LOCUS       NM_001355444            2128 bp    mRNA    linear   PRI 29-OCT-2022
DEFINITION  Homo sapiens zinc finger protein 487 (ZNF487), transcript variant
            1, mRNA.
ACCESSION   NM_001355444 NR_026693 XM_001714430 XM_926224 XM_936711
VERSION     NM_001355444.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2128)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL450326.30.
            
            On Apr 22, 2020 this sequence version replaced NM_001355444.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK302442.1, SRR1803612.5900.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968189, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000437590.4/
                                                ENSP00000392335.2
            RefSeq Select criteria           :: based on manual assertion,
                                                expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-152               AL450326.30        34676-34827
            153-279             AL450326.30        73286-73412
            280-375             AL450326.30        73672-73767
            376-2128            AL450326.30        78994-80746
FEATURES             Location/Qualifiers
     source          1..2128
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q11.21"
     gene            1..2128
                     /gene="ZNF487"
                     /gene_synonym="KRBO1; ZNF487P"
                     /note="zinc finger protein 487"
                     /db_xref="GeneID:642819"
                     /db_xref="HGNC:HGNC:23488"
     exon            1..152
                     /gene="ZNF487"
                     /gene_synonym="KRBO1; ZNF487P"
                     /inference="alignment:Splign:2.1.0"
     exon            153..279
                     /gene="ZNF487"
                     /gene_synonym="KRBO1; ZNF487P"
                     /inference="alignment:Splign:2.1.0"
     CDS             246..869
                     /gene="ZNF487"
                     /gene_synonym="KRBO1; ZNF487P"
                     /note="isoform 1 is encoded by transcript variant 1; KRAB
                     domain only 1; zinc finger protein 487, pseudogene; KRAB
                     domain only protein 1; putative zinc finger protein 487"
                     /codon_start=1
                     /product="putative zinc finger protein 487 isoform 1"
                     /protein_id="NP_001342373.2"
                     /db_xref="CCDS:CCDS86084.2"
                     /db_xref="GeneID:642819"
                     /db_xref="HGNC:HGNC:23488"
                     /translation="MLENYSLLLSVGYCITKPEVVCKLEHGQVLWILEEESPSQSHLD
                     CCIDDDLMEKRQENQDQHLQKVDFVNNKTLTMDRNGVLGKTFSLDTNPILSRKIRGNC
                     DSSGMNLNNISELIISNRSSFVRNPAECNVRGKFLLCMKRENPYARGKPLEYDGNGKA
                     VSQNEDLFRHQYIQTLKQCFEYNQCGKAFHEEAACSTHKRVCSWETL"
     exon            280..375
                     /gene="ZNF487"
                     /gene_synonym="KRBO1; ZNF487P"
                     /inference="alignment:Splign:2.1.0"
     exon            376..2128
                     /gene="ZNF487"
                     /gene_synonym="KRBO1; ZNF487P"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2103..2108
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF487"
                     /gene_synonym="KRBO1; ZNF487P"
                     /note="hexamer: AATAAA"
     polyA_site      2128
                     /gene="ZNF487"
                     /gene_synonym="KRBO1; ZNF487P"
                     /note="major polyA site"
ORIGIN      
        1 agggagcgct gcggcagttt ccatggtgag atggtcaaca agcctgtaag ttcctcagct
       61 acgactacca ggtacctcgg gttcctccct cctccgagag accgccgagg tgcgggctgt
      121 gagaggggga gcgtggagcc tccgaggccg agggatcagt gtccttcagt gatgtggctg
      181 tgggcttcac ccaggaggag tggcagcatc tggactctgc tcagaggacc ccgtacagag
      241 acatgatgct ggagaactac agcctcctcc tctcagtggg atattgcatt accaaaccag
      301 aggtggtttg caagttggag catggacagg tgctgtggat attagaggaa gagtccccaa
      361 gtcagagcca cctagactgc tgcatagatg atgacctgat ggagaagaga caggaaaatc
      421 aagaccagca tttgcagaaa gttgattttg tcaacaataa aacactgact atggacagaa
      481 atggtgtatt aggaaaaaca ttttctcttg acacaaaccc cattctatca agaaaaatac
      541 gtggcaactg tgactcatct ggaatgaatt tgaataatat ttcagaatta attattagta
      601 atagaagctc ctttgtaagg aaccctgctg agtgtaatgt acgtgggaaa tttctcctct
      661 gtatgaagcg tgagaatcct tatgccagag ggaaaccttt ggaatatgat ggaaatggga
      721 aagccgtctc tcagaatgag gacttattta ggcatcagta tattcaaact cttaagcagt
      781 gttttgaata caatcagtgt gggaaggctt ttcatgaaga ggcagcctgc agtacccata
      841 agagagtgtg ctcatgggag accctgtgaa tataatgaac atgtgagagc cttttccgat
      901 agaccaatat tcattgttca tcagagaact cacataagga agagtcacca tgaattcaat
      961 gaatgtgaga ggaggtctgg tgagaggcca cctgtaaata aacaccacag ggttatggag
     1021 atgaaatact atgagtgtaa tgcgagtgag aatagttttg gcaagaaatc actcctcatt
     1081 ctacaaagtt acagaggaga gaaaacttga ctgtagtaga catttggaag tattctgcaa
     1141 gaagccaaat ttcactcaac atcaagaaac acatatagga aagaatgcct ataaaattaa
     1201 tcagtatgct agtacatttt gctgtaagcc aaagcattct gtatatcaga aaacagatac
     1261 agaagaaaaa ctctatgaat gtagtgaatg tgggaaaacc ttcagccata aatcctcttt
     1321 tatcctacag cagaggatac acagaggaga gaaaccctat gaatgcactg aatgtgggaa
     1381 aacttttgga tataggtcat gccttgcagt acatcaaaga acacacacgg gacaaaacct
     1441 atgaatgtaa tgaatgtgga aaaaacttct gtgagaagtc aaatcttcat gtacatcaga
     1501 gaacacacac aggagagaaa ccctatggat gtaatgaatg tcagaaagcc tttggtgata
     1561 ggtcagctct aaaagtacat cagagaatac atactggcga gaaaccctat gagtgtaagg
     1621 aatgtgggaa aactttctcc cagaagccaa acttcattaa tcatcagtga actcacacag
     1681 gagagagacc ctttgaatgc aatgaatgtc aaaaatcctt ctctgtgaag tcaaaactta
     1741 gagaacatca gagaattcac acaggggaga aaccctatga atgtaatgaa tgtgagaaaa
     1801 tgttctacca caagtcatcc ctcacagtac atcagagaac ccacacagga gagaaaccct
     1861 atgcatgtag tgaatgtggg aaaaccttct accagaagtc atccctcaca acacatcaga
     1921 gaacacacac aagggagcaa ccctatgaat ataatgaaag cttttaccag aatcccaact
     1981 tcactaaatg tcagagagac aacatagagg aaacccttgt caacatcctg aaggctcaga
     2041 aaccttcacc ttcttggact cgttccatag cagaaacaac ccaggttggg gtgagaacac
     2101 ccaataaaga tgagaaatct tttgccta
//
