LOCUS       NM_001161425            2921 bp    mRNA    linear   PRI 01-AUG-2024
DEFINITION  Homo sapiens zinc finger protein 610 (ZNF610), transcript variant
            1, mRNA.
ACCESSION   NM_001161425
VERSION     NM_001161425.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2921)
  AUTHORS   Shi,Y., Cui,W., Xi,L., Liu,F., Liu,Z., Jiang,J., Liu,Z. and Cao,H.
  TITLE     Silencing of ZNF610 suppresses cell proliferation and migration in
            lung adenocarcinoma
  JOURNAL   Cell Biochem Funct 42 (4), e4078 (2024)
   PUBMED   38898665
  REMARK    GeneRIF: Silencing of ZNF610 suppresses cell proliferation and
            migration in lung adenocarcinoma.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010320.10, DA133752.1, AK290888.1, BC039903.2 and DB577508.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001161425.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (a). Variants 1, 2 and 3
            encode the same isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.218643.1,
                                           SRR1803612.99171.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000403906.8/ ENSP00000383922.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 AC010320.10        179670-179671
            3-65                DA133752.1         1-63
            66-1429             AK290888.1         1-1364
            1430-1430           BC039903.2         1243-1243
            1431-2256           AK290888.1         1366-2191
            2257-2266           DB577508.1         470-479
            2267-2921           AC010320.10        210551-211205
FEATURES             Location/Qualifiers
     source          1..2921
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.41"
     gene            1..2921
                     /gene="ZNF610"
                     /note="zinc finger protein 610"
                     /db_xref="GeneID:162963"
                     /db_xref="HGNC:HGNC:26687"
     exon            1..264
                     /gene="ZNF610"
                     /inference="alignment:Splign:2.1.0"
     exon            265..502
                     /gene="ZNF610"
                     /inference="alignment:Splign:2.1.0"
     exon            503..584
                     /gene="ZNF610"
                     /inference="alignment:Splign:2.1.0"
     CDS             522..1910
                     /gene="ZNF610"
                     /note="isoform a is encoded by transcript variant 1; zink
                     finger protein"
                     /codon_start=1
                     /product="zinc finger protein 610 isoform a"
                     /protein_id="NP_001154897.1"
                     /db_xref="CCDS:CCDS12851.1"
                     /db_xref="GeneID:162963"
                     /db_xref="HGNC:HGNC:26687"
                     /translation="MLCDEEAQKRKAKESGMALPQGRLTFMDVAIEFSQEEWKSLDPG
                     QRALYRDVMLENYRNLVFLGICLPDLSIISMLKQRREPLILQSQVKIVKNTDGRECVR
                     SVNTGRSCVLGSNAENKPIKNQLGLTLEAHLSELQLFQAGRKIYRSNQVEKFTNHRSS
                     VSPLQKISSSFTTHIFNKYRNDLIDFPLLPQEEKAYIRGKSYEYECSEDGEVFRVRAS
                     LTNHQVIHTAEKPYKCTECGKVFSRNSHLVEHWRIHTGQKPYKCSECDKVFNRNSNLA
                     RHQRIHTGEKPHKCNECGKAFRECSGLTTHLVIHTGEKPYKCNECGKNFRHKFSLTNH
                     QRSHTAEKPYKCNECGKVFSLLSYLARHQIIHSTEKPYKCNECGRAFHKRPGLMAHLL
                     IHTGEKPYKCNECDKVFGRKLYLTNHQRIHTGERPYKCNACGKVFNQNPHLSRHRKIH
                     AGENSLRTLQME"
     exon            585..711
                     /gene="ZNF610"
                     /inference="alignment:Splign:2.1.0"
     exon            712..840
                     /gene="ZNF610"
                     /inference="alignment:Splign:2.1.0"
     exon            841..2921
                     /gene="ZNF610"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2243..2248
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF610"
                     /note="hexamer: AATAAA"
     polyA_site      2260
                     /gene="ZNF610"
                     /note="major polyA site"
     polyA_site      2921
                     /gene="ZNF610"
                     /note="major polyA site"
ORIGIN      
        1 gcagacccgg aagcggatcg cgtgggtaga aggtcacacc gcagcgcgtc agtttccctt
       61 tgtttagatt caatctgggc ttcccagctc ccccgcgctt ctgtacccgg gatctgagag
      121 tcaacacaga ccttgaaatc cccgcaccgc tccctccacc ccgtgtaaat tcaggcgtct
      181 ccgtgagagt ccggcgctcg cttccctgtg tgttaaaatc gctcggcgac gggtcctgtc
      241 cccgctcgtt ctgccttggg ccagacacag gagtgttgcc atgttgtcca aactggtctc
      301 gaaattctgg agtcaagcag tctgcctgcc tcgttctcca aacgtgctgg gattacaggc
      361 atgagccact acgcctggcc aagtattcgg tatttataaa atctacagta gtacacagtt
      421 atgtcgtagg ccatcacatt cggtcaccac acactcactg actcatccag agcaatttct
      481 agtcctgcaa gcgccattca tggattgact tataaacagt catgctatgt gatgaagaag
      541 cccagaagag gaaagcaaag gagtcaggga tggctcttcc tcagggacgc ttgacattca
      601 tggacgtggc catcgaattc tctcaggagg agtggaaatc cctggaccct ggacagaggg
      661 ctttatacag ggacgtgatg ttggagaact acaggaacct ggtctttctg ggaatctgtc
      721 ttcctgacct aagtattatt tccatgttga agcaaaggag agagcccttg attctgcaaa
      781 gtcaagttaa aatagtaaaa aatacagatg gaagggaatg tgtcagaagc gtgaacacag
      841 ggaggagctg tgtattggga agcaatgcag aaaacaagcc tattaaaaat caacttggat
      901 taacccttga ggcacatctg tctgaattgc agctgtttca agccggaagg aaaatttaca
      961 gaagtaatca agttgaaaag tttacaaacc atcgttcctc agtttcacca cttcaaaaaa
     1021 tttcttctag tttcacaaca cacattttta ataaatatag aaatgatctt attgatttcc
     1081 cattactccc acaagaagag aaagcataca ttagaggaaa atcttatgaa tatgaatgta
     1141 gtgaagatgg tgaagttttt agagtccgtg caagccttac taaccatcaa gtaatccata
     1201 ctgcagagaa accttacaaa tgtactgaat gtggcaaggt cttcagtcgc aattcacacc
     1261 ttgtagaaca ttggagaatt catactggac agaagcctta caaatgtagt gaatgtgaca
     1321 aggtgtttaa tcgcaattca aaccttgcac gacatcaaag aattcatact ggagagaagc
     1381 ctcacaaatg taacgaatgt ggcaaagctt ttagagagtg ttcgggactt actacccatc
     1441 ttgtaatcca tactggagag aaaccttaca aatgtaatga gtgtggcaag aacttcaggc
     1501 acaaattttc tctaaccaat catcagagaa gtcacacggc ggaaaaacct tacaaatgta
     1561 atgaatgtgg caaggtcttt agtctgcttt cataccttgc acggcatcaa ataattcata
     1621 gtacagagaa gccctacaaa tgtaacgaat gtggaagagc atttcacaag cgtccgggcc
     1681 ttatggccca tcttctaatc catactggag agaaacctta caaatgtaat gaatgtgaca
     1741 aagtctttgg gcgcaaatta tacctaacca accatcagag aattcatact ggagagagac
     1801 cttacaagtg taatgcatgt ggcaaggtct tcaatcaaaa tccacacctt tcacgacatc
     1861 ggaaaattca tgctggagag aattcactgc gtaccttaca gatggaatga atgtggcaaa
     1921 atctttagtt agaattcaca cctagcacaa cattggagga ctcaggagaa aaaccttaca
     1981 aatatcataa atgtggcaaa gaatttagtt tgcattgaag cctcatcact catctcttga
     2041 tccacactga aaggaaaccc tacaaatgta aagttaataa catatataaa taatctataa
     2101 agagagaaca gttatatcag aatagagcat ttaatgaaaa ctaccagtat agcatattct
     2161 tgagtaggat tcacatttaa ctgctggcac cgtaatttgt aactctttga tttagaatgt
     2221 acatacttct catgttttaa gtaataaagt ttaaagtttt tttttagttt tttctttttt
     2281 ttttgagacg aagtctcgct gtattaccca ggctggagtg cagtggcatg atcttggctc
     2341 actgcaacct ccgtctcccg gattcaagca attctcctgc ctcagcctcc tgagtagctg
     2401 ggattacagg catgtgccac tactgcccgg ctaatttttg tatttttagt cgagacgggg
     2461 tttccctccg ttggccaggc cggtttcaaa ctcctgacct caagtgatcc actggccttg
     2521 gcctcccaaa gtgctgggat tataggtgtg agccacagcg cccggcctag tttaaatttt
     2581 tcttagtgtg aatgaattac atcctttcta ccagcgttgt ttaatcttac ctcaggagga
     2641 tactttatag tagagaataa taacccatta tgattttaag gttgaagcag ccagaaaagt
     2701 gtgtgtgtgt gtatgtgtgt gagacataaa acaacatacg cttctgggtg caatatactt
     2761 aagtaagtat gatgttgagt aattacactt agtacttgag ttagtttctc tgtactctgg
     2821 tgtaggatgt ttatgtgggt aaagtcaaaa tcactttaat agtacaattt cagccttgta
     2881 caccctcaaa tgtgtgtgag tgttaaagag tatgccctgt a
//
