LOCUS       NM_033113               3562 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 628 (ZNF628), mRNA.
ACCESSION   NM_033113 XM_058964
VERSION     NM_033113.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3562)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 3562)
  AUTHORS   Chen,G.Y., Muramatsu,H., Ichihara-Tanaka,K. and Muramatsu,T.
  TITLE     ZEC, a zinc finger protein with novel binding specificity and
            transcription regulatory activity
  JOURNAL   Gene 340 (1), 71-81 (2004)
   PUBMED   15556296
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC089449.1, AC008735.9 and BC016036.2.
            
            On Nov 22, 2018 this sequence version replaced NM_033113.2.
            
            Summary: Zinc finger proteins (ZNFs), which bind nucleic acids,
            perform many key functions, the most important of which is
            regulating transcription. See ZNF91 (MIM 603971) for general
            information on ZNFs.[supplied by OMIM, Mar 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089449.1, HY017231.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000598519.2/ ENSP00000469591.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-967               BC089449.1         286-1252
            968-2980            AC008735.9         192441-194453       c
            2981-3558           BC089449.1         3266-3843
            3559-3562           BC016036.2         1152-1155
FEATURES             Location/Qualifiers
     source          1..3562
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.42"
     gene            1..3562
                     /gene="ZNF628"
                     /gene_synonym="ZEC; Zfp628"
                     /note="zinc finger protein 628"
                     /db_xref="GeneID:89887"
                     /db_xref="HGNC:HGNC:28054"
                     /db_xref="MIM:610671"
     exon            1..191
                     /gene="ZNF628"
                     /gene_synonym="ZEC; Zfp628"
                     /inference="alignment:Splign:2.1.0"
     exon            192..275
                     /gene="ZNF628"
                     /gene_synonym="ZEC; Zfp628"
                     /inference="alignment:Splign:2.1.0"
     CDS             269..3448
                     /gene="ZNF628"
                     /gene_synonym="ZEC; Zfp628"
                     /note="zinc finger protein Zec"
                     /codon_start=1
                     /product="zinc finger protein 628"
                     /protein_id="NP_149104.3"
                     /db_xref="CCDS:CCDS33116.3"
                     /db_xref="GeneID:89887"
                     /db_xref="HGNC:HGNC:28054"
                     /db_xref="MIM:610671"
                     /translation="MSGVMVGSHADMAPASTAEGAGEKPGPAAPAPAAQYECGECGKS
                     FRWSSRLLHHQRTHTGERPYKCPDCPKAFKGSSALLYHQRGHTGERPYQCPDCPKAFK
                     RSSLLQIHRSVHTGLRAFICGQCGLAFKWSSHYQYHLRQHTGERPYPCPDCPKAFKNS
                     SSLRRHRHVHTGERPYTCGVCGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSN
                     LLLHQRTHGAAPAPGTASAAPPPQSREPGKVFVCDAYLQRHLQPHSPPAPPAPPPPPP
                     PVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEHQPCPGPDAAPQPQEAPAEAPK
                     ADQPPSPLPQPPPPAAAPAPGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFRCGSCD
                     GSFPQLASLLAHQQCHVEEAAAGRPPPQAEAAEVTCPQEPLAPAAPVPPPPPSAPASA
                     ERPYKCAECGKSFKGSSGLRYHLRDHTGERPYQCGECGKAFKRSSLLAIHQRVHTGLR
                     AFTCGQCGLTFKWSSHYQYHLRLHSGERPYACGECGKAFRNTSCLRRHRHVHTGERPH
                     ACGVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFTC
                     PICGRGFVMAAYLQRHLRTHAPANTPPSTTAPAAGPQPPAPLAAARAPPATQDVHVLP
                     HLQATLSLEVAGGTAQAPSLGPAAPNSQTFLLVQTAQGLQLIPSSVQPPTPPPPPAPP
                     KLILLPSSSAGAGGGRARQGPRAVGKAGQGAGVVWLPGPGGLGVQGAASAGASGTGQS
                     LIVLQNVGGGEAGPQEMSGVQLQPLRPAPEVTTVQLQPAQEVTTVQLQPAQEVTTVQL
                     QPAQEVTTVQLQPVAGQLSNSSGGAVATEAPNLLVVQSGAAEELLTGPGPGEAGDGEA
                     STGVVQDVLFETLQTDEGLQSVLVLSGADGEQTRLCVQEVETLPPGLTEPPATGPPGQ
                     KLLIIRSAPATELLDSSNTGGGTATLQLLAPPPSGPASGPAGLPGAPASQMVQVVPAG
                     AGPGVMTPQGLPSIQIVQTLPAVQLVHTF"
     exon            276..3562
                     /gene="ZNF628"
                     /gene_synonym="ZEC; Zfp628"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3539..3544
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF628"
                     /gene_synonym="ZEC; Zfp628"
                     /note="hexamer: AATAAA"
     polyA_site      3562
                     /gene="ZNF628"
                     /gene_synonym="ZEC; Zfp628"
                     /note="major polyA site"
ORIGIN      
        1 gtttgtgtgc gcgagaggcc gccgataaag gttgggtgcc tcgcgccggg ggccgttggg
       61 agggagtgcg cccctgcccc ccctccccgg tccccacagc tgcaccgccg ctgccggggc
      121 cccaccttcc cgtcgacccc cgcgggaagg tcctggggct gccaccctcg ttcccccgat
      181 tggggccgca gaggcatgat caaggacagg gttgcctgcc aagaacagga ggggagagga
      241 ggggctggag gtttcaggag aaagaagcat gtcaggtgtg atggtcggct cccacgcgga
      301 catggcgccg gcctctactg cggagggggc cggggagaag ccaggccctg cggcccctgc
      361 cccggcggcc cagtacgaat gtggggagtg tggcaagtca ttccggtggt cgtcccggct
      421 cctgcaccac cagcgcacgc acacaggcga gcggccctac aagtgcccag actgccccaa
      481 ggctttcaaa ggctcctcgg ccctgctcta ccaccagcga ggccacacgg gcgagcggcc
      541 ctaccagtgc cccgactgtc ccaaggcctt caagcgctcc tctctgctgc agatccaccg
      601 tagcgtgcac accggcctgc gggccttcat ctgcggccag tgcggcctgg ccttcaagtg
      661 gtcgtcccac taccagtacc acttaaggca gcacacaggc gagcgcccct acccgtgccc
      721 ggactgcccc aaggccttca agaactcgtc cagcctgcgg cgccaccgcc acgtgcacac
      781 cggcgagcgg ccctacacct gtggagtctg cgggaagagc ttcacgcaga gcaccaacct
      841 gcggcagcac cagcgcgtgc acacgggcga gcggcccttc cgctgcccgc tctgccccaa
      901 gaccttcacc cactcctcca acctgctgct gcaccagcgc acgcacggcg ccgcccccgc
      961 cccgggtacc gcctccgcgg ccccgccccc ccagtcccgg gagcccggca aggtcttcgt
     1021 gtgcgacgcc tacctgcagc ggcacctcca gccccacagc ccgcccgcgc ctcccgcccc
     1081 gccgcccccg cccccgcccg tggtgcctga gctctttttg gcggcggcgg agaccacggt
     1141 ggagctggtg taccgctgcg atggctgcga gcagggattc agcagcgagg agctgctcct
     1201 ggagcaccag ccgtgccccg ggcccgatgc ggcgccccag ccccaggagg cacccgccga
     1261 ggcgcccaag gccgaccagc caccgtcccc tctgccgcag ccccctcctc ccgccgccgc
     1321 ccccgcgcct ggctttgcct gtctgccctg cggcaagtcc ttccggacgg tggctgggct
     1381 ctcccgccac cagcacagcc acggggctgc cggcgggcaa gcgttccgct gcggcagctg
     1441 cgacggctcc ttcccgcagc tggccagcct cctggcgcat cagcagtgcc acgtggaaga
     1501 ggccgcggcc gggcgcccgc ccccgcaggc tgaggctgcg gaggtgacct gcccccagga
     1561 accgctggcg cctgccgccc ccgtcccgcc gccacccccg tccgcccccg cttctgcgga
     1621 gcggccctac aaatgtgccg agtgcggcaa gtccttcaag ggctcctccg ggctgcgcta
     1681 ccacctgcgg gaccacacgg gcgagcggcc ctaccagtgt ggcgagtgcg gcaaggcctt
     1741 caagcgctcc tccctgctgg ccatccacca gcgggtgcac acgggcctgc gggccttcac
     1801 ctgtggccag tgcggcctca ccttcaagtg gtcgtcccac taccagtacc acctgcggct
     1861 gcactctggc gagcggccct acgcctgcgg ggagtgtggc aaggccttcc gcaacacgtc
     1921 gtgcctgcgt cgccaccgcc acgtgcacac tggcgagagg ccccacgcct gcggtgtctg
     1981 cggcaagagc ttcgcgcaga cctccaacct gcggcagcac cagcgcgtgc acacgggcga
     2041 gcggcccttc cgctgcccgc tctgccccaa gaccttcacc cactcctcca acctgctgct
     2101 gcaccagcgc acgcactcgg cggagcgccc cttcacctgc cccatctgcg gtcgcggctt
     2161 cgttatggcc gcctatctgc agcggcacct gaggacgcac gccccggcca acacgcctcc
     2221 cagcaccaca gcccctgccg ccggccccca gccccctgct ccactggctg ctgcgcgggc
     2281 cccgccagcc acccaagatg tccacgtcct gccccacctc caggccacgc tctccctcga
     2341 ggtggcgggg ggcacggccc aggccccgag cttggggcca gcagcgccca actctcagac
     2401 gttcctcctg gtgcaaactg cccagggcct ccagctgatc cccagcagcg tgcagccccc
     2461 tacacctccg ccccctcccg cacctcccaa gctcatcctg ctgccctcct ccagtgctgg
     2521 ggctgggggc ggccgtgcaa ggcagggccc gcgggcagtg gggaaagcgg gccagggggc
     2581 gggagtggtc tggctgccag gccctggggg tctaggggtg cagggagcgg ccagcgctgg
     2641 ggccagcggg acagggcaga gcctcatcgt tctgcagaat gtggggggtg gggaggcagg
     2701 gccacaggaa atgagtgggg tgcagctcca gcccctccga ccagccccag aagtaaccac
     2761 ggtccagctc cagccagcgc aggaggtgac cacagtccag ctccagccag cacaggaagt
     2821 aaccacggtc cagctccagc cagcacagga ggtgaccacg gtccagctcc agcccgtggc
     2881 cggccagctc tccaattcca gtgggggagc tgtggctact gaggcaccca acctgctggt
     2941 tgttcagagc ggggcagctg aggagttgct cactggcccg ggccccgggg aggcggggga
     3001 tggcgaggcc agcactggtg tggtccagga tgtcctcttt gagacactcc agacggacga
     3061 gggcttgcag agcgtgctgg tgctgagcgg ggccgatggc gaacagactc gactctgcgt
     3121 acaggaggta gaaacacttc ctcctgggct gacggagccg cctgccaccg gcccacccgg
     3181 acagaaactc ctcatcatcc gcagcgcccc agccactgag ctgctggaca gcagcaacac
     3241 tggaggaggc accgccacgc tgcagctcct ggccccaccg ccgtcaggcc cagcctcggg
     3301 ccccgcgggg ctccccgggg ctccagcctc ccagatggtg caagtggtcc ccgcaggagc
     3361 tgggcctggt gttatgaccc ctcagggcct gccctccatc cagattgtcc agactctacc
     3421 cgcagtccag ctggtgcaca cgttttgagg agaggcagtg attcccctcc cgccccgcac
     3481 agagaccccg actcactgcc agccggggcg gggcagggtg ccgcaggctg ggcttgctaa
     3541 taaagacccg agtctccccg cc
//
