LOCUS       NM_001007248            3102 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 599 (ZNF599), mRNA.
ACCESSION   NM_001007248 XM_086046
VERSION     NM_001007248.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3102)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK055225.1 and AC020910.7.
            
            On Nov 22, 2018 this sequence version replaced NM_001007248.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK055225.1, SRR1803611.15021.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA1970526
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000329285.13/ ENSP00000333802.6
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3101              AK055225.1         1-3101
            3102-3102           AC020910.7         159928-159928       c
FEATURES             Location/Qualifiers
     source          1..3102
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.11"
     gene            1..3102
                     /gene="ZNF599"
                     /note="zinc finger protein 599"
                     /db_xref="GeneID:148103"
                     /db_xref="HGNC:HGNC:26408"
     exon            1..392
                     /gene="ZNF599"
                     /inference="alignment:Splign:2.1.0"
     CDS             375..2141
                     /gene="ZNF599"
                     /codon_start=1
                     /product="zinc finger protein 599"
                     /protein_id="NP_001007249.1"
                     /db_xref="CCDS:CCDS32991.1"
                     /db_xref="GeneID:148103"
                     /db_xref="HGNC:HGNC:26408"
                     /translation="MAAPALALVSFEDVVVTFTGEEWGHLDLAQRTLYQEVMLETCRL
                     LVSLGHPVPKPELIYLLEHGQELWTVKRGLSQSTCAGEKAKPKITEPTASQLAFSEES
                     SFQELLAQRSSRDSRLGQARDEEKLIKIQEGNLRPGTNPHKEICPEKLSYKHDDLEPD
                     DSLGLRVLQERVTPQDALHECDSQGPGKDPMTDARNNPYTCTECGKGFSKKWALVRHQ
                     QIHAGVKPYECNECGKACRYMADVIRHMRLHTGEKPYKCIECGKAFKRRFHLTEHQRI
                     HTGDKPYECKECGKAFTHRSSFIQHNMTHTREKPFLCKECGKAFYYSSSFAQHMRIHT
                     GKKLYECGECGKAFTHRSTFIQHNVTHTGEKPFLCKECGKTFCLNSSFTQHMRIHTGE
                     KPYECGECGKAFTHRSTFIRHKRTHTGEKPFECKECGKAFCDSSSLIQHMRIHTGEKP
                     YECSECGKAFTHHSVFIRHNRTHSGQKPLECKECAKAFYYSSSFTRHMRIHTGEKPYV
                     CRECGKAFTQPANFVRHNRIHTGEKPFECKECEKAFCDNFALTQHMRTHTGEKPFECN
                     ECGKTFSHSSSFTHHRKIHTRV"
     exon            393..519
                     /gene="ZNF599"
                     /inference="alignment:Splign:2.1.0"
     exon            520..615
                     /gene="ZNF599"
                     /inference="alignment:Splign:2.1.0"
     exon            616..3102
                     /gene="ZNF599"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3079..3084
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF599"
                     /note="hexamer: AATAAA"
     polyA_site      3102
                     /gene="ZNF599"
                     /note="major polyA site"
ORIGIN      
        1 cggcgtccag tcttcgtccg ccgttaggtt gcggctgctg tggttgccaa cgctacactg
       61 ggtagaacgc cagacagggg ccacttttcg agaccgagta gagacggaca gtgaggagga
      121 taggacccac ttacacgctt ttatgtcagc cgcgatccca cccccacaag cgtctgcaaa
      181 acccttcctg gggccttggc gacagccctg tgtcctcacg gcgcgcagag gcggcgccgc
      241 gaaccttgtg tgcattttac acgacggcgg ggactgaggt ccctcgcagc ccagagccgg
      301 agcccggggt cggccgagcc cgcaggaccg gcttcctcgc cgactctcac ggcctcaccc
      361 agccccctgg gcccatggcg gcgccggcgt tggcattagt atcatttgaa gacgtggttg
      421 tgaccttcac tggagaggaa tgggggcacc tggacctggc ccagaggacc ctgtaccagg
      481 aggtgatgct ggagacctgc aggctcctgg tctcactggg gcatcctgtt cccaaaccag
      541 agctgatcta tctactggaa catggacagg aactgtggac agtgaagaga ggcctctccc
      601 aaagcacctg cgcaggtgaa aaagcaaaac ccaagattac agagcctact gcttctcagc
      661 tggccttctc tgaggaatcc tctttccagg aacttctggc acagagatcc tcaagagatt
      721 ccaggttggg gcaagctaga gatgaggaaa agctaataaa aattcaggaa gggaacttga
      781 ggccaggaac aaacccccac aaagagatat gccctgagaa gttgagttat aaacatgatg
      841 atttggagcc agatgatagt ctgggcttaa gggttttaca ggaacgagtc actccacaag
      901 atgctctcca tgagtgtgac tctcaaggac caggaaaaga ccccatgact gatgcaagga
      961 ataaccctta cacatgcacg gaatgtggga aagggtttag caagaagtgg gcccttgttc
     1021 ggcatcaaca gattcatgct ggagtgaagc cctatgagtg caatgagtgt gggaaagcct
     1081 gtcgttatat ggctgatgtc attcgacata tgaggcttca tactggggaa aaaccataca
     1141 agtgtattga gtgtgggaaa gccttcaaac gcaggtttca cctcacggag caccagcgta
     1201 ttcacaccgg agataagccc tatgagtgca aagaatgtgg caaagcattc acccaccgct
     1261 cttcttttat ccagcataat atgactcaca ctcgagaaaa acccttttta tgcaaagaat
     1321 gtgggaaagc tttttactac agctcctcat ttgctcaaca tatgaggatt catactggaa
     1381 agaaactcta tgagtgcggt gaatgtggaa aggccttcac gcaccgctcc acatttatcc
     1441 agcacaatgt gacccacaca ggagaaaaac catttttatg taaagaatgt ggaaaaacct
     1501 tttgcctcaa ctcatccttc actcagcaca tgaggattca cactggagag aaaccctatg
     1561 agtgcggtga atgtggaaag gcctttactc atcgctccac tttcatccga cataagagga
     1621 cccataccgg agagaagccc tttgagtgca aagaatgtgg gaaggccttt tgtgacagct
     1681 cttccttaat tcaacatatg aggattcaca ctggtgagaa gccttatgag tgcagtgaat
     1741 gtggaaaggc ttttacacac cactctgttt ttattcgaca taataggacc cacagtggac
     1801 aaaaaccctt ggagtgcaaa gaatgtgcaa aagcctttta ctatagctct tccttcactc
     1861 gacacatgag gattcacact ggagagaagc cctatgtttg tagagaatgt ggaaaggctt
     1921 ttacccaacc tgcaaatttt gttcggcata ataggatcca cactggagaa aaaccttttg
     1981 aatgcaaaga atgtgagaaa gccttctgtg acaactttgc tttaactcag cacatgagaa
     2041 ctcacactgg agagaaaccc tttgaatgca atgaatgtgg aaagaccttc agccacagtt
     2101 catcgttcac tcaccatcga aagattcata ccagagttta aaagatacag gaaggcctat
     2161 tacaagtgtg tttgtcttta gtgaactcat agtggtgaca tacctttcct tttgagtata
     2221 actattgagg gaaatatttt ggccagagag atgtcttagt atctgataat ttatactaac
     2281 tagaaacaga attgtccctg tgaaatcttt ttatggcagg taatcacttg tcatccaaag
     2341 aattatatta aagattcacc cagtttagag ccttacactg tacctgagaa taatcgaggg
     2401 gagagacctg gtggttaaca tgcatttagg taaaatgtca ggaacaactt tcctcttatt
     2461 aatactataa atccatctca agcatatttt aaaataatga gagatggagg aaacaatcta
     2521 gaagataaaa gaaaaagatg tgcataactt gttttcagtt tccctgttta tgacagtttg
     2581 tcatttggcg ggttggggga tggagcaggg aataagacat tgaaaaagtc tcatcccctt
     2641 tgtgtgtttt acatatatat atctctaagt ccagagccag gagagttgga ccattgaggg
     2701 cagctctgcc aacatttagt aaaagtattc attgttccaa aactgtcatc tctacccttg
     2761 agggagtgtg tctttgtgag aaatataaag gcttgagtca tgaaatactt aacacatgtg
     2821 cacatgtaca catgtacatt tatatgcagt gaattgttac tcgtggtagt taggttctgt
     2881 gaattttctg tgcacactga attagtgaat gctgaatgat tgttgctagg ggaaatacag
     2941 cgttagcttc tgtgagcctc tgatccaaac atttttatca accagtcaac acataacctt
     3001 cttctatggg tatttgtttg tttgtttgtt taaagacact ttatcagtgt ttcttgaata
     3061 attataatta ttctttataa taaaaatatt ttaattatag ca
//
