LOCUS       NM_001324250            8119 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens zinc finger protein 37A (ZNF37A), transcript variant
            9, mRNA.
ACCESSION   NM_001324250 XM_005252581
VERSION     NM_001324250.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8119)
  AUTHORS   Liu,J., Huang,Z., Chen,H.N., Qin,S., Chen,Y., Jiang,J., Zhang,Z.,
            Luo,M., Ye,Q., Xie,N., Zhou,Z.G., Wei,Y., Xie,K. and Huang,C.
  TITLE     ZNF37A promotes tumor metastasis through transcriptional control of
            THSD4/TGF-beta axis in colorectal cancer
  JOURNAL   Oncogene 40 (19), 3394-3407 (2021)
   PUBMED   33875786
  REMARK    GeneRIF: ZNF37A promotes tumor metastasis through transcriptional
            control of THSD4/TGF-beta axis in colorectal cancer.
REFERENCE   2  (bases 1 to 8119)
  AUTHORS   Gauthier,M., Marteyn,A., Denis,J.A., Cailleret,M.,
            Giraud-Triboult,K., Aubert,S., Lecuyer,C., Marie,J., Furling,D.,
            Vernet,R., Yanguas,C., Baldeschi,C., Pietu,G., Peschanski,M. and
            Martinat,C.
  TITLE     A defective Krab-domain zinc-finger transcription factor
            contributes to altered myogenesis in myotonic dystrophy type 1
  JOURNAL   Hum Mol Genet 22 (25), 5188-5198 (2013)
   PUBMED   23922231
  REMARK    GeneRIF: This suggests that the pathological molecular mechanisms
            linking ZNF37A and myogenesis may involve the signaling pathway
            that is known to promote myoblast recruitment during development
            and regeneration
REFERENCE   3  (bases 1 to 8119)
  AUTHORS   Vaquerizas,J.M., Kummerfeld,S.K., Teichmann,S.A. and Luscombe,N.M.
  TITLE     A census of human transcription factors: function, expression and
            evolution
  JOURNAL   Nat Rev Genet 10 (4), 252-263 (2009)
   PUBMED   19274049
  REMARK    Review article
REFERENCE   4  (bases 1 to 8119)
  AUTHORS   Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M.,
            French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S.,
            Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G.,
            Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P.,
            Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K.,
            Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C.,
            Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P.,
            Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N.,
            Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A.,
            Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C.,
            Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E.,
            Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E.,
            Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M.,
            Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M.,
            Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J.,
            Lovell,J., McLaren,S., McLay,K.E., McMurray,A.,
            Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T.,
            Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I.,
            Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A.,
            Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A.,
            Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J.,
            Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L.,
            Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C.,
            Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R.,
            Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 10
  JOURNAL   Nature 429 (6990), 375-381 (2004)
   PUBMED   15164054
REFERENCE   5  (bases 1 to 8119)
  AUTHORS   Guy,J., Hearn,T., Crosier,M., Mudge,J., Viggiano,L., Koczan,D.,
            Thiesen,H.J., Bailey,J.A., Horvath,J.E., Eichler,E.E.,
            Earthrowl,M.E., Deloukas,P., French,L., Rogers,J., Bentley,D. and
            Jackson,M.S.
  TITLE     Genomic sequence and transcriptional profile of the boundary
            between pericentromeric satellites and genes on human chromosome
            arm 10p
  JOURNAL   Genome Res 13 (2), 159-172 (2003)
   PUBMED   12566394
REFERENCE   6  (bases 1 to 8119)
  AUTHORS   Tunnacliffe,A., Liu,L., Moore,J.K., Leversha,M.A., Jackson,M.S.,
            Papi,L., Ferguson-Smith,M.A., Thiesen,H.J. and Ponder,B.A.
  TITLE     Duplicated KOX zinc finger gene clusters flank the centromere of
            human chromosome 10: evidence for a pericentric inversion during
            primate evolution
  JOURNAL   Nucleic Acids Res 21 (6), 1409-1417 (1993)
   PUBMED   8464732
REFERENCE   7  (bases 1 to 8119)
  AUTHORS   Huebner,K., Druck,T., Croce,C.M. and Thiesen,H.J.
  TITLE     Twenty-seven nonoverlapping zinc finger cDNAs from human T cells
            map to nine different chromosomes with apparent clustering
  JOURNAL   Am J Hum Genet 48 (4), 726-740 (1991)
   PUBMED   2014798
REFERENCE   8  (bases 1 to 8119)
  AUTHORS   Thiesen,H.J.
  TITLE     Multiple genes encoding zinc finger domains are expressed in human
            T cells
  JOURNAL   New Biol 2 (4), 363-374 (1990)
   PUBMED   2288909
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL117339.10.
            
            On Feb 1, 2021 this sequence version replaced NM_001324250.2.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.184553.1,
                                           SRR14038191.3180126.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000685332.1/ ENSP00000508865.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-154               AL117339.10        23777-23930
            155-448             AL117339.10        24371-24664
            449-540             AL117339.10        24978-25069
            541-601             AL117339.10        25184-25244
            602-660             AL117339.10        26014-26072
            661-787             AL117339.10        44195-44321
            788-883             AL117339.10        44635-44730
            884-8119            AL117339.10        46830-54065
FEATURES             Location/Qualifiers
     source          1..8119
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10p11.1"
     gene            1..8119
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /note="zinc finger protein 37A"
                     /db_xref="GeneID:7587"
                     /db_xref="HGNC:HGNC:13102"
                     /db_xref="MIM:616085"
     exon            1..154
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /inference="alignment:Splign:2.1.0"
     exon            155..448
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /inference="alignment:Splign:2.1.0"
     exon            449..540
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /inference="alignment:Splign:2.1.0"
     exon            541..601
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /inference="alignment:Splign:2.1.0"
     exon            602..660
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /inference="alignment:Splign:2.1.0"
     CDS             646..2331
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /note="isoform a is encoded by transcript variant 9; zinc
                     finger protein 37a (KOX 21); zinc finger protein KOX21"
                     /codon_start=1
                     /product="zinc finger protein 37A isoform a"
                     /protein_id="NP_001311179.1"
                     /db_xref="CCDS:CCDS31183.1"
                     /db_xref="GeneID:7587"
                     /db_xref="HGNC:HGNC:13102"
                     /db_xref="MIM:616085"
                     /translation="MITSQGSVSFRDVTVGFTQEEWQHLDPAQRTLYRDVMLENYSHL
                     VSVGYCIPKPEVILKLEKGEEPWILEEKFPSQSHLELINTSRNYSIMKFNEFNKGGKC
                     FCDEKHEIIHSEEEPSEYNKNGNSFWLNEDLIWHQKIKNWEQSFEYNECGKAFPENSL
                     FLVHKRGYTGQKTCKYTEHGKTCDMSFFITHQQTHPRENHYGNECGENIFEESILLEH
                     QSVYPFSQKLNLTPIQRTHSINNIIEYNECGTFFSEKLVLHLQQRTHTGEKPYECHEC
                     GKTFTQKSAHTRHQRTHTGGKPYECHECGKTFYKNSDLIKHQRIHTGERPYGCHECGK
                     SFSEKSTLTQHQRTHTGEKPYECHECGKTFSFKSVLTVHQKTHTGEKPYECYACGKAF
                     LRKSDLIKHQRIHTGEKPYECNECGKSFSEKSTLTKHLRTHTGEKPYECIQCGKFFCY
                     YSGFTEHLRRHTGEKPFGCNECGKTFRQKSALIVHQRTHIRQKPYGCNQCGKSFCVKS
                     KLIAHHRTHTGEKPYECNVCGKSFYVKSKLTVHQRIHLGRNPINVVNEGNYSG"
     exon            661..787
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /inference="alignment:Splign:2.1.0"
     exon            788..883
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /inference="alignment:Splign:2.1.0"
     exon            884..8119
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5224..5229
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /note="hexamer: AATAAA"
     polyA_site      5243
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
     regulatory      6807..6812
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /note="hexamer: AATAAA"
     polyA_site      6831
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /note="major polyA site"
     regulatory      8097..8102
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /note="hexamer: AGTAAA"
     polyA_site      8119
                     /gene="ZNF37A"
                     /gene_synonym="KOX21; ZNF37"
                     /note="major polyA site"
ORIGIN      
        1 gagatgtagt gtgcactttt cggcccccgt cgcgggagcc gcttcgggcc ttctgggcat
       61 gtctgccata tggctccagg tttgtttttc tccccggcac tctgacgggg agggctcccg
      121 gcatctcctg gcgtccgggt agaggacgcg gagggtcgca gcttcattgc ctgatgtctt
      181 cgggaagtat tttgaagtca tcgtggctgt ggattgggga atttcttgtt tccactgacc
      241 tgtgaggccg cgcacgcgga gggaggcacc ccaggccctc cggcactgtc cagcctcgcc
      301 tgtgtcccca ttagcaccag tgggcatttt cagagggtcc agctcatggc tcaagtgaca
      361 ggaagatgta ggagctttct gtcttgaatg aggattcgaa ccaaagggct taggcccagc
      421 tgtcttggag caaagcagct gttgtgggat gctgagctgc tggcgcactg cagcacaact
      481 agagatgtac ggatgccccc atcttgatct tacagaatca gaggtacagc cgcgagaaag
      541 agtcaagaac agacagagtc gcttgaggac tcaggagggt gtttgctgcg ttgacaacag
      601 actacaccct cacagtttgc tctgctcttc caacaccagt ggaagatgat cacatcccag
      661 ggatcagtgt cgtttaggga tgtgactgtg ggcttcactc aagaggagtg gcagcatctg
      721 gaccctgctc agaggaccct gtacagggat gtgatgctgg agaactacag ccaccttgtc
      781 tcagtagggt attgcattcc taaaccagaa gtgattctca agttggagaa aggcgaggag
      841 ccatggatat tagaggaaaa atttccaagc cagagtcatc tggaattaat taataccagt
      901 agaaactatt caataatgaa gttcaatgag tttaacaaag gtggaaaatg tttctgtgat
      961 gaaaagcatg aaataattca ttctgaagag gaaccttctg aatataataa aaatgggaac
     1021 agcttctggc tgaatgaaga cctcatttgg catcagaaaa ttaaaaattg ggaacaatct
     1081 tttgaataca atgaatgtgg gaaagctttc cctgagaatt cactcttcct tgtacataag
     1141 agaggttaca caggacagaa aacctgcaaa tatactgaac atgggaaaac ctgtgatatg
     1201 tcatttttca tcactcatca gcaaacacat ccaagagaaa accactatgg taatgaatgt
     1261 ggagaaaata tctttgagga atccattctc cttgaacatc agagtgttta cccattcagc
     1321 cagaagttaa atctcactcc aattcagaga acccactcaa ttaacaatat tattgaatat
     1381 aatgagtgtg gaacattttt cagtgaaaaa ttagtccttc atttacaaca gagaacacat
     1441 acaggagaaa aaccttatga atgtcatgaa tgtggaaaaa ccttcaccca gaagtcagcc
     1501 cacacaagac atcagagaac acacacaggg ggaaaaccct atgaatgtca tgaatgtggg
     1561 aagaccttct ataagaattc agacctcatt aaacatcaaa gaattcatac aggggagaga
     1621 ccttatggat gtcatgaatg tgggaaatcc ttcagtgaaa agtcaaccct tactcaacat
     1681 caaagaacgc acacagggga gaaaccatat gaatgtcatg aatgtgggaa aaccttctca
     1741 tttaagtcag tccttactgt gcatcagaaa acacacacag gggagaagcc ctatgaatgc
     1801 tatgcatgtg ggaaagcctt tctcagaaaa tcagacctca ttaaacatca aagaatacac
     1861 acaggtgaaa aaccttatga atgtaatgaa tgtgggaagt cattctctga gaagtcaacc
     1921 cttactaaac atctaagaac tcacacaggt gagaaacctt atgaatgtat tcagtgtgga
     1981 aaatttttct gctactactc cggtttcaca gaacatctga gaagacacac aggggagaaa
     2041 ccttttggat gtaatgaatg tgggaaaacc ttccgtcaga agtcagccct aattgttcac
     2101 cagagaactc atataagaca gaaaccctat ggatgtaatc aatgtggaaa atcattctgt
     2161 gtgaagtcaa aactcattgc acatcataga acacacacag gggagaaacc ctatgaatgt
     2221 aatgtttgtg gaaaatcatt ctatgttaag tcaaaactaa ctgtacatca gagaatacac
     2281 ttggggagaa accctataaa tgtagtaaac gagggaaatt actctgggtg aagtcagaac
     2341 tttgtagaac acagaacata aagggtgaga gaaatctgtt aatataatga taatgagaac
     2401 acctttgccc tgaagtcagt tctcacagta tagaagagaa cttaaagagg gaaaaaacaa
     2461 tatgaagata gggaatgcag gaaaacatta ttctggaatt tggaccatac actatgttac
     2521 aaaactaaaa gtggaaaaaa cttattggtg aatgaatata ggaaacattt tgcccaatgc
     2581 cactcttcat taaacatcag agaattcaca cggggtgaaa cctgggtcag catccctagg
     2641 ttgagaaggg atgcattttt ctgctactac tacagtttca cagaatacct gagaagacac
     2701 acttggagaa accttttggg tgtaatgaat gtgggaaaac ctttcatcag aagtcagctc
     2761 taattgttca ccacagaact catataagac agaaacccta tgggtgtaat gaatgtggaa
     2821 aatcattctg tgtgaagtca agaggccaga gaaaatgcac aaactgtagg aaactatagg
     2881 aaagcattta ctatgaggtt atattttatg gagtatatgt aataagaagt agcttctcag
     2941 tgaacatcag atagtagaga aagtattttt aactgtatcc aatgtgtgga tgttttaagt
     3001 taaaatctaa atttaatata gaacagaggt gttgagttgc aggatatcta gcaatttaag
     3061 aaaatgtgga aaaaatattt ttattgagaa atagcatttt actttgttaa tatctagttt
     3121 agttcattgt caagactgct attttctaag agacttctaa agacgccact caagccaatg
     3181 gctataagta gttcaaaggt ttattgctta gccatatgaa aaataaggga agatttttta
     3241 gcaaggggac ccacaaacaa gagtgctctt gtatgtccag aagaaagaga aagaccatca
     3301 atcaggggcc atagtacagg agcccaccag caggattttt gaataatcct agggcagact
     3361 aaattcagac gacccatctc agaatggtgg atcaaagcag caagtcaatt tgccttgtat
     3421 gcaacttatg aggattagta gaagagagtg ggtccagatt tctggtggtt tctgccctgc
     3481 agatgtctaa cacataagcc aggacattct gctgtgagtg acttattgta cccaactcta
     3541 tttctctcca tactgaaaca tgtctttcat aggtgataca actttttaaa atgtatgtgt
     3601 agatataact taaatatgga gctttcaaaa agcacaaata ggctggacat ggtggctcat
     3661 gcctgtaatc ccagtacttt gggaggctga ggtgggcaaa tcacctgagg tcaggagttc
     3721 cagaccagcc tggccaacat gatgaaaccc tgtctctact aaaaatacaa aaattagccg
     3781 ggcatggtgg tgcacatcgg tagtcctggc tactagagag gttgaggtgg gaggatcact
     3841 tgaacctggg aggtgggggt ttcagtgagc tgagatcatg ccactgcact ccagcctgag
     3901 tgacagagag agattcaaaa aacaaaaaaa aagcaaaaat atactttgct attgggtaag
     3961 gtatagtagt tggcagcaga atggacccat tgaggataac tataaaatta cagaaaatat
     4021 ttaaatgcaa cttattgcta tagaagcaaa gaggactaaa gggcaaaatt ctagagagtg
     4081 gtaaatctca gaaagcacaa gcataaaatg cagctctggg ggccctttcc acttctggct
     4141 atagggaaga acctgaatac tgaacttgat tcaggcagag gaccataacc tgggggtcag
     4201 gggaaggcat gggggggacc agaaaccaga agaacaatca agactgcaat gaaaaaaatg
     4261 gatacattag gagcttcaaa cacatataat ttctcaagaa atttccagat gtctcatgct
     4321 gcatagggca ggagcctgaa aagctaattt gagaagataa taagtaggat ttttgttttg
     4381 ttttgcattt tgcagtacaa aggagaaatg attagaactt aggaagtgcc agtgggttgg
     4441 tgaacatgcc atcagtaaaa gccctggaaa caaggtcata ctagagattg gttgtgcctt
     4501 gtcacaactg caaacaatac ctgagtggag tattcaaaaa cttgcttaga aagaaaactc
     4561 taggaacaga tggcttcact gaagttattc caaatattta agaaataata ccaggctttt
     4621 ataaactttt ctagaagaaa aaagatggaa cttttccaat tcagtttttg aggccagtac
     4681 aaccttgata acaaaaccta aaaaaaaaac aacaaaaaaa cccataaagc tatagaccaa
     4741 agtctcatag atttagatgc aaaatcctaa aattgaaaaa aacatctagc catatccata
     4801 aactatatca tcaccaagag atgtttatta gggcaatcaa aagatttatt attttaaaaa
     4861 aatcagtgtg gacttccatt cctctttctt ttgattcccc cctttgactt ttcatgtatc
     4921 tctcctgcct tccttcccca gagtggagga gttagacttg cctcgtggga tgagaggagt
     4981 tgtggctttg tgtctgctgg caccaagagg gctgagggtg aggtgtggaa gggacagggg
     5041 gaggagatgg gcagcattgt tgagagattg gtaacactga gcaaataaat atgttgagaa
     5101 tgatgacagc aagatttctc cattagagaa ggtatttata aaaataggaa tgaggagagc
     5161 tagaaaacct ggagtgtggc attagaatag aactcatatc ttttaaatat ataggaacaa
     5221 ataaataaat tgttgtgtgt gcacatatgc atatattttg tgttcattct actgagagga
     5281 cctaaacaca atgacacctc agtaacagta agcacaccaa ctgccaagtt attagttcct
     5341 aaatactatc cacaaaaaag gggaacaggg atgattccta gtcagagatt gggagaaata
     5401 caagatgagc ctgaatcatc tcatgtacct gacagtaaga aaatactctg gctggtctca
     5461 gtggctcatg tctgtaattc tagcatgtta gaaggtcaag gtgggtgggt tgcttgagct
     5521 caggagtttg agaccagcct gggcaacatg gcacaattgt ctctacaaaa aatacaaaaa
     5581 ttagccaggc atggtggcat gcacctgtag tccgaggtac tcaggaggca gagacgtggg
     5641 aggatcgctt gagcctggga gattgaggct gcactgagct gtgatcgtgc cactgtactc
     5701 tagcctggaa gacagagtga gaccccatct caggaaaaaa gaaaaaaaaa aagatgtcat
     5761 tcagcaggtt aatggataaa ctgtggaaca tccagaaaac tttaacattc ttcaaagaaa
     5821 tagaaaacac aatcctaaaa tttatatggg aaccacaaaa gacttagaat agtcagctat
     5881 cctgagcaaa aggaatcaaa ctggaggaat catattacct gacttccaat tattcaacag
     5941 agctacagta accaaaacag catgatactg gcataacaac agacacatag gaacagtata
     6001 gacaacccag aaacaaattc atacatctat ggtgaccact tttgacaaag gaatgaagaa
     6061 catacactgg ggaaaagata atgtctttaa taaatggtgc tgggaaaact ggatatccat
     6121 atgcagaaga atgaaactag acccccatct cttagcatat acaaaaatca aaattaatta
     6181 aaaagttaaa tctaagacct caaactatga aacagctaaa agaaaacatc ggggaatctc
     6241 tccaggacat tggagtgggc aaagatttct tgtgtaatac ctgacaaaca ggcaaccaaa
     6301 gcaaaagtgg acaaatggga tcacatcaag ttaaaaatct tctgcattgc aaaggaaata
     6361 acaaagtgaa gagacaaccc atagaatgtg agataatatt tgcaaactat ccatctgtat
     6421 taggccattt ttgaagtact acaaagaaat acttgagact gagtaattta taaagaagag
     6481 gtttaattgg ctcacggttt tgcaggctgt acaggaagca tggtgctaac atctgatcag
     6541 cttgtaggga ggcatcagga agtttccaac catggtggaa ggcaaaaggg gaataagtat
     6601 ctcacatggc aggtgcaggg caaagagagg ggggaaggga agtgccacac aaccagatct
     6661 tgtgagtact cagattttgt gaggggtgct tgaggtcatg gatacccatt taccctgatg
     6721 tgtttataca catttcatac ctgtattaaa atatctcatg taccccataa acatatacac
     6781 ctactttgta cccacaaaaa tttaaaaata aagttaattt caatgtttaa agacttgtta
     6841 ttaaaataat agcagtttct ataaatttaa tatttcaata aaactcccag tatttattgt
     6901 taacactgga aaaagttttc caaaacgtat atggcagaaa tatgggcctt gatgtgagga
     6961 cagcatcaat taatgaggga tcctctccct tgatcaaaac accttccacc aagacccacc
     7021 tttaacgctg agcattacct ctcaaagtga gatttgggca gggactaata tccaaactgt
     7081 atcaacatct gacaaggtgt tcacaaccag aatatataag gagctataac aattctatag
     7141 aaaaaaaaat ctgatttaaa actgggcaaa aatctgaata gacgtttctc aaaagaagac
     7201 atacaaatgg caaacaggca tatgaaaagg tactcaacat cattgatcca ttagagaaat
     7261 gcaaatcaaa actacaataa gatatcatct caccccagtt aaaatgtctt ctctccaaaa
     7321 gacagataat aacaaatgct gaagaggatg tggagaaaag ggaaacctcg tgcactgtgg
     7381 aaatgttatt agtacaacca ctatggacaa caatttggag gtacctcaaa aactaaaaat
     7441 agagctatca tacaatccca caattccact ggtagttata taccccaaag acaggaaatc
     7501 agtatattga agatatatct gcaccgtgtt tactgtagca ctactcacaa tagccaagat
     7561 ttggaagcaa cctaagtgtc taacagcaga tgaatggata aataaaatat ggtacataaa
     7621 cacaatggag tactattcag ccataaaaaa gaatgagatc ctgtcatttg caacattgta
     7681 gatggaacta gagatcatta agtgaaataa gccaggcaca gcaagacaga catcatgttc
     7741 tgacgtattt gttggagcta aagatgaaaa caactgaact tatagagggt agaaggatgt
     7801 ttaccagagg cgggaaaggc agtgagggca tggtgagggg gaagtgggga atgttaacgg
     7861 gcacaaaatg tagaatgact aagacctagt atttgatagc acaaggttac tacagtcaat
     7921 aataattgtg cattttaaag gtataattga attgtaacac aaaggataaa tgcttgaggt
     7981 tatggatacc ccatttaccc tgatgtgatt attagacatt gcatgcctat atcaaaatat
     8041 atcatgtacc ccatagatat atacacctag tatgtaccca caaaaattaa aaataaagta
     8101 aaatttcaat gattaggaa
//
