LOCUS       NM_001318042            9363 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens zinc finger protein 618 (ZNF618), transcript variant
            4, mRNA.
ACCESSION   NM_001318042 XM_005251694
VERSION     NM_001318042.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9363)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 9363)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 9363)
  AUTHORS   Liu,Y., Zhang,B., Kuang,H., Korakavi,G., Lu,L.Y. and Yu,X.
  TITLE     Zinc Finger Protein 618 Regulates the Function of UHRF2
            (Ubiquitin-like with PHD and Ring Finger Domains 2) as a Specific
            5-Hydroxymethylcytosine Reader
  JOURNAL   J Biol Chem 291 (26), 13679-13688 (2016)
   PUBMED   27129234
  REMARK    GeneRIF: study suggests that ZNF618 is a key protein that regulates
            UHRF2 function as a specific 5hmC reader in vivo.
REFERENCE   4  (bases 1 to 9363)
  AUTHORS   Letra,A., Menezes,R., Govil,M., Fonseca,R.F., McHenry,T.,
            Granjeiro,J.M., Castilla,E.E., Orioli,I.M., Marazita,M.L. and
            Vieira,A.R.
  TITLE     Follow-up association studies of chromosome region 9q and
            nonsyndromic cleft lip/palate
  JOURNAL   Am J Med Genet A 152A (7), 1701-1710 (2010)
   PUBMED   20583170
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   5  (bases 1 to 9363)
  AUTHORS   Yoshida,T., Kato,K., Yokoi,K., Oguri,M., Watanabe,S., Metoki,N.,
            Yoshida,H., Satoh,K., Aoyagi,Y., Nozawa,Y. and Yamada,Y.
  TITLE     Association of genetic variants with hemorrhagic stroke in Japanese
            individuals
  JOURNAL   Int J Mol Med 25 (4), 649-656 (2010)
   PUBMED   20198315
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   6  (bases 1 to 9363)
  AUTHORS   Oguri,M., Kato,K., Yokoi,K., Yoshida,T., Watanabe,S., Metoki,N.,
            Yoshida,H., Satoh,K., Aoyagi,Y., Nozawa,Y. and Yamada,Y.
  TITLE     Assessment of a polymorphism of SDK1 with hypertension in Japanese
            Individuals
  JOURNAL   Am J Hypertens 23 (1), 70-77 (2010)
   PUBMED   19851296
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 9363)
  AUTHORS   Yoshida,T., Kato,K., Yokoi,K., Oguri,M., Watanabe,S., Metoki,N.,
            Yoshida,H., Satoh,K., Aoyagi,Y., Nozawa,Y. and Yamada,Y.
  TITLE     Association of gene polymorphisms with chronic kidney disease in
            Japanese individuals
  JOURNAL   Int J Mol Med 24 (4), 539-547 (2009)
   PUBMED   19724895
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC036039.1, AL137850.12 and AJ420454.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001318042.1.
            
            Transcript Variant: This variant (4) has multiple differences in
            the coding region but maintains the reading frame, compared to
            variant 1. This variant encodes isoform 4, which is longer than
            isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC036039.1, SRR14038191.4307906.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1970526, SAMEA2144120
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000374126.10/ ENSP00000363241.5
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-792               BC036039.1         31-822
            793-793             AL137850.12        4671-4671
            794-1064            BC036039.1         824-1094
            1065-1065           AL137850.12        25031-25031
            1066-1142           BC036039.1         1096-1172
            1143-1143           AL137850.12        25109-25109
            1144-2055           BC036039.1         1174-2085
            2056-2056           AL137850.12        45436-45436
            2057-2962           BC036039.1         2087-2992
            2963-8160           AL137850.12        46343-51540
            8161-9363           AJ420454.1         10-1212
FEATURES             Location/Qualifiers
     source          1..9363
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q32"
     gene            1..9363
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /note="zinc finger protein 618"
                     /db_xref="GeneID:114991"
                     /db_xref="HGNC:HGNC:29416"
                     /db_xref="MIM:617077"
     exon            1..105
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..2937
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /note="isoform 4 is encoded by transcript variant 4;
                     neural precursor cell expressed, developmentally
                     down-regulated 10"
                     /codon_start=1
                     /product="zinc finger protein 618 isoform 4"
                     /protein_id="NP_001304971.1"
                     /db_xref="CCDS:CCDS83402.1"
                     /db_xref="GeneID:114991"
                     /db_xref="HGNC:HGNC:29416"
                     /db_xref="MIM:617077"
                     /translation="MNQPGGAAAPQADGASAAGRKSTASRERLKRSQKSTKVEGPEPV
                     PAEASLSAEQGTMTEVKVKTELPDDYIQEVIWQGEAKEEKKAVSKDGTSDVPAEICVV
                     IGGVRNQQTLDGKAPEGSPHGGSVRSRYSGTWIFDQALRYASGSYECGICGKKYKYYN
                     CFQTHVRAHRDTEATSGEGASQSNNFRYTCDICGKKYKYYSCFQEHRDLHAVDVFSVE
                     GAPENRADPFDQGVVATDEVKEEPPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVA
                     LHAPISTAPGWEPPDDPDTGSECSHPEVSPSPRFVAAKTQTNQSGKKAPASVVRCATL
                     LHRTPPATQTQTFRTPNSGSPASKATAAESAFSRRVEGKAQNHFEETNSSSQNSSEPY
                     TCGACGIQFQFYNNLLEHMQSHAADNENNIASNQSRSPPAVVEEKWKPQAQRNSANNT
                     TTSGLTPNSMIPEKERQNIAERLLRVMCADLGALSVVSGKEFLKLAQTLVDSGARYGA
                     FSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQSVGPDSCYIL
                     TAYQAEGNHIKSYVLGVKGADIRDSGDLVHHWVQNVLSEFVMSEIRTVYVTDCRVSTS
                     AFSKAGMCLRCSACALNSVVQSVLSKRTLQARSMHEVIELLNVCEDLAGSTGLAKETF
                     GSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQSLNKHLLSNLAAILT
                     PVKQAVIELSNESQPTLQLVLPTYVRLEKLFTAKANDAGTVSKLCHLFLEALKENFKV
                     HPAHKVAMILDPQQKLRPVPPYQHEEIIGKVCELINEVKESWAEEADFEPAAKKPRSA
                     AVENPAAQEDDRLGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVP
                     AVGARSGCVNMCEQALLIKRRRLLSPEDMNKLMFLKSNML"
     exon            106..149
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            150..409
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            410..505
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            506..583
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            584..622
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            623..712
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            713..748
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            749..826
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            827..916
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1156
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1240
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1318
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..1420
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..9363
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9344..9349
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /note="hexamer: AATAAA"
     polyA_site      9363
                     /gene="ZNF618"
                     /gene_synonym="FP13169; NEDD10"
                     /note="major polyA site"
ORIGIN      
        1 attgtgcgcg caccagcagc ccggcccggg aggagcagga cgcgccgggg ccgcctcctc
       61 ccgcacggac ccatgaacca gccgggcggc gcggcggctc cgcaggctga cggagccagt
      121 gcagccggaa ggaaaagcac tgcgagcagg gagcgcttga agcgcagcca gaagagcacc
      181 aaggtggagg gcccagagcc agtgccagcc gaggcctcgc tgagtgccga gcaaggaacg
      241 atgacggagg tgaaggtgaa gacagagctg cccgatgact acatccagga ggtgatctgg
      301 cagggcgagg ccaaggagga gaagaaggcg gtcagcaagg atgggaccag cgacgtgcct
      361 gccgagatct gcgtggtgat cggcggcgtc cgcaaccagc agacccttga tggaaaagcg
      421 cccgaaggca gcccccacgg tggatctgtg cgaagccggt attcagggac ctggattttt
      481 gaccaagcat tgagatatgc atctgggtct tacgaatgcg gaatctgtgg caagaagtac
      541 aagtattaca actgcttcca gacccacgtg cgggcgcacc gagacaccga agccacctca
      601 ggggagggag cctcccaaag caacaatttc aggtacacat gtgatatctg cgggaagaag
      661 tacaaatact acagctgttt ccaagagcac cgagacctgc acgcagtgga tgtgtttagt
      721 gtggaagggg cccctgagaa ccgggcagac cccttcgacc aaggtgtcgt ggccacggac
      781 gaggtgaagg aggagccccc ggagccattc cagaaaatcg ggccaaaaac tggcaattac
      841 acctgtgaat tctgcggcaa acagtacaag tactacactc cctaccagga gcatgtggcc
      901 ttacacgccc ccatcagtac tgcccccggg tgggagccac cggatgatcc agacacgggc
      961 tctgagtgtt cacatccaga ggtctcccca tctccacgct tcgtggcagc gaagacccag
     1021 acgaaccagt cggggaaaaa agctccggcc tccgtggtcc gatgtgccac cctcttacac
     1081 cgcacccctc cagccaccca aacccagacg ttccgcactc caaattcggg atctccggcg
     1141 agcaaggcaa ccgcagcaga aagcgctttc agtcggagag tagaaggcaa agcacaaaac
     1201 cactttgaag agacgaacag cagttcgcag aactccagcg aaccctacac ctgcggcgcc
     1261 tgtgggatcc agttccagtt ctacaacaac ctgttggagc acatgcagtc ccatgcagct
     1321 gacaatgaaa acaacattgc ctccaaccag tcccgatcgc cacctgctgt tgtagaagag
     1381 aagtggaaac ctcaggccca gaggaacagt gccaataaca ccactaccag tggtttaaca
     1441 cccaacagca tgatccccga aaaggagcgg cagaacatcg cagagcggct gttgagggtc
     1501 atgtgtgccg acctgggtgc actgagcgtg gtcagcggga aggagttcct gaagttggcc
     1561 cagaccttag tagacagtgg tgcccgctat ggggccttct cggtcactga aatcctgggc
     1621 aacttcaaca cgctggcgct gaagcacctg ccacgcatgt acaaccaggt gaaggtgaaa
     1681 gtgacctgtg ccttgggcag caatgcctgc ctaggcatcg gtgtcacctg ccactcccag
     1741 agtgttggcc ctgactcctg ctacatcctc acagcctacc aggccgaggg caaccacatc
     1801 aagagctatg tgcttggtgt gaagggtgcg gacattcgcg acagcggtga ccttgtgcac
     1861 cactgggtgc agaacgtgct gtcggagttc gtgatgtcgg agatcaggac agtgtacgtg
     1921 acggattgcc gggtgagcac gtccgccttc tccaaggccg gcatgtgcct tcgctgctca
     1981 gcctgtgcct tgaactcggt ggtgcagagc gtgctgagca agcggacact gcaggcccgc
     2041 agcatgcacg aggtcatcga gctgctcaac gtgtgcgagg acctggcggg ctccacgggc
     2101 ctggccaagg agaccttcgg gtcgctggag gagacgtctc caccaccctg ctggaactcg
     2161 gtgacggact cactgttgct ggtgcatgag cgctatgagc agatctgcga gttctacagc
     2221 cgggccaaga agatgaacct catccagagc ctcaacaagc acctgctcag caacctggcg
     2281 gccatcctga cgccggtgaa gcaggcagtc atcgagctga gcaacgagag ccagcccacc
     2341 ctgcagctgg tgctgcccac ctacgtcagg ctggagaagc tgttcacggc caaggccaac
     2401 gacgcaggca ctgtcagcaa gctctgccac ctcttcctgg aggcgctcaa ggagaacttc
     2461 aaggtgcacc cggcccacaa ggtggccatg atcctggacc cgcagcagaa gctgcggcct
     2521 gtgccaccct accagcacga ggagatcatc ggcaaggtct gtgagctcat caacgaggtg
     2581 aaggagtcct gggccgagga ggccgacttc gagcccgctg ccaagaagcc ccgctctgct
     2641 gccgtcgaga accccgcagc tcaggaagat gatcggctag gcaaaaatga agtgtacgat
     2701 tacctgcagg agcccctctt ccaggctacc cctgatctct tccagtactg gtcgtgcgtt
     2761 acccaaaagc acacaaaact cgccaagctc gccttctggc tcctggcggt tccggccgtg
     2821 ggcgccagaa gcgggtgtgt aaatatgtgt gaacaagcgc ttctaatcaa acggaggcgg
     2881 ctgctcagtc cagaagatat gaataaactc atgtttctga aatccaacat gctttaagac
     2941 ttgacttcgg gggaaaaaaa aagaaaaaga gaagataaca ttagaaaaaa accacacaac
     3001 actgtcacaa agaaaaggaa tttaagttct aaacactgtg gacctcatta taaatgcccc
     3061 ctggaaactt aagtgctttt tttatatgtg tgtgtgtgcg tgtatgtaca cagccacacg
     3121 tgtgtgcacg tgtctgaaca cgtgctgtgg ttgtgggggt gtgggggggt ctctgtgctc
     3181 atctccatgg ccagagaaac tttgcacaca cgcacacaca cacacacaca cacacacaca
     3241 cacacgaccc tggtgcgtgt acatacgcct gtgcttggac gggtgtgcat tgaactgggc
     3301 gtgtcaggaa agctgagcga ttgggaaaga gggagatgtt tcacctcctt ttctcagtaa
     3361 gggggcttta gaagactccg ctttcaggtg tgcagattgg cagaaagctg atgttgtgaa
     3421 atgttcaggc agctgagatc tgaagtgact tgacgctctc tgtccttcac cccggtcctc
     3481 cttttccctc tttgaccctc ttccagccct cctaccctcc tgatcccatt gtgcaccccc
     3541 ccacacactc ggctgctctg ctgtggactc tccacactgc atcagatgga cggtttctgc
     3601 actggacttt gtttcttgtt caccttcagg gcattgagct gctgcctttg agatacccct
     3661 tgggtgtccc ggggcagccg ccttagaaac acacctatct atctccccaa atcaggaaag
     3721 gagacttaaa gagtataaag ctgacatttt gctttttaat ataagagagg agaaaaagac
     3781 atttttcaga gaagtataga tactgtctcc actccctaat aatttctctc cctaacattt
     3841 tagcaatttt taccttgttt gggggttcat tttgtttctt cagatttgat ttagactctg
     3901 ctaggaggca ctgaatgtct ataacttatg ttttggagtt ttgttttttt acttgcccct
     3961 tttgttcctc aagtcacact gtaaactagc tcatctctgt ggtgtactca gtatcctaca
     4021 gtctttcttg gccttccctg tacagttcag ttttcacata ttcgaacggc caagaccagg
     4081 ttcttggctg tgctatttgg agaccaggcg ttggggagga ttcacgggtt ccacagctgc
     4141 ggggtttggt ggccgtaggg gaagcagtgg tttgggagtt ctgaatgtaa gcgccagagc
     4201 tgccctcctg gtccgctgtg cgtggtaccc agtgtgcatc acactactca ccccctcccg
     4261 gaccctggca gtccacagcg actccgaagt cagcccatag tcacatccac cacacctcag
     4321 acctgccaca gcctctcctc acttcccagg accctgaggc ttccaggagc tctgctgccc
     4381 acagccctcg gggtcctcac tcacacctcc gacttccagg acggcagtga gcatggtgcc
     4441 ttgtggcccc aacagttgat gttccgaggg tgggatggtg tttggccatg ttcgactcga
     4501 tgctgtgaaa gatgtcttca ggcttttctc tcctgttccc ccagctgtga gcaaattagg
     4561 ttctacacac acagttcgga tgccaagggt gacaccccat tcccttcaca agaggcggtt
     4621 ctgtcacaaa tcagcactcc acccccacca cacctctcag tgaatgaagt gctggtggtc
     4681 tcactcccct ggtgaccctt agccgtggga tggggtggtt acactaaggc ttcaagctga
     4741 gaatggccat catggcggga ggctgtttgc aaaggcacct tctgtcatcc tggggttggc
     4801 taagtcaact ccaccccttc ccaataataa agcatcactc aactgtgaga tacctcgact
     4861 acaaaaagca ctgtaccaca gccctctccc cctgggtcca tgacaggagc agggagtaaa
     4921 gttgattgca aacctcatga aggcttagga tcatggacct ggaacatagt gtttgggggc
     4981 caagcctgca cactttgcct catgagaact cacccagctc tccccttgaa acttggacac
     5041 actgaaatgg atcaaagtgg gccatttcca catttgctcc agcaaactgt ggtctcagga
     5101 actaccatgc catttcctct cctggagaag ttctaggtat tacctccaca acatttccaa
     5161 ctgggggact gagcccactt atcagagaag agccgccatc cacactggag caggaacagg
     5221 gagaaatcca gacaggaacc tcatgtcact tcctagggaa tatgggaaga aacatcagca
     5281 gactttatga tgtcagttgg gcctttggag gcattctgga aggtggcctc agcatcactg
     5341 atgattgaca gatgctacag caaaaggtcc ctctagcgtt gcttgactgc tggggaaggg
     5401 acagtgaccg gcactttgac ccacacaagg ataggagctg cctactttgt gtggtaggtg
     5461 agagcagagc ctgggagccc atcctccctc tacttggagc aaagttgtgc tggtgatgcc
     5521 ccattattgg gccagttgat tagaaaatag gcatttcact ttcttggaaa gccatcggac
     5581 taagcccaga tgtgcattta gagcactcag cattcttctc tttgaagcat gggatgtctg
     5641 tcctccagga agagatttga tcttaggttg ttacctccct ttcacttctt ttccacctca
     5701 attcaatact taggggttgg cttgcctctg caggtttgat gtgaatgcca ctgggtactc
     5761 agaaagctgt cctctggggc tgccttgtcc agttagataa caagatagca gatgattgtt
     5821 tcttgcaacc tctggttccc tccggaaact ggtgtcacca acaggaaagg ctgtaccaag
     5881 gtgccctctt ctcagacagg ctgttctcag agtgcaaatc ctgctgcaac taacagctta
     5941 ataaaaccca aagatctcac aggtccagcc actggcccct ttatctccaa caatatccac
     6001 ctcaccaaat tctagttcag ccaaaggatt gagacaggct cttccagttc atctcctggt
     6061 gtccagcctg accttcacat ctggaaggat tttgtcgtct gcctcccagt tctgggtcca
     6121 ctgtaggtct ttccatcaca agcctttggg ggatctggga ccaggaattt gggccgtttc
     6181 taccatattc tcagcagcct aaggtggtgg cctgctgatg tggagactac tcaccttgag
     6241 ccatgtggtc cccaggacag aaatggcctt tgttttgaca tacatggacc caaaagggga
     6301 ggtgaagaaa acacacctcc acctggcaag tttttctccc tcatctgagg tcagttgctt
     6361 caccaacaaa gcccaagcca agaactgcag cgttgagggt tgtccctcgg agtggagtag
     6421 cccaaggaat ctcaggtcca ccaagagcat tggtaccatc tgggccacgg gtggatgcct
     6481 ttgttctggc acagttctcc acttcccgat tcctggctca gccagccagg cctccctcta
     6541 atggcattta gtaaccagga aacaaaacac atgccacctg agcaaaactg cctgcacttc
     6601 atctctggag gttcgctgca cagaggccac ctgccgcatc accagtgagg aagctttgcc
     6661 accatcctgc ttggcagctt cacacttgac atctgaggat tggtttttgg ctggaaaaag
     6721 ggtaccaggg tttcctggca aggacaggag agcagtgcag tgacacagat gagaagctgt
     6781 gagtctccag gattcaagga agccaccagg tgtgcaggct gggaagagac atctctttca
     6841 gtttgaccct ttatctcctg cacttttaaa gaaacaccag agaaaaaatc tacaaggcgt
     6901 gtttccactg aagctgaacc tctgccttta ggagtcccct atatttgagc aaggccacct
     6961 gcttcccctg gacttgagct ggactccttg aagagtgggc ttctggagag atgttaggaa
     7021 tatagcacat gctctctggg ggccacaggg tcattgggaa ggtttgaaat gaagatggga
     7081 tgtggctgga acagcctgtg agatggctcc attggggaca ctcccctcat cttgtcatca
     7141 cgatggatat gctggaagag gaggtgtccc agtgagccgc ccgaagttca tagctttgcc
     7201 ctcgccttgg caacagcggc aatgcctcta tctctgggat gcatcttaag gagggctcct
     7261 aacaaggccg atgatttaga cagaacaaga gactaagtaa ggtccggcta tcccgtggag
     7321 ccagtagtag gtgggagctc ctgtccccgc cagccctgct ccagcccccg tgtccagctg
     7381 ggccagtgga agaactggga aggaggaagc ccctcccttt cactgtggct aatgtttgct
     7441 aggccagtta tggtgaacca atgatacagt gttttccctc ttaacgttcc cctcctggtt
     7501 ttgccttttc agggttttct gggggatttt gttgtagtag ttgcttttct tcctctctca
     7561 tttgggtttg aggattgtgg tcgggggagc cctggctttc accaaaggag cccagtggtt
     7621 tctgtggaag aggcgcccac tcccacttta atgagggtga agattgtcag gtcactgttt
     7681 gacatattca tgccccgtcc cttccccccc cacccccccg cccacccacc acgggtgtcg
     7741 ctttaaagag tcaattcttg tacagagaag gatttgctag gtttgcattt gggtgttagc
     7801 atcacgaccc acgagggccc tgcccaaccg tgcgtcccat ggggcacctt gactcttcaa
     7861 accaaaattc cttaaagggg cacagcccag ccttgtccgc aacctcaggg gcctgggatt
     7921 cctgtggcgc ttcctgaatt ccaggttggc acagatgatg aggtctgaga ccagccggaa
     7981 ggaggggctc ctgccataac ccaggtgcca gccggtctcc gcctaggacc ttccctcccg
     8041 cccagccagg gtgggcggca tcctacgcgg tgaaacgagc tcatggactg acccggggct
     8101 gggcctcgcc agccaggaga gagcgagggc cgcacggcag ggctggccca ggcagctcgt
     8161 ccagggccat tcagatccca agcatcagga aatcattttg tacaaccacc cgaagcagag
     8221 atatttttta agaagcgtaa attattttca gttgttttct gatcctgcct ttttcttttc
     8281 cccacaactt cacgccagtg agtcgttcac atcaggtaaa tcttgagaaa gccttggtgc
     8341 cctcctcccc accccccact cagtaaccac gtgcgtgcac ccccgcatcc tttctcagta
     8401 gttaagacgt tctaggcaat accatagaca catctgactg tgtctctctc tttgagtgca
     8461 agaaactcaa gtcatcttaa aaaaaaaaaa atacaaaaaa aatttacaaa aaaacaaaca
     8521 caaaaaaaat atctttttta ggccagagtt ttctacaggt attaatgaat atttttctta
     8581 atccttataa gttttatgtg tttaatattt cttaataccg gtagcattaa tttatacttt
     8641 tgtagcaaca caatattttt ataaacagcc ggtgcttggc tcaagtcttc acgaggggtt
     8701 taggcagggc catcttgggg accctgtgta ccatgtactg tatttaaaaa aaaaaaaagt
     8761 tacctattgt cacacttgct gtgttaatta acaaaagatg ttgtgtgcgg tctcctgtat
     8821 cggtgtggat ccaacagctc tccagggagt cacattgcat gggggttgag ttgacggttc
     8881 ttgtgatatg taaacccccg agaccaaact tgagggttta tttagggttt tctgtttgtc
     8941 ctttgggttt ttgtttcact ttgttttggt gccgtttctc catttacagc caaatcagtt
     9001 tcatgatgtt caaaacattt actgatgtca aatggaggaa aggaacagaa aaaaagattt
     9061 ttacaaagta ataaaattta aaactgagct gtttaatgtt gctgttttta cctgtctgtt
     9121 cttgtccaaa agtggaacat tcccagggag aagaggaagg ttccactcgg ttctttaagt
     9181 cgccaaaagc cccagcccgg gattcagtac ctcccctgcc ccccgaattc ttgcagcact
     9241 atttcccagt tggttgatgc caaggcaaaa agataacttt taacagttag agaggatcag
     9301 ttgcttaaat gatttcatgt cagtgttgta tttatggttt tacaataaaa caacctttag
     9361 gaa
//
