LOCUS       NM_014480               3302 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens zinc finger protein 544 (ZNF544), transcript variant
            1, mRNA.
ACCESSION   NM_014480
VERSION     NM_014480.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3302)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3302)
  AUTHORS   Sugis,E., Dauvillier,J., Leontjeva,A., Adler,P., Hindie,V.,
            Moncion,T., Collura,V., Daudin,R., Loe-Mie,Y., Herault,Y.,
            Lambert,J.C., Hermjakob,H., Pupko,T., Rain,J.C., Xenarios,I.,
            Vilo,J., Simonneau,M. and Peterson,H.
  TITLE     HENA, heterogeneous network-based data set for Alzheimer's disease
  JOURNAL   Sci Data 6 (1), 151 (2019)
   PUBMED   31413325
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3302)
  AUTHORS   Lasky-Su,J., Neale,B.M., Franke,B., Anney,R.J., Zhou,K.,
            Maller,J.B., Vasquez,A.A., Chen,W., Asherson,P., Buitelaar,J.,
            Banaschewski,T., Ebstein,R., Gill,M., Miranda,A., Mulas,F.,
            Oades,R.D., Roeyers,H., Rothenberger,A., Sergeant,J.,
            Sonuga-Barke,E., Steinhausen,H.C., Taylor,E., Daly,M., Laird,N.,
            Lange,C. and Faraone,S.V.
  TITLE     Genome-wide association scan of quantitative traits for attention
            deficit hyperactivity disorder identifies novel associations and
            confirms candidate gene associations
  JOURNAL   Am J Med Genet B Neuropsychiatr Genet 147B (8), 1345-1354 (2008)
   PUBMED   18821565
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA193549.1, AK291656.1, BC067271.1 and AL833618.1.
            
            On Aug 13, 2020 this sequence version replaced NM_014480.3.
            
            Transcript Variant: This variant (1) encodes isoform 1. Variants
            1-3 and 21-23 all encode the same isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF020591.1, SRR14038195.99604.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000687789.1/ ENSP00000510489.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                DA193549.1         321-335
            16-1334             AK291656.1         1-1319
            1335-2848           BC067271.1         1296-2809
            2849-3302           AL833618.1         2811-3264
FEATURES             Location/Qualifiers
     source          1..3302
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..3302
                     /gene="ZNF544"
                     /note="zinc finger protein 544"
                     /db_xref="GeneID:27300"
                     /db_xref="HGNC:HGNC:16759"
     exon            1..33
                     /gene="ZNF544"
                     /inference="alignment:Splign:2.1.0"
     exon            34..136
                     /gene="ZNF544"
                     /inference="alignment:Splign:2.1.0"
     exon            137..205
                     /gene="ZNF544"
                     /inference="alignment:Splign:2.1.0"
     exon            206..297
                     /gene="ZNF544"
                     /inference="alignment:Splign:2.1.0"
     CDS             265..2412
                     /gene="ZNF544"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 544 isoform 1"
                     /protein_id="NP_055295.2"
                     /db_xref="CCDS:CCDS12973.1"
                     /db_xref="GeneID:27300"
                     /db_xref="HGNC:HGNC:16759"
                     /translation="MEARSMLVPPQASVCFEDVAMAFTQEEWEQLDLAQRTLYREVTL
                     ETWEHIVSLGLFLSKSDVISQLEQEEDLCRAEQEAPRDWKATLEENRLNSEKDRAREE
                     LSHHVEVYRSGPEEPPSLVLGKVQDQSNQLREHQENSLRFMVLTSERLFAQREHCELE
                     LGGGYSLPSTLSLLPTTLPTSTGFPKPNSQVKELKQNSAFINHEKNGADGKHCESHQC
                     ARAFCQSIYLSKLGNVETGKKNPYEYIVSGDSLNYGSSLCFHGRTFSVKKSDDCKDYG
                     NLFSHSVSLNEQKPVHFGKSQYECDECRETCSESLCLVQTERSGPGETPFRCEERCAA
                     FPMASSFSDCNIIQTTEKPSVCNQCGKSFSCCKLIHQRTHTGEKPFECTQCGKSFSQS
                     YDLVIHQRTHTGEKPYECDLCGKSFTQRSKLITHQRIHTGEKPYQCIECRKSFRWNSN
                     LIVHQRIHTGEKPYECTHCGKSFSQSYELVTHKRTHTGEKPFKCTQCGKSFSQKYDLV
                     VHQRTHTGEKPYECNLCGKSFSQSSKLITHQRIHTGEKPYQCIECGKSFRWNSNLVIH
                     QRIHTGEKPYDCTHCGKSFSQSYQLVAHKRTHTGEKPYECNECGKAFNRSTQLIRHLQ
                     IHTGEKPYKCNQCNKAFARSSYLVMHQRTHTGEKPFECSQCGKAFSGSSNLLSHHRIH
                     SGEKPYECSDCGKSFRQQSQLVVHRRTHTGEKP"
     exon            298..424
                     /gene="ZNF544"
                     /inference="alignment:Splign:2.1.0"
     exon            425..508
                     /gene="ZNF544"
                     /inference="alignment:Splign:2.1.0"
     exon            509..3302
                     /gene="ZNF544"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3280..3285
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF544"
                     /note="hexamer: AATAAA"
     polyA_site      3302
                     /gene="ZNF544"
                     /note="major polyA site"
ORIGIN      
        1 accggaagca ccgccattgg ccggtgcgtg caggtggcag ccaagagcct cctggcacag
       61 cggcaccagg caggtgacgc ctattggacc ccagaggtca tcccagctcc agacgtggac
      121 acattttctt ccaatgatgt ctacggatga ggaaactgag gcctggagag gttaaagaga
      181 cccgttcaga gtcctacagt ggcagactgg tcttctgagg acctctgccc tctacacagc
      241 ggcctcttca ggtgcaggga ggaaatggaa gcacgttcta tgctggttcc accccaggca
      301 tctgtgtgct tcgaggatgt ggctatggca ttcacacagg aggagtggga acagctggac
      361 ctggcccaga ggacactgta ccgagaggtg acactggaga cctgggagca tattgtctcc
      421 ctggggcttt tcctttccaa atctgatgtg atctctcagc tggagcaaga agaggacctg
      481 tgcagggcag agcaggaggc cccccgagac tggaaagcta cccttgagga gaataggttg
      541 aattctgaaa aagatcgagc tagggaagaa ctatcccacc acgtggaagt gtacaggagt
      601 ggaccggagg agccaccctc tttggtatta ggaaaagtgc aagatcagag caaccagtta
      661 agggaacacc aggagaactc cttgaggttc atggtactca cctcagagag actgtttgct
      721 caaagggaac attgtgagct tgaacttggg ggaggttatt ctctaccttc tactttaagc
      781 cttctaccta caacattacc tacaagtaca ggtttcccta agcccaactc acaagttaaa
      841 gagttgaaac aaaattcagc tttcattaat catgagaaaa atggagcaga tgggaagcac
      901 tgtgagagtc atcagtgtgc tagagctttc tgtcagagta tttacttgag taaacttgga
      961 aacgttgaaa caggaaagaa aaacccttat gaatatattg tcagtggtga ctctctcaac
     1021 tatggttcct ccctttgttt tcatggtaga actttttcag tgaagaaaag tgatgactgt
     1081 aaggattatg gaaacctctt cagtcacagt gtgtctctga atgaacagaa gccagtgcat
     1141 tttgggaaaa gtcagtatga gtgtgatgag tgcagggaaa cctgttctga gagtctgtgc
     1201 cttgtacaaa cagaaagaag tggccctgga gagaccccct tcagatgtga ggaacgctgt
     1261 gctgccttcc ccatggcctc atctttttct gactgtaaca tcattcagac tacagagaag
     1321 ccatctgtgt gtaatcagtg tggaaaatct ttcagctgtt gtaagctcat acaccagaga
     1381 acacacactg gagaaaagcc cttcgaatgt actcagtgtg ggaaatcttt tagccagagc
     1441 tatgaccttg tcatacatca gaggacacac actggagaga agccctatga gtgtgacctg
     1501 tgtgggaaat ccttcaccca gagatccaaa cttattacac atcagcgaat tcacactgga
     1561 gaaaaaccgt atcagtgtat tgaatgcaga aaatccttca ggtggaactc taacctcatt
     1621 gtacatcaga gaattcatac tggagagaaa ccgtatgagt gcactcactg tggaaagtcc
     1681 ttcagccaaa gctatgagtt agttacacat aaaagaacgc acactggaga aaaacccttc
     1741 aaatgtactc agtgtgggaa atctttcagc cagaagtatg accttgttgt acatcagagg
     1801 acacacactg gagagaagcc ctatgagtgc aacctgtgtg ggaaatcctt ctcccagagt
     1861 tccaaactta ttacgcatca gcgaattcac actggagaaa aaccgtatca gtgtattgaa
     1921 tgtgggaaat ccttcagatg gaactctaac ctcgtcatac atcagagaat tcatactgga
     1981 gagaaaccgt acgattgcac tcactgtgga aagtccttca gccaaagcta tcagttagtt
     2041 gcacataaaa gaactcacac tggagaaaag ccctatgaat gtaacgagtg tggaaaagcc
     2101 ttcaatcgaa gcactcagct catcaggcat ctgcaaattc acactgggga gaagccgtac
     2161 aaatgcaatc agtgcaataa agcctttgca aggagctcct accttgtgat gcatcagaga
     2221 actcacactg gtgagaaacc ttttgagtgt agtcagtgtg ggaaagcctt ttcagggagc
     2281 tctaaccttc tttcccatca cagaattcat tctggagaga aaccctatga atgtagtgac
     2341 tgtgggaaat ccttccggca gcaatctcaa cttgtagtgc atcggcggac acatactgga
     2401 gagaaacctt aggagtgcag tcattgtggg aaagctttca tccagaggtc tcccctcatc
     2461 atgcaccaga ggacgcatgt cggtgggaag agctatcagt gtgacgtgta ttaagccagc
     2521 ggttgtgact cattgaacat cagaggacat atcctggaga aaagccctac gaatgcattg
     2581 attgtgggaa agccttcaat gatcgctcaa cccttagtaa acacgagagg acacacactg
     2641 gaggcaaacc ctatgaatgt gaccattgcg agaaagcctt tagccaacgg tgtcaactta
     2701 ctaggcagca gagaattcat actggagaga agccctgtga atgttaacaa atgtggaaaa
     2761 gcttccagtt atgatacttt ccttattcaa catgagaaag ctcatgggca agaaactcta
     2821 tgaataacca agatggagcc gggtgcagtt gccaacactt gtaatcccag cagtttgcga
     2881 ggccgaggca ggtggatcac ttgagcccag gagtttgaaa ccagcctggg taacatggca
     2941 aaatcctgtc tttacaaaaa atacaaaaat tagcctagca tggtggcgca tacctgtagt
     3001 cctagctact caggaggctg aggtgggagg atcacttgag cttgggaggc ggtggttgca
     3061 gtgagctgtg atcatgccat cacaccgctg ccttgtgaga gattgagaca ctctaaataa
     3121 ataataacca agatgggaaa tttccctgcc agaccttgtt tactagaaat caggtggcca
     3181 aaacatgact ctcagagtgg ggcttcatga ccatgtgcat cagaattgcc tggagtgtgc
     3241 actgaaactg tgtattacca agctcactct agccaactaa ataaaaatct ctggcagtaa
     3301 aa
//
