LOCUS       NM_152355               4448 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 441 (ZNF441), mRNA.
ACCESSION   NM_152355
VERSION     NM_152355.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4448)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB250168.1, AC008543.9 and BX649086.1.
            
            On Nov 23, 2018 this sequence version replaced NM_152355.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            transcript and genomic sequence to make the sequence consistent
            with the reference genome assembly. The genomic coordinates used
            for the transcript record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DB250168.1, SRR1803617.39867.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000357901.5/ ENSP00000350576.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-494               DB250168.1         1-494
            495-2811            AC008543.9         156640-158956
            2812-4448           BX649086.1         1954-3590
FEATURES             Location/Qualifiers
     source          1..4448
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.2"
     gene            1..4448
                     /gene="ZNF441"
                     /note="zinc finger protein 441"
                     /db_xref="GeneID:126068"
                     /db_xref="HGNC:HGNC:20875"
     exon            1..197
                     /gene="ZNF441"
                     /inference="alignment:Splign:2.1.0"
     CDS             195..2276
                     /gene="ZNF441"
                     /codon_start=1
                     /product="zinc finger protein 441"
                     /protein_id="NP_689568.2"
                     /db_xref="CCDS:CCDS12266.2"
                     /db_xref="GeneID:126068"
                     /db_xref="HGNC:HGNC:20875"
                     /translation="MDSVAFEDVAINFTCEEWALLGPSQKSLYRDVMQETIRNLDCIG
                     MIWQNHDIEEDQYKDLRRNLRCHMVERACEIKDNSQCGGPFTQTQDSIVNEKIPGVDP
                     WESSECTDVLMGRSSLNCYVRVDSEHKPCEYQEYGEKPYTHTQCGTAFSYQPCFQIHE
                     RPQHGKKLYDCKECASFSSLENLQRHMAAHHGDGPRICKLCGNAFIWPSLFHMLRRTH
                     TEEKPYEYEQCSTAFPAYSSTLRHERTHSGEKPYQCKQCGKAFSCSCYTQLYERTHTG
                     EQSYECKQCGKAFYHLGSFQRHMIVHTGDGPHKCKICGKGFLSPSSVRRHKRTHTGEK
                     PYECKYCGKAFSDCTGFRRHMITHTGDGPHKCKVCGKAFDSPSLCRRHETTHTGEKPY
                     KCECGKAFSDFYYFRNHETTHTGEKPYKCKQCGKAFICCTYLQIHERIHTGERPYKCK
                     QCGKAFRSSNYIRVHEKTHTGEKPYECKQCGKALSHLKSFQRHMIMHTGDGPHKCKIC
                     GKSFDSPSSFRRHERIHTGERPYKCKLCGKGFRSSSYIQLHERTHTGEKPYGCQQCGK
                     ALSDLSSFRRHMITHTGNGPHKCKICGKGFDYPSSVQRHERTHTGEKPYECKECGKAF
                     SHSSYLRIHERVHTGEKPYKCKECGKPFHCPSAFHKHERTHSMEKPYKCKECGEAFHC
                     ISSFHKHEMTH"
     exon            198..324
                     /gene="ZNF441"
                     /inference="alignment:Splign:2.1.0"
     exon            325..388
                     /gene="ZNF441"
                     /inference="alignment:Splign:2.1.0"
     exon            389..4448
                     /gene="ZNF441"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4424..4429
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF441"
                     /note="hexamer: AATATA"
     polyA_site      4448
                     /gene="ZNF441"
                     /note="major polyA site"
ORIGIN      
        1 gtcaatcagg cgcactgacc ggaggagggt gcaaggttca aagagcccgc cgagtcttct
       61 ccacgcccct gcactgggct ccgggttctg tcactgagag acgccctgga acgtctgtgg
      121 cagcttctgt ctcgctggga cccgcactga cagcgggagg cagagggagg aacctggacg
      181 ccggaagccg ggaaatggac tcagtggcat ttgaggatgt ggctataaac ttcacctgtg
      241 aggagtgggc tttgctgggt ccatcacaga agagtctcta cagagatgtg atgcaggaaa
      301 ccatcagaaa cctggactgt ataggaatga tatggcaaaa tcatgatata gaagaagatc
      361 agtacaaaga tctcagaaga aatctaagat gtcatatggt agagagagcc tgtgaaatta
      421 aagataatag tcaatgtgga ggacccttta cccagactca agacagtatt gtgaacgaga
      481 aaatacctgg agtagatcca tgggaaagca gtgagtgtac agacgtcctc atgggtcgtt
      541 catctcttaa ttgctacgtt agagttgaca gtgaacacaa accatgtgag tatcaagaat
      601 atggagagaa gccatataca catacacaat gtgggacagc tttcagttat cagccctgct
      661 ttcaaataca tgaaagacct cagcatggaa agaaactcta tgattgtaag gaatgtgcaa
      721 gcttcagttc tcttgaaaac cttcaaagac acatggcagc acaccatgga gatggacctc
      781 gtatatgtaa gttgtgtgga aacgccttta tttggcctag tttatttcat atgcttagaa
      841 gaactcacac tgaagagaaa ccatatgaat atgagcagtg ttctacagcg tttcctgctt
      901 atagttccac tctaagacat gaaagaacac acagtggaga gaaaccctat caatgtaaac
      961 aatgtgggaa agccttcagt tgttcctgtt acactcaact atatgaaagg actcacactg
     1021 gagaacaatc ctatgaatgt aagcaatgtg ggaaagcatt ttatcatctt ggaagctttc
     1081 aaagacacat gatagtgcac actggagatg ggcctcataa atgtaagata tgtggaaaag
     1141 gctttctttc tcccagttca gttcgaagac ataaaagaac tcacactgga gagaaaccgt
     1201 atgaatgtaa gtattgtggg aaagcattct ctgattgcac aggttttcga agacacatga
     1261 taacgcacac tggagatgga cctcataaat gcaaggtatg tgggaaagcc tttgattctc
     1321 ccagtttatg tcgaaggcat gaaacaactc atactgggga gaaaccctat aaatgtgaat
     1381 gtgggaaagc ctttagtgat ttctattact ttcgaaatca tgaaactact cacactggag
     1441 agaagccata taaatgtaaa caatgtggaa aagccttcat ttgttgcact taccttcaaa
     1501 tacatgaaag aattcacact ggggagagac cctataaatg taaacaatgc ggaaaagcct
     1561 tcaggtcttc caattacatt cgagtacatg aaaagactca cactggagaa aagccctatg
     1621 aatgtaagca gtgtggaaaa gcactttctc atctgaaaag ctttcagaga cacatgataa
     1681 tgcacactgg agatggacct cataaatgta agatatgtgg gaaaagcttt gattctccca
     1741 gttcatttcg aagacatgaa agaattcaca ctggggagag accctataag tgtaaactat
     1801 gtgggaaagg cttcaggtct tccagttaca ttcaactaca tgaaaggact cacactggag
     1861 agaaacccta tggttgtcag caatgtggga aagcattatc tgatctctca agctttcgaa
     1921 gacacatgat aacacatact ggaaatggac ctcataaatg taagatatgt gggaaaggct
     1981 ttgattatcc cagttcagtg caaagacatg aaagaactca cactggagag aaaccctatg
     2041 aatgcaagga atgtggtaaa gccttcagtc attcaagtta cttacgaata cacgaaagag
     2101 ttcatactgg agagaagccg tataaatgta aggaatgtgg gaaaccattc cattgtccca
     2161 gtgcctttca taaacatgaa aggacccaca gtatggagaa accctataag tgtaaagaat
     2221 gtggggaagc atttcattgt atcagttcct ttcataaaca tgaaatgact cactagagaa
     2281 aacccctatg agtgttgaac atgtgagaaa gccttaagta ctttcagctt cttacaaata
     2341 cataagagac tcacactgaa aaaagttgta tgaatataaa aatgtactaa aaccttccat
     2401 ttttttcagt accttttgaa aacatgacca aactcatact tcaaaaatat atatataatg
     2461 aatgtgagga atatgaaaaa actttctttg tctagcaaac tttcaaaggt ggttattata
     2521 acatactagc aatggacctt actactgtaa ggaatgtaga aatgcattta ctagtcctaa
     2581 ttcatttcag ttacatgaaa gatttcaaac tgcagagaac cactatgaat gtaaacaatg
     2641 tggtaaagca tttagtagct tcagtttctt ttgaatacag tcttctctag tttctgaggt
     2701 gaattgattc cagcaccctc aggaatacct atattcagag atattcaagt ccctgatatt
     2761 aaaaacagca tatttgcata taatctaggc acatttttct gtatatctta aatcatttct
     2821 agattactta taatacacaa tgcattgtaa attctgtata agttgctttt gtattattta
     2881 gggaatcatg acaagaaaaa agtctacatg ttcagtacaa atacaactgt cattcattgt
     2941 cctaagtacg tgtacatgtc agcaacaatg tcaggatctg tggagtttgc gagtataaga
     3001 tctttaagtg ttgaaggttt catctccata attgcagctg ctttagctac aaatattata
     3061 ggaagctgtt ccttcttttt ctttacatca ccaaaccttc cagtggttat aggcattttg
     3121 ttatccttca agtgacctgg agcctttgtt gcatgacagg attgtacctg aagatcacat
     3181 tctttaacaa ttggacctac tgaatctgta aaactactag aagaaaacat attgaaaata
     3241 cttcaggaca ttggtttagg caaagatttt atggctaata cctcaaagca cagacaacaa
     3301 agataaaaat agacaaatga gactatctta cactaaaaag tagctgtgca aagtaaaggg
     3361 aacaacaaga gtgcagagaa aacctgttga atatgagaga atatttgcaa actatgcgac
     3421 aagggactaa tatccaaata tacaaggaac tcaaacatct caacagcaaa aaatataaat
     3481 aatcccatta aagtgggaaa aggatgtgaa cagacagttc tcaaaagaag acatgcaaat
     3541 ggccaaaaag tatatggaaa tatgttcaac atcactaatg attaggaaaa tgcaaattga
     3601 aaccacaatg agatactcta cttagaattg ttcttactaa aaaagataaa aaacaacaaa
     3661 tgctgatgag gatgtggaga aaagaaaact ttcactgttg gtgaaagtat aaattagaac
     3721 aactactgtg gaaaacagta tgtagatttc tcaaaaacct aaaaatagaa ccaccacatg
     3781 atccagcaaa ccaagtataa ccacaggaaa agaaatcagt atatcaaaga gatacttgca
     3841 cttgcatatt tatcacagca ctattcatga taacaaagat atggaattaa cctaagcatc
     3901 catcagtgga cacagggata aagaaaatgt ttatgtacac agtggaatac tatttggcca
     3961 taaaaaagag taaaatgtta ttgctaacaa catggatgga acttgaggtc attatggtaa
     4021 gtgaaataag ccaggcacag aaagacaaat accacatgtt ctcacttata tgtgggaggt
     4081 gaaaaacttc acctcatgga gatagggaat agaataagtt atccggggct gagaagggga
     4141 aatgaagaga aattggtgaa tatgtacaaa tttccattta gatcaaagga ataagttctg
     4201 atgttagaaa gcatactaga gtgaactata gttagcaaaa atatattgca tatttcaaag
     4261 tagttggaag agaggacttg aaatgttacc aacacataga agtggtaaat actcaagatc
     4321 atggataccc caaatacgct gacttgacca ttacacattc tatgcatgca agaaatgctc
     4381 atgtgtacct tatatatatg taaaatatgt atcaataaaa gaaaatatat aagatagttt
     4441 taaaataa
//
