LOCUS       NM_001348156            6133 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 525 (ZNF525), transcript variant
            1, mRNA.
ACCESSION   NM_001348156
VERSION     NM_001348156.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6133)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA790976.1, AK097037.1, BX952742.1, AC010467.9, AC125388.2 and
            BQ028675.1.
            
            On May 17, 2019 this sequence version replaced NM_001348156.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7346977.2632637.1,
                                           SRR7346977.2394901.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000474037.6/ ENSP00000417696.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                DA790976.1         13-29
            18-264              AK097037.1         1-247
            265-592             BX952742.1         96-423
            593-2572            AC010467.9         142322-144301
            2573-5841           AC125388.2         1890-5158
            5842-6133           BQ028675.1         10-301              c
FEATURES             Location/Qualifiers
     source          1..6133
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.42"
     gene            1..6133
                     /gene="ZNF525"
                     /note="zinc finger protein 525"
                     /db_xref="GeneID:170958"
                     /db_xref="HGNC:HGNC:29423"
     exon            1..55
                     /gene="ZNF525"
                     /inference="alignment:Splign:2.1.0"
     exon            56..137
                     /gene="ZNF525"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..1562
                     /gene="ZNF525"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 525 isoform 1"
                     /protein_id="NP_001335085.1"
                     /db_xref="CCDS:CCDS86802.1"
                     /db_xref="GeneID:170958"
                     /db_xref="HGNC:HGNC:29423"
                     /translation="MALPQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNL
                     VSLGISSKCTMKEFSSTAQGNTEVIHTGTLQRHERHHIGDFSFQEIEKDIHNFEFQWQ
                     EDERNGHEAPMTKIKKLMGSTEQYDHRHAGNKPIKYQLGSSFHSHLSELHIFQPKGKI
                     NNQVEKSINDASSVSTAQRISCRPKTHISNNYGDNFLNYSLLTQRQEVRMREKSFQCI
                     ESGKAFNYSSLLRKHQIIHLGEKQYKCDVCDKVFIRKRYLARHRRCHTGEKPYKCNEC
                     GKSFSQMSSLTYHHRLHTGEKPYKCEECDKAFRHNSALQRHRRIHTGEKPHKCNECGK
                     TFSQKSYLACHRSIHTGKKPYECEECDKAFSFKSNLESHRITHTGEKPYKCNDCGKTF
                     SHMSTLTCHRRLHTGEKPYKCEECDEAFRFKSSLERHRRIHNGEKLYKCNECGKTFSQ
                     ELSLTCHCRLHSGEKPCKCGECDKAYSFK"
     exon            138..264
                     /gene="ZNF525"
                     /inference="alignment:Splign:2.1.0"
     exon            265..6133
                     /gene="ZNF525"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6101..6106
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF525"
                     /note="hexamer: AATAAA"
     polyA_site      6133
                     /gene="ZNF525"
                     /note="major polyA site"
ORIGIN      
        1 agacgcgcgc aaacccggaa gcagatcgcg tggagtgaag gtccctcagc ggcgcgattg
       61 acatctaaag actcttggta catgaggaag aaacccggaa aaggaaagca gaggagtcag
      121 ggatggctct tcctcagggt ctattgacat tcagggatgt ggccatagaa ttctctcagg
      181 aggagtggaa atgcctggac cctgctcaga ggactctata cagggacgtg atgctggaga
      241 attataggaa cctggtctcc ctgggtatct cttccaaatg cacaatgaag gagttctcat
      301 caacagcaca aggcaataca gaagtgatcc acacagggac attgcaaaga catgaacgtc
      361 atcacattgg agatttttcc ttccaggaaa ttgagaaaga tattcataac tttgagtttc
      421 agtggcaaga agatgaaaga aatggccatg aagcacccat gacaaaaatc aaaaaattga
      481 tgggtagtac agagcaatat gatcacaggc atgctggaaa caagcctatt aaatatcagc
      541 ttggatcaag ctttcattca catctgtctg aactccacat atttcagccc aaagggaaaa
      601 ttaataatca agtggagaag tctatcaacg atgcttcctc ggtttcaaca gcccaaagaa
      661 tttcttgtag gcccaaaacc catatatcta ataactatgg ggataatttt ctgaattatt
      721 cattactcac acaaagacag gaagtacgca tgagagaaaa atctttccaa tgtattgaga
      781 gtggcaaagc ctttaattat agctcactct taaggaaaca tcagattatt catctaggag
      841 agaaacaata taaatgtgat gtatgtgaca aggtctttat tcggaagcga taccttgcac
      901 gccatcgtag atgtcacact ggtgagaaac cttacaagtg taatgagtgt ggcaagtcct
      961 tcagtcagat gtcatccctt acatatcatc atcgacttca tactggagag aaaccttaca
     1021 aatgtgaaga atgtgacaaa gctttcagac acaattcagc ccttcaaaga cataggagaa
     1081 ttcatactgg agagaaacca cataagtgta atgagtgtgg caagaccttt agtcagaagt
     1141 cataccttgc atgccatcgt agcattcata ctggaaagaa accttacgaa tgtgaagaat
     1201 gtgacaaagc tttcagtttc aaatcaaacc ttgaaagtca taggataact catactggag
     1261 agaaaccata caagtgtaat gattgtggca agaccttcag tcatatgtca acccttacat
     1321 gccatcgtag acttcatact ggagagaaac cttacaagtg tgaagaatgt gatgaagctt
     1381 tccgtttcaa atcaagtctt gaaagacata ggagaattca taatggagag aaactgtaca
     1441 aatgtaatga gtgtggcaag accttcagtc aggagttatc ccttacctgc cattgtagac
     1501 ttcatagtgg agagaaacct tgcaagtgtg gagaatgtga caaggcttac agtttcaaat
     1561 aaaatcttga aatacgtcag aaaattcata ctggagagaa atgttataag tgtaatgatt
     1621 gtggcaagat cttcagtcat acgtcatcca ttgtatacca tcataaattt catagtggag
     1681 agaaacctta caaatgtgaa gaatgtgatg aagctttcag tttcaaatca aaccttgaaa
     1741 gacataggag aattcacact ggtgagaaac cttacaggtg taataggtgt ggcaagacct
     1801 tcagtcatac atcatccctt acatgccatc atagacttca tactggagag aaaccttaca
     1861 aatgtgaaga atgtgatgaa actttcagat acaaatcaaa tcttgaaaga cataggagaa
     1921 ttcataatgg agagaaaccg tacaagtgta atgagtgtgg caagaccttc agtcagaagt
     1981 catgccttac acgccatcat agacttcata ctggaaataa atcttataag tgtaatgagt
     2041 gtggcaagac cttcagtaag gagttaacac atgccatcat agacgtcata ctggagagaa
     2101 accttagaag tgcaatgagt gtggcaaaac ctttcatagg cagtcagcgc ttatttacca
     2161 tcaagcaatc catggcagag ggaaacttta caaatgtaat gattgtcacc acgtcttcag
     2221 taatgctaca actattgcaa atcattggag aatccataat aaagagagac cttacaagtg
     2281 tgataaatgt gacaaatttt tcagacatcg ttcatacctt gcagttcacg ggcgaactca
     2341 tgctggagag aaaccttaca aatgtgaaga atgtgataaa gctttcagat tcaaatcaaa
     2401 ccttgaaagt cataggagaa ttcatactag agagaaacct tacaagtgta atgagtgtgg
     2461 taagatgttc agtcaaaatt cggcccttgt aattcataag gcaattcata ctggagagaa
     2521 accttacaag tgtaatgaat gtggcaaggt ttttaatcgc aaagcaaagc ttgcatgtca
     2581 tcatagactt catactggag agaacgcttg caagtgtaat aaatgtggcg aggtttttaa
     2641 tcaacaagca caccttgcac gtcatcatag aactcatact ggagagaaac attacaagtg
     2701 taatgagtgt ggcaagacct actctcacaa ttcagtcctt gtaattcata agacaattca
     2761 cactggggag aaaccttaca agtgtaatga gtgtggcaaa accttccatc acaattcagt
     2821 ccttgtaatt cataaaacaa ttcatactgg agagaaacaa gcgtaatgaa tgtggcgagg
     2881 ttttcaatca acaagcacac gttgcacgtc atcatagaat tcatactgga gagaaacctt
     2941 agaaatgtga agaatgtgac aaagtttaca gtcgcaaatc aaacctcgaa agacaggaga
     3001 attcatactg gagagaaacc ataaaaatgt aagagttttt gacaaggctt tcggacgtga
     3061 ttcacacctg gcacaacatc ccagagttca cactggagag aaaccttaca agtgtaatga
     3121 gtgtgtcaaa gcctttagtg ggcagtcaac acttattcac catcaggcaa tccgtagtgt
     3181 agggaaactt gactaacgta atgattctca caacgtcttc agtaatgcta caaccattgt
     3241 aaatcactgg agaagccata atgaagagag atcttacaaa tgtaataatt gtggcaaatt
     3301 tttcagacat cgttcataca ttgccgttca ttggcgaact catgctggag agaaatctta
     3361 caatgtcatg attgtggcaa ggtcttcagt caagcttcat cttttgcaaa acaggagaat
     3421 tcatacagga gagaaacctc acaagtgtga tgatcgtggc aaagccttta cttcacattc
     3481 tcacctcatt agacatcaga gaatccatac tggacagaaa tcttacaaat gtcatcagtg
     3541 tggcaaggtc ttcagtccga cttcactcct tgcagaatat cagaaaattc atttttcagg
     3601 taattgttcc caatgcaatg aatatagcaa accatcaagc attgattgac attagagtca
     3661 gttcagcatt gacttgagtt tgagttgact taacattgag ttcaagcctt aattgacatt
     3721 aaagtgttta tgttaagagg actgggctgt gtggcatggc tcacgcctgt aatcccagca
     3781 ctttggtagg ccaaggtggg taaatcactt gaggtcagga gtttgagatc agcctggaca
     3841 acagacctga gccacttttc ccagcctgtt ttttgtttct ttaacaaaaa ctgataggga
     3901 tttttatggg tatcgtattg aatctagatt acattgggtt atataatcat ttaacatatt
     3961 aatttttcca aaccatcaat atgggttgtg tctctatata tgtttttaat cattttgatc
     4021 aatttttgtt gatttcaagg tacaaacgtc tcaccttttt acgtttattc ctaagtattt
     4081 cttattttaa gttctccagc aaatggaagt gtgttaaaat tttcttttaa aattgtttat
     4141 tattaaaata tggaaattca actaattttt ggtgctgata ctgtattgtg caaatccact
     4201 gaatatgttt gttagttcca gtactatttt ggttgagtct gtgattttct acacagaagg
     4261 tcatgtcgtc tacaaacaaa tgtaatttta cttctttctt tctgatttgg atgagtttga
     4321 tttcttttgc tatttaattg ctctggctag gacaggcagt attgattgaa tagaaggggt
     4381 gagagcattc ttgcatcatg tgagatcgta caggaaagca ttccattttc cctgcttggt
     4441 tatttactca tttgtcattt catggatgtt ctttctattg ttgaggtaaa tttccttttc
     4501 tattttgttt aggatttcta tgatgactgg attttgaatt ttgtggaacg ctttttctcc
     4561 atctactaag gtgatgtggt tttaatcttt cattctgttc tagtggtata taacattgat
     4621 ttgcttgaat atgttgaacc atccttgcat cccagaaata actggcactt gaatatctac
     4681 atttttttaa tatcctcttg aatacagttt tctaggacaa gggatcttca agaagttctg
     4741 gaaaaataca tattatgaga aaattgtgca tgaatttcac aatttttgca ccaaaataaa
     4801 ctagtgctag tctgttataa catgtctgaa caggctctag tttgatgccc tcaaaaggat
     4861 aagacatgag tataaaaaga gactccatca aagcaatata aattctgatg aaatttaaac
     4921 aagaagaaac attaaattta tgatgagacc agatgcagtg gctcaggcct gtaatcccag
     4981 cattttcaga ggctgagaca ggtgggccac atgagcccag gtattcaaga ccagcctggg
     5041 aaacgtgggg aaatcccctt ttctacaaaa aatacaaaaa ttagctgggc atggtggcac
     5101 atgcctgccg tctcagttat tgtgaagtct gtgcagggag gatggcatga acctgggagg
     5161 tcaagattgc agtgagctat gatcatgcca ctgcactcca gcatgggtga tggagagaga
     5221 tactgtctta aaaaaagaat acttgtggta acgtttgggt agaggaataa tgaaatcatt
     5281 gatgctttat aaaaaggtta tggggacaat gcccaaaaga aataaacagt ttgtaaacgg
     5341 ataacttatt ttgagttagg gcaagacaat gttgacagtg atgcatgaag cagcaggcag
     5401 accttccaca tcatttttac agaaaaaaaa attaatcttg ttcatgctgc aatgaagagg
     5461 actgacagca aacagcagaa acatagtcag aatttagaga acagcctggt taacatggtg
     5521 aaacaccatc tctagtaaaa atacaaaaat tagctcagca tggtggcatg cgcctgtaat
     5581 cccagctact caggaggctg aggcagggga atctcttgaa cccaggaggt ggaggatgca
     5641 gtgaactgag atggcaacat tacactctag cctgagcaac aagagcaaaa ctccatctca
     5701 aaaaaaaaaa aattgtcaag ttccttctct tccattcttt gccatcgtgg tgtgtgcttg
     5761 actctgcttc ttgccacatc ttctcagaag actttcagga ttaagcgatt cctggccaag
     5821 aaacaaaagc aaaaccatcc cactcccctg tggattcaga tcaaaactgg taataaaatc
     5881 aggtacgact ccaaaaggag acattggaga agaaccaagc tgggtctata aggaattgca
     5941 tgtgagatgg cacacatatt tatgctgtct gagcatcaca atcacgttac catatcaagc
     6001 tgaaaatgtc accactatct ggacagttgg acatgtttta ttgggaatat gttttttctc
     6061 tgtaaatttg ttataaacgc attggttggc tgtgttcagt aataaacgtg agacttttca
     6121 tttcaaaaca aaa
//
