LOCUS       NM_207317               1929 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 474 (ZNF474), mRNA.
ACCESSION   NM_207317
VERSION     NM_207317.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1929)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB058648.1, AY461732.1 and AK290985.1.
            
            On Nov 24, 2018 this sequence version replaced NM_207317.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY461732.1, SRR5189667.219206.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968189, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000296600.5/ ENSP00000296600.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-503               DB058648.1         34-536
            504-1786            AY461732.1         530-1812
            1787-1875           AK290985.1         1750-1838
            1876-1929           AY461732.1         1902-1955
FEATURES             Location/Qualifiers
     source          1..1929
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q23.2"
     gene            1..1929
                     /gene="ZNF474"
                     /note="zinc finger protein 474"
                     /db_xref="GeneID:133923"
                     /db_xref="HGNC:HGNC:23245"
     exon            1..138
                     /gene="ZNF474"
                     /inference="alignment:Splign:2.1.0"
     exon            139..1929
                     /gene="ZNF474"
                     /inference="alignment:Splign:2.1.0"
     CDS             351..1445
                     /gene="ZNF474"
                     /note="4933409D10Rik; TSZFP; testis-specific zinc finger
                     protein"
                     /codon_start=1
                     /product="zinc finger protein 474"
                     /protein_id="NP_997200.1"
                     /db_xref="CCDS:CCDS4130.1"
                     /db_xref="GeneID:133923"
                     /db_xref="HGNC:HGNC:23245"
                     /translation="MERGKKKRISNKLQQTFHHSKEPTFLINQAGLLSSDSYSSLSPE
                     TESVNPGENIKTDTQKKRPGTVILSKLSSRRIISESQLSPPVIPARRPGFRVCYICGR
                     EFGSQSIAIHEPQCLQKWHIENSKLPKHLRRPEPSKPQSLSSSGSYSLQATNEAAFQS
                     AQAQLLPCESCGRTFLPDHLLVHHRSCKPKGEGPRAPHSNSSDHLTGLKKACSGTPAR
                     PRTVICYICGKEFGTLSLPIHEPKCLEKWKMENDRLPVELHQPLPQKPQPLPNAQSSQ
                     AGPNQAQLVFCPHCSRIFTSDRLLVHQRSCKTHPYGPKYQNLNLGSKGGLKEYTNSKQ
                     QRNRAAPSVTDKVIHATQDALGEPGGALCL"
     regulatory      1902..1907
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF474"
                     /note="hexamer: ATTAAA"
     polyA_site      1929
                     /gene="ZNF474"
                     /note="major polyA site"
ORIGIN      
        1 agcctcaaaa actcacacca gctcctgcaa ggaatgtgaa tcttggagct cccagctatt
       61 ctgttcctgt ttctgtcagc tccttccctg aaaactcaga ggtgctcagc atgccatgct
      121 aaaaggcaaa ataaaaagat cttggagaca tctcagcttt aatgaggact ttccaacatt
      181 ccagactgcc gtcctgcaat gaagctctga gtcacggtct gtgaggctaa ggtactggca
      241 acggtgtgaa ccccaggaca actaacctca ctaaccttca ctctaagcag aagcccaaag
      301 tgagtctggc ctgaaatcag agcaagcact acagaaagac atctttgtta atggaaagag
      361 gaaagaagaa aagaatttcc aataagttac aacaaacttt tcaccattct aaagaaccca
      421 ctttccttat caaccaagct gggcttctct ctagtgactc ctattctagc ctttccccag
      481 aaacagagag tgttaatcct ggtgaaaata taaagacaga cactcagaaa aagagacctg
      541 ggactgtgat actatcaaaa ctgtcaagta gaagaattat atcggaaagc cagcttagcc
      601 cccctgtgat cccggcccgc aggcctggat tccgggtatg ctatatctgt ggccgagaat
      661 ttgggtccca gtcaattgcc attcatgaac cccagtgctt gcagaagtgg catattgaaa
      721 acagcaagtt gcccaagcat ttgaggaggc cagaaccctc caaaccacag tctctcagca
      781 gcagtgggtc ctacagtctt caggcaacta acgaggctgc atttcagagt gcccaggctc
      841 agctgctgcc ctgtgaatcc tgtggccgca cattcttgcc agatcatctt cttgttcatc
      901 acagaagctg caagccaaag ggtgagggtc ccagagcacc acactcaaac agttctgatc
      961 atcttactgg cctcaagaaa gcttgtagtg gaaccccagc ccgaccaagg actgttatct
     1021 gctacatatg tggtaaggaa tttggcaccc tgtcccttcc tattcatgag cccaaatgcc
     1081 tggaaaagtg gaaaatggaa aatgaccggc tccctgtgga gctccaccag ccactcccac
     1141 agaagcctca gccccttccg aatgcacagt ccagccaagc gggaccaaat caagctcagc
     1201 ttgtgttctg cccacattgt agccgaatct ttacctcaga ccgcctcctg gtacaccaga
     1261 gaagttgtaa aactcatcct tatgggccaa aatatcagaa tttgaattta gggagtaaag
     1321 gaggcctaaa agagtacact aattccaagc agcaaaggaa cagggcagca cccagtgtaa
     1381 ctgataaggt aattcatgcc acacaagacg cattaggtga acctggtggt gccctctgcc
     1441 tgtaggggaa caagagaaaa ctatccccag aatcagccac ctcagcccct agtatttttt
     1501 ctatcaatgc cttgtatcag cctcaaagca gcctgttcaa gttaactccc tgttgaactc
     1561 cagggcctat acctctcttg gctgaataga tataagaaca tccttgcctg atgggttcat
     1621 attcctcttc aattctgctg tctaaaagaa gaagagatgg acttctttct tccctgatcc
     1681 ctgatacaaa taatccctgg gagagacagt aatttgaaaa tgagtcatta atgctgtgtc
     1741 tacattacag agatataatt cccattccaa cagccaatat ttattgtcgg tttattttag
     1801 tcatctacct taggaattca tttttggcaa tgctgggtta tgctgagttt atcttactaa
     1861 aatagaatct gtgtcaaaaa cccccaatga ctttagcaac aattaaacac tgaagcactt
     1921 gcaaaaata
//
