LOCUS       NM_001392013            2899 bp    mRNA    linear   PRI 15-OCT-2024
DEFINITION  Homo sapiens zinc finger protein 385C (ZNF385C), transcript variant
            1, mRNA.
ACCESSION   NM_001392013
VERSION     NM_001392013.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2899)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 2899)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 2899)
  AUTHORS   Chen,S., Fragoza,R., Klei,L., Liu,Y., Wang,J., Roeder,K., Devlin,B.
            and Yu,H.
  TITLE     An interactome perturbation framework prioritizes damaging missense
            mutations for developmental disorders
  JOURNAL   Nat Genet 50 (7), 1032-1040 (2018)
   PUBMED   29892012
REFERENCE   4  (bases 1 to 2899)
  AUTHORS   Yu,H., Tardivo,L., Tam,S., Weiner,E., Gebreab,F., Fan,C.,
            Svrzikapa,N., Hirozane-Kishikawa,T., Rietman,E., Yang,X.,
            Sahalie,J., Salehi-Ashtiani,K., Hao,T., Cusick,M.E., Hill,D.E.,
            Roth,F.P., Braun,P. and Vidal,M.
  TITLE     Next-generation sequencing to generate interactome datasets
  JOURNAL   Nat Methods 8 (6), 478-480 (2011)
   PUBMED   21516116
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC105024.8.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA1965299, SAMEA1968189
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000692273.1/ ENSP00000509658.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                AC105024.8         120179-120242       c
            65-316              AC105024.8         84576-84827         c
            317-465             AC105024.8         59506-59654         c
            466-576             AC105024.8         55994-56104         c
            577-742             AC105024.8         53388-53553         c
            743-1033            AC105024.8         50552-50842         c
            1034-1230           AC105024.8         49819-50015         c
            1231-1341           AC105024.8         49387-49497         c
            1342-2899           AC105024.8         47345-48902         c
FEATURES             Location/Qualifiers
     source          1..2899
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.2"
     gene            1..2899
                     /gene="ZNF385C"
                     /note="zinc finger protein 385C"
                     /db_xref="GeneID:201181"
                     /db_xref="HGNC:HGNC:33722"
                     /db_xref="MIM:620982"
     exon            1..64
                     /gene="ZNF385C"
                     /inference="alignment:Splign:2.1.0"
     exon            65..316
                     /gene="ZNF385C"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..1578
                     /gene="ZNF385C"
                     /note="isoform 1 is encoded by transcript variant 1;
                     CTD-2132N18.4; CTD-2132N18.2"
                     /codon_start=1
                     /product="zinc finger protein 385C isoform 1"
                     /protein_id="NP_001378942.1"
                     /db_xref="CCDS:CCDS92306.1"
                     /db_xref="GeneID:201181"
                     /db_xref="HGNC:HGNC:33722"
                     /db_xref="MIM:620982"
                     /translation="MKRPLSPPPPAEKETPISGAAECLPRPPEPPKPKRERKRPSYTL
                     CDVCNIQLNSAAQAQVHCGGRAHQRRLRQLSLGKSPSGPAGPASGAPSPLLASLPLPT
                     RPLQPPLDFKHLLAFHFNGAAPLSLFPNFSTMDPVQKAVISHTFGVPSPLKKKLFISC
                     NICHLRFNSANQAEAHYKGHKHARKLKAVEAAKSKQRPHTQAQDGAVVSPIPTLASGA
                     PGEPQSKVPAAPPLGPPLQPPPTPDPTCREPAHSELLDAASSSSSSSCPPCSPEPGRE
                     APGPEPAAAAVGSSMSGEGRSEKGHLYCPTCKVTVNSASQLQAHNTGAKHRWMMEGQR
                     GAPRRSRGRPVSRGGAGHKAKRVTGGRGGRQGPSPAFHCALCQLQVNSETQLKQHMSS
                     RRHKDRLAGKTPKPSSQHSKLQKHAALAVSILKSKLALQKQLTKTLAARFLPSPLPTA
                     ATAICALPGPLALRPAPTAATTLFPAPILGPALFRTPAGAVRPATGPIVLAPY"
     exon            317..465
                     /gene="ZNF385C"
                     /inference="alignment:Splign:2.1.0"
     exon            466..576
                     /gene="ZNF385C"
                     /inference="alignment:Splign:2.1.0"
     exon            577..742
                     /gene="ZNF385C"
                     /inference="alignment:Splign:2.1.0"
     exon            743..1033
                     /gene="ZNF385C"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1230
                     /gene="ZNF385C"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..1341
                     /gene="ZNF385C"
                     /inference="alignment:Splign:2.1.0"
     exon            1342..2899
                     /gene="ZNF385C"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2882..2887
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF385C"
                     /note="hexamer: AATGAA"
     polyA_site      2899
                     /gene="ZNF385C"
                     /note="major polyA site"
ORIGIN      
        1 acacgcagcg ttcccagcca ggcgagagca ggtggccgcg gcgggctccg tctctgcccc
       61 gcagatatga agcggccact gagcccaccc ccaccggctg agaaggagac ccccatatct
      121 ggagctgctg agtgcctccc tcggccccca gaaccaccta agcccaagcg agaaagaaag
      181 cggccatcgt acacgctctg tgatgtctgc aacatccagc tgaactcggc ggcccaggcc
      241 caggtgcact gtggggggcg ggcccaccag aggcggcttc ggcagctcag cttggggaag
      301 agcccctcag ggccagcagg cccggcctcc ggcgccccca gccccctgct ggcctccctg
      361 cccctgccca cccggcctct gcagcccccg ctggacttca agcacttgct cgccttccac
      421 ttcaatggcg ctgccccgct cagtctcttc cccaacttca gcacgatgga cccggtccag
      481 aaagctgtca tcagccacac gtttggtgtc ccctcccctc tgaagaagaa gctgttcatt
      541 tcctgtaaca tctgtcacct gaggttcaac tcagcgaacc aggccgaggc acattataaa
      601 ggccacaaac acgccagaaa actcaaggct gtcgaggctg ccaagagcaa gcagaggcca
      661 cacacccagg cccaggatgg ggctgtagtg tccccaatcc caacgctggc cagtggagcc
      721 cctggagagc cacagagtaa agttcctgca gcccctcctc ttgggcctcc actccagcca
      781 ccaccaactc cagaccctac atgcagggag ccagcccact cagagctctt ggatgctgcc
      841 tcctcatcct cttcttcctc ctgcccacct tgctccccag agcctgggag agaggcaccg
      901 gggcctgagc cagcggcagc tgccgtggga agcagcatga gtggggaagg caggagtgag
      961 aaggggcacc tctactgccc cacgtgtaag gtgacagtga actcggcctc ccagcttcag
     1021 gctcacaaca caggagccaa gcaccggtgg atgatggaag gtcagcgagg ggctccccgg
     1081 aggagccggg gccgcccggt gtccagggga ggtgccggac acaaagccaa gagagtcaca
     1141 gggggccggg gcggccggca ggggcccagc cctgccttcc actgtgctct ctgtcagctc
     1201 caggtcaatt cagagaccca actgaagcag cacatgagca gcaggaggca caaagaccgc
     1261 ctggccggga agacccccaa gccctccagc cagcacagca agctgcagaa gcacgcagcg
     1321 ctggctgtga gtatcctcaa gtctaaactg gccttgcaga agcaactcac caagacgttg
     1381 gcagcccgct tcctgcccag cccgctcccc accgcagcca ctgccatctg tgctctgcca
     1441 gggcccctgg ccctccgccc tgcccctaca gcagccacta ccctcttccc ggctcccatc
     1501 ctgggcccag ctctgtttcg caccccagca ggagctgtcc gccctgccac aggacctatc
     1561 gtccttgccc cttattagcc ctcatgggga ggccagagct gatttcccaa tagccactcc
     1621 ttgtctcctc ctgtcctgag acaccttggt ttcctacatg ccacagggac tgtgaacagc
     1681 ttcaggggtc ctgcccgatc cagaaagagc tgggctagtt ttaagggcag ctgccttcca
     1741 aggactgtcc ccaccctcct ttcgcaggcc ttccagggtt aatcctaggc ttgcctgcat
     1801 ttcccaccct gacagacccc aaagatctat gcaaaatctc agccccagcc atgtggtgct
     1861 ctcactttcc tccacccaag acccacatgg ccagactcta ggaatcttag cttctacaag
     1921 ccatcctctc ctagccaggg gacgactctc tgacctctat tcctaggctt tggggcttca
     1981 ctggagatag ggatggggtc tctagctgca gcaggctcaa ggctgtcagg acaaggtgac
     2041 catgggagtg tgacagagga ccatggagga gaaaggggga cccaaaagtc cttcgatcag
     2101 cagtgctaag gtggggcaga gccaaggagg tagtggggct ggttctgaaa gcttttgggg
     2161 gcttcatctg ctctgaaggg gtgggactaa gagaggaggt gatgttctgg ttgggcccag
     2221 ggttttgttt taatcttaag tcttctgggc attcatgggc ccagtctttt tttctgtctg
     2281 agagtatcat tctgttgccc aggttagagt gcagtggtgc aatcttggct cactgcatgc
     2341 agcctctgcc tccctggttc aagtgatact tgctgataag cccagtctta atattgaggg
     2401 agtaactcat ccctcagaag ctcttcttct tagcctttct ctgacttcct gaaccccaac
     2461 tcttggaggg cgggtgtggg tctccctcag actatggact cagctaacac cgaacccccc
     2521 gcagagctcc caaaggaaga gctttcccct acagcttccc actccaaact ggtcctagca
     2581 ctaaattcag ctttcccttc tcccaaccag cccctgccac tgtgaagctg agtgttggga
     2641 ggcagtctca catgcactgg caagacccat tttcatgctg tcaatgtcaa tgtcacaaac
     2701 tcctttccac tgcagcactg ccccctcccc accccacaat atgggaccct gccagtatcc
     2761 ccctgtatct tttttttgtt ttttaaagac atttccaatg ggagaaccag aaaaaggggg
     2821 aggggaggga aactttttga taacaattgt ggttttattg tgtccaacca atgcatcaat
     2881 aaatgaactt gaagcccaa
//
