LOCUS       NM_152478               4916 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 583 (ZNF583), transcript variant
            1, mRNA.
ACCESSION   NM_152478
VERSION     NM_152478.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4916)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 4916)
  AUTHORS   Kimura,K., Wakamatsu,A., Suzuki,Y., Ota,T., Nishikawa,T.,
            Yamashita,R., Yamamoto,J., Sekine,M., Tsuritani,K., Wakaguri,H.,
            Ishii,S., Sugiyama,T., Saito,K., Isono,Y., Irie,R., Kushida,N.,
            Yoneyama,T., Otsuka,R., Kanda,K., Yokoi,T., Kondo,H., Wagatsuma,M.,
            Murakawa,K., Ishida,S., Ishibashi,T., Takahashi-Fujii,A.,
            Tanase,T., Nagai,K., Kikuchi,H., Nakai,K., Isogai,T. and Sugano,S.
  TITLE     Diversification of transcriptional modulation: large-scale
            identification and characterization of putative alternative
            promoters of human genes
  JOURNAL   Genome Res 16 (1), 55-65 (2006)
   PUBMED   16344560
REFERENCE   3  (bases 1 to 4916)
  AUTHORS   Gerhard,D.S., Wagner,L., Feingold,E.A., Shenmen,C.M., Grouse,L.H.,
            Schuler,G., Klein,S.L., Old,S., Rasooly,R., Good,P., Guyer,M.,
            Peck,A.M., Derge,J.G., Lipman,D., Collins,F.S., Jang,W., Sherry,S.,
            Feolo,M., Misquitta,L., Lee,E., Rotmistrovsky,K., Greenhut,S.F.,
            Schaefer,C.F., Buetow,K., Bonner,T.I., Haussler,D., Kent,J.,
            Kiekhaus,M., Furey,T., Brent,M., Prange,C., Schreiber,K.,
            Shapiro,N., Bhat,N.K., Hopkins,R.F., Hsie,F., Driscoll,T.,
            Soares,M.B., Casavant,T.L., Scheetz,T.E., Brown-stein,M.J.,
            Usdin,T.B., Toshiyuki,S., Carninci,P., Piao,Y., Dudekula,D.B.,
            Ko,M.S., Kawakami,K., Suzuki,Y., Sugano,S., Gruber,C.E.,
            Smith,M.R., Simmons,B., Moore,T., Waterman,R., Johnson,S.L.,
            Ruan,Y., Wei,C.L., Mathavan,S., Gunaratne,P.H., Wu,J., Garcia,A.M.,
            Hulyk,S.W., Fuh,E., Yuan,Y., Sneed,A., Kowis,C., Hodgson,A.,
            Muzny,D.M., McPherson,J., Gibbs,R.A., Fahey,J., Helton,E.,
            Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M.,
            Madari,A., Young,A.C., Wetherby,K.D., Granite,S.J., Kwong,P.N.,
            Brinkley,C.P., Pearson,R.L., Bouffard,G.G., Blakesly,R.W.,
            Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J.,
            Myers,R.M., Butterfield,Y.S., Griffith,M., Griffith,O.L.,
            Krzywinski,M.I., Liao,N., Morin,R., Palmquist,D., Petrescu,A.S.,
            Skalska,U., Smailus,D.E., Stott,J.M., Schnerch,A., Schein,J.E.,
            Jones,S.J., Holt,R.A., Baross,A., Marra,M.A., Clifton,S.,
            Makowski,K.A., Bosak,S. and Malek,J.
  CONSRTM   MGC Project Team
  TITLE     The status, quality, and expansion of the NIH full-length cDNA
            project: the Mammalian Gene Collection (MGC)
  JOURNAL   Genome Res 14 (10B), 2121-2127 (2004)
   PUBMED   15489334
  REMARK    Erratum:[Genome Res. 2006 Jun;16(6):804. Morrin, Ryan [corrected to
            Morin, Ryan]]
REFERENCE   4  (bases 1 to 4916)
  AUTHORS   Suzuki,Y., Yamashita,R., Shirota,M., Sakakibara,Y., Chiba,J.,
            Mizushima-Sugano,J., Nakai,K. and Sugano,S.
  TITLE     Sequence comparison of human and mouse genes reveals a homologous
            block structure in the promoter regions
  JOURNAL   Genome Res 14 (9), 1711-1718 (2004)
   PUBMED   15342556
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA785623.1, BC111772.1, AK055592.1 and AC006116.1.
            
            On May 17, 2019 this sequence version replaced NM_152478.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Variants 1, 2 and 3 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.167651.1,
                                           SRR1660809.196963.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000333201.13/ ENSP00000388502.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-111               DA785623.1         8-118
            112-2549            BC111772.1         1-2438
            2550-2583           AK055592.1         2533-2566
            2584-4916           AC006116.1         149370-151702
FEATURES             Location/Qualifiers
     source          1..4916
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..4916
                     /gene="ZNF583"
                     /note="zinc finger protein 583"
                     /db_xref="GeneID:147949"
                     /db_xref="HGNC:HGNC:26427"
     exon            1..121
                     /gene="ZNF583"
                     /inference="alignment:Splign:2.1.0"
     exon            122..219
                     /gene="ZNF583"
                     /inference="alignment:Splign:2.1.0"
     CDS             211..1920
                     /gene="ZNF583"
                     /note="zinc finger protein L3-5"
                     /codon_start=1
                     /product="zinc finger protein 583"
                     /protein_id="NP_689691.2"
                     /db_xref="CCDS:CCDS12943.1"
                     /db_xref="GeneID:147949"
                     /db_xref="HGNC:HGNC:26427"
                     /translation="MSKDLVTFGDVAVNFSQEEWEWLNPAQRNLYRKVMLENYRSLVS
                     LGVSVSKPDVISLLEQGKEPWMVKKEGTRGPCPDWEYVFKNSEFSSKQETYEESSKVV
                     TVGARHLSYSLDYPSLREDCQSEDWYKNQLGSQEVHLSQLIITHKEILPEVQNKEYNK
                     SWQTFHQDTIFDIQQSFPTKEKAHKHEPQKKSYRKKSVEMKHRKVYVEKKLLKCNDCE
                     KVFNQSSSLTLHQRIHTGEKPYACVECGKTFSQSANLAQHKRIHTGEKPYECKECRKA
                     FSQNAHLAQHQRVHTGEKPYQCKECKKAFSQIAHLTQHQRVHTGERPFECIECGKAFS
                     NGSFLAQHQRIHTGEKPYVCNVCGKAFSHRGYLIVHQRIHTGERPYECKECRKAFSQY
                     AHLAQHQRVHTGEKPYECKVCRKAFSQIAYLDQHQRVHTGEKPYECIECGKAFSNSSS
                     LAQHQRSHTGEKPYMCKECRKTFSQNAGLAQHQRIHTGEKPYECNVCGKAFSYSGSLT
                     LHQRIHTGERPYECKDCRKSFRQRAHLAHHERIHTMESFLTLSSPSPSTSNQLPRPVG
                     FIS"
     exon            220..346
                     /gene="ZNF583"
                     /inference="alignment:Splign:2.1.0"
     exon            347..442
                     /gene="ZNF583"
                     /inference="alignment:Splign:2.1.0"
     exon            443..4916
                     /gene="ZNF583"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2114..2119
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF583"
                     /note="hexamer: ATTAAA"
     polyA_site      2133
                     /gene="ZNF583"
                     /note="major polyA site"
     regulatory      3183..3188
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF583"
                     /note="hexamer: AATAAA"
     polyA_site      3214
                     /gene="ZNF583"
                     /note="major polyA site"
     regulatory      3375..3380
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF583"
                     /note="hexamer: AATACA"
     polyA_site      3397
                     /gene="ZNF583"
     regulatory      4284..4289
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF583"
                     /note="hexamer: AATAAA"
     polyA_site      4306
                     /gene="ZNF583"
     regulatory      4849..4854
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF583"
                     /note="hexamer: AATAAA"
     polyA_site      4877
                     /gene="ZNF583"
     regulatory      4894..4899
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF583"
                     /note="hexamer: AATATA"
     polyA_site      4916
                     /gene="ZNF583"
ORIGIN      
        1 agggctgcgg cgcctttgtg agcgcggccg ccggccagga tcgagccctg gcccgggccc
       61 tggcccagcc ccggcctcca aggaccgcgc cgaaggaggt gcccactgga gggaggaggc
      121 gctcgacttt ctcaggatac tgtccctctc ccacagagga gctgaaggag taggacagaa
      181 gaactgtcaa attctggaat ccttaaagcc atgtccaagg atttggtgac atttggggat
      241 gtggctgtaa atttctctca agaggaatgg gaatggctga accctgctca gaggaatttg
      301 tacaggaaag tgatgttgga gaactacagg agcttggtat cattgggagt ttctgtttct
      361 aagccagatg tgatctcatt attggagcaa ggaaaagagc cctggatggt gaagaaggag
      421 ggaacaagag gcccatgccc tgattgggag tatgtattta aaaacagtga attttcatca
      481 aagcaagaga catatgaaga atcatccaaa gttgtgacag tgggagcaag acatcttagt
      541 tatagccttg actatcccag tttgagagaa gactgtcaaa gtgaggactg gtataagaac
      601 cagctgggaa gtcaagaggt acatcttagt caattaatca tcactcataa agaaatcctt
      661 ccagaagttc aaaataaaga atataacaaa tcttggcaaa cattccacca ggatacaatc
      721 tttgatatac aacagagttt tcccaccaaa gaaaaagcac ataagcatga accacaaaag
      781 aaaagttacc gaaaaaaatc tgttgaaatg aaacatagga aagtctatgt agaaaagaaa
      841 cttttgaaat gtaatgattg tgagaaagtc ttcaaccaga gctcatccct tactcttcat
      901 cagagaattc atactggaga gaaaccctat gcatgtgttg aatgtgggaa aacgttcagc
      961 cagagtgcaa acttggcgca acataagaga atacatactg gagagaaacc ctatgaatgt
     1021 aaagaatgta ggaaagcctt cagccagaat gcacacctgg cccaacatca gagagttcat
     1081 actggagaga aaccttatca gtgtaaagaa tgtaaaaaag ccttcagcca gattgcacac
     1141 ctgactcagc atcagagagt tcatactgga gagagacctt tcgaatgtat tgaatgtgga
     1201 aaggccttta gtaatggttc atttcttgct cagcatcaga gaattcatac aggagagaaa
     1261 ccttatgtgt gtaatgtgtg tgggaaagcc tttagccatc gtggatacct aattgtacat
     1321 cagagaattc atactggaga gagaccctac gaatgtaagg aatgtaggaa agccttcagc
     1381 cagtatgcac accttgctca acatcagaga gttcatactg gagaaaaacc ttatgaatgt
     1441 aaagtatgta ggaaagcctt cagccaaatt gcataccttg atcaacatca gagggttcat
     1501 actggagaga aaccctatga atgtattgaa tgtgggaagg cctttagcaa tagttcatca
     1561 cttgcacaac atcagagaag tcatactgga gaaaaaccct atatgtgtaa ggaatgtagg
     1621 aaaacattta gccagaatgc aggccttgct caacatcaga gaattcatac tggagagaaa
     1681 ccttatgaat gtaatgtttg tgggaaagca tttagctata gtggatctct tactctacat
     1741 cagagaattc atactggaga aagaccctat gaatgtaaag attgcaggaa atctttcagg
     1801 cagcgtgcac atcttgctca tcatgagaga attcatacta tggagtcatt cttgactctt
     1861 tcctctccct caccctccac atcaaatcag ttgccaagac ctgtaggttt catctcctga
     1921 atatttctgg aatccacctc ttgaatccat ttccatccca tcatccttgt ccaatgcaca
     1981 ttaatatatt tgacatggga tactcgagta gctttctaat tggtctcctt gtactcacca
     2041 ttgtctctgt cagatgtcca cattgcaacc aaatttgtat ttttaaaaat atgtttaatc
     2101 tcatttctcc ctcattaaaa tccctcagtg gcatcccatg gtttttaagt taaagcacac
     2161 attcttcaaa atagcctaaa aacctagcct ctaacacctt gttccaggtt accttccaaa
     2221 gtttctatct tgtgtcacta tccatctcat tctctgaata cttatccagg attaagatac
     2281 atattccagg atcaaaaaga cctgggttcc aatctttgca cttccatttc ctgccctcta
     2341 atttgggggc agcagtttgt gctttgtaag cttcagtctt atttatagtg tgggaataat
     2401 aatggttcta cctcagaagt taatagaaga atgaaataat gcatgtaaat tgctcagcag
     2461 cgtgcctagc ataaagtaat tactcaaacc ataatgtaaa gtaaaaagat aaccatacta
     2521 tacatagaaa gccaatcatc tcagccatga ttatctcaga aataaaaaga gatgcagcag
     2581 ctcaggactg agagattgtg aagttttttt ttttttagga atggtaggca tttttctaaa
     2641 agtaggtgag gagggtatct aacagtagga tttacattag agtccatgat atagggtaag
     2701 atggtggctt gtatcagcat tcactggata tttaacagtt ctaagatgct aatgtcttat
     2761 tttaaaagtc tttttttttg agatggagtc ttgctctgtt gctcaggctt gagtgcagta
     2821 gtgcaatctt ggctcactgc aacctccgcc tcctgtgttc aagtgattct cctgcctcag
     2881 cctcctgagt agctgggatt acaggcctgc accaccacgc ccagctaatt tttgtatttt
     2941 tagtagagag agggttttga catgtcggcc aggcttttct ctaactcctg acgtccggtg
     3001 atccgcctgc cttggcctcc caaagtgctg ggattacatg cgtgagctac cgtgcctggc
     3061 ctaaaaagtc atttttaata agacagttta ctgagatgta ttcatcattt acatgtaaac
     3121 aaaggcaaaa tcgaaattaa aaagaaatct tgaaacaagt cagtaaccaa tgatgagtag
     3181 aaaataaagt ataagtttga acccctgttc taaatctggg tgaatgaatt atatcaaatc
     3241 tatgtcattt aaaataataa aggttgttaa attactaaaa tttcaaaact agtgaagaaa
     3301 agaaaccaaa actgtaggtc agttctcata aactggccca caaacatgtt tgattctgta
     3361 tgcattaagt ttaaaataca tatgaatacc ttcagcagac catgtgtttt ccctttctcc
     3421 aacattcaaa ccactccctg attctttaca tctgacctct tttaatatta cttcctgacc
     3481 ccagaattct tttggcatat aatcaatgca gtgatcaatt cacatgtgac tatagataca
     3541 aacagaatga cgaaagttta atggaggatg aaaaagaaga caaataaata ttttatcctt
     3601 tatatggtaa gacagattca ctatcatact gatgtcagta gcccatgaat taatttacag
     3661 attctaccta acaaaattct aataaatttt gtaaggtttt aacatgtatg tgtgaacata
     3721 catattcatg ctgttacaca tataaagaaa attataacaa aagtgaccta taccatcagt
     3781 ggtttaacag ttttggaaaa atttatcgtg ctctatacaa caattcattc catatgtgaa
     3841 agttactttc aagtgcttta tctaaatgtg gaacaaacag tgattagagg agtctgtgac
     3901 acactctaat catggaatga gactggcctt cctaaacatg agattcagaa gcctccccac
     3961 ctcctgtcaa caagtcatag atttgactgt ataagaactt tataaagctt ttatatgatc
     4021 aaagatagta aaagatacaa tattttttaa acctaagaat gggagaaaat tattgcagca
     4081 catataaact atggaattca tatccttaac ataaaattgc tcataaaaat cccttaggaa
     4141 atgacgcttt tctccagctc atagtcaaag gatatgaaga ggcaacaggt gaccaataaa
     4201 tatgtggtaa gtactaaatc tccctaggat cagaagaaat acagtttagg ccaatgaaat
     4261 actatttttt tcaatatcag attaataaaa ctgcattgaa agcatacaaa aagagatact
     4321 atgcactaat ttaaaagagc atgagtttgt acaaactctg gtaggcaatt tgtcaacttc
     4381 agaattttaa ttgggaaaag tagaatttta ttttgaagtt caaaaactcg gcacacaatg
     4441 tctttccctc cagattctat tatacacata gaacaatgta aatgattctt aaaaaaaaaa
     4501 aaaaggtgag gcttttgagt ggatgaaata attttgtaaa aggcaaaaca gggaagagtg
     4561 ttcatgaatt gtagcagaag atgctgcatg ttatatgcga atgaccgaag ggttttaaaa
     4621 atggaatcta gtctgcccaa aggatcccta gagaagttca ggcttggagt tggcttatgt
     4681 acaggctgtg gcttctaaga agacatgatg aaaagcctct tgaagccttt gtatgtgaaa
     4741 gttatgtcag tagcccttgc caaaagcctc ctcactctcc cctctcttgt ataagtaaat
     4801 tgaatgggat ccttatttca caccattaac aagtataagt tctaactgaa taaaaatcta
     4861 aatgtaaatt actaaagcaa aagtattaga aaaaatatag tgggatatgt taacga
//
