LOCUS       NM_152475               4685 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 417 (ZNF417), transcript variant
            1, mRNA.
ACCESSION   NM_152475
VERSION     NM_152475.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4685)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 4685)
  AUTHORS   Sahni,N., Yi,S., Taipale,M., Fuxman Bass,J.I.,
            Coulombe-Huntington,J., Yang,F., Peng,J., Weile,J., Karras,G.I.,
            Wang,Y., Kovacs,I.A., Kamburov,A., Krykbaeva,I., Lam,M.H.,
            Tucker,G., Khurana,V., Sharma,A., Liu,Y.Y., Yachie,N., Zhong,Q.,
            Shen,Y., Palagi,A., San-Miguel,A., Fan,C., Balcha,D., Dricot,A.,
            Jordan,D.M., Walsh,J.M., Shah,A.A., Yang,X., Stoyanova,A.K.,
            Leighton,A., Calderwood,M.A., Jacob,Y., Cusick,M.E.,
            Salehi-Ashtiani,K., Whitesell,L.J., Sunyaev,S., Berger,B.,
            Barabasi,A.L., Charloteaux,B., Hill,D.E., Hao,T., Roth,F.P.,
            Xia,Y., Walhout,A.J.M., Lindquist,S. and Vidal,M.
  TITLE     Widespread macromolecular interaction perturbations in human
            genetic disorders
  JOURNAL   Cell 161 (3), 647-660 (2015)
   PUBMED   25910212
REFERENCE   3  (bases 1 to 4685)
  AUTHORS   Yu,H., Tardivo,L., Tam,S., Weiner,E., Gebreab,F., Fan,C.,
            Svrzikapa,N., Hirozane-Kishikawa,T., Rietman,E., Yang,X.,
            Sahalie,J., Salehi-Ashtiani,K., Hao,T., Cusick,M.E., Hill,D.E.,
            Roth,F.P., Braun,P. and Vidal,M.
  TITLE     Next-generation sequencing to generate interactome datasets
  JOURNAL   Nat Methods 8 (6), 478-480 (2011)
   PUBMED   21516116
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BP358797.1, BC025783.1 and AC010326.7.
            
            On Nov 22, 2018 this sequence version replaced NM_152475.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DB091954.1, BC025783.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2142348 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000312026.6/ ENSP00000311319.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-16                BP358797.1         19-34
            17-698              BC025783.1         1-682
            699-4685            AC010326.7         60347-64333         c
FEATURES             Location/Qualifiers
     source          1..4685
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..4685
                     /gene="ZNF417"
                     /note="zinc finger protein 417"
                     /db_xref="GeneID:147687"
                     /db_xref="HGNC:HGNC:20646"
     exon            1..214
                     /gene="ZNF417"
                     /inference="alignment:Splign:2.1.0"
     CDS             182..1909
                     /gene="ZNF417"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 417 isoform 1"
                     /protein_id="NP_689688.2"
                     /db_xref="CCDS:CCDS12965.1"
                     /db_xref="GeneID:147687"
                     /db_xref="HGNC:HGNC:20646"
                     /translation="MAAAAPRRPTQQGTVTFEDVAVNFSQEEWCLLSEAQRCLYRDVM
                     LENLALISSLGCWCGSKDEEAPCKQRISVQRESQSRTPRAGVSPKKAHPCEMCGLILE
                     DVFHFADHQETHHKQKLNRSGACGKNLDDTAYLHQHQKQHIGEKFYRKSVREASFVKK
                     RKLRVSQEPFVFREFGKDVLPSSGLCQEAAAVEKTDSETMHGPPFQEGKTNYSCGKRT
                     KAFSTKHSVIPHQKLFTRDGCYVCSDCGKSFSRYVSFSNHQRDHTAKGPYDCGECGKS
                     YSRKSSLIQHQRVHTGKTAYPCEECGKSFSQKGSLISHQRVHTGERPYECREYGKSFG
                     QKGNLIQHQQGHTGERAYHCGECGKSFRQKFCFINHQRVHTGERPYKCGECGKSFGQK
                     GNLVQHQRGHTGERPYECKECGKSFRYRSHLTEHQRLHTGERPYNCRECGKLFNRKYH
                     LLVHERVHTGERPYACEVCGKLFGNKNCVTIHQRIHTGERPYECNECGKSFLSSSALH
                     VHKRVHSGQKPYKCSECGKSFAECSSLIKHRRIHTGERPYECTKCGKTFQRSSTLLHH
                     QSSHRRKAL"
     exon            215..344
                     /gene="ZNF417"
                     /inference="alignment:Splign:2.1.0"
     exon            345..4685
                     /gene="ZNF417"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1953..1958
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF417"
                     /note="hexamer: ATTAAA"
     polyA_site      1979
                     /gene="ZNF417"
                     /note="major polyA site"
     polyA_site      3084
                     /gene="ZNF417"
     polyA_site      4685
                     /gene="ZNF417"
ORIGIN      
        1 agtagcggct gtgtatcggt gacgcgggtg tttccccagt ttgtggcccc tgagtgctgg
       61 ggggggaccg cggtgactga acctagaagg tggagaggaa tcgtcctcgg tgcccagagg
      121 cggctctgca gccccgtgac ggcgaccact gctcccgggc cgtgcttccc caagtagtcc
      181 gatggcagcg gctgcgccga ggcgcccgac tcagcagggc actgtgacct ttgaagatgt
      241 ggctgtgaac ttttcccagg aggagtggtg tcttcttagt gaggctcaga ggtgcttgta
      301 ccgtgatgtg atgctagaga acctggctct catatcctcg ctgggttgtt ggtgtggatc
      361 aaaagatgag gaggcacctt gtaagcagag aatttctgta caaagagagt ctcagagcag
      421 gactcctagg gcaggtgttt ctcctaagaa ggctcacccc tgtgaaatgt gtggcctcat
      481 cttggaggat gtttttcact ttgctgacca ccaggaaact catcacaagc agaagctgaa
      541 caggagtgga gcatgtggaa aaaacttgga tgacactgca taccttcatc agcaccagaa
      601 gcagcatatt ggagagaaat tctacagaaa gagtgtcaga gaagcatcgt ttgtaaagaa
      661 acgtaagctc agggtgtcac aggagccatt tgtcttccgc gagtttggga aggacgttct
      721 gcccagttca ggattgtgcc aagaagcagc tgctgtagag aagacagaca gtgaaactat
      781 gcatggccca ccctttcagg agggaaaaac taattacagt tgtggaaaac gcacaaaagc
      841 cttcagcacc aaacactcag ttattccaca ccagaaactt ttcactagag atggatgtta
      901 tgtgtgcagt gattgtggaa aatcctttag cagatatgtc agcttcagta atcatcagcg
      961 agatcacact gcaaaaggac cttatgattg tggagagtgt gggaaatctt atagtcgaaa
     1021 gagcagcctt attcaacatc agcgagtcca cactggaaag acagcttatc cctgtgagga
     1081 gtgcgggaaa tcttttagtc agaagggcag ccttattagc catcagcgtg ttcacactgg
     1141 agaaaggcct tatgagtgta gagaatatgg gaaatctttt ggtcaaaagg gtaacctcat
     1201 tcaacatcag caaggtcaca ctggagagag agcttatcac tgtggggaat gtgggaaatc
     1261 ttttcgtcag aagttctgct ttattaacca tcagcgtgtt cacactggag aaaggcctta
     1321 caagtgtgga gaatgtggaa aatcttttgg tcaaaagggc aacctcgttc aacatcagcg
     1381 aggtcatact ggagaaaggc cctatgagtg caaggaatgt gggaaatcat ttaggtacag
     1441 atcccacctc actgaacacc agagacttca cactggggaa agaccttaca attgtaggga
     1501 atgtgggaaa ttatttaaca ggaagtatca tcttctcgtt catgagagag ttcacactgg
     1561 agaaaggcca tatgcgtgtg aggtatgtgg gaaattattt ggtaataaga actgcgtgac
     1621 tatacatcag aggattcaca ctggagaaag gccgtatgaa tgcaatgaat gtgggaaatc
     1681 atttctttcc agctctgcgc ttcatgttca taaaagagtt cattctggac aaaagcctta
     1741 taagtgcagt gaatgtggaa aatcctttgc tgaatgttcc agtctcatta aacacaggag
     1801 aattcacact ggagaaaggc cttatgaatg taccaaatgt ggaaaaacat ttcagcgaag
     1861 ctctaccctc cttcatcatc agagttcaca caggagaaag gccttatgag tgcagtgaat
     1921 atgggaaatc gtttgctgaa acatcccgtc tcattaaaca caggagagtt catactggag
     1981 aaaggcctta tgagtgctgt caatctggga aacatcagaa tgtctgctct ccttggtctt
     2041 aagagacttc gcattggaac ggagtctcat tctgtcaccc aggctggagt gcagtggtgc
     2101 aatcttggct cactgcaact tgggcctccc aggttcaagt gattctccta cctcagcctc
     2161 ccaaggagct gagattacga gtacaccaca ccatgcccgg ccaaatactt ggttttcagt
     2221 accacaagag ctatgagctg gttatccact tcatgtggaa tcataagtgt ccccaagtga
     2281 caatacgtat agattgctgg gcagtgaaac agttaagatg tcaccgtagc ttgctttcta
     2341 ttcaacatct ttctaagatt accttactat ttcttttgtt ccaagtttgt atttcctcag
     2401 agttctcaca tatggaaagg atacacactt tgtagaaaca agaactttat gttatccaag
     2461 ttctgggata gccatgagct ccaattacct cagagctccg agtcctctac tcagtacccg
     2521 ttgagattta tgtgttctga ggcttttgtc ttctagctac ttacttcatt ctccatgggt
     2581 aacgtcattc atccacatta actaatttcc tcactccaag ctcttttctg gagataatct
     2641 ccagtccctg tgcagacact gtcattgcac tttctgctga aatggtagtt tcttgccagc
     2701 aaggtgagat tatggaatcc agaatctttt ttcaggggcc acatgcccat ttccccactt
     2761 gcatgaatgt cgacactgta gccacagttt tggccgtaaa tgtgaatttg gcaagtaacc
     2821 actgttccca aattgggaaa tgtcccagtc agaagaagat tatctgggac actgatactg
     2881 acagggagat gggacattct gagggacccg gaggcaggga gccacctcct cagcttccct
     2941 gagggctgcc tagaatctct cttgtttcct ctcactctga attattcttc ctctcatgac
     3001 tgaccaaaca catggaacct cacaaagtcc attttaagag ctttatcttg tgaagtgaag
     3061 aacatgaaga tagtttgaat caaagttatt gagtggacac ttaatgtctt tataacattt
     3121 tttacatatg tgtttgtgtt ttttggggag cataatttgc aaatggaata tctgttattt
     3181 tactaagatg cttcatggat acaagagtta aaacttcctg tcccatttag tgaaacaaaa
     3241 ggttaagaaa tgtggataaa gcttgtaagt tagaaatggc aagataatca gctatatgaa
     3301 gaatctcagc tgggtgtttt ggctcaggcc tgtaatccca gcactttggg aggctgaggt
     3361 gggtggctta caaggtcagg agttcaagac caccctggac aatatggtga aaccctgtct
     3421 ctactaaaaa tacaaaaatt acccaagcat agtggtgggt gcctgtagtc ccagctgctt
     3481 gggaggctga ggcaggagaa ttcgttaaac ctgggaggca taggttgcag tgagccgaga
     3541 ttgcaccact gcactccagc ctggtgacag agcgagactc cgtctcaaaa aaaaaaaaaa
     3601 aaaaaaaaaa aaatctcaat ccctaaatgt taccttttat aacagcaggt tatatgggct
     3661 tagatattat ccctaaattt tttttttttt ttttttttga gacagagtct cactctgtca
     3721 cccaggctga agtgcaatgg catggtctcg gctcactgca acctccgcct cccaggttca
     3781 agtgattctc ttgcctcagc ctcccaagta gctgggccta taggttccct ccaccacgcc
     3841 cacctaattt ttgtattttt agtagagatg ggctttcact acgttagcca ggctggtctc
     3901 aaacttgtga cctcatgatc cacccccctc agcctcctaa agtgctggga ttacaggcat
     3961 ctgccacggc actcggctta tccctagaaa tcctatgata gcatgatgta taggcaccta
     4021 aaggcatggc acttgagaaa tgtgaataag attgtaagtt acaaatagca aggtacagtc
     4081 agatgttaac agtctcagcc cctaaatgtc accttgtatt acagcatgtt atataagcac
     4141 atacaggcac atacatgaaa tagtgatact tcattctcag taatattttt catccttctc
     4201 actggaaaga tctttgatga tttttaatca acataggagt ttcaatgata tctagaagtt
     4261 taaaagggct cgttcaaaca aattatgacc atacaccctg aagagtatgt gtctgtctct
     4321 tgtggtgtaa atttttattt tattacaccc aattatgttc ccacaaaacc tttataattg
     4381 ggaaattaag gagccttcct cggaaatgga ggttgcaatc agctgagatg gtaccactgc
     4441 actctagcct gggcaaaaga gcaaggccct gcctcaaaaa aaacaaaact tttttcttca
     4501 taaactacag tttatatagg caaaactttc agtactaagc aattttagtc tctgcaggct
     4561 cttgtcttga attaatacaa cttttgttaa ttctcttatg aagttaaatc ttcctgcttg
     4621 tatgcaactt atatgttgaa atttttttgt acaaaagatt catacatctt tcctgtttga
     4681 aatta
//
