LOCUS       NM_032530               4863 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens zinc finger protein 594 (ZNF594), mRNA.
ACCESSION   NM_032530 XM_290737 XM_940636
VERSION     NM_032530.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4863)
  AUTHORS   Zouboulis,C.C., Nogueira da Costa,A., Fimmel,S. and Zouboulis,K.C.
  TITLE     Apocrine glands are bystanders in hidradenitis suppurativa and
            their involvement is gender specific
  JOURNAL   J Eur Acad Dermatol Venereol 34 (7), 1555-1563 (2020)
   PUBMED   32031713
REFERENCE   2  (bases 1 to 4863)
  AUTHORS   Abrink,M., Aveskogh,M. and Hellman,L.
  TITLE     Isolation of cDNA clones for 42 different Kruppel-related zinc
            finger proteins expressed in the human monoblast cell line U-937
  JOURNAL   DNA Cell Biol 14 (2), 125-136 (1995)
   PUBMED   7865130
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA448705.1, BX472376.1, AB058774.2, AK131271.1, AC087500.16 and
            AC012146.25.
            
            On Nov 22, 2018 this sequence version replaced NM_032530.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660805.125900.1,
                                           SRR1660805.31344.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2467146 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000575779.2/ ENSP00000461032.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-101               DA448705.1         16-116
            102-621             BX472376.1         113-632
            622-1799            AB058774.2         622-1799
            1800-2840           AK131271.1         986-2026
            2841-2929           AB058774.2         2841-2929
            2930-2930           AC087500.16        141192-141192
            2931-4045           AB058774.2         2931-4045
            4046-4320           AK131271.1         3233-3507
            4321-4862           AB058774.2         4321-4862
            4863-4863           AC012146.25        1552-1552
FEATURES             Location/Qualifiers
     source          1..4863
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17p13.2"
     gene            1..4863
                     /gene="ZNF594"
                     /note="zinc finger protein 594"
                     /db_xref="GeneID:84622"
                     /db_xref="HGNC:HGNC:29392"
     exon            1..121
                     /gene="ZNF594"
                     /inference="alignment:Splign:2.1.0"
     exon            122..4863
                     /gene="ZNF594"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..2565
                     /gene="ZNF594"
                     /note="zinc finger protein HZF18"
                     /codon_start=1
                     /product="zinc finger protein 594"
                     /protein_id="NP_115919.1"
                     /db_xref="CCDS:CCDS42241.1"
                     /db_xref="GeneID:84622"
                     /db_xref="HGNC:HGNC:29392"
                     /translation="MKEWKSKMEISEEKKSARAASEKLQRQITQECELVETSNSEDRL
                     LKHWVSPLKDAMRHLPSQESGIREMHIIPQKAIVGEIGHGCNEGEKILSAGESSHRYE
                     VSGQNFKQKSGLTEHQKIHNINKTYECKECEKTFNRSSNLIIHQRIHTGNKPYVCNEC
                     GKDSNQSSNLIIHQRIHTGKKPYICHECGKDFNQSSNLVRHKQIHSGGNPYECKECGK
                     AFKGSSNLVLHQRIHSRGKPYLCNKCGKAFSQSTDLIIHHRIHTGEKPYECYDCGQMF
                     SQSSHLVPHQRIHTGEKPLKCNECEKAFRQHSHLTEHQRLHSGEKPYECHRCGKTFSG
                     RTAFLKHQRLHAGEKIEECEKTFSKDEELREEQRIHQEEKAYWCNQCGRNFQGTSDLI
                     RHQVTHTGEKPYECKECGKTFNQSSDLLRHHRIHSGEKPCVCSKCGKSFRGSSDLIRH
                     HRVHTGEKPYECSECGKAFSQRSHLVTHQKIHTGEKPYQCTECGKAFRRRSLLIQHRR
                     IHSGEKPYECKECGKLFIWRTAFLKHQSLHTGEKLECEKTFSQDEELRGEQKIHQEAK
                     AYWCNQCGRAFQGSSDLIRHQVTHTREKPYECKECGKTFNQSSDLLRHHRIHSGEKPY
                     VCNKCGKSFRGSSDLIKHHRIHTGEKPYECSECGKAFSQRSHLATHQKIHTGEKPYQC
                     SECGNAFRRRSLLIQHRRLHSGEKPYECKECGKLFMWHTAFLKHQRLHAGEKLEECEK
                     TFSKDEELRKEQRTHQEKKVYWCNQCSRTFQGSSDLIRHQVTHTREKPYECKECGKTQ
                     SELRPSETS"
     regulatory      4842..4847
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF594"
                     /note="hexamer: AATAAA"
     polyA_site      4863
                     /gene="ZNF594"
                     /note="major polyA site"
ORIGIN      
        1 accggaagtt ctcgcctggc ccaggcgcgg ggtccaagat ggtggcgcta ggagccgcga
       61 cccagtgata gcggccgtgg aggggccccc gaccgagcgg gaggttgggg gtagcctgga
      121 gattctgaag acaggaataa gatgaaggaa tggaaatcaa agatggaaat ttctgaagaa
      181 aagaagtcag caagggctgc atccgaaaaa ctccaaagac aaatcaccca ggaatgtgag
      241 ttagttgaaa ccagtaattc tgaggacaga ttattgaagc actgggtaag ccctttaaag
      301 gatgcaatga gacatctccc ttcccaagag agcggtatca gggaaatgca tattatcccc
      361 cagaaagcca ttgtgggaga gattggccat ggatgtaatg aaggagaaaa aatactttct
      421 gcaggagaaa gctcccatag atatgaggtt agtggccaaa acttcaaaca gaagtcagga
      481 ttaactgaac atcagaaaat tcataatata aataagacct atgaatgtaa ggaatgtgaa
      541 aaaaccttca acaggagttc aaacctgatc atacatcaga gaattcatac aggaaataag
      601 ccatatgtgt gtaatgaatg tgggaaagac tctaatcaaa gttcaaatct tattatacat
      661 cagagaattc atacaggaaa gaaaccttat atatgtcatg aatgtggaaa agacttcaat
      721 cagagctcca atctggtgag acataagcaa attcacagtg gtgggaatcc ctatgagtgc
      781 aaagagtgtg ggaaggcttt taagggaagc tcaaaccttg tcctgcacca gagaatccac
      841 agtaggggga agccatattt atgcaataaa tgtgggaagg ctttcagtca aagcacagat
      901 cttattatac atcacagaat tcacactgga gagaaaccct atgaatgtta tgactgtgga
      961 cagatgttca gtcaaagttc acaccttgtc ccacatcaga gaattcacac tggagagaaa
     1021 cccctcaaat gtaatgaatg tgaaaaagcc ttcaggcagc attctcacct tactgaacac
     1081 cagagactcc acagtggaga gaaaccctat gaatgtcaca gatgtgggaa gaccttcagt
     1141 gggcgcacag cttttcttaa acatcagaga ttgcatgctg gagagaaaat tgaagaatgt
     1201 gagaaaacct tcagcaagga tgaggagctt agggaagagc agagaattca ccaggaagag
     1261 aaagcttatt ggtgtaatca gtgtggtagg aatttccagg gcacctcaga cctcatcaga
     1321 catcaggtaa ctcatacagg agagaaacca tatgaatgta aagaatgtgg gaaaactttc
     1381 aatcagagct cagaccttct gagacatcat agaattcaca gtggagaaaa accttgtgta
     1441 tgtagcaaat gtgggaaatc ttttaggggc agctcagatc ttattagaca ccatcgtgtt
     1501 catactggag agaaacccta tgaatgtagt gaatgtggga aagcctttag ccagaggtca
     1561 caccttgtta cacaccagaa aatccatact ggagagaagc cctatcagtg cactgaatgt
     1621 gggaaagcct tcaggcggcg ttcactcctt attcaacatc ggagaattca tagtggtgag
     1681 aaaccctatg aatgtaagga atgtgggaag ctcttcattt ggcgcacagc tttcctcaaa
     1741 catcagagcc tgcatactgg agagaaactt gaatgtgaga aaaccttcag ccaggatgag
     1801 gagcttaggg gagagcagaa aattcaccag gaagcgaaag cttattggtg taatcagtgt
     1861 ggtagggctt tccagggcag ctcagacctc atcagacatc aggtaactca tacaagagag
     1921 aaaccatatg aatgcaaaga atgtgggaaa actttcaatc agagctcaga ccttctgaga
     1981 catcatagaa ttcacagtgg agaaaaacct tatgtatgca acaaatgtgg gaaatctttt
     2041 aggggtagct cagatcttat taaacaccat cgtattcata ctggagagaa accctatgaa
     2101 tgtagtgaat gtgggaaagc cttcagccag aggtcacacc ttgctacaca ccagaaaatc
     2161 catactggag agaaacccta tcagtgcagt gaatgtggga atgccttcag gcggcgttcc
     2221 ctccttattc aacatcggag acttcatagt ggtgagaaac cctatgaatg taaggaatgt
     2281 gggaaactct tcatgtggca cacggctttc ctcaaacatc agagactgca tgctggagag
     2341 aaacttgaag aatgtgagaa aaccttcagc aaggatgagg agcttagaaa agagcagaga
     2401 actcaccagg aaaagaaagt ttattggtgt aatcagtgta gtaggacctt ccagggcagc
     2461 tcagatctca tcagacatca ggtaactcat acaagagaga aaccatatga atgtaaagaa
     2521 tgtgggaaaa ctcaatcaga gctcagacct tctgagacat catagaattc acagtggaga
     2581 aaaaccttac gtatgcaata aatgtgggga atcttttagg agcagctcag atcttattaa
     2641 acaccatcgt gttcatactg gagagaaacc tcatgaatgt agtgaatgtg ggaaagtctt
     2701 tagccagagg tcccaccttg tcacacacca gaaaatccac actggagaga agccctatca
     2761 gtgcactgaa tgtgaaaaag ccttcaggcg gcgttcactc cttattcaac gtcggagaat
     2821 tcatagtggt gagaaaccct atgaatgtaa ggaatgtggg aaactcttca tgtggcacac
     2881 agctttcctc aaacatcaga gactgcatgc tggagagaaa cttgaagaac gtgagaaaac
     2941 cttcagcaag gatgaggagc ttaggggaga gcagaaaatt caccaagaag agaaagctta
     3001 ttggtgtaat cagtgtggta gggctttcca gggcagctca gacctcatcg gacatcaggt
     3061 aactcataca ggagagaaac catatgaatg taaagaatgt gggaaaactt tcaatcagag
     3121 ctcagacctt ctgagacatc atagaattca cagtggagaa aaaccttatg tatgcaacaa
     3181 atgtgggaaa tcttttaggg gcagctcaga tcttattaga caccatcgtg ttcatactgg
     3241 agagaaaccc tatgaatgcc ctgaatgttg gaaggccttc agtcagaact cacaccttgt
     3301 cagtcatcaa agaattcata ccagagagaa accctttgaa tgtagcaact gtggtaaggc
     3361 cttcagtggg tggacagctt ttcttaagca ccagaaactt cacattggaa aggaatttga
     3421 agactgtaag agtctacaaa caggacctat tctaataggt agcagaaacc taatgaatgc
     3481 agtaaaacta ggaaaagtct gatggagacc acatcttatt gcactacaaa tgagttttat
     3541 tagaaaaaaa ccatgggaag gtgggaaagc agagaaaata cctactggat ttttcaaacg
     3601 taagtataat caagtggaaa agccaaaagc tcttggacat aatcaccttt tttttttctg
     3661 tctcagaact gacactagaa tatggtccca acgatacaat tttttaaatt atttattttt
     3721 taacatacaa agagatgagg tctcactatg ttgcccaggc tggacttgaa ctcttgggct
     3781 caagcactcc tccctcctca gcctcccaaa gggttgggat taccggcatg agccactgca
     3841 ccagccccag gggtctaatt acttgagaat gttttaaggg atgtctatca ttattaaaat
     3901 cattataaat cactttggca acaaccccaa aactaaatta ttcatggaaa gagccatttc
     3961 aatcttgact tcctagtcga gtgacaagtt taaatgtggg aaaaaaccct gtgaaagtaa
     4021 tgagtgtagg ccaggtgcgg tggctcgtac ctgtaatcca gcactttggg aagccaaggt
     4081 gggcagatca cgaggtcacg agttgatcat gaggagttac tatgcccagc caacatacta
     4141 aaaccccgtc tctactaaaa ataacaaaaa ttagccaggc atggtggggc acgcctgtag
     4201 tcccaggtac ttgcgaggct agggcaggag aatcacttga acctgggagg tggaggttgc
     4261 ggtgagccaa gatcatgcca ctgcactcca gcctgggcaa caagtgcgaa actccatctc
     4321 aaaaaaaaaa aaaagtctaa ctcttctgct tgtctttaca atgctgtaca gtgagagcta
     4381 atgtttataa ggataaacag gatacttaca gggatttgaa ggtaatttaa ttcagtggtt
     4441 tccaactttt taatcaccaa ggccttcttt ttactcccct atgtcctgtg tcttaaaaga
     4501 ttatgtttac caaactgcat ttattaaaga attatatttt gctacataaa ggcatgtaca
     4561 acacaaatca tgcttctgac tggcaccatg taggcagacc taggtactaa aattccagcc
     4621 caaagcaaat aatttaccat tttcattagt ctttttattc cttttgtggg caaacatatc
     4681 gtctatgtta ggctttttga aatattaact atgacttgta aactccagat taaaaactaa
     4741 ccaattcatc tttgatggag cttgaatcaa actaagggta ttggactttt gaaagattga
     4801 aatttttgtt acagtatgga atgtttttaa ctgaatgttg aaataaaagt tatttaagaa
     4861 tta
//
