LOCUS       NM_145233               1702 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens zinc finger protein 625 (ZNF625), transcript variant
            1, mRNA.
ACCESSION   NM_145233
VERSION     NM_145233.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1702)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 1702)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC022415.5, DB071985.1, DN991057.1 and BC007868.2.
            
            On May 17, 2019 this sequence version replaced NM_145233.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the supported protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DN991057.1, DB486997.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2155770, SAMN03267758
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000439556.3/ ENSP00000394380.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC022415.5         149579-149581       c
            4-90                DB071985.1         1-87
            91-822              DN991057.1         8-739
            823-1602            BC007868.2         799-1578
            1603-1614           AC022415.5         137825-137836       c
            1615-1702           BC007868.2         1591-1678
FEATURES             Location/Qualifiers
     source          1..1702
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.2"
     gene            1..1702
                     /gene="ZNF625"
                     /note="zinc finger protein 625"
                     /db_xref="GeneID:90589"
                     /db_xref="HGNC:HGNC:30571"
     exon            1..179
                     /gene="ZNF625"
                     /inference="alignment:Splign:2.1.0"
     CDS             177..1295
                     /gene="ZNF625"
                     /codon_start=1
                     /product="zinc finger protein 625"
                     /protein_id="NP_660276.2"
                     /db_xref="CCDS:CCDS12269.2"
                     /db_xref="GeneID:90589"
                     /db_xref="HGNC:HGNC:30571"
                     /translation="MDSVVFEDVDVNFTQEEWALLDPSQKNLYRDVMQETFRNLASVG
                     KKWKDQKIEDEYKNPRRNLRGLMGERLLESKKDHQHGEILTQVPDDMLKKKTPRVKSC
                     GEVSVGHASLNRHHRADTGHKPYEYQEYGQKPYKCTYCKKAFSDLPYFRTHEWAHTGG
                     KPYDCEECGKSFISRSSIRRHRIMHSGDGPYKCNFCGKALMCLSLYLIHKRTHTGEKP
                     YECKQCGKAFSHSGSLRIHERTHTGEKPYECSECGKAFHSSTCLHAHKITHTGEKPYE
                     CKQCGKAFVSFNSVRYHERTHTGEKPYECKQCGKAFRSASHLRTHGRTHTGEKPYECK
                     QCGKAFGCASSVKIHERTHTGEKPCSSNTSKGQGEKIA"
     exon            180..306
                     /gene="ZNF625"
                     /inference="alignment:Splign:2.1.0"
     exon            307..367
                     /gene="ZNF625"
                     /inference="alignment:Splign:2.1.0"
     exon            368..1702
                     /gene="ZNF625"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1422..1427
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF625"
                     /note="hexamer: AATAAA"
     polyA_site      1443
                     /gene="ZNF625"
                     /note="major polyA site"
ORIGIN      
        1 cccgctttcc tgactcccag gcgtcttgca ccaaagggag gtcgggatct cggttttccg
       61 gccccgagag ggaccaggtg cctccgccat agcttctgtc gctccatcgc ccgcactgtg
      121 actggactgt tagagggatc cgtggagagg aggccaggac acctggaagc cgggaaatgg
      181 attcagtggt ctttgaggat gtagatgtga acttcaccca ggaggagtgg gctttgctgg
      241 atccttccca gaagaatctc tacagagatg tgatgcagga aaccttcagg aacctggctt
      301 ctgtaggaaa aaaatggaaa gatcagaaaa ttgaagatga gtacaaaaat cccaggagaa
      361 acctaagagg tcttatggga gagagactct tagaaagtaa gaaagatcat cagcatggag
      421 aaattttgac ccaggttcca gatgacatgc tgaagaagaa aactccccga gtaaaatcat
      481 gtggagaagt cagcgtgggt catgcatccc ttaataggca ccacagagct gacactggac
      541 acaagccata tgagtatcag gaatatggac agaagccata taaatgtaca tactgtaaga
      601 aagccttcag tgatctcccc tactttcgaa cacatgaatg ggctcacact ggggggaaac
      661 cttatgattg tgaggaatgt ggaaaaagct ttatttcccg ttcaagcatt cgaagacaca
      721 ggataatgca cagtggagat ggaccctaca aatgtaactt ttgtgggaaa gccttgatgt
      781 gtctcagttt gtatcttatc cacaaacgaa ctcacactgg agagaaacca tatgaatgta
      841 aacagtgtgg taaagccttt agtcattctg gtagccttcg aatacatgaa agaactcaca
      901 ctggagagaa gccttatgaa tgcagtgagt gtgggaaagc attccatagt tccacatgcc
      961 tccatgcaca taaaataact cacactgggg agaagccgta tgaatgtaaa cagtgtggga
     1021 aagcctttgt ttctttcaat tccgttcgat atcatgaaag aactcacact ggagagaagc
     1081 cctatgaatg taagcaatgt gggaaagcct tcagatctgc ctcgcacctt cgaacacatg
     1141 gaaggactca cactggagag aaaccctatg aatgtaaaca atgtggtaaa gcctttggat
     1201 gtgcctcgag cgttaaaatc catgaaagga ctcacactgg agaaaaaccc tgtagctcca
     1261 acacttcgaa aggccaaggc gagaagattg cttaattcac ataagattcc tagaagccac
     1321 cgaatccaat catggtaaaa atgtgtttcc ctcaaatcat gggaaccatc gcaaaattat
     1381 tctgaagctt ctgcagtcac tgtcatttga cagcattcag aaataaatgc cagtagccca
     1441 ggagcaaaaa tttttgggag tagtttagct ggggcctcac tcagatacct aggacacaga
     1501 gttggaaata actcttaaga gagacacacc tccagtaaga ccttaagaca gttctgtcat
     1561 aaaaaaaata cgaggtttgg ccgggtgcag tggctcatgc ctataatccc agcactttgg
     1621 gaggccgagg caggcggacc acgaggtcag tagttcgaga ccagcctggt caatatggtg
     1681 aaaccccatc tctactaaaa aa
//
