LOCUS       NM_001376223            5794 bp    mRNA    linear   PRI 16-FEB-2024
DEFINITION  Homo sapiens zinc finger protein 587B (ZNF587B), transcript variant
            1, mRNA.
ACCESSION   NM_001376223
VERSION     NM_001376223.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5794)
  AUTHORS   Petroni,D., Bartolini,E., Chiaramonte,R., Ottolenghi,S. and Comi,P.
  TITLE     Computer sequence analysis of human highly conserved zinc finger
            modules
  JOURNAL   DNA Seq 9 (3), 163-169 (1998)
   PUBMED   10520746
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010522.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11853559.17784.1,
                                           SRR18074967.965146.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000594901.2/ ENSP00000469623.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-266               AC010522.3         15458-15723
            267-393             AC010522.3         24182-24308
            394-5794            AC010522.3         25997-31397
FEATURES             Location/Qualifiers
     source          1..5794
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..5794
                     /gene="ZNF587B"
                     /note="zinc finger protein 587B"
                     /db_xref="GeneID:100293516"
                     /db_xref="HGNC:HGNC:37142"
     exon            1..266
                     /gene="ZNF587B"
                     /inference="alignment:Splign:2.1.0"
     CDS             231..2132
                     /gene="ZNF587B"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 587B isoform 1"
                     /protein_id="NP_001363152.1"
                     /db_xref="CCDS:CCDS92699.1"
                     /db_xref="GeneID:100293516"
                     /db_xref="HGNC:HGNC:37142"
                     /translation="MAVVATLRLSAQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVT
                     LENLALMSSLGCWCGVEDEAAPSKQSIYIQRETQVRTPVTGVSPKKAHPCEMCGPILG
                     DILHVADHQGTHHKQKLHRCEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFVKR
                     CKLHVSGESSVFSESGKDFLPRSGLLQQEASHTGEKSNSKTECVSPFQCGGAHYSHGD
                     SMKHFSTKHILSQHQRLLPREECYVCCECGKSFSKYVSFSNHQRVHSGKRPYECGECE
                     KSFSQKSSLIQHQQFHTGGKPYGCEECGKYFSLEGYLRRHQKVHAGKGPYECGECGKS
                     FSSNVNLKSHQRIHTGERPYKCGECEKSFSRKPSLSYHQRIHTEVRPYKCGECGKSYI
                     SKGHLRIHQRMHTGERPYKCGDCGKSFNEKGHLRSHQRVHTTERPYKCGECGKCFSHK
                     GNLILHQHGHTRKRPYMCWECGKLFKKKSHLLVHQRIHSGEKPYACEACQKFFRHKCH
                     LTAHQRVHTGERPYECSDCGKSFTHSCAFIVHKRVHTGQKPYECSECGKSFAASSYLT
                     SHRRVHTGQKPYECSECGKSFAGISSLTNHRRVHTGEKPYGCSECEKKFRKSSSLRYH
                     QRVHERKAL"
     exon            267..393
                     /gene="ZNF587B"
                     /inference="alignment:Splign:2.1.0"
     exon            394..5794
                     /gene="ZNF587B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5773..5778
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF587B"
                     /note="hexamer: AATAAA"
     polyA_site      5794
                     /gene="ZNF587B"
                     /note="major polyA site"
ORIGIN      
        1 gattggtgtt gggtttattt gtcggagagg ctcctgagcg ctaggtcggc actgcggtga
       61 ctgaacccag aaggcggaga acagttgtcc tctgctgcac agaggcgact ctggagctct
      121 gtgacggcgc caagcgtgac ccacccctgg gccaggatag ggaccgtcat gcccatatct
      181 cctggctggt caccctctcc tcccaaccct gctttaaacc acgtggttcg atggcggtgg
      241 tggccacgct gaggctctct gctcagggca cagtgacttt tgaagacgtg gctgtgaaat
      301 ttacccagga ggaatggaat ctccttagtg aggctcagag atgcctgtac cgtgatgtga
      361 ctctggagaa cctggcactt atgtcctccc tgggttgttg gtgtggagtg gaagatgagg
      421 cggcaccttc taagcagagt atttatatac aaagagagac tcaggtcagg actcctgtga
      481 caggtgtgtc tcccaagaag gcccacccct gtgagatgtg tggcccgatc ttgggagaca
      541 ttttgcatgt ggcagatcat cagggaacac atcacaagca gaaactgcac aggtgtgagg
      601 cctgggggaa taaattgtat gacagtggaa actttcatca gcaccagaat gagcacattg
      661 gagagaaacc ctacagaggg agtgttgagg aggcgttgtt tgtgaagagg tgtaagttgc
      721 atgtgtcagg ggagtcatct gtcttcagtg agagtgggaa ggactttttg cccaggtcag
      781 gattactcca gcaggaggcc agtcacactg gggagaagtc aaacagcaaa actgagtgtg
      841 tgtctccctt tcagtgtggg ggagctcact atagccatgg agattccatg aaacatttta
      901 gcaccaaaca tatactcagt cagcaccaga gacttctccc tcgagaagaa tgttatgtgt
      961 gctgtgaatg tgggaaatcc tttagcaaat atgttagctt cagtaatcat cagagagttc
     1021 acagtggaaa aagaccttat gaatgtggag aatgtgagaa atcttttagt caaaagagca
     1081 gcctcattca acatcagcaa tttcacactg gaggaaaacc ttatgggtgt gaagaatgtg
     1141 ggaaatattt tagcttagaa ggatatctta ggcgccatca aaaagttcac gctggaaaag
     1201 ggccttatga gtgtggagaa tgtgggaaat cttttagttc aaacgtgaac cttaagagtc
     1261 atcagcgcat tcacactgga gagagacctt acaagtgtgg agaatgtgag aaatctttta
     1321 gtcggaagcc cagccttagt taccatcagc gcattcacac tgaagtaaga ccttacaagt
     1381 gtggagaatg tgggaaatct tatatttcaa aggggcacct taggatccat cagcgcatgc
     1441 acactggaga aagaccttac aagtgtggag actgtgggaa atcttttaat gaaaaaggac
     1501 accttaggag tcatcagcga gttcacacta cagaaagacc ttataagtgt ggggaatgtg
     1561 ggaaatgttt tagtcacaag ggtaacctca ttctacacca gcatggccat actagaaaaa
     1621 ggccttatat gtgttgggaa tgtggaaaat tatttaagaa gaagtctcac ctccttgtac
     1681 accagagaat tcacagtgga gagaagccat atgcttgtga ggcttgtcag aaatttttta
     1741 ggcacaagtg ccacctcact gcacaccaga gagttcacac tggagaaagg ccatatgaat
     1801 gcagtgattg tgggaagtca tttacccaca gctgtgcatt cattgttcat aagagagttc
     1861 acactggtca gaagccttat gagtgcagtg aatgtgggaa atcttttgct gcaagctcct
     1921 atctcactag tcacaggaga gttcacactg gtcagaagcc ttatgagtgc agtgaatgtg
     1981 ggaaatcttt tgctggaatc tccagtctca ctaatcacag gagagttcac actggagaaa
     2041 agccttatgg gtgtagtgaa tgtgaaaaaa aatttaggaa aagctcttca cttcgttacc
     2101 atcagagagt tcatgaaaga aaggccttat gagtgcagag aatgagtcca gtctcattaa
     2161 atacaggaga gcacacacct gagtaagatc ttgtgattgc agcaaatgtg gaaaatgttt
     2221 acccaaaaga agtctgctct ccttggacat tggagagttc acaccagaga aaagtcctta
     2281 caagtaaaat aaatttggca gttttgtagc cacacctctg tattccttca ggattatatt
     2341 taacactgaa tgaaggcctt actagtgtgg caaatatagg ctatttatcc agaagtctgg
     2401 cttcaaaact cacaggagag ctgtcactac ggaaatgcct tttgaatgta atgtttgcaa
     2461 aaaagcactg tgccttctgt cattgaatcc tagaacactg agatgagaaa aacactgtag
     2521 atgtataggt tagatatata gggaatgtta ttattttttc ctttttttgg agagacggtc
     2581 tcactccatc acccatgctg gtgtgcagtg ctgcgatcgt agctcactgc atcctccgcc
     2641 ccctaggctc aagtgatctt cccaccttag cctccatgta gctgggtcca caggcatgca
     2701 ccaccatgcc tggctatttt ctcatattag tagatatagg gttttaccat gtttccaggc
     2761 tggtatcgaa ctcctgagct caagcaatct gtacacctca gcctcccaaa gtgctgagat
     2821 tgtaggtttg agtcactgtg ctcagccaat tatgtttttc tgtgtaacat gggaggagat
     2881 cctttgaggg caccatgtgc ccaaattgaa aaaactccag gcatgtggca tctgtattat
     2941 attttttact atgccctgtt atcttgctag acttatgtga ctgccactta tctggcaaaa
     3001 gccattacat ctcagctact tggtaggtac ccacattgca tcattcacct atttcgtatt
     3061 ctagaagtat attttggttg tctcccattc acgagagatt ttttttttaa gttttttgtt
     3121 tggttggttg gttggttggt tggttgtttt tttttgtttt tttttttttt ttttttggag
     3181 acaaagtttc actgtcaccg atactggagt gcagtggtgt gatcctggtt cattgcaacc
     3241 tctgcctcct gagttcaagc aattctcctt tctcagcctc ctgagtagct gggattacag
     3301 gtgcctgcca ccacacccag gtaatttttg tacttttagt agagatgggg tttcactatg
     3361 ttggtcaaac tgatcttgaa ctcctaacct cgtgatccac ctgccttggc ctcccaaagt
     3421 gctgggatta cagtgtgagc ctctgcttct ggccttttta aaaatttttt aaatttatat
     3481 tttttgtaga gacagggtct tgctgtgttg cacagtctgg tctcaaactg ctggtctcga
     3541 gtgatccttc tgcctggctt cccagaatgt tgggattata ggcgtggcat aagtcaccat
     3601 gctgggactt ttttatttct ttaattttta attccagatc tggtcacaga aggatttgtt
     3661 gagtagcctc agcacttctt gctttttcat ttctttctga taagttacac catggacctt
     3721 ccccattttt gtcccagagg actcttgtgc tgacttgaaa agatggacta ttttggctaa
     3781 gcatggtggc tcatgcctgt aatcccaaca ctttgggagg ccgaggtggg tggatcacaa
     3841 ggacaggaag gagttcaaga ccagcctggg caatatagtg aaatcctgtc tcttctaaaa
     3901 atataaaaat tagccgggca tggtggcgca cctgtagccg cagctactca ggaggctgag
     3961 gcaggaaaat tgcttgaacc ccgggaggta gaggttgcag tgagctgaga tcatgccact
     4021 gcactccagc ctgggtcctg ctaccttgaa ggacagcata gctaaactgc gtggcccaag
     4081 ggacagcatg aatgcagaat atagctttct tcacttgtgg cctatttgca tagctgccca
     4141 aggcctccag tggacgactt catggctttg tggtcttcat ctgtagcatg gatactacag
     4201 attgtgggtt cataggtcag ctgggtacag ggcagttttt ataacaacct ctggtgggtt
     4261 ttttatttta gtgtcaatat cacactgaaa gattggtgat tttttttgaa ccagacaaaa
     4321 ttctctctta tgaggtatat tgcactgtgc tcggtactgt tgagggaact ctgttcagca
     4381 gatcttacaa ggcacacatg tgccatgata tccagaattc tgtaaggcaa catcacaggt
     4441 tgtaaggcta taggatgaaa ttataatttt atggttactt agttactgca tttatagtca
     4501 gcagagggga cagcaataaa gtttttgaaa tatatctttt tttttttttt gagacacagt
     4561 ctcactctgt cacccaggct agagtgctgt tgcaccatct cggctcactg caacctgtgc
     4621 cttctgggtt caagcgattc tcccacctca gtcacccaag tagctagaat tacaggtgca
     4681 tgccaccaca ccactaatgt tttgtggttt tagtagagac gggtttcacc gtgttgcaca
     4741 gactggtctt gaattcaact cttgagctca ggtgatctgc tcacctccgc cttccaaagt
     4801 gctgggacta caggtgtggg ccgctgtgtt tggctgaaat gtatgtcttt taaaggagtg
     4861 tccacagtta tccagtcact gtgtctgtga tggataagca gatacagaaa ttctcaagac
     4921 ttccataata atgaatgttg tgtagctaag ctttggtcag aggaaataat ctaaaggttt
     4981 tgtgaattca tgtaaccttt tgggctgctc accttaaggt aactcctgta ttaacaggag
     5041 gaacagaata gggaaaaaga tctcagttca gtgatgtagc tttgtgacca gccagtgatc
     5101 cagttcaatc aggtagaaat gaccttcctg ctacatcaat atttgcttct atggaggcta
     5161 gtttccccac ttagggcatg agaagaattg gtaaagtcaa cataaaattg ccaaacctgt
     5221 caccaaaaat gatggcaaat ctgtattttt ctcttaaacc gtgttataaa agctgtaata
     5281 aggtataggc tgagcatcat ggctcatgcc tgtattccca gcactttggg aggccagatt
     5341 ccttgagacc agtgtgggga acatggcaaa accttgtctc taggaaaaat agccaggtat
     5401 ggtggcatgt accttagtct tagtgatgtg ggaggattgc ttgagcctgg gaggcagaag
     5461 ttgcagtgag ctaagattgc aacgctgcag tccagcctgg gtgatagagt gagaccccat
     5521 cttaaaaata aaataaagat ataaatgaca tccaataaag tacacatatt tgagctgtag
     5581 gataagtctt gaattttatt ataatcccgt gaaaccatca tcagagtcac cataatgaat
     5641 ttatctaatc tatcaccttt gtatttactt ggagccttta taaagttttt ctctctgctc
     5701 ttcaaacaac cattgattta ctttgctgta tgatggagta ctttccattt tctggaattt
     5761 tctgactgat gtaataaagt gtttcctctt ataa
//
