LOCUS       NM_001161499            4507 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 611 (ZNF611), transcript variant
            2, mRNA.
ACCESSION   NM_001161499
VERSION     NM_001161499.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4507)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA245006.1, DA726181.1, DA226106.1, AC022150.6 and BC028590.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001161499.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1, 2 and 3 encode the same isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DB194575.1, SRR1803613.193223.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000652185.1/ ENSP00000498713.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                DA245006.1         11-43
            34-106              DA726181.1         1-73
            107-107             DA226106.1         112-112
            108-610             DA726181.1         75-577
            611-4254            AC022150.6         212626-216269       c
            4255-4507           BC028590.1         4547-4799
FEATURES             Location/Qualifiers
     source          1..4507
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.41"
     gene            1..4507
                     /gene="ZNF611"
                     /note="zinc finger protein 611"
                     /db_xref="GeneID:81856"
                     /db_xref="HGNC:HGNC:28766"
     exon            1..44
                     /gene="ZNF611"
                     /inference="alignment:Splign:2.1.0"
     exon            45..144
                     /gene="ZNF611"
                     /inference="alignment:Splign:2.1.0"
     exon            145..246
                     /gene="ZNF611"
                     /inference="alignment:Splign:2.1.0"
     exon            247..328
                     /gene="ZNF611"
                     /inference="alignment:Splign:2.1.0"
     CDS             266..2383
                     /gene="ZNF611"
                     /note="isoform a is encoded by transcript variant 2"
                     /codon_start=1
                     /product="zinc finger protein 611 isoform a"
                     /protein_id="NP_001154971.1"
                     /db_xref="CCDS:CCDS12855.1"
                     /db_xref="GeneID:81856"
                     /db_xref="HGNC:HGNC:28766"
                     /translation="MLREEAAQKRKGKEPGMALPQGRLTFRDVAIEFSLAEWKCLNPS
                     QRALYREVMLENYRNLEAVDISSKCMMKEVLSTGQGNTEVIHTGTLQRHESHHIGDFC
                     FQEIEKEIHDIEFQCQEDERNGLEAPMTKIKKLTGSTDQHDHRHAGNKPIKDQLGSSF
                     YSHLPELHIFQIKGEIGNQLEKSTNDAPSVSTFQRISCRPQTQISNNYGNNPLNSSLL
                     PQKQEVHMREKSFQCNKSGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHEQYLAC
                     HDRCHTVEKPYKCKECGKTFSQESSLTCHRRLHTGVKRYNCNECGKIFGQNSALLIDK
                     AIDTGENPYKCNECDKAFNQQSQLSHHRIHTGEKPYKCEECDKVFSRKSTIETHKRIH
                     TGEKPYRCKVCDTAFTWHSQLARHRRIHTAKKTYKCNECGKTFSHKSSLVCHHRLHGG
                     EKSYKCKVCDKAFVWSSQLAKHTRIDCGEKPYKCNECGKTFGQNSDLLIHKSIHTGEQ
                     PYKCDECEKVFSRKSSLETHKIGHTGEKPYKCKVCDKAFACHSYLAKHTRIHSGEKPY
                     KCNECSKTFSHRSYLVCHHRVHSGEKPYKCNECSKTFSRRSSLHCHRRLHSGEKPYKC
                     NECGNTFRHCSSLIYHRRLHTGEKSYKCTICDKAFVRNSLLSRHTRIHTAEKPYKCNE
                     CGKAFNQQSHLSRHHRIHTGEKP"
     exon            329..455
                     /gene="ZNF611"
                     /inference="alignment:Splign:2.1.0"
     exon            456..4507
                     /gene="ZNF611"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4484..4489
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF611"
                     /note="hexamer: ACTAAA"
     polyA_site      4507
                     /gene="ZNF611"
                     /note="major polyA site"
ORIGIN      
        1 aaacccggaa gcggatcggg tggagtgtag gtcatatcgc cgcgttgact agataacgaa
       61 ggacaatgca tatatacaaa attgctgtat tgcctggtga tatgcagctg tacctgtgac
      121 atcataattg caccctccga catgatatct cttccaaatg cttgatgaaa aaggtgggag
      181 gatcacttga gccagggagt tgaaggctgc agtgagccct gtttttgcca ccacactcca
      241 gcttgggatt gattcctaaa gactcatgtt acgtgaggaa gcagctcaga agaggaaagg
      301 aaaggagcca ggcatggctc ttcctcaggg acgcttgact ttccgggatg tggctataga
      361 attctcattg gcagagtgga aatgcctgaa cccttcacag agggctttgt acagggaagt
      421 gatgttggag aactacagga acctggaggc tgtggatatc tcttccaaat gcatgatgaa
      481 ggaggtcttg tcaacagggc aaggcaatac agaagtgatc cacacaggga cattgcaaag
      541 acatgaaagt catcacattg gagatttttg cttccaggaa attgagaaag aaattcatga
      601 cattgagttt cagtgtcaag aagatgaaag aaatggcctt gaagcaccca tgacaaaaat
      661 aaaaaagttg actggtagca cagaccaaca tgatcacagg catgctggaa acaagcctat
      721 taaagatcag cttggatcaa gcttttattc acatctgcct gaactccaca tatttcagat
      781 caaaggtgaa attggtaatc aacttgagaa gtctactaat gatgctccct cagtttcaac
      841 attccaaaga atttcctgta ggccccaaac ccagatttct aataactatg ggaataatcc
      901 cctgaattct tcattactcc cacaaaaaca ggaagtacac atgagagaaa aatctttcca
      961 atgtaataag agtggcaaag cctttaattg tagctcactc ttaaggaaac accagatacc
     1021 ccatttagga gacaaacaat ataaatgtga tgtatgtggc aagctcttta atcacgagca
     1081 ataccttgca tgccatgata gatgtcacac tgttgagaaa ccttacaagt gtaaagagtg
     1141 tggcaagacc ttcagtcagg agtcatccct tacctgccat cgtagacttc atactggagt
     1201 aaaacgttac aattgtaatg agtgtggcaa gatctttggt caaaattcag cccttctaat
     1261 tgataaggca attgatactg gagaaaatcc ttacaagtgt aatgaatgtg acaaggcttt
     1321 taatcaacaa tcacaacttt cacatcatag aattcatact ggagagaaac cttacaaatg
     1381 tgaagaatgt gacaaagttt tcagtcggaa atcaaccatt gagacacata agagaattca
     1441 tactggagag aaaccataca gatgtaaggt ttgtgacaca gctttcacgt ggcattcaca
     1501 gctggctcga catagaagaa ttcatactgc aaagaaaact tataaatgta atgagtgtgg
     1561 caagaccttc agtcacaagt catcccttgt atgccatcat agacttcatg gtggagagaa
     1621 atcttacaaa tgtaaggttt gtgacaaggc ttttgtgtgg agttcacaac tggcaaaaca
     1681 tactagaatt gactgtggag aaaaacctta caagtgtaat gaatgtggga agacctttgg
     1741 tcaaaattca gatcttttaa ttcataagtc aattcatact ggggagcaac cttacaaatg
     1801 tgatgaatgt gaaaaggttt tcagtcgtaa atcaagcctt gagacacata agataggtca
     1861 tactggagag aaaccataca aatgtaaggt ttgtgacaag gcttttgcgt gtcattccta
     1921 tctggcaaaa catactagaa ttcatagtgg agagaaacct tacaagtgta atgagtgcag
     1981 caagaccttc agtcacaggt cataccttgt atgccatcat agagttcata gtggtgagaa
     2041 accttacaag tgtaatgagt gcagcaagac cttcagtcgc aggtcatccc ttcattgcca
     2101 tcgtagactt catagtggtg agaaacctta caagtgtaat gagtgtggca ataccttccg
     2161 tcactgctca tcccttatat accatcgtag acttcatact ggagagaaat cttacaaatg
     2221 tacaatttgt gacaaggctt tcgtgcgtaa ttcactcctg tcaagacata ccagaattca
     2281 cactgcagag aaaccttaca agtgtaatga atgtgggaag gcttttaatc aacaatcaca
     2341 cctttcacgt catcatagaa ttcatactgg agagaaacct tagaaatgtg aagcatgtga
     2401 caaagtttcc atttggaaat cacaccttaa agacatagga gaatttatac tggagagaaa
     2461 gcttacaaat gtaaggtttc tgacaagact tgggagtgat tcacacctgg aacaacatac
     2521 tggacttcac actggagaga aaccttacaa gtgtaatgag tgtggcaaag cctttggcaa
     2581 gcagtcaaca cttattcacc atcaggcaat tcatggtgta gggaaacttg actaatgtaa
     2641 tgattgtcac aaagtcttca gtaatgctac aacgattaca aatcattgga gaatccataa
     2701 tgaagagaga tcttacaagt gtaataaatg tggcaaattt ttcagagatc gttcacatat
     2761 tgcaggtcat cggtgaactc atactggaga gaaaccttac aaatgtcatg actgtgccaa
     2821 ggtcttcagt caagcttcat cctatgcaaa acataggaga atttatacag gagagaaacc
     2881 tcacaagtgt gatgattgtg gcaaagcctt tgcttcacgt tcacacgtca ttagacatca
     2941 gagaatctat actggacaga aatcttacaa atgtcatcag tgtggcaagg tcttcagtcc
     3001 aagatcactc catgcagaac atcagaaaat tcatttttga gataaccgtt cccaatgaaa
     3061 tgagtatagc aaaccatcaa gcattaattg acattggagt caattcagca ttgacttgag
     3121 tttgtgttga cttaacattg agttcaagcc tttattgaca ttcaagtgtt tatgttaaga
     3181 ggatggggcc aggtgtggtg gctccgacct gtaatcccag cacgtcggga ggccaaggca
     3241 cataggtcac ttgaggtcag gagtttgaaa ccagcatggc caacagatgt gagccacttt
     3301 tctcagcctg ttttttgttt cttattttct attatttttt tgagccagta ctttttaaag
     3361 agatagtact tttttcagtt agtacttttt gaaagggata tatcatagta atttttaaaa
     3421 gggatatgag gccaggcacg gaggctcatg cctataatcc cagcactttg ggaggccgag
     3481 gcaggcagat cacggggtca ggagatcgag actttcctgg ctaacagggt gaatccctgt
     3541 ctctactaaa aatacaaaaa attagctggg catggtggct ggcgcctgta gtcccagcta
     3601 ctccagatgc tgaggcagga gaatggcatg aacctgtgag gcggagcttg cagggagtcg
     3661 agatcgcacc actgggctcc agcctgggcg acagagtgag agtctatctc aaaaaaaaaa
     3721 aaaaaaaaaa ggatatcaaa gcctcggtac gtggtggctc atccctgcaa tcagagtact
     3781 ttggtcgacc catgtgaact ggtcacctaa ggtcacaatt tcaaaagcac cctaacatgg
     3841 tgaaacccca tctctactaa aaatacaaaa gttagccggg ggtgttggtg tgcaccttta
     3901 gttccagcta cttgggaggc tggggcatga gaattgctta aacctaggag gtagaagttg
     3961 cagtgaacca aaattgtgcc actatactgc agcctgggtg gcagagtgag tctccatctc
     4021 aaacaaacaa aaaataacaa aaaaagacct caaaaatgct tttcttctcg tataatggac
     4081 ttccttcttt ttctttctgg ttcctcttca tttctctctt tattttttat ttatttattt
     4141 atttattttg cagtttgagt ttgagataaa tctaagttat aaaagttgta tttcttaata
     4201 cataatgact tctgaaagat gcctttgcag catcctataa tcagctcaca tcattcgttt
     4261 ctgtacttgt atattttcca gttattttcc ggttgacccc agaattcgtt agattttttt
     4321 aaaaaacaat ttcaaaatag ttgctgtttt aaattagttg catccagttc atatcaatgt
     4381 ctgcatgctt tctagtcttt gttatttatt gaaaaccttt ggtacctaaa cttaagtttg
     4441 attgtttcag tgtgtacttg gtaaatatgt cagtggcctt ttaactaaac atcaaaatgt
     4501 actttaa
//
