LOCUS       NM_001258280            3353 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 501 (ZNF501), transcript variant
            2, mRNA.
ACCESSION   NM_001258280
VERSION     NM_001258280.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3353)
  AUTHORS   Serebrenik,Y.V., Hellerschmied,D., Toure,M., Lopez-Giraldez,F.,
            Brookner,D. and Crews,C.M.
  TITLE     Targeted protein unfolding uncovers a Golgi-specific
            transcriptional stress response
  JOURNAL   Mol Biol Cell 29 (11), 1284-1298 (2018)
   PUBMED   29851555
REFERENCE   2  (bases 1 to 3353)
  AUTHORS   Yin,Y., Morgunova,E., Jolma,A., Kaasinen,E., Sahu,B.,
            Khund-Sayeed,S., Das,P.K., Kivioja,T., Dave,K., Zhong,F.,
            Nitta,K.R., Taipale,M., Popov,A., Ginno,P.A., Domcke,S., Yan,J.,
            Schubeler,D., Vinson,C. and Taipale,J.
  TITLE     Impact of cytosine methylation on DNA binding specificities of
            human transcription factors
  JOURNAL   Science 356 (6337) (2017)
   PUBMED   28473536
REFERENCE   3  (bases 1 to 3353)
  AUTHORS   Kipper,S., Hamad,S., Caly,L., Avrahami,D., Bacharach,E., Jans,D.A.,
            Gerber,D. and Bajorek,M.
  TITLE     New host factors important for respiratory syncytial virus (RSV)
            replication revealed by a novel microfluidics screen for
            interactors of matrix (M) protein
  JOURNAL   Mol Cell Proteomics 14 (3), 532-543 (2015)
   PUBMED   25556234
REFERENCE   4  (bases 1 to 3353)
  AUTHORS   Lichter,P., Bray,P., Ried,T., Dawid,I.B. and Ward,D.C.
  TITLE     Clustering of C2-H2 zinc finger motif sequences within telomeric
            and fragile site regions of human chromosomes
  JOURNAL   Genomics 13 (4), 999-1007 (1992)
   PUBMED   1505991
REFERENCE   5  (bases 1 to 3353)
  AUTHORS   Bray,P., Lichter,P., Thiesen,H.J., Ward,D.C. and Dawid,I.B.
  TITLE     Characterization and mapping of human genes encoding zinc finger
            proteins
  JOURNAL   Proc Natl Acad Sci U S A 88 (21), 9563-9567 (1991)
   PUBMED   1946370
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB086337.1 and BC013762.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001258280.1.
            
            Transcript Variant: This variant (2) contains an alternate segment
            in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the
            same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.202976.1,
                                           SRR1803612.277378.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000620116.5/ ENSP00000482632.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-551               DB086337.1         5-555
            552-2124            BC013762.1         263-1835
            2125-3353           BC013762.1         1837-3065
FEATURES             Location/Qualifiers
     source          1..3353
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.31"
     gene            1..3353
                     /gene="ZNF501"
                     /gene_synonym="ZNF; ZNF52"
                     /note="zinc finger protein 501"
                     /db_xref="GeneID:115560"
                     /db_xref="HGNC:HGNC:23717"
     exon            1..381
                     /gene="ZNF501"
                     /gene_synonym="ZNF; ZNF52"
                     /inference="alignment:Splign:2.1.0"
     exon            382..466
                     /gene="ZNF501"
                     /gene_synonym="ZNF; ZNF52"
                     /inference="alignment:Splign:2.1.0"
     exon            467..3353
                     /gene="ZNF501"
                     /gene_synonym="ZNF; ZNF52"
                     /inference="alignment:Splign:2.1.0"
     CDS             692..1507
                     /gene="ZNF501"
                     /gene_synonym="ZNF; ZNF52"
                     /note="zinc finger protein 52"
                     /codon_start=1
                     /product="zinc finger protein 501"
                     /protein_id="NP_001245209.1"
                     /db_xref="CCDS:CCDS2720.2"
                     /db_xref="GeneID:115560"
                     /db_xref="HGNC:HGNC:23717"
                     /translation="MNSSQISLRMKHGRVNMQKKPSKCSECGKFFTQRSSLTQHQRIH
                     RGEKPYVCSECGSCFRKQSNLTQHLRIHTGEKPYKCNECEKAFQTKAILVQHLRIHTG
                     EKPYKCNECGKAFCQSPSLIKHQRIHTGEKPYKCTECGKAFSQSICLTRHQRSHSGDK
                     PFKCNECGKAFNQSACLMQHQRIHSGEKPYTCTECGKAFTQNSSLVEHERTHTGEKLY
                     KCSECEKTFRKQAHLSEHYRIHTGEKPYECVGCGKSFRHSSALLRHQRLHAGE"
     regulatory      1769..1774
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF501"
                     /gene_synonym="ZNF; ZNF52"
                     /note="hexamer: AATAAA"
     polyA_site      1796
                     /gene="ZNF501"
                     /gene_synonym="ZNF; ZNF52"
     regulatory      3330..3335
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF501"
                     /gene_synonym="ZNF; ZNF52"
                     /note="hexamer: AATAAA"
     polyA_site      3353
                     /gene="ZNF501"
                     /gene_synonym="ZNF; ZNF52"
                     /note="major polyA site"
ORIGIN      
        1 actcctttcc gcagggcagc acccagggac ctgagtgttg caaggtgcga gaggggagcg
       61 ccgcggggag cgccgcggga agcgcatggt gagcggtttc tgctgtgccc ggctgccgcg
      121 ggtcgattcc agctcctccc tcgggaagca gggcgttttt cttcctggag ggcctgtgga
      181 gcggaggccc gaggcctagg gcaaacttgc catgaagaaa ggagaggctg ttcgagagcc
      241 ctaggctggg agtcggagga cctgggttcg atttatacat acttaagcat gtcagtgaac
      301 ttctgggcac tttagttttc tgatttccag aagtaaatac tgtttcctgc cttgccgttt
      361 cccaaagttg tgcgggttga atgcctcaaa ttcctgcctt tcctcaagag aagagccccc
      421 aggagaaaag ccagtattgc ttgtgctcct aacaacctgt ctcttgagag gctgatcatc
      481 aggggttcac tttcagagaa gttgagaatg caggctgaac aaggaagagg aaggggaatc
      541 ctgcagggat gaatgagagg acagcaatgc atgtgtgatg tgtgtgagca cacacacaca
      601 gtaacctttc ctaggagaac tgtattactc taatgataat cacctttgag gaaaaaaaac
      661 ttgtaagtat gaatttggtg ttacaagcag catgaattcc agccaaatat cactcagaat
      721 gaaacatggg agagttaaca tgcagaagaa accttcaaag tgtagtgaat gtgggaagtt
      781 ctttactcag agatcatctc ttacccagca ccagaggatt cacagaggag agaagcccta
      841 tgtgtgcagt gaatgtggaa gttgtttccg taaacagtca aatcttactc aacatctgag
      901 aattcatacc ggagagaaac cttataaatg taatgaatgt gagaaagcct ttcaaacaaa
      961 agcaattctt gttcagcatc tgagaattca tactggagag aaaccctata aatgcaatga
     1021 atgtggaaaa gccttttgtc agagcccatc ccttattaaa caccagcgaa ttcatactgg
     1081 agagaaacca tataaatgta cagaatgtgg caaagccttc agtcagagca tatgccttac
     1141 tcgtcatcag agaagtcatt ctggagataa accttttaag tgtaatgaat gtgggaaagc
     1201 ctttaatcag agtgcatgtc tcatgcagca tcagagaatt cattcaggag agaagcccta
     1261 cacatgcact gaatgtggta aagccttcac tcagaactct tcccttgttg aacatgaaag
     1321 gactcacact ggagagaaac tttataagtg tagtgagtgt gaaaaaactt tccgcaaaca
     1381 agcacacctt agtgagcatt acagaattca tactggagaa aaaccttatg agtgtgttgg
     1441 atgtgggaaa tcctttaggc acagttcagc acttcttcga catcagaggc ttcatgctgg
     1501 agagtaaaat ttggaatata atgagtatgg gaagatttgt atggaagcac cttttttttc
     1561 tcctaaattc ctaggaatgt aagactcaat ctgtagctag tatgaatatt ttgtattttg
     1621 aacaagaaat gttgtgtcct aatgtgtcct agtctggagt ttgatgcctt atctgctgct
     1681 cagtgggtgt aaccttatcc cttctgagcc tcagtttccc cattcccccc aatagaaaaa
     1741 tggggatatt tcctagggtt gtcctgagaa taaaatgagt tctgtgtgac agttaactgc
     1801 cattaattaa ttagccgttc taaaagttta tttacaatat caaaatctga caagtaaatc
     1861 agcattgttg tttggttctc ataatgtatt gtttcttaag aacattttgt aattgggcta
     1921 tgattttatg atctacagac gtctatttaa actataatgt cttggtttaa ataggataat
     1981 acaatctaag actggtttgt ccttgagaaa tttcagattt aatcagagaa aaatgtactg
     2041 attgggattt gagtggacat tgtggggtgt atttctggat accctcaaga tcttcattta
     2101 aattttgata ctttctatta ctagatctaa tttgatttta agctctaagt ttcacttttc
     2161 cattaaacgg aaagcctccc tgacattaac tgaataaaac ctcatgttgt gggacttctg
     2221 tgtgtgttta gggttggcag caggtgatta ggagaaggca tatgacagta gagaggactg
     2281 gaatatagag gagaatataa gcatgtagat gaggatgtgg ctgtatttgt tttgagttct
     2341 aggagcacag caccaaatgt ggtctcttaa gggaagatga gggtagaaga tgttaagatc
     2401 ccaggttcca gcaactgatg ccactgacta acaactagcc acttgtcaga ggaaggagag
     2461 aacagtgtct tggggatgct gatgggttgg agtgcctaat ggctcattaa aagccatgaa
     2521 aaagcaaaga aatcaaagaa tacttttgat ggagctttag gctatgctaa gccttttaat
     2581 gtaaacaagc acctctaacg ctaaaagcac ccttgcaaga aaggtaggag ttactattca
     2641 catcctagag tcaaggaaaa agagaagatg tttgacttgc tcaaagtcaa gcaggtaatg
     2701 tcagaattga atctcaaatc tatatcttta tagatttgca gttctggttt atataatacc
     2761 aaagtcacat acaggtaatt tcccaccatt gaaccttcct gttggtgtga gatgccaaat
     2821 ctgtgaaaac cagacacagg tggccaggtg ggtgtcgaac tcctgacctc aagtgatccg
     2881 cctgcctcag cctcccaaag tgctgggatt acaggtgtga gtcaccacat ctggtcggat
     2941 tttaactatt ctaataggta tgtagtggta ttaattgttt taatctgcag ttcaccaata
     3001 atatatgaat ttagcatctt ttcatatgtt tgccatctgt atagctttgg tgaggtatct
     3061 gttagaggtt ttgcccattt ttaattggat tgctcatttt cttattgttg aattttaagt
     3121 gttccttgta tattttgtat aacagacctt tatcagatag gtcttttgca aatattttcc
     3181 tcccaggctg tggcttattt tctcaatcct tgattccttc tctttacttt ttttttcttt
     3241 tttctttttt taaagaaatg gtagcataat atacacagtt gtccattttt taaagactaa
     3301 accatctcac agattgttct gtatcagtaa ataaagatct ttcccccacc ctt
//
