LOCUS       NM_024762               2352 bp    mRNA    linear   PRI 03-APR-2024
DEFINITION  Homo sapiens zinc finger protein 552 (ZNF552), mRNA.
ACCESSION   NM_024762
VERSION     NM_024762.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2352)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2352)
  AUTHORS   Deng,Y., Liu,B., Fan,X., Wang,Y., Tang,M., Mo,X., Li,Y., Ying,Z.,
            Wan,Y., Luo,N., Zhou,J., Wu,X. and Yuan,W.
  TITLE     ZNF552, a novel human KRAB/C2H2 zinc finger protein, inhibits AP-1-
            and SRE-mediated transcriptional activity
  JOURNAL   BMB Rep 43 (3), 193-198 (2010)
   PUBMED   20356460
  REMARK    GeneRIF: ZNF552 was a transcriptional repressor, and overexpression
            of ZNF552 in the COS-7 cells inhibited the transcriptional
            activities of AP-1 and SRE, which could be relieved through RNAi
            analysis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA345819.1 and AC010645.5.
            
            On May 20, 2006 this sequence version replaced NM_024762.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK097041.1, SRR1660809.12355.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000391701.1/ ENSP00000375582.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-470               DA345819.1         1-470
            471-2352            AC010645.5         16868-18749
FEATURES             Location/Qualifiers
     source          1..2352
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..2352
                     /gene="ZNF552"
                     /note="zinc finger protein 552"
                     /db_xref="GeneID:79818"
                     /db_xref="HGNC:HGNC:26135"
     exon            1..203
                     /gene="ZNF552"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..1394
                     /gene="ZNF552"
                     /codon_start=1
                     /product="zinc finger protein 552"
                     /protein_id="NP_079038.2"
                     /db_xref="CCDS:CCDS12963.1"
                     /db_xref="GeneID:79818"
                     /db_xref="HGNC:HGNC:26135"
                     /translation="MAAAALRFPVQGTVTFEDVAVKFTQEEWNLLSEAQRCLYRDVTL
                     ENLALMSSLGCWCGVEDEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGD
                     ILHVADHQGTHHKQKLHRCEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRC
                     KLHVSGESSVFSESGKDFLLRSGLLQQEATHTGKSNSKTECVSLFHGGKSHYSCGGCM
                     KHFSTKDILSQHERLLPTEEPSVWCECGKSSSKYDSFSNHQGVHTREKPYTCGICGKL
                     FNSKSHLLVHQRIHTGEKPYECEVCQKFFRHKYHLIAHQRVHTGERPYECSDCGKSFT
                     HSSTFRVHKRVHTGQKPYECSECGKSFAESSSLTKHRRVHTGEKPYGCSECEKKFRQI
                     SSLRHHQRVHKRKGL"
     exon            204..330
                     /gene="ZNF552"
                     /inference="alignment:Splign:2.1.0"
     exon            331..2352
                     /gene="ZNF552"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2331..2336
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF552"
                     /note="hexamer: AATAAA"
     polyA_site      2352
                     /gene="ZNF552"
                     /note="major polyA site"
ORIGIN      
        1 agtagcgacc atttccattg gcgttaggga gtccttggag cgctgtgttg ggaccgtggt
       61 ggtgactgga tccaggaggt cgagagtcgt tcttctcttt gcacagacgt gactctgcag
      121 ctctttaacg gcgcccgctg ctctcaaccc agcttacccc acgtggtccc atggcggcgg
      181 ccgcgctaag gttccccgtt cagggcacag tgacttttga agacgtggct gtgaaattta
      241 cccaggagga atggaatctc cttagtgagg ctcagagatg cctgtaccgt gatgtgacgc
      301 tggagaacct ggcacttatg tcctccctgg gttgttggtg tggagtggaa gatgaggcgg
      361 caccttctaa gcagagtatt tatatacaaa gagagactca ggtcaggact cctatggcag
      421 gtgtgtctcc caagaaggcc cacccctgtg agatgtgtgg cccgatcttg ggagacattt
      481 tgcatgtggc agatcatcag ggaacacatc acaagcagaa actgcacagg tgtgaggcct
      541 gggggaataa attgtatgac agtggaaact ttcatcagca ccagaatgag cacattggag
      601 agaaacccta cagagggagt gttgaggagg cgttgtttgc gaagaggtgt aagttgcatg
      661 tgtcagggga gtcatctgtc ttcagtgaga gtgggaaaga ctttttgctc aggtcaggat
      721 tactccagca agaggccact cacactggga agtcaaacag caaaactgag tgtgtgtctc
      781 tgtttcatgg gggaaaaagc cattacagct gtggaggatg catgaaacat tttagcacca
      841 aagatatact cagtcagcac gagagactgc tccctacaga agaaccttct gtgtggtgtg
      901 aatgtgggaa atcctctagc aaatatgaca gcttcagtaa tcatcaagga gttcacacta
      961 gagaaaaacc ttatacgtgt gggatatgtg ggaaattatt taacagtaag tcccacctcc
     1021 ttgtacacca gagaattcac actggagaga agccatatga gtgtgaggtt tgtcagaaat
     1081 tttttaggca caagtaccac ctcattgcac accagagagt tcacactgga gaaaggccat
     1141 atgaatgcag tgattgtggg aagtcattta cccacagctc tacattccgt gttcataaga
     1201 gagttcacac tggtcagaag ccttatgagt gcagtgaatg tgggaaatct tttgccgaaa
     1261 gctccagtct cactaaacac aggagagttc acactggaga aaagccttac gggtgcagtg
     1321 aatgtgaaaa aaaatttagg caaatctctt cacttcgtca tcatcagaga gttcacaaaa
     1381 gaaagggctt atgagtgcag tgagtccagt ctcattaaat attggagaat acacacctga
     1441 gtaagatcct gtgattgcag caaatgtgga aaatgtttac ccaaaggtct gctctccttg
     1501 gatattggag agttcacact agagaagagt ccttacaagt aaaataaatt tgggcagttt
     1561 tgtagccaca cctctgtatt ccttcaggat tatagttaac actgaatgaa ggccttacta
     1621 gtgtgacaaa tacaggatat ttatccagaa gtctggctgc ataactcaca ggagagctgt
     1681 catgtgggag gattgctaca tgggaggatt tgcttgagcc tgggaggcag aggttgcagt
     1741 gagccgagat tgcaacactg cagtccagtc tggaccacag agtgagaccc tgtttcaaaa
     1801 ataaaatata taaatgacat ccaataaagt atgcatattt gagctgtagg ataagtcttg
     1861 aattttcttt ttcttttttt tgagacagcc tcgctctgtc acccaggctg gagtacagtg
     1921 gcataatctc ggctcactgc aagccctgcc tcctgggttc atgccattct cctgcctcag
     1981 cctccctaat agctgggact acaggcaacc accaccactc ctaccttttt tgtattttta
     2041 gtagagatgg ggtttcaccc tgttagccag gaagttctca atctcctgac ctcgtgatct
     2101 gcccgccttg gcctctcaaa gtgttgggat tgcaggcgtg agccactgct cctggcttga
     2161 attttcttat aatcccatga aaccatcatc agagtcacaa taatgaattt atctaatcta
     2221 tcacctttgt attcacctgg agcctttata aagtttttct ctatgcagac aaccattgat
     2281 ttactctgct gtataatact ttccattttc tagaattttc tgactgatgt aataaagtgt
     2341 ttcctcttat aa
//
