LOCUS       NM_020787               4241 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 624 (ZNF624), mRNA.
ACCESSION   NM_020787 XR_017879
VERSION     NM_020787.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4241)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 4241)
  AUTHORS   Sahni,N., Yi,S., Taipale,M., Fuxman Bass,J.I.,
            Coulombe-Huntington,J., Yang,F., Peng,J., Weile,J., Karras,G.I.,
            Wang,Y., Kovacs,I.A., Kamburov,A., Krykbaeva,I., Lam,M.H.,
            Tucker,G., Khurana,V., Sharma,A., Liu,Y.Y., Yachie,N., Zhong,Q.,
            Shen,Y., Palagi,A., San-Miguel,A., Fan,C., Balcha,D., Dricot,A.,
            Jordan,D.M., Walsh,J.M., Shah,A.A., Yang,X., Stoyanova,A.K.,
            Leighton,A., Calderwood,M.A., Jacob,Y., Cusick,M.E.,
            Salehi-Ashtiani,K., Whitesell,L.J., Sunyaev,S., Berger,B.,
            Barabasi,A.L., Charloteaux,B., Hill,D.E., Hao,T., Roth,F.P.,
            Xia,Y., Walhout,A.J.M., Lindquist,S. and Vidal,M.
  TITLE     Widespread macromolecular interaction perturbations in human
            genetic disorders
  JOURNAL   Cell 161 (3), 647-660 (2015)
   PUBMED   25910212
REFERENCE   3  (bases 1 to 4241)
  AUTHORS   Liu,C.Y., Wu,M.C., Chen,F., Ter-Minassian,M., Asomaning,K.,
            Zhai,R., Wang,Z., Su,L., Heist,R.S., Kulke,M.H., Lin,X., Liu,G. and
            Christiani,D.C.
  TITLE     A Large-scale genetic association study of esophageal
            adenocarcinoma risk
  JOURNAL   Carcinogenesis 31 (7), 1259-1263 (2010)
   PUBMED   20453000
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA808501.1, BC103943.1 and BF435259.1.
            
            On Nov 22, 2018 this sequence version replaced NM_020787.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK131401.1, SRR1660809.166451.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000311331.12/ ENSP00000310472.7
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-493               DA808501.1         4-496
            494-3977            BC103943.1         79-3562
            3978-4241           BF435259.1         7-270               c
FEATURES             Location/Qualifiers
     source          1..4241
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17p11.2"
     gene            1..4241
                     /gene="ZNF624"
                     /note="zinc finger protein 624"
                     /db_xref="GeneID:57547"
                     /db_xref="HGNC:HGNC:29254"
     exon            1..87
                     /gene="ZNF624"
                     /inference="alignment:Splign:2.1.0"
     exon            88..176
                     /gene="ZNF624"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..2687
                     /gene="ZNF624"
                     /codon_start=1
                     /product="zinc finger protein 624"
                     /protein_id="NP_065838.2"
                     /db_xref="CCDS:CCDS11180.1"
                     /db_xref="GeneID:57547"
                     /db_xref="HGNC:HGNC:29254"
                     /translation="MSLQDSTLSREGKPEGEIMAAVFFSVGRLSPEVTQPDEDLHLQA
                     EETQLVKESVTFKDVAIDFTLEEWRLMDPTQRNLHKDVMLENYRNLVSLGLAVSKPDM
                     ISHLENGKGPWVTVREISRIPYPDMEPKPATKKATRTKAISEDLSQEAILEKLTENGL
                     WDSRMEGLWKWNDRILRLQNNQENHLSQRIIPLKKTPTSQRGFRFESILIPEPGIATE
                     ELHSRCQTQEENFTENLNLITDTHLGKIICKEMKGSKAIRQTSELTLGKKSNNKEKPY
                     KCSTCEKAFHYRSLLIQHQRTHTKEKPYECNECGKTFSQPSYLSQHKKIHTGEKPYKC
                     NECGKAFIASSSLMVHQRIHTKEKPYQCNVCGKSFSQCARLNQHQRIQTGEKPYKCSE
                     CGKAFSDKSKLARHQETHNGEKPYKCDDCGKAFRNKSYLSVHQKTHTEEKPYQCNECG
                     KSFKNTTIFNVHQRIHTGEKPFRCNECGKAYRSNSSLIVHIRTHTGEKPYECNECGKA
                     FNRIANFTEHQRIHTGEKPYKCNECGKAFINYSCLTVHHRMHTGEKPYKCTECGKAFM
                     RSSSLIIHQRIHTEEKPYLCNECGESFRIKSHLTVHQRIHTGEKPYKCTDCERAFTKM
                     VNLKEHQKIHTGVKPYKCYDCGKSFRTKSYLIVHQRTHTGEKPYKCNECEKAFTNTSQ
                     LTVHQRRHTGEKPYKCNECGKVFTSNSGFNTHQRTHTGEKPFKCNDCGKAFSQMVHVT
                     EHQKIHSGEKPYKCDVCGKAFRRGSYLTVHWRTHTGEKPYTCKECGKGCITLSQLTLH
                     QRIHTGERPYKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFRSSSSLTVHQR
                     IHQRETQLI"
     exon            177..242
                     /gene="ZNF624"
                     /inference="alignment:Splign:2.1.0"
     exon            243..369
                     /gene="ZNF624"
                     /inference="alignment:Splign:2.1.0"
     exon            370..465
                     /gene="ZNF624"
                     /inference="alignment:Splign:2.1.0"
     exon            466..4241
                     /gene="ZNF624"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4221..4226
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF624"
                     /note="hexamer: ATTAAA"
     polyA_site      4241
                     /gene="ZNF624"
                     /note="major polyA site"
ORIGIN      
        1 gccggcaccg ccgagccgcc gccattgctg gaagcgttcc cgccctgctc tgcgagttcc
       61 ctcagttgtc ctcagttcgg ccgccaggta tgtctttgca agactccact ctttccagag
      121 aggggaaacc agagggagag attatggctg ctgtgttttt ctcagttgga cgcctgagcc
      181 ctgaagttac ccagccagat gaagatcttc accttcaggc agaagaaaca caattggtaa
      241 aggaatcggt gacatttaag gatgtggcta tagacttcac attggaggag tggaggttga
      301 tggaccctac acagaggaac ctgcacaagg atgtgatgct agagaattac aggaatctgg
      361 tctccctggg gcttgcagtt tccaaaccag acatgatatc tcatttggag aatgggaaag
      421 gaccatgggt gacggtgaga gaaatttcaa gaattcccta tcctgacatg gagcccaaac
      481 ctgcaaccaa gaaggctaca cgaacaaagg ctatttctga agatttatca caggaggcca
      541 tactagagaa acttacagag aatggtctgt gggattccag aatggaaggg ttatggaaat
      601 ggaatgatag gatattgaga ttacaaaata atcaggagaa tcatttgagt caaagaataa
      661 ttccactcaa gaagactccc actagtcaaa gaggctttag atttgaatct attcttattc
      721 cagaaccagg cattgccaca gaagagcttc acagcagatg ccaaacacaa gaggaaaatt
      781 tcacagagaa tttaaatttg attacagata cccatttggg gaagataatt tgcaaggaga
      841 tgaaaggcag caaagccata aggcagactt cagaactaac tttggggaaa aaatccaata
      901 ataaggaaaa accctacaaa tgtagtacat gcgaaaaggc ctttcattat agatcattgc
      961 tcattcaaca tcaaagaact catactaaag aaaaacctta tgaatgtaat gaatgtggga
     1021 aaacattcag ccagccttca tatctcagtc agcacaaaaa aatccacact ggagaaaaac
     1081 cctataaatg taatgaatgt ggaaaggcct tcattgcttc ttcatcactt atggtacatc
     1141 agagaattca cactaaagag aaaccttatc agtgtaatgt gtgtgggaaa tcttttagcc
     1201 agtgtgcccg tcttaatcag caccagagaa ttcaaactgg agagaaaccc tataaatgta
     1261 gtgaatgcgg gaaagctttt agtgataaat caaaacttgc aagacatcag gaaactcaca
     1321 atggtgagaa accctacaaa tgtgatgatt gtgggaaagc ctttaggaac aagtcatatc
     1381 ttagtgtaca tcagaagacc cacactgaag agaaaccata tcagtgcaac gagtgtggga
     1441 agtcttttaa gaataccaca atttttaatg tgcatcagag gattcatact ggagagaaac
     1501 cttttagatg taacgaatgt ggaaaagcct atagaagtaa ttcaagcctt atcgtacata
     1561 taagaactca cactggggaa aaaccctatg aatgtaatga atgtgggaaa gcattcaacc
     1621 gcatcgcaaa tttcacagaa catcagcgaa ttcacacagg agaaaaaccc tataaatgta
     1681 atgaatgtgg gaaagcattc attaattatt catgccttac tgtacaccac agaatgcata
     1741 caggagagaa accttataaa tgtactgaat gtggaaaggc cttcatgcgt tcttcttctc
     1801 taattataca tcagcgtatt catactgaag agaaacctta tctgtgcaat gaatgtgggg
     1861 agtctttcag aataaaatca cacttaactg tacatcagag aattcacact ggagagaaac
     1921 catataaatg tactgactgc gagagggcat tcaccaaaat ggtaaatctc aaggagcatc
     1981 agaaaattca tactggagtg aaaccctata aatgttatga ctgtggaaag tcctttagga
     2041 ctaaatcata ccttattgta catcagagga cccatactgg agaaaaacca tataaatgta
     2101 atgaatgtga gaaagccttc actaatacat cacagcttac cgtgcaccaa cgaaggcata
     2161 ctggagagaa gccctataaa tgcaatgaat gtggaaaggt tttcacaagt aactcaggct
     2221 ttaatacaca tcaaagaaca catactggag agaaaccatt taaatgtaat gactgtggga
     2281 aagcatttag ccagatggta catgtcacag aacatcagaa aatccatagt ggagagaagc
     2341 cctataagtg tgatgtctgt ggaaaagcct tcaggagggg ttcttacctt acagtgcatt
     2401 ggagaacaca cactggagaa aaaccctaca cctgtaagga atgtggaaag ggttgtatta
     2461 ctctatcaca gctaacccta catcagagaa ttcatactgg ggagaggccc tataaatgtg
     2521 aagaatgtgg aaaagccttc agaactaact cagactttac tgtacacttg aggatgcata
     2581 ctggagaaaa accctataaa tgtaatgaat gtggaaaagc cttcaggagt agttcgagcc
     2641 ttactgtaca tcaaagaata catcaaagag aaactcagtt aatataaaga acaataagtc
     2701 attcacctag atgtcaactc cacaagatga atcttataaa ctatatttta tgaatatagg
     2761 aaaatcttca ttaggaattt atcagaaagt atacagagaa actataagca attatgtggg
     2821 aaatcattta ataatattaa atcttagaag ttataaggaa actctcacta gaggaaaata
     2881 atgaacaaat gaaagtgttc atccagattt catactttac tcatttaaca aattatcttt
     2941 agttaattgc ctatatatgt atttgcctat ttttctattc atttatctgt cttttcttat
     3001 aaacctggag gtgcttttta tatatttttg atattaatcc tttgtcatta tgtagcagat
     3061 gtttttctta atctagcatt tgtctttata ctttatagta atgcacaaca tttttatagg
     3121 aaaatatttg tatcatttcc tttttagatt ttttatttta ctcattttac ttaaaagaga
     3181 tctccttaat ccctaggtta tacgtagtat cctaaatgtg tttttaagat ttttatgatt
     3241 ttatttttta cacttaagtc tttaatccct ctggactgga tggttcttca taggagagca
     3301 actgtaggtg atcattatcc tgtgaaaata ttttgaacct aaaaagcact cagggaaatg
     3361 caaattgaaa tgctcagtga gatgaaactt ccccttcatg gatctggcaa aaattaagag
     3421 atcttttgct agctattggg gtttgggaaa ccatgtacta ttacttaaag gttgtgtaac
     3481 atacttccac cagcagtcca acaatatatg tttaaaaatt taaaacatat atactcttag
     3541 acccagcagt ctcacttttg gaatctgtcc gttagaaata aaagcagcat caatgcataa
     3601 gaatgtaaat aaacatgttt gttgaagtac tgtttgtaga ggggggcaaa gccccaactg
     3661 caaacaaagt gaatgcccat taatagggaa ctggttagat aaattgtgac atacccatat
     3721 tatggaacag tgtgagagta attttaaaaa cgacttatat ctatgctagc tgatttcaat
     3781 gtatttccac aatgtattga taaataattg ctttataaca aatgtatata tacaatatat
     3841 catttttgtt aaaataatca cacccattta ttttgtgttt atgtgtgtgt gtgtggttag
     3901 atgcacatgg agacaggtat ggaagaatat acaccaggct gttaatattg attaccttga
     3961 ggggagtgag aaaaggagaa gtagagataa gggaagggga gactgtaaaa acagaaaaat
     4021 gtaaatgctg cctttatggt ataaaactgt aaatgtaata ttatgtaatt atgtgaactt
     4081 ttgagagaga tgaaaggatg gtctccaaaa aattaatgat ggttatttct gttttagtgg
     4141 ttcatcaatt ttttgttttt tactttcttt tctgtgtttt taagttaatt ttttccttgc
     4201 aatgaacctg taatatttac attaaaagga aaaatatttt c
//
