LOCUS       NM_017652               2196 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 586 (ZNF586), transcript variant
            1, mRNA.
ACCESSION   NM_017652
VERSION     NM_017652.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2196)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BP352135.1, BC051325.1 and AI962754.1.
            
            On Nov 23, 2018 this sequence version replaced NM_017652.3.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1163657.336760.1,
                                           SRR1803612.281715.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000396154.7/ ENSP00000379458.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 BP352135.1         25-30
            7-2157              BC051325.1         1-2151
            2158-2196           AI962754.1         16-54               c
FEATURES             Location/Qualifiers
     source          1..2196
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..2196
                     /gene="ZNF586"
                     /note="zinc finger protein 586"
                     /db_xref="GeneID:54807"
                     /db_xref="HGNC:HGNC:25949"
     exon            1..203
                     /gene="ZNF586"
                     /inference="alignment:Splign:2.1.0"
     CDS             168..1376
                     /gene="ZNF586"
                     /note="isoform a is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 586 isoform a"
                     /protein_id="NP_060122.2"
                     /db_xref="CCDS:CCDS42640.1"
                     /db_xref="GeneID:54807"
                     /db_xref="HGNC:HGNC:25949"
                     /translation="MAAAAALRAPAQSSVTFEDVAVNFSLEEWSLLNEAQRCLYRDVM
                     LETLTLISSLGCWHGGEDEAAPSKQSTCIHIYKDQGGHSGERPYECGEYRKLFKNKSC
                     LTEPRRDHKHRNVRTGERPYECSKYGKLFHQKPTLHIHERFHTGQKTYECSECGKSFH
                     QSSSLLQRQTLHTRERPYECIECGKAFAEKSSLINHRKVHSGAKRYECNECGKSFAYT
                     SSLIKHRRIHTGERPYECSECGRSFAENSSLIKHLRVHTGERPYECVECGKSFRRSSS
                     LLQHQRVHTRERPYECSECGKSFSLRSNLIHHQRVHTGERHECGQCGKSFSRKSSLII
                     HLRVHTGERPYECSDCGKSFAENSSLIKHLRVHTGERPYECIDCGKSFRHSSSFRRHQ
                     RVHTGMRPYK"
     exon            204..330
                     /gene="ZNF586"
                     /inference="alignment:Splign:2.1.0"
     exon            331..2196
                     /gene="ZNF586"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2137..2142
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF586"
                     /note="hexamer: AATAAA"
     polyA_site      2157
                     /gene="ZNF586"
                     /note="major polyA site"
     polyA_site      2196
                     /gene="ZNF586"
                     /note="major polyA site"
ORIGIN      
        1 gcctgtcagg tccatccggc gatgctgggt ctggacgagc tcgggaggag tggttgtggc
       61 cattgcacac aggcggatct gaggttcggc gacgccgctg gtcgcgaccc gggacaggac
      121 aacgacagga acaccgccga gcccgcgttc cccccccgcc cagagtcatg gcggcagcag
      181 ccgctctgag ggcgcctgct cagagcagtg tgacctttga agatgtggct gtaaactttt
      241 ccctggagga atggagtctt cttaatgagg ctcagagatg cctgtaccgt gacgtgatgc
      301 tggagacctt gacacttata tcctccctgg gttgttggca tggaggggaa gatgaggcag
      361 caccttctaa gcagagcacg tgtatacata tatacaaaga ccagggaggt catagtggag
      421 aaaggcctta tgagtgtggg gaatatagga aattatttaa gaacaagtcc tgcctcactg
      481 aacccagaag agatcacaaa cacaggaatg ttcgcactgg agaaaggcct tatgagtgca
      541 gcaaatatgg gaaattattt caccaaaagc ctacactcca tattcatgag agatttcata
      601 ctgggcaaaa gacctatgag tgcagtgagt gtggaaaatc atttcaccaa agctcttcac
      661 tcttgcagcg tcagacactt cacactagag aaaggcctta tgagtgtatt gaatgtggga
      721 aagcctttgc tgaaaagtcc agtctcatta accacaggaa agttcactct ggagcaaagc
      781 gttatgaatg caatgaatgt gggaagtcct ttgcttatac atctagtctc attaaacaca
      841 ggaggattca cactggagag aggccttatg agtgcagtga atgtgggaga tcctttgctg
      901 aaaactccag tcttattaaa cacttgagag ttcacacagg agaaaggcct tatgaatgcg
      961 ttgagtgtgg aaaatcattt cgccgaagct cttcactctt gcagcatcag agagttcaca
     1021 ctagagaaag gccttatgaa tgtagtgaat gtgggaaatc ctttagctta aggtccaacc
     1081 tcattcacca tcagcgagtt catactggag aaaggcatga gtgcgggcag tgtgggaaat
     1141 cctttagccg aaaatctagc cttattatac atctgagagt tcacactgga gaaaggcctt
     1201 atgagtgcag tgactgtggg aaatcctttg ctgaaaactc cagccttatt aaacacttga
     1261 gagttcacac tggagaaagg ccatatgaat gcattgattg tggaaaatca tttcgccaca
     1321 gttcttcgtt ccgtcgccat cagagagttc atactggaat gaggccttat aagtgaagca
     1381 aattttggaa attctcttgc ccaggctttt tgctccttca aggccagaga gttcacacca
     1441 gatcaaggtg ttatgagtgt gacaaatggg gaatattctt tagctagaat gctagcttct
     1501 ttacataaaa gagtgctccc actgaagaag tgccttttga gtgcaatgaa tgtgagaaag
     1561 ccttcagccc tctctcattg gttaccacaa tatttacatg aggaaaatac cacagatgtg
     1621 gaggtaatat tattttttct tcaatataac actggaggaa accccttatg aggatgccat
     1681 ctgcctaaat tgaatgtcat acatcaaata gctgcataca ttccaggtat gtgggaactg
     1741 catagtattt ttcgacctgc ccaggtctct tgctagactt ctgtgactta cagttctctt
     1801 ctaaaaagca tttcaccttt accacttggc aggtgcccac agtacatcat tcgcctaact
     1861 catcatgatc cagaagtaac tttgattttg tttcattcaa cagagggatt ttttagtatc
     1921 ctcagcactc attctattct catttctttc tctccaatga gttaggccat gaacctgact
     1981 catttttggc acagaggact cttctgataa cttgaaaaaa tggactacct ttttcaggga
     2041 tcttttggat ctcacagagt tcttaagatg gaattttcca gcctgccagt catgaatctc
     2101 agacagcctg ccacctattg ccctgatttg tgttataata aaggccttgt tgcttaagac
     2161 accttcagtc tttgcaggag ggcatggaag ctccaa
//
