LOCUS       NM_001397372            6587 bp    mRNA    linear   PRI 03-OCT-2024
DEFINITION  Homo sapiens zinc finger protein 550 (ZNF550), transcript variant
            5, mRNA.
ACCESSION   NM_001397372
VERSION     NM_001397372.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6587)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 6587)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC003682.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038192.3517292.1,
                                           SRR14038197.101089.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2155550 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000699333.1/ ENSP00000514306.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-208               AC003682.1         48368-48575         c
            209-335             AC003682.1         44943-45069         c
            336-431             AC003682.1         41339-41434         c
            432-6587            AC003682.1         30550-36705         c
FEATURES             Location/Qualifiers
     source          1..6587
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..6587
                     /gene="ZNF550"
                     /note="zinc finger protein 550"
                     /db_xref="GeneID:162972"
                     /db_xref="HGNC:HGNC:28643"
     exon            1..208
                     /gene="ZNF550"
                     /inference="alignment:Splign:2.1.0"
     CDS             182..1450
                     /gene="ZNF550"
                     /note="isoform a is encoded by transcript variant 5"
                     /codon_start=1
                     /product="zinc finger protein 550 isoform a"
                     /protein_id="NP_001384301.1"
                     /db_xref="CCDS:CCDS35500.2"
                     /db_xref="GeneID:162972"
                     /db_xref="HGNC:HGNC:28643"
                     /translation="MAETKDAAQMLVTFKDVAVTFTREEWRQLDLAQRTLYREVMLET
                     CGLLVSLGHRVPKPELVHLLEHGQELWIVKRGLSHATCAGDRAQVHTREPTTYPPVLS
                     ERAFLRGSLTLESSTSSDSRLGRARDEEGLLEMQKGKVTPETDLHKETHLGKVSLEGE
                     GLGTDDGLHSRALQEWLSADVLHECDSQQPGKDALIHAGTNPYKCKQCGKGFNRKWYL
                     VRHQRVHTGMKPYECNACGKAFSQSSTLIRHYLIHTGEKPYKCLECGKAFKRRSYLMQ
                     HHPIHTGEKPYECSQCRKAFTHRSTFIRHNRTHTGEKPFECKECEKAFSNRAHLIQHY
                     IIHTGEKPYDCMACGKAFRCSSELIQHQRIHTGEKPYECTQCGKAFHRSTYLIQHSVI
                     HTGEMPYKCIECGKAFKRRSHLLQHQRVHT"
     exon            209..335
                     /gene="ZNF550"
                     /inference="alignment:Splign:2.1.0"
     exon            336..431
                     /gene="ZNF550"
                     /inference="alignment:Splign:2.1.0"
     exon            432..6587
                     /gene="ZNF550"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5770..5775
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF550"
                     /note="hexamer: ATTAAA"
     polyA_site      5789
                     /gene="ZNF550"
                     /note="major polyA site"
     regulatory      6564..6569
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF550"
                     /note="hexamer: ATTAAA"
     polyA_site      6587
                     /gene="ZNF550"
                     /note="major polyA site"
ORIGIN      
        1 gggacttccg gcctcgctgg cgtggacgtt tgtggtgggg cgtgttggtc cgcgctctca
       61 gaactgtgct gggaaggatg gtagggcgac tggggctcac ctccgcaccg ttgtaggacc
      121 cggggtaggg ttttgagccc gtgggagctg ccccacgcgg cctcgtcctg ccaacggtcg
      181 gatggcggag acgaaggacg cagcgcagat gttggtgacc ttcaaggatg tggctgtgac
      241 ctttacccgg gaggagtgga gacagctgga cctggcccag aggaccctgt accgagaggt
      301 gatgctggag acctgtgggc ttctggtttc actagggcat cgggttccca aaccagagtt
      361 ggtccacctg ctagagcatg ggcaggagct gtggatagtg aagagaggcc tctcacatgc
      421 tacctgtgca ggtgacagag cacaagttca taccagagag ccaaccactt acccgccagt
      481 cttatctgag cgggcctttc tccggggaag cctgactctg gaatcttcaa cctcaagtga
      541 ttcgaggttg gggagagcta gggatgagga agggcttttg gaaatgcaga aaggtaaagt
      601 gacaccggag acagacctcc acaaggagac ccatcttggg aaagtgagcc ttgaaggtga
      661 aggtttgggg acagatgatg gtctgcactc cagggcatta caagagtggt tatcagcaga
      721 tgttctccat gaatgtgact cacagcaacc agggaaagac gccttgattc atgcagggac
      781 aaacccctac aaatgcaagc agtgtgggaa aggttttaac aggaagtggt atctcgttcg
      841 acatcagagg gttcacactg gaatgaaacc ctatgaatgc aatgcatgtg ggaaagcctt
      901 tagccagagc tcaactctca ttcggcacta cctcatccac accggggaga aaccatacaa
      961 gtgccttgag tgtgggaagg ccttcaaacg caggtcgtac ctcatgcagc accatccaat
     1021 ccacactgga gagaaaccct atgagtgtag tcaatgtcga aaggccttca cccaccggtc
     1081 tacttttatt cgccataata ggacccacac tggagaaaag ccctttgagt gcaaagaatg
     1141 tgagaaagcc tttagcaata gagcccacct aattcaacat tacatcatcc acactggaga
     1201 gaagccctat gattgcatgg catgtggaaa ggccttcaga tgcagctcag aactcataca
     1261 gcaccagcgg attcacactg gggagaagcc ctatgaatgc acccagtgtg ggaaagcctt
     1321 tcaccggagc acgtacctca ttcagcactc tgtcatccac actggggaga tgccctacaa
     1381 gtgtatcgag tgtgggaagg ccttcaaacg caggtcacac cttctgcagc accaaagggt
     1441 ccatacatga gagaacccta ttgctgcaat gaatacagca aggcctttac ccactgttat
     1501 tttatcattc ataatgggac ccacactgta ggaagaagtc cttcgaatgc aaagaatgtc
     1561 aggaaacttt tcattttttt tgtcagctct ttcttaacta acacatgagc agtcactttg
     1621 gagagaagcc ctgtgaatac agtgaatgta aggatccctt cagtcaccac tcagttctca
     1681 ctcattgcag aaggattcat accaggggga aatgtggaag gcattccatc aacatcagag
     1741 aactcatgct ggagaaagac attccaaata taactattaa ggacagtctt tggccagagc
     1801 agaaatctta ctatctgaga atcataatga aaagttacta cataattgtt attgatgtga
     1861 gaaaactttg tgaccaggtt gtcacttgct tgtcctataa agagccatgc tggaatttga
     1921 cccaccttgg gattttctct atgaacttat gaaaaccttc agttacaggt atcttcttgc
     1981 tttatgtcct tacagacttc cctgtaagat cagttttatt ttttggtagg ggaatgtttg
     2041 agaggtaaag gggttttatt cctttttttt ttttttaaca tacattcact gccatccttt
     2101 gtcagagtta gacagtgagg gcagctcttc aggcatttct tggaagttgc ctttgatcca
     2161 gacatctctg ggaggatatc catgaggaga gtaattcttt gtgagaaata tgaaggcttg
     2221 tgtcatgaga ttcttgaatt tagtagaaat tagaatactg agaacatctt catgtgacac
     2281 ttctttttta tatctagggt gagaagaacc catgtacaga tggccacatt aaaatgtgca
     2341 ccacattaaa atgtgcaata cctaagactg tttaaggctt tgatttttat taataaactc
     2401 attatttttt aagagacagg gacttgctct gtcacccagg ctagagtgca gtggcatgat
     2461 catagttccc tgtaacctcg aactcctggg ctcaaatggt cctcttgcct caagtttctg
     2521 agtagcttgg gatacaggca tacaccacta cgcctggcta atgtttgtaa ttttagtaga
     2581 gacaaggttt taccatgttg gctgggctgg tctggaactc ctggcttcaa gtggtccacc
     2641 tgccttggcc tcccaaagtt ctgggattac aggtgtgagt cactgcaccc agccttaaat
     2701 ttttttgtat agatgaggtc ttgctgtgtt ccccagattt gtctcaaact gctagactca
     2761 agtcatcatc ctgcttagcc tcctaaagtg ttgggattac aggtgtgagc caccacacct
     2821 agcctaatat ggtttcaaat gctcagcact ctcacatttt cctgattcca ttctgtctgt
     2881 ttgttgtctt tattttctct ggcaacatag tgatcacttt gtacttgctt ggccttctca
     2941 gatgagtcct aattctttct ggtgtttatc agattcttta atcctgtgta gaggggtatt
     3001 tttaggtccc cctcagcatt tttctaggga ttgaattata gctaaaacag gcaaaataaa
     3061 acacacaact aagatgaatc catggtaaac ccagtaaacc caagaaaaca acatggagag
     3121 gaatctcatt gtctgatctt ataaacattt gcgtgaagtt ttgctacaaa ataaagtgcc
     3181 tagcatttta acaggtgaat caggatatac gtgggcaggt ttacgtgagt ttcatagtta
     3241 accaccatga ccttagtccc ttggtgctag cactgaatat ggtaattagt tttgttgtgt
     3301 tttgagatgg agtctcactc cgctgcctag gctggagtgc aggagtgcga tcttggctca
     3361 ttgcaacctc tgcctcccgg gttcaagcga ttctcctgcc tcagcctccc aagaagctgg
     3421 gattacaggc atgtactacc atgcccagct aatttttgta tttttagtag agacagggtt
     3481 ttgccatgtt gcccaggctg gtctcgaact cctgacctca ggtgatccac ccacctcagc
     3541 ctgccaaaaa gctgggatta caggtgtgag ccactgtact tagcctgaat ctggtaattt
     3601 gaaattcctt ttgtgagatt ttcttttagt tttcaagcta catgagataa tgttaggtta
     3661 aaacgtgtga aaaatagaaa attatcattt tctcactttg agctttcctc acaacctttt
     3721 aaagcactgc atatatattc atgttttcat agtgggcatg taccttttac tgtggtcctt
     3781 ttgcacatat tataaataga attcttggtg agttaagagt tctctgtttt tgttttttca
     3841 ggacagagtg cacagtttcc tctcctgtgg gaaggagagt tgactcttga ggacccccac
     3901 cctcctgcat cctctctctg gaaggctgca tgtattgtag ctgtggctgt acttgtacct
     3961 aaggccctgg gttcaagaga gttggagaaa cccctctaga aacatattgg ctgtcatcaa
     4021 agggttcttt ccaggcctga ggacctaggc cccagtttgt cccaaagcag gagtgttttc
     4081 catgggataa aggacaccct aggtttttct tagcttccag ctctttccat acagtcttca
     4141 ctgaagtgtt tggtacaagg atctactatg aacttgctgc tgtgataggc aagaatctca
     4201 tgagacacct gtcatttagc tccatggcca ctcactgttg tggtcatact tagaagagtg
     4261 ggatgcagtg gatggctggg ctatgggtcc tgcccttgag cagggaagga acttactgtc
     4321 taatatagga aaaacacatg agaacaggtg caatatattg acttaaactt gtttagcacc
     4381 cgtttttaag tcagtagaag ttttgaactt acagtaaaag ttgtgaactt ctgtatgttt
     4441 tccacagttt atgattgagg taaaacatgt tttttgtttt gtttttgaga cagagtttca
     4501 ctcttgttgc ccaggctgga gtgcagtggc gccatctcag ctcactgcaa cttctgcctc
     4561 ccgagttcaa gggattctcc tgcctcagcc tcccgagtag ctgggattac aggcgcccac
     4621 caccatgccc ggctagtttt tttgtatttt tagtagagac ggggtttcac catgttggcc
     4681 aggctggtct tgaactcttg acctcatgta gtccacccgc ctctgcctcc caaagtgctg
     4741 cgattacagg cgtgagccac cgtgcccggc agaggtaaaa cgttttcatg ttcatgtttt
     4801 tgtaactttg ttacatttaa tgaacaaatt agataaaaag cactatgctc ttatgctgct
     4861 taatctgtga gaaatgattg tgggggtggg actagttatg accattcaca gttggtgcac
     4921 ttcaatcagt aaatgtcaca gaggaaatgt ggacggtaaa ttaactcggc aagtcggtca
     4981 tgcaaagacg aattagaaat cttaatattt gtaagcagac aaaaaatgtg tctggaagga
     5041 tcctcaccca gttaaatggt atttgctcct tgggtgtaga gggagggaag ggatggggta
     5101 gaggggaatg tcagagttca ctttaacttc atgcacatgt ggaaatgttt gaaatgttca
     5161 cagtaaattt tataatttca gaaaaactgc ttaaggttga aaagagaaat ttaagaaatt
     5221 gctgacggaa taaaaacata atagaactac aacaccgaag gaaatgaaag aagcaagaag
     5281 gaaagcacca gaagtgattt ggaagagaaa tcctaaaatg aatgtgaaca acagagtgat
     5341 cagaagagtg tagggaatta atagtttctt taaacaagcc atctcacaat ggaagcctgt
     5401 gtgtcttgaa attgctgtgg ttattattca ctctgccctt tgaagaactg cagaaattca
     5461 tagggcaatg ttaagtgttt gtgtctccaa aaaagatgtt ggagtcgtta ccctcagaac
     5521 ctcaggtaat catgttagtt aatccattag gttagttcct aattgactat gactgtgtcc
     5581 ttagaaaaat gggaaatttg gtcacagagg cagatgtaca gagggaagac gatgtgaaga
     5641 cacaggaaga acatcttcaa gccaaggaac acacggggct accagaagcc gagatagaag
     5701 catggaacat atgttctagt aagaagtgtc tgggttgttt tggttttttt tctttggagt
     5761 ttttgtggta ttaaattatt tttaaattat gttttattgt agacctcaca attctttttt
     5821 tttctttttc actcaaacta cagcaaaata ttatatttct atcctatatt tcatgggctt
     5881 acctctagcc aattgttttt aactgccatg taatatttta catcatgaag ctttcatcct
     5941 tgattcaaat cctctgatta tggacatgta tttcctccat tttcctgcta tgaaatatat
     6001 caccaccagc ttgattcaac cttaaaaata aggtcatcag tattatgttc taaataaact
     6061 tatggccata catgagaaat gtaccttgca gctgaatggc taggtcatat ggtgatctag
     6121 tatgtaactg gaattatgtt atacattgcc cttcctctcc cataagatgg acaaaagtgt
     6181 ttctgtatca ctgtgtccca gacaatattt agaattaccc agctttccag tttttacttt
     6241 agaagtttaa agtgatatag aatatatctg gtatttctca tattgaaata catttgaaca
     6301 ttagttcata tcctttcatt gccttttgtt tttcctcttc tgtcaatggt ctactcatat
     6361 gttggcctgt ctttatttgt atcttgactt tttattgtgt attttgttta tggtggggta
     6421 ctttattggt gattaatacg attttcaagt atattatatg ggctagtccc ttgatactat
     6481 tgacactgta tttatcttca gtctcttgtt ggtatctaac tttggttctg aagtttatgg
     6541 aatggaagta tttaattgga aagattaaac atattgattt taattaa
//
