LOCUS       NM_017879               2545 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 416 (ZNF416), transcript variant
            1, mRNA.
ACCESSION   NM_017879
VERSION     NM_017879.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2545)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 2545)
  AUTHORS   Gerhard,D.S., Wagner,L., Feingold,E.A., Shenmen,C.M., Grouse,L.H.,
            Schuler,G., Klein,S.L., Old,S., Rasooly,R., Good,P., Guyer,M.,
            Peck,A.M., Derge,J.G., Lipman,D., Collins,F.S., Jang,W., Sherry,S.,
            Feolo,M., Misquitta,L., Lee,E., Rotmistrovsky,K., Greenhut,S.F.,
            Schaefer,C.F., Buetow,K., Bonner,T.I., Haussler,D., Kent,J.,
            Kiekhaus,M., Furey,T., Brent,M., Prange,C., Schreiber,K.,
            Shapiro,N., Bhat,N.K., Hopkins,R.F., Hsie,F., Driscoll,T.,
            Soares,M.B., Casavant,T.L., Scheetz,T.E., Brown-stein,M.J.,
            Usdin,T.B., Toshiyuki,S., Carninci,P., Piao,Y., Dudekula,D.B.,
            Ko,M.S., Kawakami,K., Suzuki,Y., Sugano,S., Gruber,C.E.,
            Smith,M.R., Simmons,B., Moore,T., Waterman,R., Johnson,S.L.,
            Ruan,Y., Wei,C.L., Mathavan,S., Gunaratne,P.H., Wu,J., Garcia,A.M.,
            Hulyk,S.W., Fuh,E., Yuan,Y., Sneed,A., Kowis,C., Hodgson,A.,
            Muzny,D.M., McPherson,J., Gibbs,R.A., Fahey,J., Helton,E.,
            Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M.,
            Madari,A., Young,A.C., Wetherby,K.D., Granite,S.J., Kwong,P.N.,
            Brinkley,C.P., Pearson,R.L., Bouffard,G.G., Blakesly,R.W.,
            Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J.,
            Myers,R.M., Butterfield,Y.S., Griffith,M., Griffith,O.L.,
            Krzywinski,M.I., Liao,N., Morin,R., Palmquist,D., Petrescu,A.S.,
            Skalska,U., Smailus,D.E., Stott,J.M., Schnerch,A., Schein,J.E.,
            Jones,S.J., Holt,R.A., Baross,A., Marra,M.A., Clifton,S.,
            Makowski,K.A., Bosak,S. and Malek,J.
  CONSRTM   MGC Project Team
  TITLE     The status, quality, and expansion of the NIH full-length cDNA
            project: the Mammalian Gene Collection (MGC)
  JOURNAL   Genome Res 14 (10B), 2121-2127 (2004)
   PUBMED   15489334
  REMARK    Erratum:[Genome Res. 2006 Jun;16(6):804. Morrin, Ryan [corrected to
            Morin, Ryan]]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC003682.1.
            
            On Nov 23, 2018 this sequence version replaced NM_017879.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC000130.1, SRR1660805.116016.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000196489.4/ ENSP00000196489.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-240               AC003682.1         67384-67623         c
            241-282             AC003682.1         66769-66810         c
            283-409             AC003682.1         64516-64642         c
            410-2545            AC003682.1         60278-62413         c
FEATURES             Location/Qualifiers
     source          1..2545
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..2545
                     /gene="ZNF416"
                     /note="zinc finger protein 416"
                     /db_xref="GeneID:55659"
                     /db_xref="HGNC:HGNC:20645"
     exon            1..240
                     /gene="ZNF416"
                     /inference="alignment:Splign:2.1.0"
     CDS             208..1992
                     /gene="ZNF416"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 416 isoform 1"
                     /protein_id="NP_060349.1"
                     /db_xref="CCDS:CCDS12954.1"
                     /db_xref="GeneID:55659"
                     /db_xref="HGNC:HGNC:20645"
                     /translation="MAAAVLRDSTSVPVTAEAKLMGFTQGCVTFEDVAIYFSQEEWGL
                     LDEAQRLLYRDVMLENFALITALVCWHGMEDEETPEQSVSVEGVPQVRTPEASPSTQK
                     IQSCDMCVPFLTDILHLTDLPGQELYLTGACAVFHQDQKHHSAEKPLESDMDKASFVQ
                     CCLFHESGMPFTSSEVGKDFLAPLGILQPQAIANYEKPNKISKCEEAFHVGISHYKWS
                     QCRRESSHKHTFFHPRVCTGKRLYESSKCGKACCCECSLVQLQRVHPGERPYECSECG
                     KSFSQTSHLNDHRRIHTGERPYVCGQCGKSFSQRATLIKHHRVHTGERPYECGECGKS
                     FSQSSNLIEHCRIHTGERPYECDECGKAFGSKSTLVRHQRTHTGEKPYECGECGKLFR
                     QSFSLVVHQRIHTTARPYECGQCGKSFSLKCGLIQHQLIHSGARPFECDECGKSFSQR
                     TTLNKHHKVHTAERPYVCGECGKAFMFKSKLVRHQRTHTGERPFECSECGKFFRQSYT
                     LVEHQKIHTGLRPYDCGQCGKSFIQKSSLIQHQVVHTGERPYECGKCGKSFTQHSGLI
                     LHRKSHTVERPRDSSKCGKPYSPRSNIV"
     exon            241..282
                     /gene="ZNF416"
                     /inference="alignment:Splign:2.1.0"
     exon            283..409
                     /gene="ZNF416"
                     /inference="alignment:Splign:2.1.0"
     exon            410..2545
                     /gene="ZNF416"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2521..2526
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF416"
                     /note="hexamer: AATAAA"
     polyA_site      2545
                     /gene="ZNF416"
                     /note="major polyA site"
ORIGIN      
        1 gggacttccg gcaccgctcc gagatggtaa ttttggtggt tctctacctc ggcccacgcc
       61 gcctgagtta gaaacgctgc ctccggcaca gagcgggggt cgccccgctg cgcatcagcc
      121 ggtgggtcgc tggcgctggt ggcagccgtg cctgggttcc cgccccgggt cgcccgccgc
      181 tcccggcccc gctccgctca caatccgatg gcggcggccg tgcttaggga ttcgacttcg
      241 gttcccgtga ctgcagaagc taaacttatg ggctttacac agggctgtgt gacctttgag
      301 gacgtggcca tttacttctc ccaggaagaa tgggggctcc ttgatgaggc tcagaggctc
      361 ctgtaccgcg atgtgatgct ggagaacttt gcacttataa ctgcgctggt ttgttggcat
      421 gggatggagg atgaagagac acctgagcaa agtgtttctg tagaaggagt acctcaggtc
      481 aggactccag aggccagtcc atccacccag aagattcaat cctgtgacat gtgtgtccca
      541 ttcctgaccg acattttgca cctgaccgat ttgcctgggc aggaactata cttgactggg
      601 gcatgtgcgg tctttcacca ggaccagaag catcatagtg cagagaaacc cttggaaagt
      661 gacatggaca aggcctcatt tgtgcagtgc tgcctgttcc atgagtcagg aatgcctttc
      721 accagcagtg aggttgggaa ggacttccta gccccattgg gcattcttca gccgcaagct
      781 attgctaact atgagaagcc aaacaaaatc agcaaatgtg aggaggcctt tcatgttgga
      841 ataagtcatt acaagtggag tcaatgcagg agagagtcca gccacaaaca cacttttttt
      901 caccctagag tctgcactgg aaaaaggctt tatgaatcta gcaaatgtgg gaaagcctgc
      961 tgctgtgagt gctcccttgt tcagctgcaa agagtccacc ctggagaaag gccttatgag
     1021 tgcagtgaat gtgggaaatc ttttagccaa acctctcatc tgaatgatca tcggagaatc
     1081 cacactggag aaaggcctta tgtgtgtggt cagtgtggga aatcatttag ccaaagagcc
     1141 accctcatta aacatcacag agttcacact ggagaaaggc cttacgagtg tggtgaatgt
     1201 gggaaatctt ttagccaaag ttccaacctt attgaacatt gcagaattca cactggagaa
     1261 aggccttatg agtgtgatga atgtggaaaa gcctttgggt ccaaatccac tcttgttcga
     1321 caccagagaa ctcacacagg agaaaagcca tatgagtgtg gtgaatgtgg gaaattattc
     1381 agacaaagct tcagccttgt tgtacaccag agaattcaca ctacagcaag gccttatgag
     1441 tgtggccagt gtgggaaatc atttagccta aagtgtggcc tcattcagca ccagttaatt
     1501 cacagtggag ctaggccctt tgagtgtgat gagtgcggaa aatcctttag ccaaagaacc
     1561 accctcaata aacaccacaa agttcacact gcagaaaggc cttatgtatg tggggaatgt
     1621 gggaaagctt ttatgttcaa atctaaactt gttaggcacc agagaactca cactggagaa
     1681 aggccttttg agtgcagtga atgtgggaaa ttttttagac aaagctatac cctcgttgaa
     1741 caccagaaaa ttcacactgg attaaggcct tacgactgtg gacagtgcgg gaaatccttt
     1801 atccaaaagt ctagcctcat tcaacaccaa gtggttcaca caggagaaag gccatatgag
     1861 tgtggcaaat gtgggaagtc ctttacacaa cactctggcc tcattctcca ccgaaaatct
     1921 cacactgtgg agaggcctcg tgacagcagc aaatgtggaa aaccctacag cccaagatct
     1981 aacattgttt aactcttgaa actccaaacc tgagaaaagc cttagacctg cagggaatgt
     2041 gccatgtctt tcttcagtgt tatggctata gagagccttt gtgaaggagc cgtctgccta
     2101 aagttaaacc tcatacttct agacctcccg atgggtcaga ctcccattag ttccaggcat
     2161 atgtgtcttg caggagctcc tttgcatgtt ctaaactgct ggaggccttt gccagagtta
     2221 aatcattagt cacccttgca tactaaggcg aggcagatac acctgtgttc tcccaaccct
     2281 tggaggaaat tccttgagca gtctgagcct ttaaggggaa ttccttccct tttctgactg
     2341 attacagcat acatctgacc agttttggcc agaagggccc agcctgggtt ctgctggaag
     2401 ctgatgtgga aggcttccct tcatggaaat tcttgttttc acacaacact tggtagtttt
     2461 tccagcctcc aagtcaccac ctagtaactg gctgcctcac attgctctgg tttgtgtggt
     2521 aataaaggcc ttatttttaa atcta
//
