LOCUS       NM_024967               6574 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 556 (ZNF556), transcript variant
            1, mRNA.
ACCESSION   NM_024967
VERSION     NM_024967.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6574)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK021699.1, BC009374.2 and AC006130.2.
            
            On Nov 23, 2018 this sequence version replaced NM_024967.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK021699.1, SRR1660803.119357.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2145245
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000307635.3/ ENSP00000302603.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-425               AK021699.1         1-425
            426-1646            BC009374.2         403-1623
            1647-6574           AC006130.2         58176-63103
FEATURES             Location/Qualifiers
     source          1..6574
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.3"
     gene            1..6574
                     /gene="ZNF556"
                     /note="zinc finger protein 556"
                     /db_xref="GeneID:80032"
                     /db_xref="HGNC:HGNC:25669"
     exon            1..90
                     /gene="ZNF556"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..1458
                     /gene="ZNF556"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 556 isoform 1"
                     /protein_id="NP_079243.1"
                     /db_xref="CCDS:CCDS12097.1"
                     /db_xref="GeneID:80032"
                     /db_xref="HGNC:HGNC:25669"
                     /translation="MDTVVFEDVVVDFTLEEWALLNPAQRKLYRDVMLETFKHLASVD
                     NEAQLKASGSISQQDTSGEKLSLKQKIEKFTRKNIWASLLGKNWEEHSVKDKHNTKER
                     HLSRNPRVERPCKSSKGNKRGRTFRKTRNCNRHLRKNCCTSVRRYECSQCGKLFTHSS
                     SLIRHKRAHSGQKLYKCKECGKAFSRPSYLQTHEKTHSGEKPYACQSCGKTFLRSHSL
                     TEHVRTHTGEKPYECGQCGKGFSCPKSFRAHVMMHAGGRPYECKHCGKAFRCQKSFRV
                     HMIMHAGGRPYECKQCGKAYCWATSFQRHVRIHNGEKPYKCGKCGKAFGWPSSLHKHA
                     RTHAKKKPVSGGSVGKSSARPRPSTDVKSQTREKVYKCETCGKTYGWSSSLHKHERKH
                     TGEKPVNAASVGKPSGGLCSSKNVRTQIGQKPSKCEKCGKAFSCPKAFQGHVRSHTGK
                     KSCTSK"
     exon            91..217
                     /gene="ZNF556"
                     /inference="alignment:Splign:2.1.0"
     exon            218..401
                     /gene="ZNF556"
                     /inference="alignment:Splign:2.1.0"
     exon            402..6574
                     /gene="ZNF556"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3384..3389
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF556"
                     /note="hexamer: AACAAA"
     polyA_site      3408
                     /gene="ZNF556"
     regulatory      3560..3565
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF556"
                     /note="hexamer: ATTAAA"
     polyA_site      3587
                     /gene="ZNF556"
     regulatory      6554..6559
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF556"
                     /note="hexamer: ATTAAA"
     polyA_site      6574
                     /gene="ZNF556"
                     /note="major polyA site"
ORIGIN      
        1 gagtgaccac aggtgtcccc gtcgtgctca cctgcaccgg ctgcgaggag cagggagctc
       61 ctcaaagagc tcaggaacgg acaggacatg gacacagtgg tctttgaaga cgtggttgtg
      121 gatttcacgc tggaggagtg ggccttgctg aatcctgctc agagaaaact ctacagagat
      181 gtcatgctgg agaccttcaa gcacctggcc tcagtagata atgaggctca gcttaaagcc
      241 agtgggtcta tttctcagca ggatacttct ggagaaaaat tatccctcaa acagaaaata
      301 gaaaagttca caagaaagaa tatatgggcc tcccttttag gaaaaaattg ggaagaacat
      361 agcgttaaag acaagcacaa caccaaggag agacatttga gcagaaatcc aagggtggag
      421 agaccatgta aaagcagtaa aggtaataaa cgtggaagaa ccttcagaaa gactcgaaat
      481 tgtaatcgtc atctgcgcaa gaattgttgt actagtgtaa gacggtacga atgcagtcag
      541 tgtggaaaac tcttcaccca ttcctcatcc ctgataaggc acaaaagagc tcactctgga
      601 caaaaattat ataaatgtaa ggaatgtggg aaagccttca gtcgcccttc ctacctacag
      661 acgcatgaga aaactcacag tggagagaaa ccctatgcct gtcaatcttg cgggaagaca
      721 tttcttcgtt cccactctct cactgaacat gtaaggactc acactggaga gaaaccctac
      781 gaatgtgggc agtgtgggaa aggcttcagt tgtcccaaat cctttcgcgc acatgtgatg
      841 atgcacgccg gagggagacc gtatgagtgc aagcactgtg ggaaagcctt caggtgtcag
      901 aaatcctttc gagtccatat gatcatgcac gccggaggga gaccgtatga gtgcaagcag
      961 tgtgggaaag cctactgctg ggcaacatcc tttcaacgac acgtgagaat tcacaacggg
     1021 gagaaaccct ataagtgtgg aaaatgcggg aaagcattcg gttggccctc atccttacac
     1081 aaacacgcga gaacgcatgc taaaaagaaa cctgtgagtg ggggcagcgt gggaaagtct
     1141 tccgcgaggc ctcgcccctc cacagatgtc aaatcacaaa ctagagagaa agtctataaa
     1201 tgtgaaacgt gtgggaaaac gtatggttgg tcctcatctt tacacaaaca tgagagaaag
     1261 cacactgggg agaaacctgt aaatgcagcc agtgtgggaa aaccttcagg cgggctttgc
     1321 tcttccaaaa atgtaagaac gcagattgga cagaagccca gtaaatgcga aaaatgtggg
     1381 aaagctttca gttgtcccaa agcctttcaa ggtcatgtga gaagtcacac aggaaagaaa
     1441 tcctgtacat ctaagtaatg ggggaaaacc tgtgcaaatt aattcacata catggttcag
     1501 aaaattcaca gcaggagggc cgggcgcagt ggctcacgcc tgtaatccca gcactttggg
     1561 aggccgaggc aggcggatca cgaggtcagg agatcaagac catcctggct atggtgaaac
     1621 cccgtctcta ctaaaaaaaa aaaaaataca aaaaattagc cgggcgtggt ggcgggcacc
     1681 tgtagtccca gctgctcagg aggctgaggc aggagaacgg cgtgaacccg ggaggcggag
     1741 cttgcagtga gccgagatgg caccactgca ctccagcctg ggtgacagag cgagactcca
     1801 tctccaaaaa aagaaaattc atggcaggag aagaatctca tgacgtttat aaatatggta
     1861 ttgcctttat caggaccaca tcctaaaagt gggcctctag caaatgaatt tgcagttctc
     1921 ttgcaggtaa agttgagggg agaatcctgt aagtcctctc tcacctatag tactgaaatt
     1981 ttgatacata atggtttttt cttataaatt actaatgttt ctcttttcat ttagaagtgt
     2041 attgcaccca tgggtgatct gatgtatttt aatatgcatt aactttaatt tttatatatt
     2101 ttttttgtta ctccgtgtga ggccattaga ccaatgaaat atgggtgttt gttgacattt
     2161 tctgactggc cctgtgtgtt ccaagctgga tattactacc atgttacttt tattccacct
     2221 ttccatttta cagggaaaaa ctatttttaa tgttaatact ttctacttat acaggcaagt
     2281 aattcagtgg ctttatgcta ttggtcagag aatccttctt cattttgctt gtggactaat
     2341 aggtagttgg tagaaatacg tatgcatgca aattcttgga ggagtgtagt ctcgtgggaa
     2401 ctattttttt catctgttgc tgtttgctct ttgacctggc ttctgggttg gaattggaaa
     2461 ataggttttt ttgggttttt tttctttttc ttttttgaga cagagtcctg ttatgttgcc
     2521 caagctggag tgcaacggca cgatctcggc tcactgcaac ttccgcctcc cggtttcaag
     2581 cgattctcct gcctcagcct cccaagtagc tgggactata ggcatgcacc accatgtcca
     2641 gctaattttt gtatttttag tagagacggg gtttcaccat gttggccagg gtggtctcaa
     2701 actcctgaaa tctgcccgcc ttggcctccc aaagtgctgg gattacaggt gtgagccact
     2761 atgcctggcc atattatcat tatcttaata cctcattgtc tcagtatttc ttgtgcttct
     2821 gtgttcctgc ttccatgaca gatacaatgg tacaaccata aaaacacagg ggattgcggc
     2881 tgggcgcggt gactcacgcc tgtaatccca gcactttggg aggctgaggt gggcggatca
     2941 cgaggtcagg aaatcgagac catcctggct atcatggtga aaccccgtct ctactaaaaa
     3001 tacaaaaaat tagccaggtg tggtggcggg cgcctgtagt cccagctact cgggaggctg
     3061 aggcaggagg atggcgtgaa cctgggaggc gaagcttgca gtgagctgga atcgtgccac
     3121 tgtactccag cctgggcgaa agagcgagac tctgtctcaa aaataaataa ataaagaata
     3181 attttttaaa aaagcacagg ggattgtttc cctactgcat ctactgtgac ctagtattct
     3241 tcgtgagata aatcttacct ttcatgagaa aatgaaagac aatactggct tatcaggtaa
     3301 actctggaaa tttcctgtca catagagctg aatacaatct ctcagtatgt gttcagttat
     3361 tatgtttgat tatgtattat taaaacaaaa gtttctgttt ctgagaaata tctatttact
     3421 gtgtttgtgt ttttaaagaa gttggattct atacaaatgg ataaaatgtt tcttagaaat
     3481 agcctattta actgagtttt tcaaataagt tgtatactaa caaatgtcaa tctctgtttt
     3541 ttatttactg ggagaatgta ttaaaatatt gaaaattgcc aaatcaacat ggtgacttta
     3601 aaaatgatac ttctgggcca ggcacagtgg ctcacgcctg taatcccagc actttgggga
     3661 ggccaaggcg ggcagatcat gaggtcaaga gatcgagacc atcctggcta acacggtgaa
     3721 accccatctc tactaaaaat acaaaatatt agtggggtgt gctggtaggt gcctgtagtc
     3781 ccagctactc gggaggctga ggaaggagaa tggcttgaac ctgggaggcg gagcttgcca
     3841 agattgcgac actgcactcc agcctgggtg acagagcgag actccgtctc aaaaaaaaga
     3901 attatacttc tgaattaata ttaccagatg cattcagatt tagacatttt ctttctagta
     3961 catttgtttc ctatactgtt ataattttgt ctaagaaatt cttttttttt tttttgagac
     4021 agattctcgc tctgttaccc aggctggagt gcagtgccgt gatcttggct cactgcaacc
     4081 cccccgccaa ggttcaagtg attctcctac ctcagcctcc tgaagagctg ggattacagg
     4141 cacccgccac cacacccggc taatttttgt atttttagta gagacggggt ttcactatgc
     4201 tggccaggct ggtctcgatc tcctgacctt gtgatctgcc cacctcggcc tcccaaagtg
     4261 ctggggttac aggcgtgagc caccgcgccc agcctaataa attcttgttt attcataatg
     4321 acaaaaactt acgtaacggt tttataaatt taagtattaa ataagtctag caaaagacat
     4381 aaaaagataa ctaataaaac aagtttaaac tttattggag cccagtagca atggctcacg
     4441 cctgtaatcc caggacccac cgaggcgggt ggatcacctg atgtgaggag ttcgagacca
     4501 cgctggccaa catggtgaac atggtgaaac cttgtctcta ctaaaaatac aaaaaattgg
     4561 ccaggcgtgg tggcaggcgc ctgtaatccc agctacttgg gaggctgagg caggagaatc
     4621 gcttgaaccc gggaggcaga ggttgcagtg agccaagatt gcgccactgc actccagcct
     4681 gggcgacaag agtaagactc catctcaaaa aaaaaaaaat tttttttttg gataatatca
     4741 aggcagaata aagtatagta tcaaacttga caaggtagat aatagggaat gcagaataaa
     4801 ggatcgggct tcagtaagtg acaatctcat catgaattca tttatagttc caccatgtaa
     4861 tatgtcttaa atactatttc ttttttttta atactatttc aagaactgct catgagttag
     4921 gaaatagtga gcagtaatac agaaataacg gcaggaccag gggcagtggc tcacacttgt
     4981 aattccaaag cttcgggagg ctgaggcagg aggatcactt gagcacagga gttcaaggcc
     5041 agtctgggca catagtgaga cacagtctct ataaaaagaa atttttaaaa gtatctaggc
     5101 atggtgatgt gcacttgtag agccagctac tcaggaggct gagggtggag gatggcttga
     5161 gaccaagagg tccaggctgc aatgagttat cttgccactg tactccagcc agggtgacag
     5221 aatgagaccg tgtgtcaaat taaaaagaaa aaaagaaaca ataattattt ccctggccgg
     5281 gcgcggtggc tcacgcctgt aatcccagca ctttgggagg ctgaggcggg tggatcacga
     5341 ggtcaggaga tcaagaccat cctggctaac ccggtgaaac cctgtctcta gtaaaaaata
     5401 caaaaaatta gctgggcgtg gtggcaggtg cctgtagtcc cagctactcg ggaggctgag
     5461 gcaggagaat ggcgtgaacc caggaggcgg aacttgcagt gagcagagat cgaaccacta
     5521 cactccagcc tgggcgactg agtgggactc tgtctcaaaa aaaaaaagag acaaaaggta
     5581 tatttatggt tcagcctcat ttctgcaaat attaaaaatt ttagggcatg atgtatacat
     5641 tttatatata tatatatata gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgaatgt
     5701 gtgtgacgga gttttgctct gttgccaggc tggagtgcag tggtgcgatc tcagctcact
     5761 gcaacctcca cctcccaggt tcaagcgatt ctcctgcctc accctcccaa gtggctggga
     5821 atacaggcgt gccccgccac gcccagctaa ttttttgtat ttttagtaca ggtggggttt
     5881 caccttgttg gccaggatgg tctcgatctc ttcacctcgt gatctgcccg ccttggcctc
     5941 ccgcagagct gggattacag gcgtgagcca ccgcaccagg cccatgtcat atgtttttat
     6001 gagtttggac attggcatct gggaccaggt acttcatctg gatttgaacc acaatgtggg
     6061 tgtttgtttt taataccttt gtgaaataat tttaaattgc cttatatatt tggcattgtc
     6121 actttgctgc ccctacacac tgatggaaaa attgtgttct gcagaaaact agagttcctc
     6181 acagggtgag gaagagttat ggtcatctgc acagttgtag cccgttgcga gtgttttccc
     6241 atgtgcacag tgatatctag gcaagtgtgc catgatttcc tggtgaggat aaaatctatg
     6301 gacggtgaga gaactagtca aggaataact gaagtgagct gcagacagga ttatcatttt
     6361 gagtaacatc ccaatgtatt tgtcatcctt taattaattt ttattttttt aattaaaaaa
     6421 taatttttaa gtgtaaacct ttaatgatcc acaaagccca aaatgtccat ttgattttca
     6481 taggtatcgt ttccatatgc ttagacttcc agcagctatt agaagagaaa aatatgtaac
     6541 agctttgtgt ttaattaaag gcaaatgaaa tcca
//
