LOCUS       NM_182498               1162 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens zinc finger protein 428 (ZNF428), mRNA.
ACCESSION   NM_182498
VERSION     NM_182498.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1162)
  AUTHORS   Camara-Quilez,M., Barreiro-Alonso,A., Vizoso-Vazquez,A.,
            Rodriguez-Belmonte,E., Quindos-Varela,M., Lamas-Maceiras,M. and
            Cerdan,M.E.
  TITLE     The HMGB1-2 Ovarian Cancer Interactome. The Role of HMGB Proteins
            and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and
            Drug-Response
  JOURNAL   Cancers (Basel) 12 (9), 2435 (2020)
   PUBMED   32867128
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1162)
  AUTHORS   Barreiro-Alonso,A., Camara-Quilez,M., Salamini-Montemurri,M.,
            Lamas-Maceiras,M., Vizoso-Vazquez,A., Rodriguez-Belmonte,E.,
            Quindos-Varela,M., Martinez-Iglesias,O., Figueroa,A. and
            Cerdan,M.E.
  TITLE     Characterization of HMGB1/2 Interactome in Prostate Cancer by Yeast
            Two Hybrid Approach: Potential Pathobiological Implications
  JOURNAL   Cancers (Basel) 11 (11), 1729 (2019)
   PUBMED   31694235
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1162)
  AUTHORS   Barreiro-Alonso,A., Lamas-Maceiras,M., Garcia-Diaz,R.,
            Rodriguez-Belmonte,E., Yu,L., Pardo,M., Choudhary,J.S. and
            Cerdan,M.E.
  TITLE     Delineating the HMGB1 and HMGB2 interactome in prostate and ovary
            epithelial cells and its relationship with cancer
  JOURNAL   Oncotarget 9 (27), 19050-19064 (2018)
   PUBMED   29721183
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN355560.1, BC015950.2, AC006276.1 and BC045799.1.
            
            On Nov 23, 2018 this sequence version replaced NM_182498.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC045799.1, SRR1163655.466521.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1966682, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000300811.8/ ENSP00000300811.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                CN355560.1         241-288
            49-929              BC015950.2         1-881
            930-970             AC006276.1         28632-28672         c
            971-1162            BC045799.1         945-1136
FEATURES             Location/Qualifiers
     source          1..1162
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.31"
     gene            1..1162
                     /gene="ZNF428"
                     /gene_synonym="C19orf37; Zfp428"
                     /note="zinc finger protein 428"
                     /db_xref="GeneID:126299"
                     /db_xref="HGNC:HGNC:20804"
     exon            1..72
                     /gene="ZNF428"
                     /gene_synonym="C19orf37; Zfp428"
                     /inference="alignment:Splign:2.1.0"
     exon            73..278
                     /gene="ZNF428"
                     /gene_synonym="C19orf37; Zfp428"
                     /inference="alignment:Splign:2.1.0"
     CDS             203..769
                     /gene="ZNF428"
                     /gene_synonym="C19orf37; Zfp428"
                     /note="enzyme-like protein PIT13"
                     /codon_start=1
                     /product="zinc finger protein 428"
                     /protein_id="NP_872304.2"
                     /db_xref="CCDS:CCDS12626.1"
                     /db_xref="GeneID:126299"
                     /db_xref="HGNC:HGNC:20804"
                     /translation="MTETREPAETGGYASLEEDDEDLSPGPEHSSDSEYTLSEPDSEE
                     EEDEEEEEEETTDDPEYDPGYKVKQRLGGGRGGPSRRAPRAAQPPAQPCQLCGRSPLG
                     EAPPGTPPCRLCCPATAPQEAPAPEGRALGEEEEEPPRAGEGRPAGREEEEEEEEEGT
                     YHCTECEDSFDNLGELHGHFMLHARGEV"
     exon            279..1162
                     /gene="ZNF428"
                     /gene_synonym="C19orf37; Zfp428"
                     /inference="alignment:Splign:2.1.0"
     regulatory      910..915
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF428"
                     /gene_synonym="C19orf37; Zfp428"
                     /note="hexamer: AATAAA"
     polyA_site      929
                     /gene="ZNF428"
                     /gene_synonym="C19orf37; Zfp428"
                     /note="major polyA site"
     regulatory      1140..1145
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF428"
                     /gene_synonym="C19orf37; Zfp428"
                     /note="hexamer: AATAGA"
     polyA_site      1162
                     /gene="ZNF428"
                     /gene_synonym="C19orf37; Zfp428"
ORIGIN      
        1 acttgcgacg caggcgcaga ggctgggcgt gcagccgccg ccgcagagcc ggagcggggg
       61 ccgccggcgc cgcatccctc tctacctgcc aacatcctgt attagagaac ttgtggccgg
      121 aggtgtggct gtggagagct ggccggggag ggacgctgct cagctgctgc tctgctcctg
      181 tctcctgtcc cctcccccgg tcatgacaga gacccgtgag ccagctgaga ctgggggcta
      241 cgccagcttg gaagaagatg atgaagacct ttccccaggc cccgagcatt cctctgattc
      301 agaatacact ctctcagagc cggactccga agaggaagaa gatgaggagg aggaggaaga
      361 ggagaccact gacgatcctg aatatgatcc tggctacaag gtgaagcagc gccttggcgg
      421 gggccgtggt ggcccatccc gccgggcccc ccgtgcagcc cagcccccgg cccagccttg
      481 ccagctctgt ggccgctcac cccttgggga ggccccaccg ggaaccccac cctgccggct
      541 ctgctgccct gctacagccc cccaggaagc accagcccct gaaggcaggg ccctcgggga
      601 ggaagaggag gaaccacctc gggctgggga gggccgacca gctgggcggg aggaggagga
      661 ggaagaggag gaggagggaa cctaccactg tacggaatgt gaggattcct tcgacaacct
      721 gggggagctg cacgggcact tcatgctgca tgcccggggt gaggtgtagg cagagccccc
      781 atacggggag cttggcagaa ggggtggggt gggaggaggg ggctgaggaa attggggttg
      841 tgacagtggt catgggggat ggggtactgc cggtctgtgt tgtcttagaa gtagatgtgt
      901 gatggccaga ataaaagcca aaatctgtat ctgtgtgtgt tggttcagag tgtgtgtgtg
      961 tgtgtgtgta ttcccgcccg tgtgtgtgtt tgtgtgtgtg tgtgtgtgtg tgtattcccc
     1021 ctgggctcct tcttggggaa ccttggggtc ttttgggaaa gataacattt actgcgtgct
     1081 tgtattcgat gaggtttcca tgtatttact tacagacccc ataatgtaaa ggctctaata
     1141 atagaatttt gtttctcact ca
//
