LOCUS       NM_152279               6197 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 585B (ZNF585B), mRNA.
ACCESSION   NM_152279
VERSION     NM_152279.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6197)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS One 7 (12), e51954 (2012)
   PUBMED   23251661
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY147015.1, BX440867.2, BC093625.1 and AC012309.8.
            
            On Nov 23, 2018 this sequence version replaced NM_152279.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660807.262943.1,
                                           SRR1803611.130077.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000532828.7/ ENSP00000433773.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                AY147015.1         16-72
            58-169              BX440867.2         54-165
            170-2613            BC093625.1         25-2468
            2614-6197           AC012309.8         94804-98387         c
FEATURES             Location/Qualifiers
     source          1..6197
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.12"
     gene            1..6197
                     /gene="ZNF585B"
                     /gene_synonym="SZFP41; Zfp27"
                     /note="zinc finger protein 585B"
                     /db_xref="GeneID:92285"
                     /db_xref="HGNC:HGNC:30948"
     exon            1..96
                     /gene="ZNF585B"
                     /gene_synonym="SZFP41; Zfp27"
                     /inference="alignment:Splign:2.1.0"
     exon            97..311
                     /gene="ZNF585B"
                     /gene_synonym="SZFP41; Zfp27"
                     /inference="alignment:Splign:2.1.0"
     CDS             240..2549
                     /gene="ZNF585B"
                     /gene_synonym="SZFP41; Zfp27"
                     /note="zinc finger protein 41-like protein"
                     /codon_start=1
                     /product="zinc finger protein 585B"
                     /protein_id="NP_689492.3"
                     /db_xref="CCDS:CCDS12500.1"
                     /db_xref="GeneID:92285"
                     /db_xref="HGNC:HGNC:30948"
                     /translation="MPASWTSPQKSSALAPEDHGSSYEGSVSFRDVAIDFSREEWRHL
                     DLSQRNLYRDVMLETYSHLLSVGYQVPKPEVVMLEQGKEPWALQGERPRHSCPGEKLW
                     DHNQHRKIIGYKPASSQDQKIYSGEKSYECAEFGKSFTWKSQFKVHLKVPTGEKLYVC
                     IECGRAFVQKPEFITHQKTHMREKPYKCNECGKSFFQVSSLFRHHRIHTGEKLYECSE
                     CGKGFPYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKIHQKIHTGERSYICIECG
                     QAFIQKTQLIAHRRIHSGEKPYECNNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKV
                     FSNNSNLITHEKIQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGRAFT
                     QKSALTVHQRIHTGEKSYICMKCGLAFIRKAHLITHQIIHTGEKPYKCGHCGKLFTSK
                     SQLHVHKRIHTGEKPYVCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSD
                     LITHQRIHTGEKPYECNTCGKAFTQKSNLNIHQKIHTGERQYECHECGKAFNQKSILI
                     VHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVH
                     QPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITHHR
                     IHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFSNRSNLNKHQTTH
                     TGDKPYKCGICGKGFVQKSVFSVHQSSHA"
     exon            312..438
                     /gene="ZNF585B"
                     /gene_synonym="SZFP41; Zfp27"
                     /inference="alignment:Splign:2.1.0"
     exon            439..531
                     /gene="ZNF585B"
                     /gene_synonym="SZFP41; Zfp27"
                     /inference="alignment:Splign:2.1.0"
     exon            532..6197
                     /gene="ZNF585B"
                     /gene_synonym="SZFP41; Zfp27"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2936..2941
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF585B"
                     /gene_synonym="SZFP41; Zfp27"
                     /note="hexamer: AATATA"
     polyA_site      2956
                     /gene="ZNF585B"
                     /gene_synonym="SZFP41; Zfp27"
                     /note="major polyA site"
     regulatory      6179..6184
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF585B"
                     /gene_synonym="SZFP41; Zfp27"
                     /note="hexamer: AATAAA"
     polyA_site      6197
                     /gene="ZNF585B"
                     /gene_synonym="SZFP41; Zfp27"
                     /note="major polyA site"
ORIGIN      
        1 ggaccggaag tggaagtggt ccccgaaggc tatttcgccg ctggcgtcag gactattttc
       61 acgttttaat gccgagaggt ctctgtgacg attttggttc ttgggtgtct ctggggagtc
      121 cctgggccag accttcctcc agactccagc ccacctcttc ggagcagctc tgctgagttc
      181 acagatgacc actaaacttc aggcacccta gacaaaaagg gttgagatcc agtgtggcca
      241 tgccagctag ttggacctca ccccagaaat cctcagccct ggctccagag gatcatggca
      301 gctcctatga gggatcagtg tccttcaggg atgtggctat cgatttcagc agagaggaat
      361 ggcggcacct ggacctttct cagagaaacc tgtaccggga tgtgatgctg gagacctaca
      421 gccacctgct ctcagtaggg tatcaagttc ctaaaccaga ggtggtcatg ttggagcaag
      481 gaaaggaacc atgggcactg cagggtgaga ggccacgtca cagctgccca ggagagaaat
      541 tatgggacca taatcaacat agaaaaatca tcggttataa accagcttcc tctcaagatc
      601 aaaaaattta ttctggggaa aaatcctatg agtgtgctga atttggaaag agcttcacct
      661 ggaagtcaca gttcaaggta catctgaaag ttcctacagg agaaaaactc tatgtatgta
      721 ttgaatgtgg gagggctttt gtacagaagc cagaattcat cacacatcag aaaacccata
      781 tgagagagaa gccctataag tgcaatgaat gtggaaaatc cttttttcaa gtatcgtctc
      841 ttttcaggca tcacagaatt cataccggag aaaaactata tgaatgtagt gaatgtggga
      901 aaggtttccc ttataactca gatctcagta tacatgagaa aattcatact ggagagagac
      961 accatgaatg cactgactgt ggcaaagcgt tcacacaaaa gtccacactc aagattcatc
     1021 agaaaatcca tacaggcgag agatcctaca tctgtattga atgcgggcag gccttcatcc
     1081 agaaaacaca attgattgca caccgaagaa ttcatagtgg agaaaaacca tatgaatgca
     1141 ataactgtgg caaatccttc atttccaagt cacaacttca ggtacatcaa cgtgttcaca
     1201 caagagtgaa gccctatata tgtaccgaat atgggaaggt cttcagcaat aattccaacc
     1261 tcattacaca tgagaagatt caaagtagag agaaatcttc catatgtact gagtgtggga
     1321 aggcctttac ctacaggtca gagttgatta ttcatcagag aattcacact ggagagaaac
     1381 cttatgaatg cagtgactgt gggagagcct tcactcagaa gtcagcactc acagtgcatc
     1441 agagaattca tacaggagaa aaatcgtata tatgcatgaa atgtggactg gccttcatcc
     1501 ggaaggcaca cttgattaca catcaaataa ttcatactgg agagaaacct tataaatgtg
     1561 gtcactgtgg gaaattgttt acttccaagt cacaactcca tgttcataaa cgaattcaca
     1621 caggagaaaa gccctatgta tgcaataaat gtgggaaggc attcaccaac cggtcaaatc
     1681 tcattacaca tcagaaaact catacaggag agaaatctta tatatgttcc aaatgtggaa
     1741 aggccttcac ccagaggtca gacttgatta cacatcagag aatccatact ggggagaagc
     1801 cttatgaatg caatacttgt ggaaaagcct ttactcagaa gtcaaatctt aatatacatc
     1861 agaaaattca cactggagag agacagtatg aatgccacga atgtgggaaa gccttcaacc
     1921 agaaatcaat actcattgtt catcagaaaa ttcatacagg agagaaaccc tatgtatgca
     1981 ctgagtgtgg aagagctttc atccgcaagt caaactttat tactcatcaa agaattcata
     2041 ctggagagaa gccttatgaa tgcagtgact gtgggaagtc ctttacctcc aagtctcagc
     2101 tcctggtgca tcagccagtt cacacaggag agaaacccta tgtgtgtgcc gagtgtggga
     2161 aagcctttag tggcaggtca aatctcagta agcaccagaa aactcatacc ggagaaaagc
     2221 cctacatttg ttctgaatgt gggaagacct ttcgacagaa gtcagagttg attacacatc
     2281 acagaattca tactggagag aaaccttatg agtgcagtga ctgtgggaag tctttcacta
     2341 aaaaatcaca gctccaagtg catcagcgaa ttcacactgg agagaagcct tacgtgtgtg
     2401 ctgagtgtgg gaaggccttt agcaacaggt ccaatttgaa taaacatcag acaacacaca
     2461 ctggagacaa accctacaag tgtggcatct gtgggaaagg cttcgttcag aaatcagtgt
     2521 tcagtgttca tcagagcagc cacgcttgag agaaacagtg tgagaaaacc cccctgaggg
     2581 ttgggtctga ttgtacactg ttgcacgcat gcagcagaaa aatatgtata ttattgtaaa
     2641 tagaaatgac cacatcagaa tgtcacacat ggctgttctg gagagggcct ctgagaaggc
     2701 actgaatgag gcgagggacc cttcctacat tgtcaccatc cccagtaaac cttgggtcat
     2761 tattcatact gacaaggaac cgagtcaatt tggtgaatag gaaaagcctt ctcatgaaaa
     2821 ctacaataga atactgttac caaattcttc ataagaaaga tcatattatg ggaatgataa
     2881 tcctgtttac tgtggattag gtatagtgcc aacagtttga atggtaagac aacataatat
     2941 atatgatagt gatgaatcct tctgtgagtt gtttgttcca gaacacactg tctagtagaa
     3001 ttgtgggtat tttcttcttt tgaatcgaac acagttgtgc atatccaatt ccccattgag
     3061 tatttctatc aagcaagaga tactgcaata agacaaactc cctgtgtatt cagacacaga
     3121 cctcagagcg tatgttgagt ccccattgtc atagaaaaag acttacagtc cccttcatta
     3181 tctgccagga ctctctctga gccccacagg ttctcagcac attgtgtttg acacccagca
     3241 cagtgttttt tctttttctt tctttctttc tctttctttc tttctttctt tctttctttc
     3301 tttctttctt tctttctttc tttctttctt tccttctttc tttctttttc tttctttctc
     3361 tttctttctt tctttctttc tttctttctt tctttctttc tttctttctt tctttctttt
     3421 tttgagacag agtcttgctc tgtcgggcaa gctagagtgc agtggcgcta tcttggctca
     3481 ctgcaacctc cgtctcccgg gctcaagcaa ttctcctgcc tcagcctcct gagtagctgg
     3541 gattgcgtgt gccaccacgc ccagctaatt tttgtatgtt tagtagaaac gggggtttca
     3601 ccatgctggc caggctggtc tcgaactcct gacctcatga tccgcccgcc tcggcctccc
     3661 aaagtcctgg gattacggac gtgagccact gcgcccggcc cagcacagtg ttttgtacac
     3721 tcccaccacc ctcaagaaag cctttgaggt taggattttc aggtcatctg ggagaactta
     3781 aattcttcct tctgctatta caattcttct cactcagttg cctgcctctt tttttttttt
     3841 aatttacttg tgactgagtt gaagcccagc attttacttt ccttaatgat ctgactttca
     3901 taagttgata agtcatgaaa tcattatctt acattatatg agatatgaga taaatcataa
     3961 atcatatgaa attgataact catatgaaaa ccaaccccac catatgttca ctgtctactt
     4021 gtgtccatct tcgtcccacg caccccacaa ggaccttccc cgccatgtgc ctcaaacatc
     4081 agttcctgac tcagggcctt tgtatttgca gtgcccgttg caaagagcac aattctttat
     4141 tttatctgtg gcttgtccgt catgtctttt tttccatgac acctccacac aggccttccc
     4201 tgcctgcctg gtttaaaatt ccagcccctt acccttcctc ctttattctt ctccctagca
     4261 atttccacca tgctgcctgg tgtattttcc tcatttctct gtggcttcta cactagaaaa
     4321 tatttccctt ttgttcacca ctatgagtct agacccatga ctgccataca gcaggcattc
     4381 cataaatgca cctgtggaga gttgacccat gcttgttgcg tgacttctgt ctgatttttt
     4441 tctgtgttgc agcataagaa gcgctaatag ggagaaccaa cttggctaaa acacaccagg
     4501 ctttttcacc tctagtctgt acctgggctg tatcccttct caaccctaaa gctaaaaagt
     4561 cattgtgaac cttttggtct gatgctaaag aagggaaaac aggtacagga aatcccatgt
     4621 ggatgcttgc ttccaggatt tcctgccatg attccagaat cccacagctc caacatgatt
     4681 gcaaaagact ccctgctcat ttttcctcag catgcacagc gctgtcctgt ctcagttgca
     4741 actcgacaga gccgcattta ctccagaacc caatccacac acctgctcat cctgccccga
     4801 gaggagtgcc tgaagccaat agcagggaac tagagcagac ttgggtggat cttcattgga
     4861 tattaggtat cttgccctag ataggcagca gtggccttac agatgctgac agatgatctg
     4921 attagatgca cagttgctgg gtggcgtctg gggccagtct attggcagtt ctgggagtgg
     4981 gaactatttg ggctctgcaa agatggtttc acctttaaga agggcagtat ggggaggtga
     5041 agatggggcc caaaggatag aacatagtca aagaagcagg gccacaatgc ccctttaatt
     5101 cccaagccct agttgggcag tgcttggtga cacatcccat tacctcacct tagatcaatg
     5161 tctactgagc catcattagc tctgcttcct cacttcttca cagtatctga tggcccatca
     5221 catgctgctc aacatcttag accaatgtct gctcacccat tacctccctt cacctcatcc
     5281 agcactgtat ctgaagcttc actattcttc cttcagtttt ggatattttg tgatacaaca
     5341 ttatccccaa cttaggacaa tgtcagctga ctctcaggag ggtgcctgga gatcacctct
     5401 tccttcctaa cataccctag aacaaggtct ggtccccttc attattccca ttttacctta
     5461 ctcctaagtg tatcactcct catgaattcc aggaaatatg gaggaaaaca catttcactg
     5521 tacatgactt tcaataattt ctcctttata tttattgtaa cgtgatattt tagtgctgac
     5581 atatatatgt atatgtatgc ccatttatat aaaagactag tttttagaga aattttaggt
     5641 tcacagcaaa atggggcaga aggtacagag atttcccata tatcccctac cctcacatat
     5701 acacagcctc ccccatcatc aacatccccc ttcagagtgg tacatttgtt acaattgatg
     5761 aaactacatt gacactatcg gccaaagtcc atggtttaat tagggttcag tcttgatgtg
     5821 cattctgtgg gttgagacaa atgaataatg acatgtatgc attattacag aaggataaag
     5881 agccgtttca ctgtcccaat aatcctctgt gtttcgccta ctcctctaaa ctcctggcta
     5941 ttttcttttg tctccataat tttgcctctg aaccataaag tatgcagcct tttcagattg
     6001 atttgtttca cttagtaatg tggatttaag tttcttccat gtcttttcgt agcttgctag
     6061 ctcttttttt tttttttttc tcattgaata atatgctatt gtctggaagt accatgactt
     6121 atttatccat tcacctactg aaggacacct taattgcttc caagttttgt tgattatgaa
     6181 taaagatgct ataaaca
//
