LOCUS       NM_025040               4628 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 614 (ZNF614), mRNA.
ACCESSION   NM_025040 NM_138351
VERSION     NM_025040.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4628)
  AUTHORS   Wu,A.C., Himes,B.E., Lasky-Su,J., Litonjua,A., Peters,S.P.,
            Lima,J., Kubo,M., Tamari,M., Nakamura,Y., Qiu,W., Weiss,S.T. and
            Tantisira,K.
  TITLE     Inhaled corticosteroid treatment modulates ZNF432 gene variant's
            effect on bronchodilator response in asthmatics
  JOURNAL   J Allergy Clin Immunol 133 (3), 723-8 (2014)
   PUBMED   24280104
REFERENCE   2  (bases 1 to 4628)
  AUTHORS   Simonis,N., Rual,J.F., Lemmens,I., Boxus,M., Hirozane-Kishikawa,T.,
            Gatot,J.S., Dricot,A., Hao,T., Vertommen,D., Legros,S., Daakour,S.,
            Klitgord,N., Martin,M., Willaert,J.F., Dequiedt,F., Navratil,V.,
            Cusick,M.E., Burny,A., Van Lint,C., Hill,D.E., Tavernier,J.,
            Kettmann,R., Vidal,M. and Twizere,J.C.
  TITLE     Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses
  JOURNAL   Retrovirology 9, 26 (2012)
   PUBMED   22458338
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DC368937.1, DA940231.1, BC101394.1 and AC011468.8.
            
            On Nov 22, 2018 this sequence version replaced NM_025040.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.79063.1,
                                           SRR1660807.194771.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2467148 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000270649.11/ ENSP00000270649.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                DC368937.1         49-104
            57-114              DA940231.1         89-146
            115-2896            BC101394.1         1-2782
            2897-4628           AC011468.8         29013-30744         c
FEATURES             Location/Qualifiers
     source          1..4628
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.41"
     gene            1..4628
                     /gene="ZNF614"
                     /note="zinc finger protein 614"
                     /db_xref="GeneID:80110"
                     /db_xref="HGNC:HGNC:24722"
     exon            1..138
                     /gene="ZNF614"
                     /inference="alignment:Splign:2.1.0"
     exon            139..369
                     /gene="ZNF614"
                     /inference="alignment:Splign:2.1.0"
     CDS             355..2112
                     /gene="ZNF614"
                     /codon_start=1
                     /product="zinc finger protein 614"
                     /protein_id="NP_079316.2"
                     /db_xref="CCDS:CCDS12847.1"
                     /db_xref="GeneID:80110"
                     /db_xref="HGNC:HGNC:24722"
                     /translation="MIKTQESLTLEDVAVEFSWEEWQLLDTAQKNLYRDVMVENYNHL
                     VSLGYQTSKPDVLSKLAHGQEPWTTDAKIQNKNCPGIGKVDSHLQEHSPNQRLLKSVQ
                     QCNGQNTLRNIVHLSKTHFPIVQNHDTFDLYRKNLKSSLSLINQKRRHGINNPVEFIG
                     GEKTLLHGKHERTHTKTRFSENAKCIHTKFQVFKHQRTQKIEKPHACIECEQTFLRKS
                     QLIYHENICIQENPGSGQCEKLSRSVLFTKHLKTNTTDKICIPNEYRKGSTVKSSLIT
                     HQQTHTEEKSYMCSECGKGFTMKRYLIAHQRTHSGEKPYVCKECGKGFTVKSNLIVHQ
                     RTHTGEKPYICSECGKGFTMKRYLVVHQRTHTGEKPYMCSECGKGFTVKSNLIVHQRS
                     HTGEKSYICSECGKGFTVKRTLVIHQRTHTGEKSYICNECGKGFTTKRTLIIHQRTHT
                     GEKPYECNECGKAFSQKICLIQHERCHTGKTPFVCTECGKSYSHKYGLITHQRIHTGE
                     KPYECNECGKAFTTKSVLNVHQRTHTGERPYGCSDCEKAFSHLSNLVKHKKMHTREMG
                     RISQVENSCNGESQLLPYK"
     exon            370..496
                     /gene="ZNF614"
                     /inference="alignment:Splign:2.1.0"
     exon            497..592
                     /gene="ZNF614"
                     /inference="alignment:Splign:2.1.0"
     exon            593..4628
                     /gene="ZNF614"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4607..4612
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF614"
                     /note="hexamer: AATAAA"
     polyA_site      4628
                     /gene="ZNF614"
                     /note="major polyA site"
ORIGIN      
        1 ggtcctcgcc tcgcttcacg gtctttaccg ctcagcttcc cggagtccgc gcaggagcgc
       61 gtctgaatag gaagcgtttt cggacgtgga tgcggcgttt tgtcgctgcc agtggtgtct
      121 ggagaggttc gggctcggtc ctcaggtcct ggctcccaga agcaaaataa ctcaagtgaa
      181 gcaatgaagg aagaagaagg aggttgctgg ccttggatat cataatttct ggggacaact
      241 ttaagtggac actaatattt ctgactagga aaacttcaaa aacttcatgg caaatgcaga
      301 agagacaaag acgtatagtc catgttatcc actattttct gagcacagaa gaaaatgatc
      361 aagacccagg aatcactgac cctggaggat gtggctgtgg aattcagctg ggaggagtgg
      421 cagctcctgg acactgctca gaagaacctg taccgggatg tgatggtgga gaactataac
      481 cacctagtat cactggggta tcaaactagc aaaccagatg tactctccaa gttggcacat
      541 ggacaagaac catggacaac agatgctaaa attcagaata aaaattgtcc aggaatcggg
      601 aaagttgaca gtcatctgca agagcactct ccaaaccaaa gacttctgaa gagcgtgcag
      661 caatgcaatg gacagaatac acttagaaat attgtacatc tcagcaagac acattttcct
      721 atagtgcaaa atcatgatac atttgacttg tacagaaaaa atttgaaatc aagtttaagt
      781 ttaatcaacc agaagagaag acatggaata aataaccctg ttgagtttat tggaggtgag
      841 aaaacacttc tacatggtaa gcatgaacgt acgcatacta aaactagatt ttctgaaaat
      901 gcaaaatgta tccatactaa attccaagtc ttcaagcatc agaggactca gaaaattgag
      961 aaaccccatg catgcattga atgtgagcaa accttcctta ggaagtctca gctcatttac
     1021 catgagaaca tttgtataca agagaatcct ggaagtggtc aatgtgagaa attatccaga
     1081 agtgtcctgt tcactaagca tctgaaaact aatacaacag acaaaatctg tatacccaat
     1141 gaatatagaa aaggctctac tgtgaagagt agtctcatta cacatcaaca aacccataca
     1201 gaagagaaat cctatatgtg cagtgagtgt ggaaagggct ttacaatgaa gcgctatcta
     1261 attgctcatc agcgaactca tagtggagag aaaccttatg tgtgcaaaga atgtggaaaa
     1321 ggtttcactg tgaagagcaa tctcattgta catcagcgaa ctcatacagg ggagaaaccc
     1381 tatatatgca gtgaatgtgg aaaaggcttc accatgaagc gctatcttgt tgtacatcag
     1441 cgaactcata ctggagagaa accctatatg tgcagtgaat gtggaaaagg ctttaccgtg
     1501 aagagcaatc tcattgtaca tcagcgctcc cacacaggag aaaaatctta catatgcagc
     1561 gaatgtggaa aaggcttcac tgtcaaacgc actctcgtta tacatcagcg aactcataca
     1621 ggagagaaat cttacatatg caatgaatgt ggtaaaggct tcaccacaaa gcgcactctt
     1681 attatacatc agcgaactca tacaggagaa aaaccctatg aatgcaatga atgtggtaaa
     1741 gccttcagcc agaaaatatg cctcatacaa catgagagat gtcatacagg aaagactccc
     1801 tttgtatgta ccgagtgcgg aaaatcctat tcacacaaat atggcctcat tacccatcag
     1861 agaattcaca caggagagaa accttatgag tgcaatgaat gtggaaaagc cttcaccaca
     1921 aagtcagtac tcaatgtaca tcaaagaacg catacaggag agaggccgta tggatgcagt
     1981 gattgtgaga aagccttctc ccacttatca aaccttgtca aacataagaa aatgcacaca
     2041 agagaaatgg gtagaatcag tcaagttgaa aactcctgta atggagagtc acagctcctt
     2101 ccttataagt gaactcatgc agaagaaaac cctactagtg ccgtgactat ggaaatgcct
     2161 tttgtggcaa ctcagacttc attaaacatc agtgtgtttc tagccaattg gaacataaac
     2221 atggtgctgc ctgttgacag atgtgtgtct gtcctcagga ggtgaaataa tttgccctag
     2281 agatcaattt gatgaataca gtaaataagg tagtgccttt agtggtcttt tacctcatat
     2341 tttctgtcaa tgaaaatacg ttgaataaac tatattaatg tggagatgtt ttgagcaata
     2401 atttctgctc atatgtctga aaagtataca gagataaatt ctgtgaatac aaagactaag
     2461 aaaagtcttc tgtggaaaga tagactttat tatcaggttt catcatagat ttcaacgtaa
     2521 gtgagcttat tgttgataga aacatgatga ccatgacaaa gtctttactc agaaatatga
     2581 cctcagtgag tgtcaaagtt tacactggaa aataacttta aggtgacagt attgatggca
     2641 ggatttcagc gacgcactct gcttcatcat ttgtcaggag atcacataga aagtaaaatt
     2701 gttccgaaca tgctatcaaa taaatgtgga acacctttag caaactatca acagctcatg
     2761 aaggcatgaa atgtggtgaa aatgatgaat atttgagtgc tttttcttaa taagtataac
     2821 cttaaacatc agctaataca cctggtgtgc attttcagtc aggatacctt aatcctcatt
     2881 tctagttgcc ttgccaatga ttccataata tactgtctca ttactgttta tttttactgt
     2941 tgtgtaaaat tgtggtataa tgagaaatac atttggtctt tgttcctggt tcctggcata
     3001 gagctcctaa aacgcttaga atttcatgag tgataagagt tttttggttt tgttttgttt
     3061 ttgctgttgt tgttattcat agcactgccc ttttaattac acctgattat actactgaag
     3121 tgacttatgg ttgctcccct agacagcctc agaatggggc tgttctctag gaagatcaag
     3181 taactagagg atggagactt tgtgccccat ttctcccacc tcctggaagg ggaggggtgc
     3241 tggagattag attagacaat gagattaaga gaactccaaa tagcccaaga gggtggtgca
     3301 cccccaactt cataggggta gaggctcctg agattaggag aacccttttt aggctttact
     3361 ctatgtacct cttcatttga gtgttcattt gcgtccttta taaccagtaa aacaaagtac
     3421 gctgttttct tgagttttgt gagccctgta gcaaattatc aaacctgagt agggcagtgg
     3481 gaactcggaa tttatcacca ttcagaactg caggttgtcc ttgtgagtgg catctgatgt
     3541 gggggaagtc ttggactgag ccccttaact tgtggagtct gcactaattt agactgcact
     3601 aactaacttg cactgcacta acttggactg cactaacttg tggagtctgc actaacttgg
     3661 agaagttagt gtcagaattg aattatagaa cacccagttg ttcagaattg aattgtagaa
     3721 cacccaattg gtgtgggaga attagagaat ttatttgtgt cagaaaatac tccagaacaa
     3781 ccaccccata ttatgattag ctcttttcct ttctttggct ctgagcttaa ttgtacatta
     3841 agcaaactta agtagaaaag aaactgaata tgttaaatat attaacaaca tatttggact
     3901 tgcttaacta agattataga gatgatcagt ttataaaacc accttcaact taaataaatt
     3961 tgaactcgaa attgcaaaag cagtctagag gctttgctag tatccttcaa ccaatttcta
     4021 gtaaaaatat cctatataac cataattatc aaaaccagaa aaacaacatt ggtaggatac
     4081 tataaagtac taatcttatt ttggatttga cgaattttta catgtttttt tcttttttag
     4141 tttgtactct aagaagttgt attacatgta cagattcgtg taaccactgc aaccacataa
     4201 aactaatgaa cacaaagtcc ctcatgctac ctttttatgc ttacactcca tccaaaccta
     4261 actctgccaa ccacttttct cctatcagta taatttcatc atttcatgaa tatgataaaa
     4321 ataaaattgt ttttgtaaat ggtttttata aattttatat aaataagtta tatgaatttt
     4381 tattgataga gagtatgtaa gcttttggca tttttgtcac tcagcaaatt actcctaagg
     4441 tttatatgag ttgatgaata gttgttttat tatttttttt taccaccatg tatctaacca
     4501 gatgaaagtt gtttatattt gagagtagta tacatatttg atgtagtagt ttatccattc
     4561 acctatgaga tatatttgca ctgttttcct ggttttaagt gctataaata aagatgctgt
     4621 gaaatcta
//
