LOCUS       NM_152600               2922 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens zinc finger protein 579 (ZNF579), mRNA.
ACCESSION   NM_152600
VERSION     NM_152600.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2922)
  AUTHORS   Zhou,Y., Liu,Y., Gupta,S., Paramo,M.I., Hou,Y., Mao,C., Luo,Y.,
            Judd,J., Wierbowski,S., Bertolotti,M., Nerkar,M., Jehi,L.,
            Drayman,N., Nicolaescu,V., Gula,H., Tay,S., Randall,G., Wang,P.,
            Lis,J.T., Feschotte,C., Erzurum,S.C., Cheng,F. and Yu,H.
  TITLE     A comprehensive SARS-CoV-2-human protein-protein interactome
            reveals COVID-19 pathobiology and potential host therapeutic
            targets
  JOURNAL   Nat Biotechnol 41 (1), 128-139 (2023)
   PUBMED   36217030
REFERENCE   2  (bases 1 to 2922)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 2922)
  AUTHORS   Schlag,K., Steinhilber,D., Karas,M. and Sorg,B.L.
  TITLE     Analysis of proximal ALOX5 promoter binding proteins by
            quantitative proteomics
  JOURNAL   FEBS J 287 (20), 4481-4499 (2020)
   PUBMED   32096311
REFERENCE   4  (bases 1 to 2922)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   5  (bases 1 to 2922)
  AUTHORS   Teumer,A., Holtfreter,B., Volker,U., Petersmann,A., Nauck,M.,
            Biffar,R., Volzke,H., Kroemer,H.K., Meisel,P., Homuth,G. and
            Kocher,T.
  TITLE     Genome-wide association study of chronic periodontitis in a general
            German population
  JOURNAL   J Clin Periodontol 40 (11), 977-985 (2013)
   PUBMED   24024966
REFERENCE   6  (bases 1 to 2922)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   7  (bases 1 to 2922)
  AUTHORS   Beausoleil,S.A., Villen,J., Gerber,S.A., Rush,J. and Gygi,S.P.
  TITLE     A probability-based approach for high-throughput protein
            phosphorylation analysis and site localization
  JOURNAL   Nat Biotechnol 24 (10), 1285-1292 (2006)
   PUBMED   16964243
REFERENCE   8  (bases 1 to 2922)
  AUTHORS   Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
            Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
  TITLE     Large-scale characterization of HeLa cell nuclear phosphoproteins
  JOURNAL   Proc Natl Acad Sci U S A 101 (33), 12130-12135 (2004)
   PUBMED   15302935
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008735.9, CN340494.1, CX781546.1, AK092772.1 and AW003562.1.
            
            On Nov 23, 2018 this sequence version replaced NM_152600.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK092772.1, SRR1163655.402716.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1970526
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000325421.7/ ENSP00000320188.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC008735.9         95499-95501
            4-440               CN340494.1         3-439
            441-829             CX781546.1         231-619
            830-2163            AK092772.1         803-2136
            2164-2171           AW003562.1         6-13                c
            2172-2922           AC008735.9         98823-99573
FEATURES             Location/Qualifiers
     source          1..2922
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.42"
     gene            1..2922
                     /gene="ZNF579"
                     /note="zinc finger protein 579"
                     /db_xref="GeneID:163033"
                     /db_xref="HGNC:HGNC:26646"
     exon            1..54
                     /gene="ZNF579"
                     /inference="alignment:Splign:2.1.0"
     exon            55..2922
                     /gene="ZNF579"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..1745
                     /gene="ZNF579"
                     /codon_start=1
                     /product="zinc finger protein 579"
                     /protein_id="NP_689813.2"
                     /db_xref="CCDS:CCDS12927.1"
                     /db_xref="GeneID:163033"
                     /db_xref="HGNC:HGNC:26646"
                     /translation="MDPQPPPPAQGSPPHRGRGRGRGRGRGRGRGRGRGGAGAPRAPL
                     PCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRHLRGHGPQPPLRC
                     AACPRTFPEPAQLRRHLAQEHAGGEVELAIERVAKETAEPSWGPQDEGSEPPTTAAAG
                     ATEEEAVAAWPETWPAGEPSTLAAPTSAAEPRESESEEAEAGAAELRAELALAAGRQE
                     EKQVLLQADWTLLCLRCREAFATKGELKAHPCLRPEGEQEGEGGPPPRPKRHQCSICL
                     KAFARPWSLSRHRLVHSTDRPFVCPDCGLAFRLASYLRQHRRVHGPLSLLAPLPAAGK
                     KDDKASGARNSAKGPEGGEGAECGGASEGGEGQNGGDAAPARPPAGEPRFWCPECGKG
                     FRRRAHLRQHGVTHSGARPFQCVRCQREFKRLADLARHAQVHAGGPAPHPCPRCPRRF
                     SRAYSLLRHQRCHRAELERAAALQALQAQAPTSPPPPPPPLKAEQEEEGLPLPLANIK
                     EEPPSPGTPPQSPPAPPVFLSASCFDSQDHSAFEMEEEEVDSKAHLRGLGGLAS"
     regulatory      2146..2151
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF579"
                     /note="hexamer: AATAAA"
     polyA_site      2171
                     /gene="ZNF579"
                     /note="major polyA site"
     regulatory      2897..2902
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF579"
                     /note="hexamer: AATAAA"
     polyA_site      2922
                     /gene="ZNF579"
ORIGIN      
        1 accgtccgcg tttggccggc cgtggggaag gaagaaagga gccaaggagg cgaggcatgg
       61 atccgcagcc tcctccaccc gcccagggca gcccacctca ccgtggccga ggccggggcc
      121 gtggccgagg ccgtggtcgg ggccgtggcc gtggcagggg gggcgctgga gcccctaggg
      181 cgcccctgcc ctgccccacc tgcggccgcc tcttccgttt cccctactac ctctcccggc
      241 accggctgag ccactcgggg ctccggcccc acgcctgccc gctgtgcccc aaggccttcc
      301 gccggccggc ccacctttcc cgccacctgc gcggccacgg gccccagccc ccgctgcgct
      361 gcgccgcctg cccccgcacc ttcccagaac cggcccagct caggcgccac ctggctcagg
      421 agcacgcggg cggcgaggtc gagctggcca tcgagagggt ggccaaggag acggccgaac
      481 ccagctgggg cccgcaggac gagggctcgg agccgcccac caccgctgca gcaggggcca
      541 cggaggagga ggcggtcgca gcgtggcctg agacgtggcc tgcgggggag ccttccacgc
      601 tggctgcgcc caccagcgcc gcggagcccc gggagtcgga gtcggaggag gccgaggccg
      661 gggcagcaga gctgagggcc gagctggcgc tggcggccgg gcggcaggag gagaaacagg
      721 tcctgctcca ggcagactgg acgctgctgt gtctgcgctg ccgcgaagcc ttcgccacca
      781 agggcgagct caaggcgcac ccgtgtctgc gccccgaggg cgaacaggaa ggggaagggg
      841 ggcccccgcc acgccccaag cgacaccagt gctccatctg cctcaaggcc ttcgccaggc
      901 cctggtccct gtcgcgccac cggctggtcc actccaccga ccgccctttc gtgtgcccag
      961 actgcggcct ggccttccgc ctcgcctcct acctccgcca gcaccgccgc gtccacggcc
     1021 ccctcagcct gctggccccg ctgcccgcgg cgggcaagaa ggacgacaag gcctcgggtg
     1081 cacggaactc agccaagggg ccggaggggg gcgagggggc ggagtgcggg ggtgcctcgg
     1141 aagggggaga agggcagaac ggaggcgacg ccgccccggc tcggcccccc gccggggagc
     1201 cccgcttctg gtgcccagag tgcggcaaag gtttcaggcg ccgggcgcac ctgcggcagc
     1261 acggggtgac ccactcggga gcgcgcccct tccagtgcgt gcgctgccag cgggagttca
     1321 agcgcctggc cgacctggcg cgccacgcac aggtgcacgc ggggggccca gccccgcacc
     1381 cgtgcccccg ctgcccgcgc cgcttctcgc gcgcctacag cctcctgcgc caccagcgct
     1441 gccaccgcgc agagctggag agggccgccg cgctgcaggc actgcaggcc caggccccga
     1501 cgtcgccgcc accgcccccg ccgcccctga aggccgagca ggaggaagaa gggctcccgc
     1561 tgcccctcgc aaacattaag gaagagccgc cctctccggg gaccccaccc cagtccccgc
     1621 cggctccccc tgtcttcctc agcgcctcct gtttcgacag ccaagaccac tcagccttcg
     1681 agatggagga ggaagaggta gacagcaagg ctcacctgcg cgggctgggg ggcctggcct
     1741 cctgaccttc gccgccctgc cctccgccgc tccgcctgag ctccccggtt tgcagaatgg
     1801 aggagggaag ttgaaggagc cacctcctct gtctacccac ccgtcccctt cacgcccttg
     1861 acactaagga gtggggggcc ctggactgcc ccttcctccc ccatcgcccg cccccagaac
     1921 ccctgatgct ggttaggaac cgctcacccc aacatgtgtc ttaaggcagg acgacttgga
     1981 aaaaaaggcg gcggacagtt ggccagaggg atggagactg gtggggacgc ccccgcctcc
     2041 ctgtcccccg tttcacacac tggacaccat cacctctttg gaactgccag accctggggg
     2101 tccccagtga gcaaaggtct gtccttgtcc ctttgtctgt ctgtgaataa atgtgagttc
     2161 gtgaaatcca agagagcgag gtgttctgtg gaggtggggc aggctggggg cgctggggcg
     2221 agtcaggatt tgtccagcca actctgaact tgggttcaga gcaggaagga cacagatgca
     2281 tcagaaaata tgtggccctc aaccaagcaa gaagccggtg aaggctgggt tgagaagaaa
     2341 caggaatgtg agaagataga tcatcgtcac cgctgccctg tggaagctcc gcgcgattat
     2401 cctcaccact gccctgtgga agctccgcgc cttactcagt caatctctac cacaccctta
     2461 ctctgtgtca gcggtggtac taggcactga ggaggagtcc aataccttcc tctgaaagag
     2521 ctggaattct agccctgcat tgtccaacat aacttttttt ttttctcaga aaagtttcca
     2581 taatctttct tccctcactc tgttgcccaa gctgcagtgc cgtggtgcag tcatagctca
     2641 ctgcagtctc aaactcccag acccaagcaa tcctcttagc ctctcaagga gctaggacta
     2701 caggtgcatg ccaccacacc cagctgattg tttcatttct tgcagagacg gagtcttgct
     2761 atcttgccca gtctgggaga actttttgtg atgatgggat attctacatc ttcactgtcc
     2821 aatatgatat ccagcagaca cacgtggcta tttccgttta aatttagaat atggaaatgt
     2881 aaagacatta agatgaaata aatgtaaaag ttcggttcct ca
//
