LOCUS       NM_175888               3291 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens zinc finger protein 620 (ZNF620), transcript variant
            1, mRNA.
ACCESSION   NM_175888 XM_171060
VERSION     NM_175888.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3291)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   2  (bases 1 to 3291)
  AUTHORS   Qin,Y., Huttlin,E.L., Winsnes,C.F., Gosztyla,M.L., Wacheul,L.,
            Kelly,M.R., Blue,S.M., Zheng,F., Chen,M., Schaffer,L.V., Licon,K.,
            Backstrom,A., Vaites,L.P., Lee,J.J., Ouyang,W., Liu,S.N., Zhang,T.,
            Silva,E., Park,J., Pitea,A., Kreisberg,J.F., Gygi,S.P., Ma,J.,
            Harper,J.W., Yeo,G.W., Lafontaine,D.L.J., Lundberg,E. and Ideker,T.
  TITLE     A multi-scale map of cell structure fusing protein images and
            interactions
  JOURNAL   Nature 600 (7889), 536-542 (2021)
   PUBMED   34819669
REFERENCE   3  (bases 1 to 3291)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (bases 1 to 3291)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 3291)
  AUTHORS   Choy,K.W., Wang,C.C., Ogura,A., Lau,T.K., Rogers,M.S., Ikeo,K.,
            Gojobori,T., Lam,D.S. and Pang,C.P.
  TITLE     Genomic annotation of 15,809 ESTs identified from pooled early
            gestation human eyes
  JOURNAL   Physiol Genomics 25 (1), 9-15 (2006)
   PUBMED   16368877
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK131232.1, BC044953.1, BY800121.1 and AC121754.6.
            
            On May 17, 2019 this sequence version replaced NM_175888.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK131232.1, DA172830.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2142348
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000314529.10/ ENSP00000322265.6
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1621              AK131232.1         1-1621
            1622-1945           BC044953.1         1287-1610
            1946-2264           BC044953.1         1614-1932
            2265-2776           BY800121.1         91-602
            2777-3291           AC121754.6         43453-43967
FEATURES             Location/Qualifiers
     source          1..3291
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p22.1"
     gene            1..3291
                     /gene="ZNF620"
                     /note="zinc finger protein 620"
                     /db_xref="GeneID:253639"
                     /db_xref="HGNC:HGNC:28742"
     exon            1..100
                     /gene="ZNF620"
                     /inference="alignment:Splign:2.1.0"
     exon            101..173
                     /gene="ZNF620"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..1418
                     /gene="ZNF620"
                     /note="isoform a is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 620 isoform a"
                     /protein_id="NP_787084.1"
                     /db_xref="CCDS:CCDS33740.1"
                     /db_xref="GeneID:253639"
                     /db_xref="HGNC:HGNC:28742"
                     /translation="MFQTAWRQEPVTFEDVAVYFTQNEWASLDSVQRALYREVMLENY
                     ANVASLAFPFTTPVLVSQLEQGELPWGLDPWEPMGREALRGICPGDEARTEKEGLTPK
                     DHVSKETESFRLMVGGLPGNVSQHLDFGSSLEQPQGHWIIKTKSKRRHFTDTSARHHE
                     AYEVKNGEKFEKLGKNISVSTQLTTNQTNPSGQISYECGQCGRYFIQMADFHRHEKCH
                     TGEKSFECKECGKYFRYNSLLIRHQIIHTGKKPFKCKECGKGLSSDTALIQHQRIHTG
                     EKPYECKECGKAFSSSSVFLQHQRFHTGEKLYECNECWKTFSCSSSFTVHQRMHTGEK
                     PYECKECGKRLSSNTALTQHQRIHTGEKPFECKECGKAFNQKITLIQHQRVHTGEKPY
                     ECKVCGKTFSWCGRFILHQKLHTQKTPVQA"
     exon            174..300
                     /gene="ZNF620"
                     /inference="alignment:Splign:2.1.0"
     exon            301..414
                     /gene="ZNF620"
                     /inference="alignment:Splign:2.1.0"
     exon            415..3291
                     /gene="ZNF620"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2239..2244
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF620"
                     /note="hexamer: AATAAA"
     polyA_site      2271
                     /gene="ZNF620"
                     /note="major polyA site"
     regulatory      2332..2337
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF620"
                     /note="hexamer: AATAAA"
     polyA_site      2365
                     /gene="ZNF620"
     regulatory      2982..2987
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF620"
                     /note="hexamer: AATAAA"
     polyA_site      3012
                     /gene="ZNF620"
ORIGIN      
        1 aagctttccc cggtgtcggc ggcaggtgga atttccacgc tttatctgcg cctgcgccgc
       61 gcgggattcg cggtccgagc tgaagaggtt cgcggtccgg tttcacttct ccgaaccctg
      121 aggcagtgtg tgaagctggg acgccagcca tgttccagac cgcttggcgc caggaaccag
      181 tgacctttga ggatgtggct gtgtacttca cccagaatga atgggccagc ctggactctg
      241 tgcagagggc cctgtacagg gaagtgatgc tggagaatta tgcaaatgtg gcttccctgg
      301 cattcccatt caccacgcct gttctggtct cccagctgga gcaaggggaa ctgccatggg
      361 gcctcgatcc ctgggaacct atgggcaggg aggctctcag aggtatctgt ccaggggatg
      421 aggccagaac tgagaaggaa ggattaactc caaaggatca tgtgtccaaa gaaacagagt
      481 ccttcagact gatggtgggg ggcctgccag ggaatgtttc ccagcacctt gactttggga
      541 gcagcctaga gcagccacaa ggtcattgga taattaagac aaagtcaaag aggagacatt
      601 tcacagatac ctcagccagg caccatgagg cctatgaggt caagaatgga gagaagtttg
      661 agaaattagg aaaaaatatt agcgtcagca cacaactcac tacaaatcag acaaatccta
      721 gtggtcagat atcttatgaa tgtggacaat gtggcagata tttcattcaa atggcagact
      781 tccaccgaca tgagaaatgt cacactggtg aaaagtcttt tgaatgcaaa gaatgtggaa
      841 aatacttcag atataactca ttacttattc ggcatcagat aattcacact ggaaagaaac
      901 catttaaatg taaagaatgt ggaaaaggtt taagttcaga cacagccttg attcagcatc
      961 agagaatcca cactggagaa aagccctatg aatgtaagga gtgcggcaag gccttcagta
     1021 gcagctctgt cttcctccag caccagaggt tccacactgg ggagaagctc tatgaatgta
     1081 acgaatgttg gaaaactttc agttgcagct caagtttcac tgtccatcag cgaatgcaca
     1141 ctggggagaa accttatgaa tgtaaagagt gtggaaaacg attaagctcc aacacagcct
     1201 tgactcagca tcagcgaatt cacactgggg agaagccctt tgaatgtaag gagtgtggga
     1261 aggcattcaa tcagaaaata accctgattc agcaccagcg agttcacact ggcgagaaac
     1321 cttatgagtg taaagtgtgt ggtaaaacct tcagctggtg tggaagattc attctgcatc
     1381 agaaactaca cactcagaag acacctgtcc aagcataggg ctatccatag ttaggcccac
     1441 tgtgcctctc cttttttctc tttattttca tgctttttat cagtgtcctc gctgtccttc
     1501 ctggttagac acttggcttt catcatgaac tcttctttaa gttttttgaa cctgtttccc
     1561 caacatgaag tctctttatg gttagagaag accaaaaaac aaacaaacaa acttagaaac
     1621 ataaaaggaa atgtaagttt ccagatttaa aggacatgct gggtgcccag caggatggat
     1681 tcaagggaaa cctacattaa ggaaaattgc tgtgaattat gaaaacacca agtttgaata
     1741 agaggatcat ggagaaaaaa tgagacccta aaaagtttct agagagagaa aacaaaagat
     1801 cagaaatgaa agcggggcca ggcgcggtgg ctcgtgcctg taatcccagc actttgggag
     1861 gctgaggcgg gtggatcatg aggtcaggag ttcgagacca gcccgcccaa tatggtgaaa
     1921 ccccgtctct cctgaaaaaa aaaaacacaa aaattagcca ggcatggtgg cgcatgcctg
     1981 taatcccagc tactagagag gctgaggcag gagaatcact tgaatccctg aggcagaggt
     2041 tgcagtgagc tgagatcgca ccactgcact ccagcctggg cgacagagtg agactttgtc
     2101 tcaaaaacag taaaaaatga aaatggcatt agatttttca agagcaacct tcaaagtcag
     2161 atgacaatgt gtatgccttc agacttctca tggaaaatgt tttcccctgc aattctatac
     2221 tccaaagtat aagtatagaa taaaggcatt tcagaccctt taaatctgaa atctttatct
     2281 cccatgcatc ctttctcata tgtgcaacac tacacaagga gtaaaccagt aaataaaaag
     2341 acagatatat ggattcccta ttgcagtccg tacgtcagaa gtctcctaaa ttcaaaaacg
     2401 ggccctgtcc atgtggagcc aaatgcatct tggaagacat tcctagtagg gtgcaaactt
     2461 ccagagacct atctcaggtt cagtgtccac ccaccctact tattcttcag tttgtcttca
     2521 ctagacagtt gtactctgtg cctttgcaaa agtcaggatg tatatactct ttgagtcagg
     2581 tgcaaggcac catttgtctt aaatttattc tcattgctgt ttcaagtgac ctcaaagcag
     2641 gcagcatttt cttgcaattc catctagtta ttttttatga tcatggaaga acctaccatt
     2701 attgctgtta cctgtggaaa tgagggaaga tgtaaatgtg ttaggtttta gcatcccctc
     2761 tggcagccag cttgattttg caggaagcag agagtagtga ttaataatac agagccaggc
     2821 agactttggt ttgagtccag gtgtttgtcc ttggttaagt tacaaaaact gcactagttt
     2881 ccttatctgt aaaatgagga tgacagttaa tctacctcat aggtttgtgt tggggattaa
     2941 atgcattatt tgtagaagtg tttcaaacag tgactacata taataaaagt attacctatt
     3001 attggccggg cacagtggct catgcctgta atcccagcac tttgggaggc tgaggtgggc
     3061 agatcacaag gtcaggagat caagaccatc ctgctaacac actgaaaccc tgtctctact
     3121 aaaagtacaa aaaattagct gggcgtgggg tgacatgtgc ctgtagtccc agctacttgg
     3181 gaggctgagg caggagccca gggaggcaga ggttgcagtg agccaagatc atgccactgc
     3241 actccagtct gggtgacaga ttgagactcc gtctcaaaaa aaaaaaaaaa a
//
