LOCUS       NM_144976               2885 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens zinc finger protein 564 (ZNF564), mRNA.
ACCESSION   NM_144976
VERSION     NM_144976.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2885)
  AUTHORS   Yuan,L., Xu,H., Guo,R., Lu,T. and Li,X.
  TITLE     Long non-coding RNA ZFAS1 alleviates bupivacaine-induced
            neurotoxicity by regulating the miR-421/zinc finger protein564
            (ZNF564) axis
  JOURNAL   Bioengineered 12 (1), 5231-5240 (2021)
   PUBMED   34414857
  REMARK    GeneRIF: Long non-coding RNA ZFAS1 alleviates bupivacaine-induced
            neurotoxicity by regulating the miR-421/zinc finger protein564
            (ZNF564) axis.
REFERENCE   2  (bases 1 to 2885)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 2885)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 2885)
  AUTHORS   Kovacs,I.A., Luck,K., Spirohn,K., Wang,Y., Pollis,C., Schlabach,S.,
            Bian,W., Kim,D.K., Kishore,N., Hao,T., Calderwood,M.A., Vidal,M.
            and Barabasi,A.L.
  TITLE     Network-based prediction of protein interactions
  JOURNAL   Nat Commun 10 (1), 1240 (2019)
   PUBMED   30886144
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2885)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA619098.1 and BC028367.1.
            
            On Nov 22, 2018 this sequence version replaced NM_144976.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803615.136067.1, BC028367.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000339282.12/ ENSP00000340004.6
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 DA619098.1         63-70
            9-2885              BC028367.1         6-2882
FEATURES             Location/Qualifiers
     source          1..2885
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.2"
     gene            1..2885
                     /gene="ZNF564"
                     /note="zinc finger protein 564"
                     /db_xref="GeneID:163050"
                     /db_xref="HGNC:HGNC:31106"
     exon            1..153
                     /gene="ZNF564"
                     /inference="alignment:Splign:2.1.0"
     CDS             151..1812
                     /gene="ZNF564"
                     /codon_start=1
                     /product="zinc finger protein 564"
                     /protein_id="NP_659413.1"
                     /db_xref="CCDS:CCDS42505.1"
                     /db_xref="GeneID:163050"
                     /db_xref="HGNC:HGNC:31106"
                     /translation="MDSVASEDVAVNFTLEEWALLDPSQKKLYRDVMRETFRNLACVG
                     KKWEDQSIEDWYKNQGRILRNHMEEGLSESKEYDQCGEAFSQILNLNLNKKIPTIVRP
                     CECSLCGKVFMHHSSLSRHIRSHLGHKPYDYQEYGEKPYKCKQCGKAFSSCQSFRRHE
                     RTHTGEKPYACPECGKAFISLPSVRRHMIKHTGDGPYKCQECGKAFDRPSLFQIHERT
                     HTGEKPYECQECAKAFISLPSFQRHMIRHTGDGPYKCQECGKAFDRPSLFRIHERTHT
                     GEKPHECKQCGKAFISFTNFQSHMIRHTGDGPYKCKVCGRAFIFPSYVRKHERTHTGE
                     KPYECNKCGKTFSSSSNVRTHERTHTGEKPYECKECGKAFISLPSVRRHMIKHTGDGP
                     YKCQVCGRAFDCPSSFQIHERTHTGEKPYECQVCGKAFISLKRIRKHMILHTGDGPYK
                     CQVCGKAFDCPSSVRTHERTHTGEKPYECKECGKAFNYASSIRIHERTHTGEKPYECK
                     QCGKTFSYSSSFQRHERAHNGDKPYVKNVGKLSFITQPSNTCENE"
     exon            154..280
                     /gene="ZNF564"
                     /inference="alignment:Splign:2.1.0"
     exon            281..341
                     /gene="ZNF564"
                     /inference="alignment:Splign:2.1.0"
     exon            342..2885
                     /gene="ZNF564"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2515..2520
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF564"
                     /note="hexamer: AATAAA"
     polyA_site      2534
                     /gene="ZNF564"
                     /note="major polyA site"
     regulatory      2864..2869
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF564"
                     /note="hexamer: ATTAAA"
     polyA_site      2885
                     /gene="ZNF564"
ORIGIN      
        1 gtcttcctgt ttcgtgtccg ctgcgtttgg gttccggtct ccgcttctcc agtggccccg
       61 gtggctccac cgcagcgtct ggcgcgctgg gacctgcaca ggccggagag agccgtaggc
      121 aggaccccgg gacaccctgg aagccaggaa atggactcag tggcctctga ggatgtggct
      181 gtgaacttca cacttgagga gtgggctttg ctggatcctt cccagaagaa actctacaga
      241 gatgtgatgc gggaaacctt tagaaacctg gcctgtgtag gaaaaaaatg ggaagaccag
      301 agcattgaag attggtacaa aaatcagggg agaattttaa gaaatcatat ggaagaggga
      361 ctcagtgaaa gtaaagaata tgatcaatgt ggagaagcct tcagtcagat tctcaatctt
      421 aatctgaaca agaaaattcc tactatagta agaccatgtg aatgtagttt gtgtgggaaa
      481 gtcttcatgc atcattcatc ccttagtagg cacatcagat ctcaccttgg acacaaacca
      541 tatgactatc aggaatatgg agagaaacca tataaatgta agcagtgtgg gaaagccttc
      601 agttcttgtc aatcctttcg aagacatgaa agaactcaca ctggtgagaa accctatgca
      661 tgtccggaat gtgggaaagc cttcatttct ctcccaagtg ttcgaagaca catgattaag
      721 cacactggag atggaccata taaatgtcag gaatgtggga aagcctttga tcgcccaagt
      781 ttatttcaga tacatgaaag aactcacact ggagagaaac cctatgaatg tcaggaatgt
      841 gcaaaagctt tcatttctct tccaagtttt caaagacaca tgattaggca cactggagat
      901 ggaccttata aatgtcagga atgtggaaaa gcctttgacc gccccagttt atttcgaata
      961 catgaaagaa ctcatactgg agagaaaccc catgaatgta aacagtgtgg gaaggccttc
     1021 atttctttca caaattttca aagtcatatg attaggcaca ctggggatgg accttataaa
     1081 tgtaaagtat gtgggagagc ctttattttt cccagttatg ttcgaaagca tgaaagaact
     1141 catactgggg agaaacccta tgaatgtaat aaatgtggta aaaccttcag ttcttccagt
     1201 aatgttcgaa cacatgaaag gactcacact ggagagaagc cctatgaatg taaggaatgc
     1261 gggaaagcct tcatttctct cccaagtgtc cgaagacaca tgataaagca cactggagat
     1321 ggaccttata aatgtcaggt atgtggtaga gcctttgact gtcccagttc atttcaaata
     1381 cacgaaagaa ctcacactgg agagaaaccc tatgaatgtc aggtatgtgg gaaagccttc
     1441 atttctctta aaaggattag aaaacatatg atactgcaca ctggagatgg accttataaa
     1501 tgtcaggtat gtggtaaagc ctttgactgt cctagttctg tccgaacaca tgaaagaact
     1561 catactggag aaaaacccta tgaatgtaaa gaatgtggga aagcattcaa ttatgccagt
     1621 tccattagaa tacatgaaag aactcatacc ggagaaaaac cctatgaatg taagcaatgt
     1681 ggaaaaacgt tcagttattc cagttccttt caaagacatg aaagagctca taatggagat
     1741 aaaccttacg taaagaatgt gggaaagctt tcatttatca cacaaccttc gaatacctgt
     1801 gaaaatgaat agtggaggac aggtctacaa gtatctacat atctaaagaa tatggaaagt
     1861 cttcagtttg ctttctgggt ttcagacttg tttgggagct cacccctttc tcctgtttct
     1921 cacttttgga ataggaatct ctatcctgtg cctgtctcat attttggaaa tacatgacta
     1981 gtttggtttt caccggttcg gagctgaaga agaattttgc ctcagcatga attgagtctc
     2041 atccatatct gagtgatgtg atattgagat gacactttgg agtttgagtt taaacattag
     2101 gcttcatgct ggaattaact gagacttttg aggcctttgg gatgagatga atatatttta
     2161 catgtgatga catggatttt gggggccaga ggtgtaatgt tttggctgag tgtatgccac
     2221 ctcagattca tatgttgaaa ccttaccccc gtgccccccc tctcccccac aatgtgatgg
     2281 tatttggagg ccctgtctct ggtggttttt aggattggag gacatcatga agatggaggc
     2341 cttgtaattg ggattagttt cctgatagga atccctagag agctagcttt gcccttcacc
     2401 atgagagggt gcagtgagaa gatagctatc tttgaaccgg gaagcaggcc cttaccagac
     2461 atggactatg ccagtgcctt gatattggac ttcccagcct cccaaaccat gagaaataaa
     2521 tgtttgttga ttaattaagc tttccaattt atggtatttt gttttagcaa cccaagctaa
     2581 gacacaatcc aattttaaaa tggaggaaag gacttgaata gacatttctc caaagaagat
     2641 acccagatgg ccaataagca cgtaacaatg ctcgacatct ttagtcatta gggaaataca
     2701 aatcaaactc aagacataca tagcatctca ttaggattag tagtatcaaa gatggaaaac
     2761 aagaaatact gtcaaggatg tggaatgttg gagaacattg tgcactatca ctgggaatgt
     2821 acagtggtat aagcctgctg aaaacagtat ggcagatccc cagattaaaa tatagaaata
     2881 acata
//
