaa tctttgagtc tagttttctc
     4081 tcaaaatgag aacattaggc taaatgattt ccgagtttcc agctagtcct agagttctat
     4141 atttctacat agttgaatta ttttatcatg ctgttgctgg ggaatatgac taaccctttt
     4201 gaagctacta attttatgtc gagctttaaa gtccataatt gttatcttca gaaaatatta
     4261 tttgacctac agtatgtcca aatcaattta ataaaatcgc tttataacag gg
//
