LOCUS       NM_152493               3187 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 362 (ZNF362), transcript variant
            1, mRNA.
ACCESSION   NM_152493
VERSION     NM_152493.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3187)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 3187)
  AUTHORS   Dias Neto,E., Correa,R.G., Verjovski-Almeida,S., Briones,M.R.,
            Nagai,M.A., da Silva,W. Jr., Zago,M.A., Bordin,S., Costa,F.F.,
            Goldman,G.H., Carvalho,A.F., Matsukuma,A., Baia,G.S., Simpson,D.H.,
            Brunstein,A., de Oliveira,P.S., Bucher,P., Jongeneel,C.V.,
            O'Hare,M.J., Soares,F., Brentani,R.R., Reis,L.F., de Souza,S.J. and
            Simpson,A.J.
  TITLE     Shotgun sequencing of the human transcriptome with ORF expressed
            sequence tags
  JOURNAL   Proc Natl Acad Sci U S A 97 (7), 3491-3496 (2000)
   PUBMED   10737800
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL513327.34, BX283663.1, AW204855.1, BF743001.1 and AF318356.1.
            
            On Nov 23, 2018 this sequence version replaced NM_152493.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038194.245816.1,
                                           SRR14038197.1184211.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000539719.6/ ENSP00000446335.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-81                AL513327.34        54322-54402
            82-443              BX283663.1         2-363
            444-816             AW204855.1         17-389              c
            817-836             BF743001.1         343-362             c
            837-3187            AF318356.1         606-2956
FEATURES             Location/Qualifiers
     source          1..3187
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p35.1"
     gene            1..3187
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /note="zinc finger protein 362"
                     /db_xref="GeneID:149076"
                     /db_xref="HGNC:HGNC:18079"
     exon            1..163
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /inference="alignment:Splign:2.1.0"
     exon            164..289
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /inference="alignment:Splign:2.1.0"
     CDS             252..1514
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /note="rotund homolog"
                     /codon_start=1
                     /product="zinc finger protein 362"
                     /protein_id="NP_689706.2"
                     /db_xref="CCDS:CCDS377.1"
                     /db_xref="GeneID:149076"
                     /db_xref="HGNC:HGNC:18079"
                     /translation="MSRSSPSGKGHSRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKI
                     KEQLMAEKIRPPHLPPTSASSQQPLLVPPAPAESSQAVMSLPKLQQVPGLHPQAVPQP
                     DVALHARPATSTVTGLGLSTRTPSVSTSESSAGAGTGTGTSTPSTPTTTSQSRLIASS
                     PTLISGITSPPLLDSIKTIQGHGLLGPPKSERGRKKIKAENPGGPPVLVVPYPILASG
                     ETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRI
                     HLGVKPYHCSYCDKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQ
                     HNKDKPYKCPNCYRAYSDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSK
                     HTVVEHLVSHHSPQRTESPGIPVRISLI"
     exon            290..353
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /inference="alignment:Splign:2.1.0"
     exon            354..600
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /inference="alignment:Splign:2.1.0"
     exon            601..934
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /inference="alignment:Splign:2.1.0"
     exon            935..1159
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1238
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /inference="alignment:Splign:2.1.0"
     exon            1239..1397
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /inference="alignment:Splign:2.1.0"
     exon            1398..3187
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3166..3171
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /note="hexamer: AATAAA"
     polyA_site      3187
                     /gene="ZNF362"
                     /gene_synonym="lin-29; RN"
                     /note="major polyA site"
ORIGIN      
        1 agaagtgaac agcaggcgac ccggaaggtt tgcgcgcggc tccgcagcga gccagagccg
       61 gagcccgagc ccggagcctg tgccggagcc ccagcccggc cctgctcggg ccgccgggcg
      121 cggggctgcg gccgcgtccc ggaggcgccg ccagcacagc caggtgctgt tgggaacaca
      181 gaggaagtga ctggctgggg gttcagggaa agctccgtag aagagggaac acttgagctg
      241 ggtcttgaag gatgagtaga agttcaccaa gtgggaaagg acactctagg atggccgagc
      301 ctcgatttaa caacccctac ttctggcccc ctcctcccac catgcccagc cagctggaca
      361 acctggttct gattaacaag atcaaggagc agctgatggc cgagaagatc aggccgcctc
      421 acctgccgcc cacgtcggcc tcgtcgcagc agccgttgct agtgccgccg gcacccgccg
      481 agagcagcca ggccgtcatg tcgctgccca agctgcagca ggtgccgggg ctgcatccac
      541 aggcggtgcc gcagcccgac gtggcgctgc acgcacggcc ggccaccagc accgtcacag
      601 gtctggggct gtccacccgg accccgtctg tgagcacttc tgagtcaagc gcgggcgcgg
      661 gcacgggcac gggtaccagc accccgtcca cacccaccac caccagccag agccgcctca
      721 tcgcctcgtc ccccaccctc atctcaggga tcaccagccc ccctctcctg gactccatca
      781 agacaatcca gggccacggc ctgcttggcc cccccaagtc cgaacgcggc cgcaaaaaga
      841 tcaaggcgga gaacccgggg ggtccgcctg tccttgtagt cccctatccc atcctggcct
      901 cgggcgagac tgccaaggag ggcaagacgt acaggtgtaa ggtatgccca ctgacctttt
      961 tcaccaagtc agagatgcag atccactcca agtcgcacac agaggccaag ccccacaagt
     1021 gcccgcactg ctccaagtcc tttgccaacg cctcctacct ggcccagcac ctgcgcatcc
     1081 acctgggcgt caagccctac cactgctcct actgtgataa gtccttccgg cagctctccc
     1141 acctccagca gcacaccaga atccacacag gcgacagacc ctacaagtgc ccacatcctg
     1201 gctgcgagaa ggctttcact cagctctcca acctccagtc tcaccagcgc cagcacaaca
     1261 aggacaagcc ctacaagtgt cccaactgct accgggccta ttcggactcc gcttctttgc
     1321 agatccacct ctcggcccac gccatcaagc acgccaaggc ctactgctgc agcatgtgtg
     1381 ggcgggccta cacctcggag acctacctga tgaagcacat gtccaaacac acggtggtgg
     1441 agcacctggt gagccatcac tcgccccaga ggacggagtc ccccggcatc ccggtgcgaa
     1501 tctctctcat ctgagcccac tggaggcgcc gccccacccg gcccactggc agacacagac
     1561 ccaggcagca ccaggcccca gctccctccg ggggccctcc aggaaccacc aagctctctc
     1621 acgaccttcc caatcttcca gaaagcttgg tccgcagaag ccctgcctgg tccagtccgg
     1681 gggcggccag gccaactgca agattctgga ctgttttggt ggcatccaaa gacgatctca
     1741 gagcactttg aacctctctg ttgagttttc tttttgttcc ccacccttca cttgcttcac
     1801 tgtttttttt tttttcgttt ttttttttta agtttgtttt ggaaataaca gaaaagatat
     1861 ttattggcca ggaagttggt gctgctaaga ccgagaaatt taaagaatcg gacagatgga
     1921 cgcagagaac cagagggcaa tgtgggacct tctcttgcca tggcctcagg tcttgaggga
     1981 aggctcgggc ctaggtttct ggactgcaaa ggggaccccc aggtgggagg ggcaggaagc
     2041 agccggagtg agcccttcgc ccctgagtgc ctggctcgca cctctcgagc tgtgccctgg
     2101 gcatcactga gcagaggggt gcggcagctt caggaggcag aaacgagagg ggtgggagat
     2161 ccacaggacc aaagggtgca gtgatgggct gggtggcggg cccagggaaa tggggtgggg
     2221 atgggctggg taagacctgg ccctcccctg ctgccctgaa gaccacccca gtctacctcg
     2281 gtgctggcca ggaaaccttt cggctacctc tcccaccatc ccagactgtg ggcaggggga
     2341 tggggaggga gtgggcctgg atctgggacc tccctccaga atttcctcca gatgggggca
     2401 gtgcccaggg aggggttatt tgtcttccct gccatggagt gggaatcccc agccgaggcc
     2461 ctaggcccct cagcagggaa gggatccccg gggaggcagg tcccaggagc agaccctgcc
     2521 cccagccccc acagacacac cccaatctga aagccatgcg tgtcggtgta tataggaacc
     2581 atgtacagag cccagagaag ccccctacat ccccccggga aaaaaaagaa aactagacag
     2641 aaactcatct atatattctg tatctggagt tccgttttga atattaactg tgttattttt
     2701 atacactttt taagccttaa ctcgccattg atttaccagt ttaacgtttc ctggggtttc
     2761 tttgcccatg gggttctctg cccccacccc cggccctttg tttgacttgc gtcgtctgat
     2821 actcagtatt gtagcttttt gtccgcatgt tactccctgt aaatacgctg ttatacatac
     2881 tgttaacacc cctttgcttt ttctatggga cctccaggcc accatattta gaactagtta
     2941 ccttattaaa aaagaaaaaa cagtctgttg gcttctcagt ctgcatcttg gaggcaggga
     3001 ggtgagggca ggtgcccctc agacacttca ggaaggtagt ttgcattcta tttaaaaaag
     3061 ggagtgggga gcaaatgaaa atcaaatgtg gggggaaaac actaaagggg gcaagaaaca
     3121 aaggaattac aaaccctctg ctctttgtat ttctctgttg tgaagaataa actgtacctg
     3181 cacccgg
//
