LOCUS       NM_001001415            4785 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 429 (ZNF429), transcript variant
            1, mRNA.
ACCESSION   NM_001001415
VERSION     NM_001001415.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4785)
  AUTHORS   Kim,H., Ramsay,E., Lee,H., Wahl,S. and Dionne,R.A.
  TITLE     Genome-wide association study of acute post-surgical pain in humans
  JOURNAL   Pharmacogenomics 10 (2), 171-179 (2009)
   PUBMED   19207018
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   2  (bases 1 to 4785)
  AUTHORS   Abrink,M., Aveskogh,M. and Hellman,L.
  TITLE     Isolation of cDNA clones for 42 different Kruppel-related zinc
            finger proteins expressed in the human monoblast cell line U-937
  JOURNAL   DNA Cell Biol 14 (2), 125-136 (1995)
   PUBMED   7865130
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010615.9, DA533537.1 and BM981242.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001001415.3.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DA533537.1, SRR3476690.968948.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000358491.9/ ENSP00000351280.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-92                AC010615.9         161268-161359
            93-582              DA533537.1         93-582
            583-4148            AC010615.9         192132-195697
            4149-4785           BM981242.1         16-652              c
FEATURES             Location/Qualifiers
     source          1..4785
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p12"
     gene            1..4785
                     /gene="ZNF429"
                     /note="zinc finger protein 429"
                     /db_xref="GeneID:353088"
                     /db_xref="HGNC:HGNC:20817"
     exon            1..173
                     /gene="ZNF429"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..2195
                     /gene="ZNF429"
                     /note="isoform a is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 429 isoform a"
                     /protein_id="NP_001001415.2"
                     /db_xref="CCDS:CCDS42537.1"
                     /db_xref="GeneID:353088"
                     /db_xref="HGNC:HGNC:20817"
                     /translation="MGPLTFTDVAIEFSLEEWQCLDTAQQNLYRNVMLENYRNLVFLG
                     IAVSKPDLITCLEKEKEPCKMKRHEMVDEPPVVCSHFAEDFWPEQDIKDSFQKVTLRR
                     YDKRGHENLQLRKGYKTVGDCKLYKGGYNGLNQCLTLTQSKMYHCDIYVKVFYAFSNA
                     DRYKTRHTGKKPFQCKKCGKSFCMLSQLTQHKKIHIRENTYRCKEFGNAFNQSSALTN
                     HKRIYVGEKHYRCEECGKAFNHYSTLTNHKRIHTGEKPYKCKECGKAFSRYSTLTTHK
                     RIHSGEKPYKCDECGKTFSISSTFTKHKIIHTEEKPYKCKECGKAFNRSSTLTSHKRI
                     HTGEKPYKCEECGKAFNWSSTLTKHKVIHTGEKPYKCEECGKAFNQSSRLTRHKKIHT
                     GEEPYKFEKCGRVFTCSSTLTQDKKIHTGEKPYNCEECGKVFTYSSTLTRHKRIHTEE
                     KPYKCNECGKAFNRSSHLTSHRRIHTGEKPYKCEECGKAFKQSSNLNSHKKIHSGEKP
                     YKCEECGKAFILSSRLTQHKKIHTGEKPYKCEECGKAFNRSSRLTQHKKIHTGEKPYK
                     CKQCDKAFTHSSNLSSHKKIHSGEKPYKCEECGKAFNRSSRLTQHKKIHTREKPYKCE
                     ECAKAFTRSSRLTQHKKIHRMGVVAHACNPSTLGGRGGRITRSGDRDRPG"
     exon            174..300
                     /gene="ZNF429"
                     /inference="alignment:Splign:2.1.0"
     exon            301..396
                     /gene="ZNF429"
                     /inference="alignment:Splign:2.1.0"
     exon            397..4785
                     /gene="ZNF429"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4761..4766
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF429"
                     /note="hexamer: AATAAA"
     polyA_site      4785
                     /gene="ZNF429"
                     /note="major polyA site"
ORIGIN      
        1 acggtttccg gaatatggcg gggcgtttgg ctcttgctgc agccagagct ccaggtctcg
       61 tcttcatttc tgtgtccttt gttcttagag gcccagcctg tgtggccctg tgacccgcag
      121 atattgggag atacacagct aagactccag gaccccctgg aagcctagaa atgggaccat
      181 tgacatttac agatgtggcc atagaattct ctctggagga gtggcagtgc ctggacacag
      241 cacaacagaa cttatataga aatgtgatgt tagagaacta cagaaacttg gtcttcctgg
      301 gtattgctgt ttctaagcca gacctaatca cttgtctaga gaaagaaaaa gaaccctgca
      361 agatgaagcg acatgaaatg gtggatgaac ccccagttgt gtgttctcat tttgctgaag
      421 acttttggcc agagcaagac ataaaagatt ctttccaaaa agtgacactg aggagatatg
      481 ataaacgtgg acatgagaac ttacaattaa gaaaaggcta taaaactgta ggtgattgta
      541 agctatacaa aggaggttat aatggactta accaatgttt gacacttacc cagagcaaaa
      601 tgtatcactg tgatatatat gtaaaagtct tttatgcatt ttcaaatgca gatagataca
      661 agacaagaca tactggaaag aaacctttcc agtgtaaaaa atgtggcaaa tcattttgca
      721 tgctttcaca actaactcaa cataagaaaa ttcatattag agagaatacc tacagatgta
      781 aagaatttgg caatgccttt aatcagtcct cagcccttac taaccataag agaatttatg
      841 ttggtgagaa acactacaga tgtgaagaat gtggcaaagc atttaaccac tactcaaccc
      901 ttactaacca taagagaatt catactggag agaaacccta caaatgtaaa gaatgtggca
      961 aagcctttag caggtactca acccttacta cccataagag aattcattct ggagagaagc
     1021 cctacaaatg tgatgaatgt ggcaaaacct ttagcatatc ctcaaccttt actaaacata
     1081 agataattca tactgaagag aaaccctaca aatgtaaaga atgtggcaaa gcctttaacc
     1141 ggtcctcaac ccttactagc cataagagaa tacatactgg tgagaaaccc tacaaatgtg
     1201 aagaatgtgg caaagccttt aactggtctt caactcttac taaacataag gtaattcata
     1261 ctggagagaa gccctacaaa tgtgaagaat gtggcaaagc ttttaaccag tcttcaagac
     1321 ttactcgaca taaaaaaatt catactggag aggaacccta caaatttgaa aaatgtggca
     1381 gagtttttac ctgttcctca acacttactc aagacaagaa aattcatact ggagagaaac
     1441 cctacaattg tgaagaatgt ggcaaagttt ttacctattc ctctacactt actagacata
     1501 agagaattca tactgaagag aaaccctata aatgtaacga atgtggcaaa gcttttaacc
     1561 ggtcctcaca ccttactagc cataggagaa ttcatactgg agagaaaccc tacaaatgtg
     1621 aagaatgtgg caaagccttt aagcagtcct caaaccttaa cagtcataaa aaaattcata
     1681 gtggagagaa accctacaaa tgtgaagaat gtggcaaagc ttttatcctg tcctcaagac
     1741 ttactcaaca taagaaaatt catactggag agaaacctta caaatgtgaa gaatgtggca
     1801 aagcttttaa ccggtcctca agacttactc aacataagaa aattcatact ggagagaaac
     1861 cctacaaatg taaacaatgt gacaaagctt ttacccactc ctcaaacctt agtagtcata
     1921 agaaaattca tagtggagag aaaccctaca aatgtgaaga atgtggcaaa gcttttaatc
     1981 ggtcctcaag acttactcaa cataagaaaa ttcatactag agagaaacct tacaaatgtg
     2041 aagaatgtgc caaagctttt acccggtctt caagacttac tcaacataag aaaattcata
     2101 ggatgggtgt ggtggctcat gcctgtaatc ccagcacttt gggaggcaga ggtgggcgga
     2161 tcacgaggtc aggagatcga gaccgtcctg gctaacatgg tgaaaccccg tctctactaa
     2221 aaatacaaaa aaaaaaaaaa aaaaaattag ccaggcgtgg tggtgggcac ttgtagtccc
     2281 acctactcgg gaggctgagg caggagaatg gcctgaaccc ggaggtggag cttgcattga
     2341 gccaagatca caccactgca ctccagcctg ggtgacagag ccagactcca tctcaaaaaa
     2401 aaaaaaaaaa aaaaaagaaa agaaaattca taggccaggt atggtggctc atgcctgcct
     2461 gtaatcccag cactttggga ggccgaggcg ggtggatcac gaggtcagga gttcaagacc
     2521 agcctggtca acatggtaaa accccatctc tactaaaaat acaaaaatta gctggatgtg
     2581 gtggcacatg cctgtagtcc tagctacttg ggaggctgag gcaggagaat tgcttgaacc
     2641 tgggagccag aggtagcagt gagctgagat cacgccacta cactccagcc tggatgacaa
     2701 aacaagactc tgtctaaaaa atatataaat aaataaaaga aagaaaattc atagtagaga
     2761 gaaaccttac aaatgtgtag aatgtggcaa aactcgtttt aactaatgct cacatcttat
     2821 tgcatagaaa agcatttata cctgaaaaaa ggtatacaaa tttaaaaaat gtggaaaagc
     2881 cattaaaatc tgttcacatc ttaacaacag agagttgata cttaataaga gcattgtaag
     2941 tgcaattact gtcaaacaat cttgtagaaa atatcatcct ttaaagtgaa tgagactagt
     3001 ctgaggaaaa acattacaaa tgtaaagagg gttatagtgc atttacttgt atcacagatc
     3061 ttgttgtaca cattttatac tagaggaaaa ccctgaagca gttgcaccaa ctttgttcaa
     3121 catcagaaat ttatattgga gaaaaatcca gcaagtgtaa taaatttgga aaaacttttt
     3181 tttccccaaa aactatacct caggaaacaa tggagagttt atattaacat atatttttgc
     3241 atatggccat atgtataaaa atatttaatt caaaattgaa tttaaaaagt ctacataaat
     3301 atcatacata gatatgtatg atattgaata catgtattaa atacatagaa tatgatattt
     3361 aatacataga aaagtctaca tgaatatcag aatttacagt agaaacaact aagacacaaa
     3421 cacttgagac attacactaa agtgctgagt atagaaaata aaactaaagt tgttaaatta
     3481 tttgtatata acttttaaaa gagtggaaga tattttgcaa agttatattc aaagtgtact
     3541 ttttatttat ttttttgaga tggagtctca ctttgttgcc tacgttggag ttcagtggca
     3601 caatttcagc ttgctgccaa cttcgacctt tgggttcaag cagttctcct gccacagcct
     3661 cctgagtagc tgggaataca ggcatacacc agcatgtctg gctatttttt tttttttttg
     3721 tatttttagt agagatgaga tttcaccatt ttgtccaggg tggtctcaaa ctcttcatct
     3781 caagtgatct gcccaccttg gcctcccaga gtgctgggat tgcagccatg agccactgca
     3841 cccagcccaa agtatgcttt taaaaatatg tatatatata aaatttttga aaagcaaatt
     3901 atgatataat tcaagtatca aattacttca tgctgtttca ttgttcctat tcacatgtga
     3961 aagcatgtga tcaattattg ctgcatcaca tatagactca ttaggtggaa attatggcct
     4021 cttctgtaaa aaagtaagga cattaaaatg taagatgctt gatgaaaatc taagtggaga
     4081 ggctctttgt ggttaactta ttgagtgatg tatgaggtcg atgttcagag taatatgcct
     4141 ctgtattaca gtgatagaaa atatttttta gttaaaagtg aatttataat aaaattgtaa
     4201 atcattttag tgattgagct tttatgttat aaaatgcagt atatttcaaa atttttaaat
     4261 tatatgtaaa tttgatttta tttgttacca tgttaagact attgtgcatt taatgaagca
     4321 ttattatgct atcaacttta acctatccca cgttactcaa gggtgtagct aaatgaaggt
     4381 agcagtatgc tatttagtaa catagtggaa tagcatctct agtaatctct tttgccagta
     4441 gctttaactg gcagataagt taatattgtt cccataggtt aaatatttat cctttttttg
     4501 atatttaaat ttttttctta tttttttgtg ggtacataat atgtgtatat atttatgcaa
     4561 atctggcata ttttgataga ggcatacaat atgtaataat tacatcaatt acatcagggt
     4621 aaattatgta gccattactt gtaacattta tcttttacaa acaactcaat tatgcacttt
     4681 tagttatttt aaagtgtaca attaaattgc tattgactgc atggttatct ttgtggtata
     4741 aaaatttata tataagtata aataaactca tttctgagtc ttaaa
//
