LOCUS       NM_173631               2754 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens zinc finger protein 547 (ZNF547), mRNA.
ACCESSION   NM_173631
VERSION     NM_173631.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2754)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC003002.1 and BC042681.1.
            
            On Nov 30, 2019 this sequence version replaced NM_173631.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC042681.1, AL832545.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000282282.4/ ENSP00000282282.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                AC003002.1         13287-13306
            21-1820             BC042681.1         6-1805
            1821-2181           AC003002.1         28368-28728
            2182-2748           BC042681.1         2167-2733
            2749-2754           AC003002.1         29296-29301
FEATURES             Location/Qualifiers
     source          1..2754
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..2754
                     /gene="ZNF547"
                     /gene_synonym="MIP-2A; SEDLP1; TRAPPC2.19; TRAPPC2B;
                     TRAPPC2P1"
                     /note="zinc finger protein 547"
                     /db_xref="GeneID:284306"
                     /db_xref="HGNC:HGNC:26432"
     exon            1..153
                     /gene="ZNF547"
                     /gene_synonym="MIP-2A; SEDLP1; TRAPPC2.19; TRAPPC2B;
                     TRAPPC2P1"
                     /inference="alignment:Splign:2.1.0"
     exon            154..189
                     /gene="ZNF547"
                     /gene_synonym="MIP-2A; SEDLP1; TRAPPC2.19; TRAPPC2B;
                     TRAPPC2P1"
                     /inference="alignment:Splign:2.1.0"
     CDS             166..1374
                     /gene="ZNF547"
                     /gene_synonym="MIP-2A; SEDLP1; TRAPPC2.19; TRAPPC2B;
                     TRAPPC2P1"
                     /note="Trafficking protein particle complex subunit 2B;
                     MBP-1-interacting protein 2A"
                     /codon_start=1
                     /product="zinc finger protein 547"
                     /protein_id="NP_775902.2"
                     /db_xref="CCDS:CCDS33131.1"
                     /db_xref="GeneID:284306"
                     /db_xref="HGNC:HGNC:26432"
                     /translation="MAEMNPAQGHVVFEDVAIYFSQEEWGHLDEAQRLLYRDVMLENL
                     ALLSSLGCCHGAEDEEAPLEPGVSVGVSQVMAPKPCLSTQNTQPCETCSSLLKDILRL
                     AEHDGTHPEQGLYTCPAHLHQHQKEQIREKLSRGDGGRPTFVKNHRVHMAGKTFLCSE
                     CGKAFSHKHKLSDHQKIHTGERTYKCSKCGILFMERSTLNRHQRTHTGERPYECNECG
                     KAFLCKSHLVRHQTIHSGERPYECSECGKLFMWSSTLITHQRVHTGKRPYGCSECGKF
                     FKCNSNLFRHYRIHTGKRSYGCSECGKFFMERSTLSRHQRVHTGERPYECNECGKFFS
                     LKSVLIQHQRVHTGERPYECSECGKAFLTKSHLICHQTVHTAAKQCSECGKFFRYNST
                     LLRHQKVHTG"
     exon            190..316
                     /gene="ZNF547"
                     /gene_synonym="MIP-2A; SEDLP1; TRAPPC2.19; TRAPPC2B;
                     TRAPPC2P1"
                     /inference="alignment:Splign:2.1.0"
     exon            317..2754
                     /gene="ZNF547"
                     /gene_synonym="MIP-2A; SEDLP1; TRAPPC2.19; TRAPPC2B;
                     TRAPPC2P1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1628..1633
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF547"
                     /gene_synonym="MIP-2A; SEDLP1; TRAPPC2.19; TRAPPC2B;
                     TRAPPC2P1"
                     /note="hexamer: AATAAA"
     polyA_site      1655
                     /gene="ZNF547"
                     /gene_synonym="MIP-2A; SEDLP1; TRAPPC2.19; TRAPPC2B;
                     TRAPPC2P1"
                     /note="major polyA site"
     regulatory      1904..1909
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF547"
                     /gene_synonym="MIP-2A; SEDLP1; TRAPPC2.19; TRAPPC2B;
                     TRAPPC2P1"
                     /note="hexamer: CATAAA"
     polyA_site      1923
                     /gene="ZNF547"
                     /gene_synonym="MIP-2A; SEDLP1; TRAPPC2.19; TRAPPC2B;
                     TRAPPC2P1"
     regulatory      2023..2028
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF547"
                     /gene_synonym="MIP-2A; SEDLP1; TRAPPC2.19; TRAPPC2B;
                     TRAPPC2P1"
                     /note="hexamer: ATTAAA"
     polyA_site      2047
                     /gene="ZNF547"
                     /gene_synonym="MIP-2A; SEDLP1; TRAPPC2.19; TRAPPC2B;
                     TRAPPC2P1"
                     /note="major polyA site"
ORIGIN      
        1 gtacgcagag gcggtagtga cacaggcaca actgacagtg gcagaagctc agctgacaag
       61 gactggggac ggcggtgtcc ttgtcttgcc tttgtcgccc ccgcccctct cttccctggc
      121 tggacttgcg gagtccccgc cgaagaaccc gagggtcccc tggcgatggc agaaatgaac
      181 cctgcacagg gtcatgtggt ttttgaagac gtggccatat atttctccca ggaggagtgg
      241 gggcatctcg atgaggctca gagattgctg taccgtgatg tgatgctgga gaatttggcc
      301 cttttgtcct cactaggttg ttgccatgga gctgaggatg aggaggcacc tttagagcca
      361 ggtgtttctg taggagtgtc acaggtcatg gctccaaagc cctgtctatc tacccagaat
      421 acccagccct gtgagacatg tagctcactt ctgaaggaca ttctgcgtct ggctgagcat
      481 gacggaacac accccgagca gggactgtac acgtgtccag cacatcttca ccagcaccaa
      541 aaggagcaga ttagagagaa actttctaga ggggatggag gaagaccgac atttgtgaag
      601 aaccacagag ttcacatggc agggaagacc ttcttgtgca gtgaatgtgg gaaagccttt
      661 agccacaaac ataaactttc tgaccatcag aaaatccaca ctggagaaag aacttataag
      721 tgcagcaaat gtgggatatt gtttatggaa aggtccacac tcaatagaca tcagagaact
      781 cacactggag aaaggcctta tgagtgcaat gaatgtggga aagcctttct ttgtaagtct
      841 caccttgttc gtcaccagac aatccactct ggagaaaggc cttatgagtg cagtgaatgt
      901 gggaaattgt ttatgtggag ttccacactc attacacatc agagggttca cactggaaag
      961 aggccttatg gttgcagtga atgtgggaag ttctttaagt gcaactcaaa cctctttagg
     1021 cattacagaa ttcatacagg aaaaaggtct tatggttgca gtgaatgtgg gaaattcttt
     1081 atggaaaggt ctacactcag tagacatcag agagttcaca ctggagaaag gccttatgag
     1141 tgcaatgaat gtgggaaatt cttcagcttg aaatccgtcc tcattcaaca ccaaagagtt
     1201 cacactggag aacggcctta tgaatgcagt gagtgtggga aggccttcct tacaaagtcc
     1261 cacctcattt gtcatcagac agttcacact gcagcaaagc agtgcagtga atgtgggaaa
     1321 ttctttaggt ataactctac acttctcaga catcagaaag tccacactgg ataaggccct
     1381 tatgaatgca gtggatatgg gaaagccttc agtcaccaac atattgtggc tggacagcag
     1441 gcagtacaca ctggagaaag actgaatgcc gtgaacgtgg gtaattatgt aggtacagct
     1501 ctccagtcgc tatgtatcag agaattcaca ctgcagaaat gtgtgttcag caaactcggg
     1561 acattatttt ggtttgactc tcatctcatt agacattgga gagtttacac tgaagaagag
     1621 tcttttcaat aaagtagaaa gtggtaaaga ttcaacatgc aagattgtac ttattgggct
     1681 tcagaatatc cacactagtg aaagtcttct gagtacagca aatgtgtgac attattttgc
     1741 tactactcca cactacttag acatcatgta gttcacactg gaaaaaggcc acgtatgtgc
     1801 cttgaatgta gccaaaatga cgaacaacac ccagaaatct gtgatttagc actgagaact
     1861 agtattatat ggtttttaaa aaacaatggt gaagtacatg ccacataaaa tttgccatct
     1921 taactattgt aatgtcttgt ttaatacttg aagtacatta acattgttga gcaaagaata
     1981 tcctgaactc tttatcttgt aaaatgaaac tctataacca ccattaaaaa aacaactcat
     2041 tcccacattc ttcagtccct ggcgaccacc atatttttaa gtcattatga ctctgactat
     2101 tcttggtact tctcagaaga agaatcttag agtgtttttc attatttttt ttcacttagg
     2161 ataatatcct caaagttcat tcatttttta gcatgtgtca gaaattttaa ggctgagcaa
     2221 tatttcattg tttgcattta ccacatttcc tttatttctg acatctattc atggacactt
     2281 gggttacttc tacctctggc tattgtgaat attgctacta caagcataag ggcacaaata
     2341 tctctttgag accctgcttt caattcttat tgggtacccc aaaaagtgga actgctggat
     2401 cacatggtac ttctaacttt aattctttga tgaactgaga aacttttcca taaaacttgc
     2461 accgttttac attcctaaca ttccacaaaa gttgtgattt gtcctcattc taatccatag
     2521 aaggcaacat ttctaacagg tttctaggtg attttgttgt tgctgatgta gggactacat
     2581 tttgagaact gtcctatccc atttttataa caatgcagag cttctctgta aatacccctt
     2641 gtttctatgt tctatcctgt gagccttttc attttgttaa tttttcccag tgtttacaac
     2701 caggaaatag cttgtcatct ttgatacaaa acagaaatct ttgcaaaata ccaa
//
