LOCUS       NM_152412               3278 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 572 (ZNF572), mRNA.
ACCESSION   NM_152412
VERSION     NM_152412.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3278)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 3278)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 3278)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3278)
  AUTHORS   Simpson,J.C., Wellenreuther,R., Poustka,A., Pepperkok,R. and
            Wiemann,S.
  TITLE     Systematic subcellular localization of novel proteins identified by
            large-scale cDNA sequencing
  JOURNAL   EMBO Rep 1 (3), 287-292 (2000)
   PUBMED   11256614
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC009908.13, DB093007.1, BC130517.1 and AK095321.1.
            
            On Nov 22, 2018 this sequence version replaced NM_152412.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX537876.1, AK095321.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000319286.6/ ENSP00000319305.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 AC009908.13        66123-66124
            3-30                DB093007.1         1-28
            31-1907             BC130517.1         8-1884
            1908-2873           AK095321.1         1893-2858
            2874-3278           AC009908.13        71813-72217
FEATURES             Location/Qualifiers
     source          1..3278
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.13"
     gene            1..3278
                     /gene="ZNF572"
                     /note="zinc finger protein 572"
                     /db_xref="GeneID:137209"
                     /db_xref="HGNC:HGNC:26758"
     exon            1..122
                     /gene="ZNF572"
                     /inference="alignment:Splign:2.1.0"
     exon            123..236
                     /gene="ZNF572"
                     /inference="alignment:Splign:2.1.0"
     CDS             158..1747
                     /gene="ZNF572"
                     /codon_start=1
                     /product="zinc finger protein 572"
                     /protein_id="NP_689625.2"
                     /db_xref="CCDS:CCDS6354.1"
                     /db_xref="GeneID:137209"
                     /db_xref="HGNC:HGNC:26758"
                     /translation="MEQEKKLLVSDSNSFMERESLKSPFTGDTSMNNLETVHHNNSKA
                     DKLKEKPSEWSKRHRPQHYKHEDAKEMPLTWVQDEIWCHDSYESDGKSENWGNFIAKE
                     EEKPNHQEWDSGEHTNACVQQNSSFVDRPYKCSECWKSFSNSSHLRTHQRTHSGEKPY
                     KCSECAKCFCNSSHLIQHLRMHTGEKPYQCGECGKSFSNTSHLIIHERTHTGEKPYKC
                     PECGKRFSSSSHLIQHHRSHTGEKPYECSVCGKGFSHSYVLIEHQRTHTGEKPYKCPD
                     CGKSFSQSSSLIRHQRTHTGEKPYKCLECEKSFGCNSTLIKHQRIHTGEKPYQCPECG
                     KNFSRSSNLITHQKMHTGEKSYESSEYEESLGQNCNVIEECRIQLGEKPYRCCECGKS
                     FGLSSHLIRHQRTHTGEKPYRCSECWKTFSQSSTLVIHQRTHTGEKPYKCPDCGESFS
                     QSFNLIRHRRTHIGEKPYKCTSCEKCFSRSAYLSQHRKIHVEKPFESPDVGDFPHEWT
                     WKNCSGEMPFISSFSVSNSSS"
     exon            237..3278
                     /gene="ZNF572"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3254..3259
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF572"
                     /note="hexamer: AATAAA"
     polyA_site      3278
                     /gene="ZNF572"
                     /note="major polyA site"
ORIGIN      
        1 ctgtttctgc cttccgggtt tgagagttta ggaccctggg ttggtggggt cagagggaga
       61 gggggtacct tcctcccgga ccgctggggg tgcagggcgc cttgggtgta gcacccagaa
      121 caggtttctg atctctaact tggctgtgat cattgtgatg gagcaagaaa aaaaactgtt
      181 ggtctcagat tctaacagct ttatggagag ggagagtttg aaaagccctt tcacaggaga
      241 tacaagtatg aataatttgg aaactgttca ccacaataat tctaaggcag ataaacttaa
      301 agagaaacct tcagaatggt ctaaaagaca tagaccacaa cattataagc atgaggatgc
      361 aaaagaaatg ccactgacat gggttcaaga tgagatttgg tgtcatgatt cctatgagag
      421 tgatggcaag tcagagaatt ggggaaattt tatagctaaa gaggaggaaa aacccaatca
      481 ccaggaatgg gactcaggag aacataccaa tgcctgtgtc cagcagaatt catcctttgt
      541 agacagaccc tataaatgtt ccgaatgttg gaaaagcttc agtaatagtt ctcatttgcg
      601 tactcaccag aggacccact caggagaaaa gccttataaa tgctctgagt gtgcaaaatg
      661 tttttgtaac agttctcacc tgattcagca tctaagaatg cacacaggag agaagcccta
      721 ccagtgtggt gaatgtggga aaagcttcag caatacctcc catcttatta tccatgagag
      781 aactcacacg ggagagaaac cctacaaatg tcccgagtgt gggaagagat tcagcagcag
      841 ctctcacctt attcagcatc acagatcaca tacaggtgaa aaaccatatg aatgttctgt
      901 ctgcggaaaa ggcttcagtc acagctatgt cctaatagaa catcagagga ctcacactgg
      961 agaaaaacct tataagtgcc ctgattgtgg gaagagtttt agtcagagtt ccagcctcat
     1021 tcgccaccag cggacacaca caggtgagaa gccctacaaa tgtcttgagt gtgaaaaaag
     1081 ctttggttgt aattctactc taataaaaca tcagagaata catacaggag aaaagcctta
     1141 tcaatgtcca gaatgtggga agaattttag tcgtagttca aaccttatta cacaccagaa
     1201 aatgcacaca ggagagaaat cctatgaaag ttctgaatat gaggaaagtt tgggtcagaa
     1261 ctgcaatgtg atagaagaat gcagaatcca gttaggagag aaaccatata gatgttgtga
     1321 atgtgggaag agttttggcc ttagctccca tctcattaga catcagagaa cacatacagg
     1381 agaaaaacct tacagatgtt ctgagtgctg gaaaactttc agtcagagtt ccaccctggt
     1441 gattcaccaa aggacacata caggagagaa accttataaa tgtcctgatt gtggtgaaag
     1501 cttcagtcag agctttaacc ttatcaggca ccggaggacc cacatagggg aaaaacctta
     1561 caaatgtacc agctgtgaga aatgcttcag cagaagtgcc tacctcagtc agcatcggaa
     1621 aattcacgta gaaaagcctt ttgagtctcc cgacgttggg gattttcctc atgaatggac
     1681 ttggaaaaac tgttcagggg aaatgccctt catctcttca ttttccgtct caaattcatc
     1741 ttcctgagtc ccaaagcctg gttggtgatg gttttttctt ccttgttgga ccatgacaat
     1801 ttaggtattc tgtgattgtt gtgctataaa gtttctttga tgtgtttgtc aaaacatttg
     1861 gaaaaagtca acctcccagt ttaaaggatg ggaagacccc aatcaccagg ttattggatc
     1921 tgtccagtga gagattcatc caccaaggat gaagaaagga ggacttttaa aaatttaagg
     1981 taagatagta atagcttcaa aagaacacat acagagtaat cctgagagta agcaaaggaa
     2041 ccatgagaac cgaagctaga attgctattg aattacttta ttttctcttc ccttattggg
     2101 tagagataca tcattactgg cctcaggggt ttacccaaag aaagggtatt tttgagcaaa
     2161 taatgtgatt tcctggctat tttgttgggg gcttaagatt tttttttttc aaatgcattt
     2221 ttagtcacta aaaattaact gtcgtaccat ctagaactat actgtccagt accatagcct
     2281 ctagccgtat gtagctattt gtattaagat taattgaaat tttaaatcca gttcctcagt
     2341 cacactagcc actttctaag tgctcagtag ctctgtgtga ccagcggcta ctgtattgga
     2401 tattatagaa ggttctttca ttcaagatca tcattcttga cagacccata aatatttcct
     2461 ataaagactg tagaagtgtg ttctggaggg tttgctctcc aaaaagaatt gtaatataga
     2521 gtagaattgg gatagagtat tgaagacact gggtttagac attggatatt ttaatgattg
     2581 tgtgttctaa ttcatgtgct gccaactgag ttatctagtg atatgacctc actgtcttga
     2641 ccaaagccag aatagaaggc aggattcctg aattctatct taaaatttgc aatgaagagc
     2701 cttttcccta aattatccca ttatgtaatt cttggtcagc tcaagaactg ggttcttttt
     2761 ctaataatta actcactaaa tctgagccag tgtccaagga cagtttgtca ttaaggagta
     2821 ctgagacttc ttagctttgg tactgacagt tttcttttgc ctcttgacat aattggtata
     2881 tggatctgat aactgaggtc ccatcttccc tactcattcc tatgggaatg atgctttgga
     2941 aattattaga tatatcctat tcccttcctc ccattttttt cctgctagtg caaaaggtag
     3001 atgagtagga agattaggac tcctgagttg cccatgattt catctaattt ttggattcag
     3061 aatgtatttt atgaataata tgcagagatg catattagga atgtgaagcc agaatgggtc
     3121 agttgtagct gctgcaaagt tctgtagctg atggtcattt aattgcatgg gggttatttt
     3181 atctttcatg attgtggtgc acctgatgct ggcggggtat ttgtgtgttt ttgtattgtt
     3241 atttgattac aaaaataaag caaaaactaa caaataaa
//
